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Data Status: August 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,613,109
Unique chemicals 12,420
Unique genes 43,656
Unique organisms 571
Gene–disease associations 21,331,472
Curated[1] 35,496
Unique genes 7,896
Unique diseases 5,532
Inferred[2] 21,295,976
Unique genes 42,665
Unique diseases 3,112
Chemical–disease associations 2,325,331
Curated[1] 207,593
Unique chemicals 9,322
Unique diseases 3,161
Inferred[2] 2,117,738
Unique chemicals 12,164
Unique diseases 5,519
Chemical–GO associations (enriched) 4,944,213
Chemical–pathway associations (enriched) 1,109,169
Disease–pathway associations (inferred) 273,061
Gene–gene interactions 472,712
Gene–GO annotations 1,229,302
Gene–pathway annotations 135,814
GO–disease associations (inferred) 898,445
Chemicals with curated data 15,248
Diseases with curated data 6,952
Via OMIM curation 3,922
Genes with curated data 43,720
Via OMIM curation 3,546
Curated references 121,724
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 97,676
Unique Chemicals 955
Unique Genes 325
Unique Diseases 359
Unique GO Terms 268
Curated Exposure References 1,731

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.151 release)
  2. ChemIDplus® (as of August 18, 2017)
  3. DrugBank (as of August 18, 2017)
  4. GO (as of August 18, 2017)
  5. KEGG (as of August 18, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of August 18, 2017)
  8. NCBI Taxonomy (as of August 18, 2017)
  9. PubMed® (as of August 18, 2017)
  10. Reactome (as of August 18, 2017)