| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | TNF | 768 | 10 |
| 2. | CYP1A1 | 756 | 22 |
| 3. | MAPK1 | 686 | 14 |
| 4. | MAPK3 | 677 | 12 |
| 5. | CASP3 | 630 | 12 |
| 6. | ESR1 | 562 | 12 |
| 7. | AHR | 493 | 12 |
| 8. | ESR2 | 441 | 7 |
| 9. | IL1B | 426 | 6 |
| 10. | NOS2 | 398 | 6 |
| 11. | PTGS2 | 392 | 7 |
| 12. | BCL2 | 346 | 6 |
| 13. | HMOX1 | 345 | 8 |
| 14. | IL6 | 331 | 6 |
| 15. | BAX | 280 | 8 |
| 16. | CAT | 252 | 11 |
| 17. | AKT1 | 250 | 7 |
| 18. | RELA | 241 | 6 |
| 19. | NFE2L2 | 234 | 7 |
| 20. | CASP9 | 218 | 7 |
| 21. | TP53 | 213 | 4 |
| 22. | PARP1 | 208 | 5 |
| 23. | CYP1A2 | 206 | 8 |
| 24. | CDKN1A | 192 | 4 |
| 25. | CYP1B1 | 186 | 8 |
| 26. | MMP9 | 176 | 4 |
| 27. | IFNG | 164 | 4 |
| 28. | VEGFA | 164 | 6 |
| 29. | CXCL8 | 157 | 5 |
| 30. | FOS | 138 | 4 |
| 31. | NFKBIA | 138 | 6 |
| 32. | CCND1 | 133 | 4 |
| 33. | HIF1A | 133 | 6 |
| 34. | CCL2 | 130 | 6 |
| 35. | INS1 | 124 | 4 |
| 36. | TGFB1 | 123 | 4 |
| 37. | JUN | 122 | 4 |
| 38. | NQO1 | 116 | 5 |
| 39. | CASP8 | 113 | 5 |
| 40. | SOD2 | 110 | 7 |
| 41. | ABCC1 | 107 | 4 |
| 42. | EGF | 104 | 5 |
| 43. | AR | 101 | 3 |
| 44. | TNFSF10 | 99 | 3 |
| 45. | AGT | 96 | 3 |
| 46. | STAT3 | 93 | 4 |
| 47. | BCL2L1 | 91 | 4 |
| 48. | PPARG | 91 | 5 |
| 49. | MMP2 | 88 | 4 |
| 50. | CYP3A4 | 86 | 3 |