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Data Status: November 2018

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,848,987
Unique chemicals 12,995
Unique genes 46,936
Unique organisms 584
Phenotype–based interactions (curated) 177,501
Unique chemicals 7,015
Unique genes 1,987
Unique GO terms 4,504
Unique anatomical terms 806
Unique organisms 236
Gene–disease associations 25,072,312
Curated[1] 38,056
Unique genes 8,422
Unique diseases 5,767
Inferred[2] 25,034,256
Unique genes 45,921
Unique diseases 3,152
Chemical–disease associations 2,542,883
Curated[1] 212,734
Unique chemicals 9,583
Unique diseases 3,195
Inferred[2] 2,330,149
Unique chemicals 12,753
Unique diseases 5,755
Chemical–GO associations (enriched) 5,280,234
Chemical–pathway associations (enriched) 1,195,566
Disease–pathway associations (inferred) 284,477
Gene–gene interactions 529,689
Gene–GO annotations 1,214,054
Gene–pathway annotations 135,805
GO–disease associations (inferred) 2,019,686
Chemicals with curated data 15,776
Diseases with curated data 7,189
Via OMIM curation 4,129
Genes with curated data 47,007
Via OMIM curation 3,681
Curated references 130,195
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 126,410
Unique Chemicals 1,175
Unique Genes 442
Unique Diseases 427
Unique GO Terms 356
Curated Exposure References 2,230

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.5.166 release)
  2. ChemIDplus® (as of November 7, 2018)
  3. DrugBank (as of November 7, 2018)
  4. GO (as of November 7, 2018)
  5. KEGG (as of November 7, 2018)
  6. MeSH® (2019 MeSH release)
  7. NCBI Gene (as of November 7, 2018)
  8. NCBI Taxonomy (as of November 7, 2018)
  9. PubMed® (as of November 7, 2018)
  10. Reactome (as of November 7, 2018)