| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | NOG | 16,683 | 3 |
| 2. | ESR1 | 1,824 | 42 |
| 3. | TNF | 1,735 | 17 |
| 4. | PPARA | 1,550 | 16 |
| 5. | CASP3 | 1,016 | 15 |
| 6. | PTGS2 | 1,004 | 15 |
| 7. | MAPK1 | 898 | 12 |
| 8. | ESR2 | 896 | 18 |
| 9. | MAPK3 | 879 | 12 |
| 10. | IL1B | 843 | 15 |
| 11. | CYP1A1 | 808 | 30 |
| 12. | IL6 | 732 | 9 |
| 13. | BCL2 | 617 | 11 |
| 14. | SIRT1 | 591 | 11 |
| 15. | AR | 589 | 14 |
| 16. | HMOX1 | 566 | 8 |
| 17. | TP53 | 565 | 12 |
| 18. | RELA | 557 | 12 |
| 19. | AHR | 542 | 15 |
| 20. | NOS2 | 535 | 8 |
| 21. | PPARG | 513 | 14 |
| 22. | NFE2L2 | 493 | 9 |
| 23. | CAT | 481 | 36 |
| 24. | BAX | 460 | 9 |
| 25. | CXCL8 | 436 | 5 |
| 26. | IFNG | 434 | 8 |
| 27. | CCND1 | 418 | 7 |
| 28. | CYP2E1 | 409 | 10 |
| 29. | AKT1 | 399 | 7 |
| 30. | CCL2 | 391 | 6 |
| 31. | NQO1 | 383 | 12 |
| 32. | TRPV1 | 371 | 13 |
| 33. | MMP9 | 357 | 7 |
| 34. | CDKN1A | 356 | 6 |
| 35. | PARP1 | 348 | 5 |
| 36. | TGFB1 | 328 | 6 |
| 37. | AGT | 327 | 8 |
| 38. | CYP1A2 | 318 | 10 |
| 39. | VEGFA | 314 | 7 |
| 40. | CASP9 | 312 | 7 |
| 41. | STAT3 | 306 | 10 |
| 42. | EGFR | 287 | 5 |
| 43. | FOS | 285 | 10 |
| 44. | MPO | 279 | 6 |
| 45. | SOD2 | 276 | 15 |
| 46. | NOS3 | 271 | 8 |
| 47. | EGF | 263 | 4 |
| 48. | NR1I2 | 263 | 9 |
| 49. | JUN | 252 | 9 |
| 50. | NFKBIA | 248 | 8 |