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Illuminating how chemicals affect human health.
RotenoneThese GO terms are enriched significantly among genes that interact with Rotenone or its descendants. We show only terms with a corrected p-value <0.01.
| Ontology | Highest GO Level | GO Term | P-value | Corrected P-value | Annotated Genes | Genome Frequency | |
|---|---|---|---|---|---|---|---|
| 1. | BP | 1 | cellular process | 0 | 0 | 949 | 14530/42493 genes: 34.19% |
| 2. | BP | 1 | single-organism process | 0 | 0 | 888 | 12581/42493 genes: 29.61% |
| 3. | CC | 1 | cell | 0 | 0 | 968 | 15678/42493 genes: 36.90% |
| 4. | CC | 1 | cell part | 0 | 0 | 966 | 15648/42493 genes: 36.82% |
| 5. | CC | 2 | intracellular | 0 | 0 | 923 | 13596/42493 genes: 32.00% |
| 6. | CC | 2 | intracellular part | 0 | 0 | 912 | 13333/42493 genes: 31.38% |
| 7. | BP | 2 | single-organism cellular process | 1.21e-320 | 1.40e-316 | 815 | 10200/42493 genes: 24.00% |
| 8. | CC | 3 | cytoplasm | 1.70e-313 | 1.97e-309 | 820 | 10590/42493 genes: 24.92% |
| 9. | CC | 1 | organelle | 1.50e-309 | 1.73e-305 | 871 | 12643/42493 genes: 29.75% |
| 10. | CC | 2 | membrane-bounded organelle | 7.80e-298 | 9.00e-294 | 837 | 11713/42493 genes: 27.56% |
| 11. | MF | 1 | binding | 1.02e-289 | 1.18e-285 | 887 | 14042/42493 genes: 33.05% |
| 12. | CC | 3 | cytoplasmic part | 2.90e-289 | 3.35e-285 | 748 | 8966/42493 genes: 21.10% |
| 13. | BP | 1 | metabolic process | 1.48e-285 | 1.71e-281 | 803 | 10886/42493 genes: 25.62% |
| 14. | CC | 2 | intracellular organelle | 9.81e-279 | 1.13e-274 | 817 | 11621/42493 genes: 27.35% |
| 15. | BP | 2 | cellular metabolic process | 5.53e-277 | 6.38e-273 | 770 | 10040/42493 genes: 23.63% |
| 16. | MF | 2 | protein binding | 1.64e-276 | 1.90e-272 | 789 | 10697/42493 genes: 25.17% |
| 17. | BP | 2 | organic substance metabolic process | 4.64e-271 | 5.35e-267 | 775 | 10399/42493 genes: 24.47% |
| 18. | BP | 2 | nitrogen compound metabolic process | 1.14e-246 | 1.31e-242 | 723 | 9505/42493 genes: 22.37% |
| 19. | BP | 2 | primary metabolic process | 5.51e-246 | 6.35e-242 | 738 | 10009/42493 genes: 23.55% |
| 20. | BP | 1 | response to stimulus | 6.47e-246 | 7.46e-242 | 679 | 8202/42493 genes: 19.30% |
| 21. | CC | 1 | organelle part | 3.86e-243 | 4.46e-239 | 692 | 8668/42493 genes: 20.40% |
| 22. | CC | 2 | intracellular organelle part | 2.50e-240 | 2.88e-236 | 682 | 8460/42493 genes: 19.91% |
| 23. | CC | 3 | intracellular membrane-bounded organelle | 1.34e-238 | 1.55e-234 | 729 | 9968/42493 genes: 23.46% |
| 24. | BP | 1 | biological regulation | 6.88e-238 | 7.94e-234 | 753 | 10793/42493 genes: 25.40% |
| 25. | BP | 3 | organonitrogen compound metabolic process | 1.22e-228 | 1.41e-224 | 594 | 6405/42493 genes: 15.07% |
| 26. | BP | 2 | cellular response to stimulus | 3.20e-228 | 3.69e-224 | 592 | 6366/42493 genes: 14.98% |
| 27. | BP | 1 | regulation of biological process | 2.09e-225 | 2.42e-221 | 723 | 10235/42493 genes: 24.09% |
| 28. | BP | 2 | regulation of cellular process | 5.29e-223 | 6.10e-219 | 700 | 9578/42493 genes: 22.54% |
| 29. | BP | 2 | response to stress | 2.51e-216 | 2.90e-212 | 452 | 3564/42493 genes: 8.39% |
| 30. | BP | 2 | response to chemical | 4.38e-206 | 5.05e-202 | 466 | 4045/42493 genes: 9.52% |
| 31. | BP | 2 | single-organism metabolic process | 1.14e-198 | 1.31e-194 | 462 | 4124/42493 genes: 9.71% |
| 32. | BP | 2 | cellular component organization | 1.58e-196 | 1.82e-192 | 523 | 5531/42493 genes: 13.02% |
| 33. | BP | 1 | cellular component organization or biogenesis | 3.12e-195 | 3.59e-191 | 529 | 5710/42493 genes: 13.44% |
| 34. | BP | 1 | positive regulation of biological process | 3.27e-193 | 3.77e-189 | 508 | 5266/42493 genes: 12.39% |
| 35. | BP | 2 | cell communication | 1.28e-192 | 1.48e-188 | 522 | 5613/42493 genes: 13.21% |
| 36. | BP | 2 | single organism signaling | 9.31e-191 | 1.07e-186 | 519 | 5592/42493 genes: 13.16% |
| 37. | BP | 1 | signaling | 2.15e-190 | 2.48e-186 | 519 | 5602/42493 genes: 13.18% |
| 38. | BP | 2 | positive regulation of cellular process | 8.26e-187 | 9.53e-183 | 472 | 4614/42493 genes: 10.86% |
| 39. | BP | 2 | single-multicellular organism process | 1.22e-185 | 1.40e-181 | 529 | 5981/42493 genes: 14.08% |
| 40. | BP | 3 | response to organic substance | 1.34e-185 | 1.54e-181 | 377 | 2767/42493 genes: 6.51% |
| 41. | BP | 3 | cellular response to chemical stimulus | 9.35e-185 | 1.08e-180 | 370 | 2661/42493 genes: 6.26% |
| 42. | BP | 3 | macromolecule metabolic process | 8.61e-184 | 9.93e-180 | 630 | 8819/42493 genes: 20.75% |
| 43. | BP | 3 | cellular response to stress | 2.73e-180 | 3.15e-176 | 310 | 1786/42493 genes: 4.20% |
| 44. | BP | 3 | cellular nitrogen compound metabolic process | 5.88e-178 | 6.78e-174 | 533 | 6312/42493 genes: 14.85% |
| 45. | BP | 1 | developmental process | 7.00e-178 | 8.07e-174 | 507 | 5664/42493 genes: 13.33% |
| 46. | BP | 2 | single-organism developmental process | 4.15e-177 | 4.79e-173 | 503 | 5589/42493 genes: 13.15% |
| 47. | BP | 3 | cellular macromolecule metabolic process | 1.52e-175 | 1.75e-171 | 596 | 8113/42493 genes: 19.09% |
| 48. | BP | 2 | regulation of metabolic process | 1.32e-173 | 1.52e-169 | 522 | 6165/42493 genes: 14.51% |
| 49. | BP | 1 | negative regulation of biological process | 2.11e-173 | 2.44e-169 | 464 | 4777/42493 genes: 11.24% |
| 50. | BP | 2 | signal transduction | 4.19e-173 | 4.84e-169 | 481 | 5177/42493 genes: 12.18% |