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Disease Drug-Induced Liver Injury

These diseases have comparable sets of interacting chemicals and genes to Drug-Induced Liver Injury.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.24072 0.24072 376
Kidney Diseases 0.22409 0.22409 333
Acute Kidney Injury 0.19556 0.19556 273
Cholestasis 0.18129 0.18129 217
Drug-Related Side Effects and Adverse Reactions 0.17716 0.17716 256
Inflammation 0.16678 0.16678 249
Hepatomegaly 0.15798 0.15798 200
Weight Loss 0.15525 0.15525 204
Nausea 0.15524 0.15524 222
Liver Diseases 0.15485 0.15485 190
Fever 0.15065 0.15065 196
Headache 0.14971 0.14971 206
Edema 0.14566 0.14566 215
Hypertension 0.14361 0.14361 246
Seizures 0.14345 0.14345 278
Renal Insufficiency 0.14297 0.14297 185
Heart Diseases 0.14099 0.14099 183
Vomiting 0.1394 0.1394 196
Hepatitis 0.13936 0.13936 165
Jaundice 0.1382 0.1382 161
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Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.21446 0.21446 270
Acute Kidney Injury 0.20804 0.20804 233
Kidney Diseases 0.20548 0.20548 240
Cholestasis 0.19813 0.19813 191
Nausea 0.17155 0.17155 205
Drug-Related Side Effects and Adverse Reactions 0.16811 0.16811 194
Hepatomegaly 0.16747 0.16747 173
Headache 0.16579 0.16579 190
Jaundice 0.16578 0.16578 156
Liver Diseases 0.16191 0.16191 159
Hepatitis 0.16092 0.16092 154
Renal Insufficiency 0.15509 0.15509 163
Vomiting 0.15304 0.15304 176
Fever 0.1523 0.1523 159
Seizures 0.15077 0.15077 215
Weight Loss 0.14669 0.14669 153
Stevens-Johnson Syndrome 0.1368 0.1368 142
Drug Hypersensitivity 0.13503 0.13503 138
Hypertension 0.13366 0.13366 162
Diarrhea 0.12861 0.12861 138
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Via therapeutic chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.22646 0.22646 101
Kidney Diseases 0.18162 0.18162 83
Inflammation 0.13298 0.13298 75
Weight Loss 0.11685 0.11685 43
Acute Kidney Injury 0.11568 0.11568 45
Fatty Liver 0.11304 0.11304 39
Drug-Related Side Effects and Adverse Reactions 0.11192 0.11192 46
Heart Diseases 0.1084 0.1084 40
Edema 0.10317 0.10317 52
Liver Cirrhosis, Experimental 0.1027 0.1027 38
Proteinuria 0.09877 0.09877 40
Myocardial Infarction 0.09862 0.09862 43
Liver Cirrhosis 0.09593 0.09593 33
Cardiomyopathies 0.09259 0.09259 35
Carcinoma, Hepatocellular 0.08661 0.08661 33
Insulin Resistance 0.08356 0.08356 31
Hemorrhage 0.0831 0.0831 30
Liver Diseases 0.08157 0.08157 27
Neoplasms 0.08135 0.08135 41
Hypertension 0.07959 0.07959 55
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Via gene associations

Similarity Index Common
Interacting
Genes
Cholestasis 0.10611 0.10611 33
Liver Cirrhosis 0.09003 0.09003 28
Necrosis 0.08333 0.08333 23
Drug-Related Side Effects and Adverse Reactions 0.07829 0.07829 22
Fatty Liver 0.07333 0.07333 22
Acute Kidney Injury 0.07292 0.07292 21
Hypertension 0.06965 0.06965 28
Inflammation 0.06414 0.06414 22
Hypersensitivity 0.0625 0.0625 18
Neoplasm Metastasis 0.06188 0.06188 25
Pulmonary Fibrosis 0.06028 0.06028 17
Myocardial Reperfusion Injury 0.06013 0.06013 19
Liver Cirrhosis, Experimental 0.05998 0.05998 61
Lung Neoplasms 0.05841 0.05841 25
Reperfusion Injury 0.05806 0.05806 18
Arthritis, Rheumatoid 0.05612 0.05612 22
Heart Failure 0.0559 0.0559 18
Neoplasm Invasiveness 0.05464 0.05464 20
Kidney Diseases 0.05449 0.05449 17
Brain Ischemia 0.05245 0.05245 15
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Via marker/mechanism gene associations

Similarity Index Common
Interacting
Genes
Cholestasis 0.1 0.1 29
Liver Cirrhosis 0.07986 0.07986 23
Fatty Liver 0.07246 0.07246 20
Drug-Related Side Effects and Adverse Reactions 0.07115 0.07115 18
Necrosis 0.06827 0.06827 17
Hypersensitivity 0.06343 0.06343 17
Hypertension 0.05867 0.05867 22
Acute Kidney Injury 0.05747 0.05747 15
Lung Neoplasms 0.05486 0.05486 22
Liver Cirrhosis, Experimental 0.05199 0.05199 51
Myocardial Reperfusion Injury 0.05102 0.05102 15
Arthritis, Rheumatoid 0.0508 0.0508 19
Neoplasm Metastasis 0.0504 0.0504 19
Pneumonia 0.05 0.05 13
Inflammation 0.04918 0.04918 15
Liver Diseases 0.04779 0.04779 13
Kidney Diseases 0.0453 0.0453 13
Diabetes Mellitus, Experimental 0.04473 0.04473 14
Reperfusion Injury 0.04255 0.04255 12
Pulmonary Fibrosis 0.04231 0.04231 11
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Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Liver Diseases 0.10714 0.10714 3
Liver Neoplasms 0.09091 0.09091 3
Hypertension 0.08333 0.08333 4
Vascular System Injuries 0.08 0.08 2
Liver Cirrhosis, Experimental 0.07843 0.07843 4
Soft Tissue Neoplasms 0.07692 0.07692 2
Hyperplasia 0.07407 0.07407 2
Cholestasis 0.07143 0.07143 2
Weight Loss 0.07143 0.07143 2
Carcinoma, Transitional Cell 0.06897 0.06897 2
Pulmonary Edema 0.06897 0.06897 2
Colitis 0.06667 0.06667 2
Urinary Bladder Neoplasms 0.06667 0.06667 2
Pulmonary Fibrosis 0.06452 0.06452 2
Fibrosis 0.0625 0.0625 2
Amnesia 0.06061 0.06061 2
Heart Failure 0.06061 0.06061 2
Colonic Neoplasms 0.05882 0.05882 2
Kidney Diseases 0.05882 0.05882 2
Drug-Related Side Effects and Adverse Reactions 0.05714 0.05714 2
Insulin Resistance 0.05714 0.05714 2
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