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Data Status: January 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,523,447
Unique chemicals 12,087
Unique genes 42,432
Unique organisms 566
Gene–disease associations 20,140,784
Curated[1] 34,258
Unique genes 8,142
Unique diseases 5,002
Inferred[2] 20,106,526
Unique genes 41,443
Unique diseases 3,093
Chemical–disease associations 2,143,567
Curated[1] 204,329
Unique chemicals 9,163
Unique diseases 3,141
Inferred[2] 1,939,238
Unique chemicals 11,823
Unique diseases 4,322
Chemical–GO associations (enriched) 4,686,784
Chemical–pathway associations (enriched) 316,094
Disease–pathway associations (inferred) 60,784
Gene–gene interactions 383,855
Gene–GO annotations 1,194,470
Gene–pathway annotations 71,080
GO–disease associations (inferred) 819,646
Chemicals with curated data 14,926
Diseases with curated data 6,413
Via OMIM curation 3,379
Genes with curated data 43,449
Via OMIM curation 3,378
Curated references 119,488
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 87,597
Unique Chemicals 888
Unique Genes 289
Unique Diseases 320
Unique GO Terms 240
Curated Exposure References 1,510

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.144 release)
  2. ChemIDplus® (as of January 3, 2017)
  3. DrugBank (as of January 3, 2017)
  4. GO (as of January 3, 2017)
  5. KEGG (as of January 3, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of January 3, 2017)
  8. NCBI Taxonomy (as of January 3, 2017)
  9. PubMed® (as of January 3, 2017)
  10. Reactome (as of January 3, 2017)