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Illuminating how chemicals affect human health.
N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochlorideThese GO terms are enriched significantly among genes that interact with N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride. We show only terms with a corrected p-value <0.01.
| Ontology | Highest GO Level | GO Term | P-value | Corrected P-value | Annotated Genes | Genome Frequency | |
|---|---|---|---|---|---|---|---|
| 1. | CC | 2 | intracellular part | 2.24e-24 | 6.52e-21 | 57 | 13333/42493 genes: 31.38% |
| 2. | CC | 2 | intracellular | 6.60e-24 | 1.92e-20 | 57 | 13596/42493 genes: 32.00% |
| 3. | CC | 1 | cell part | 6.02e-22 | 1.75e-18 | 58 | 15648/42493 genes: 36.82% |
| 4. | CC | 1 | cell | 6.71e-22 | 1.95e-18 | 58 | 15678/42493 genes: 36.90% |
| 5. | BP | 1 | cellular process | 1.05e-19 | 3.05e-16 | 55 | 14530/42493 genes: 34.19% |
| 6. | CC | 2 | membrane-bounded organelle | 1.28e-18 | 3.73e-15 | 50 | 11713/42493 genes: 27.56% |
| 7. | BP | 1 | single-organism process | 3.03e-18 | 8.83e-15 | 51 | 12581/42493 genes: 29.61% |
| 8. | CC | 1 | organelle | 3.82e-18 | 1.11e-14 | 51 | 12643/42493 genes: 29.75% |
| 9. | CC | 3 | cytoplasm | 1.84e-17 | 5.36e-14 | 47 | 10590/42493 genes: 24.92% |
| 10. | BP | 2 | single-organism cellular process | 3.73e-17 | 1.09e-13 | 46 | 10200/42493 genes: 24.00% |
| 11. | MF | 1 | binding | 4.78e-17 | 1.39e-13 | 52 | 14042/42493 genes: 33.05% |
| 12. | CC | 2 | intracellular organelle | 9.38e-16 | 2.73e-12 | 47 | 11621/42493 genes: 27.35% |
| 13. | BP | 1 | metabolic process | 4.65e-15 | 1.35e-11 | 45 | 10886/42493 genes: 25.62% |
| 14. | BP | 3 | cell cycle | 8.53e-15 | 2.48e-11 | 21 | 1684/42493 genes: 3.96% |
| 15. | CC | 3 | intracellular membrane-bounded organelle | 9.67e-15 | 2.81e-11 | 43 | 9968/42493 genes: 23.46% |
| 16. | CC | 3 | cytoplasmic part | 1.17e-14 | 3.39e-11 | 41 | 8966/42493 genes: 21.10% |
| 17. | BP | 2 | cellular metabolic process | 1.27e-14 | 3.69e-11 | 43 | 10040/42493 genes: 23.63% |
| 18. | MF | 2 | protein binding | 1.36e-13 | 3.97e-10 | 43 | 10697/42493 genes: 25.17% |
| 19. | CC | 1 | organelle part | 1.92e-13 | 5.59e-10 | 39 | 8668/42493 genes: 20.40% |
| 20. | BP | 3 | mitotic cell cycle process | 2.20e-13 | 6.42e-10 | 15 | 772/42493 genes: 1.82% |
| 21. | CC | 2 | intracellular organelle part | 5.86e-13 | 1.71e-9 | 38 | 8460/42493 genes: 19.91% |
| 22. | BP | 3 | response to toxic substance | 6.12e-13 | 1.78e-9 | 10 | 214/42493 genes: 0.50% |
| 23. | BP | 4 | mitotic cell cycle | 1.55e-12 | 4.51e-9 | 15 | 885/42493 genes: 2.08% |
| 24. | BP | 2 | organic substance metabolic process | 2.22e-12 | 6.46e-9 | 41 | 10399/42493 genes: 24.47% |
