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Disease Occupational Diseases

These chemicals are associated with Occupational Diseases or its descendants. A chemical has either a curated association to the disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated gene interaction.

1–50 of 15,166 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Asbestos Asbestosis M
10 genes: CFD | GSTT1 | NLRP3 | NOS2 | PRDX1 | PRDX2 | SERPINA1 | SPP1 | TNF | TPM4 		43.58 12
Has associated exposure references.
2. Asbestos, Amphibole Asbestosis M
7 genes: DDIT3 | HSPA5 | NLRP3 | NOS2 | PRDX1 | PRDX2 | TNF 		31.12 7
3. Asbestos, Serpentine Asbestosis M
7 genes: ATF6 | DDIT3 | HSPA5 | NLRP3 | NOS2 | SPP1 | TNF 		23.05 10
Has associated exposure references.
4. Disinfectants Asthma, Occupational M
3 genes: PLA2G4A | PRKCA | PRKD1 		21.53 1
Has associated exposure references.
5. hydroquinone Occupational Diseases M
6 genes: ALB | CYP1A1 | CYP2D6 | MPO | NQO1 | TIMP2 		16.61 8
6. Asbestos, Crocidolite Asbestosis M
7 genes: ATF6 | DDIT3 | HSPA5 | NLRP3 | NOS2 | SPP1 | TNF 		16.47 8
Has associated exposure references.
7. Silicon Dioxide Silicosis M
8 genes: AHR | ARG1 | CCL2 | CPM | IL1B | NOS2 | PDZRN4 | RETNLA 		16.43 13
Has associated exposure references.
8. