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Data Status: November 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,642,894
Unique chemicals 12,560
Unique genes 43,854
Unique organisms 573
Gene–disease associations 21,617,678
Curated[1] 35,904
Unique genes 7,998
Unique diseases 5,682
Inferred[2] 21,581,774
Unique genes 42,872
Unique diseases 3,120
Chemical–disease associations 2,368,412
Curated[1] 208,801
Unique chemicals 9,394
Unique diseases 3,167
Inferred[2] 2,159,611
Unique chemicals 12,310
Unique diseases 5,669
Chemical–GO associations (enriched) 5,083,008
Chemical–pathway associations (enriched) 1,127,493
Disease–pathway associations (inferred) 275,284
Gene–gene interactions 477,483
Gene–GO annotations 1,246,761
Gene–pathway annotations 135,816
GO–disease associations (inferred) 915,871
Chemicals with curated data 15,368
Diseases with curated data 7,100
Via OMIM curation 4,070
Genes with curated data 43,919
Via OMIM curation 3,660
Curated references 122,370
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 103,837
Unique Chemicals 981
Unique Genes 331
Unique Diseases 376
Unique GO Terms 283
Curated Exposure References 1,825

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.154 release)
  2. ChemIDplus® (as of November 2, 2017)
  3. DrugBank (as of November 2, 2017)
  4. GO (as of November 2, 2017)
  5. KEGG (as of November 2, 2017)
  6. MeSH® (2017 MeSH release)
  7. NCBI Gene (as of November 2, 2017)
  8. NCBI Taxonomy (as of November 2, 2017)
  9. PubMed® (as of November 2, 2017)
  10. Reactome (as of November 2, 2017)