| 25. | BP | 5 | G1/S transition of mitotic cell cycle | 3.36e-12 | 9.79e-9 | 10 | 254/42493 genes: 0.60% |
| 26. | CC | 4 | nucleus | 4.22e-12 | 1.23e-8 | 33 | 6619/42493 genes: 15.58% |
| 27. | BP | 4 | cell cycle G1/S phase transition | 5.93e-12 | 1.73e-8 | 10 | 269/42493 genes: 0.63% |
| 28. | BP | 3 | regulation of cell cycle | 7.79e-12 | 2.27e-8 | 15 | 992/42493 genes: 2.33% |
| 29. | BP | 1 | biological regulation | 8.06e-12 | 2.35e-8 | 41 | 10793/42493 genes: 25.40% |
| 30. | CC | 4 | cytosol | 1.00e-11 | 2.91e-8 | 28 | 4758/42493 genes: 11.20% |
| 31. | BP | 2 | cell cycle process | 1.30e-11 | 3.78e-8 | 16 | 1229/42493 genes: 2.89% |
| 32. | CC | 3 | nuclear part | 1.58e-11 | 4.59e-8 | 26 | 4107/42493 genes: 9.67% |
| 33. | CC | 3 | intracellular non-membrane-bounded organelle | 1.73e-11 | 5.04e-8 | 25 | 3773/42493 genes: 8.88% |
| 34. | CC | 2 | non-membrane-bounded organelle | 1.73e-11 | 5.04e-8 | 25 | 3773/42493 genes: 8.88% |
| 35. | CC | 4 | nuclear lumen | 2.00e-11 | 5.82e-8 | 25 | 3798/42493 genes: 8.94% |
| 36. | BP | 1 | response to stimulus | 5.30e-11 | 1.54e-7 | 35 | 8202/42493 genes: 19.30% |
| 37. | BP | 6 | regulation of G1/S transition of mitotic cell cycle | 7.24e-11 | 2.11e-7 | 8 | 157/42493 genes: 0.37% |
| 38. | MF | 1 | catalytic activity | 7.98e-11 | 2.32e-7 | 28 | 5190/42493 genes: 12.21% |
| 39. | BP | 2 | primary metabolic process | 1.26e-10 | 3.67e-7 | 38 | 10009/42493 genes: 23.55% |
| 40. | BP | 5 | regulation of cell cycle G1/S phase transition | 1.50e-10 | 4.37e-7 | 8 | 172/42493 genes: 0.40% |
| 41. | BP | 2 | regulation of cellular process | 1.75e-10 | 5.09e-7 | 37 | 9578/42493 genes: 22.54% |
| 42. | BP | 4 | intrinsic apoptotic signaling pathway | 1.86e-10 | 5.41e-7 | 9 | 269/42493 genes: 0.63% |
| 43. | BP | 6 | negative regulation of G1/S transition of mitotic cell cycle | 2.05e-10 | 5.97e-7 | 7 | 107/42493 genes: 0.25% |
| 44. | BP | 1 | regulation of biological process | 2.53e-10 | 7.36e-7 | 38 | 10235/42493 genes: 24.09% |
| 45. | BP | 2 | response to stress | 2.62e-10 | 7.64e-7 | 23 | 3564/42493 genes: 8.39% |
| 46. | BP | 4 | mitotic cell cycle phase transition | 2.80e-10 | 8.16e-7 | 11 | 537/42493 genes: 1.26% |
| 47. | BP | 5 | negative regulation of cell cycle G1/S phase transition | 2.83e-10 | 8.25e-7 | 7 | 112/42493 genes: 0.26% |
| 48. | CC | 4 | nucleoplasm | 3.22e-10 | 9.38e-7 | 22 | 3261/42493 genes: 7.67% |
| 49. | BP | 3 | organic cyclic compound metabolic process | 3.38e-10 | 9.84e-7 | 29 | 5940/42493 genes: 13.98% |
| 50. | BP | 3 | cell cycle phase transition | 5.05e-10 | 1.47e-6 | 11 | 568/42493 genes: 1.34% |