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Data Status: February 2018

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,721,510
Unique chemicals 12,648
Unique genes 44,750
Unique organisms 577
Phenotype–based interactions (curated) 165,742
Unique chemicals 6,479
Unique genes 1,638
Unique GO terms 3,919
Unique anatomical terms 766
Unique organisms 215
Gene–disease associations 23,047,678
Curated[1] 36,652
Unique genes 8,171
Unique diseases 5,736
Inferred[2] 23,011,026
Unique genes 43,771
Unique diseases 3,126
Chemical–disease associations 2,416,337
Curated[1] 209,811
Unique chemicals 9,433
Unique diseases 3,172
Inferred[2] 2,206,526
Unique chemicals 12,400
Unique diseases 5,723
Chemical–GO associations (enriched) 5,085,599
Chemical–pathway associations (enriched) 1,145,599
Disease–pathway associations (inferred) 278,795
Gene–gene interactions 485,900
Gene–GO annotations 1,168,570
Gene–pathway annotations 135,816
GO–disease associations (inferred) 930,383
Chemicals with curated data 15,446
Diseases with curated data 7,151
Via OMIM curation 4,117
Genes with curated data 44,823
Via OMIM curation 3,682
Curated references 127,939
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 111,174
Unique Chemicals 1,020
Unique Genes 340
Unique Diseases 386
Unique GO Terms 300
Curated Exposure References 1,938

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.157 release)
  2. ChemIDplus® (as of February 6, 2018)
  3. DrugBank (as of February 7, 2018)
  4. GO (as of February 6, 2018)
  5. KEGG (as of February 6, 2018)
  6. MeSH® (2018 MeSH release)
  7. NCBI Gene (as of February 6, 2018)
  8. NCBI Taxonomy (as of February 6, 2018)
  9. PubMed® (as of February 7, 2018)
  10. Reactome (as of February 6, 2018)