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Data Status: November 2016

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,509,482
Unique chemicals 12,045
Unique genes 41,964
Unique organisms 565
Gene–disease associations 20,042,051
Curated[1] 34,068
Unique genes 8,132
Unique diseases 4,995
Inferred[2] 20,007,983
Unique genes 40,955
Unique diseases 3,093
Chemical–disease associations 2,122,299
Curated[1] 203,778
Unique chemicals 9,149
Unique diseases 3,141
Inferred[2] 1,918,521
Unique chemicals 11,778
Unique diseases 4,314
Chemical–GO associations (enriched) 4,575,321
Chemical–pathway associations (enriched) 313,353
Disease–pathway associations (inferred) 60,486
Gene–gene interactions 382,568
Gene–GO annotations 1,188,605
Gene–pathway annotations 71,001
GO–disease associations (inferred) 809,159
Chemicals with curated data 14,884
Diseases with curated data 6,410
Via OMIM curation 3,380
Genes with curated data 42,982
Via OMIM curation 3,379
Curated references 118,989
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 80,148
Unique Chemicals 840
Unique Genes 245
Unique Diseases 315
Unique GO Terms 224
Curated Exposure References 1,425

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.142 release)
  2. ChemIDplus® (as of November 3, 2016)
  3. DrugBank (as of November 3, 2016)
  4. GO (as of November 3, 2016)
  5. KEGG (as of November 3, 2016)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of November 3, 2016)
  8. NCBI Taxonomy (as of November 3, 2016)
  9. PubMed® (as of November 3, 2016)
  10. Reactome (as of November 3, 2016)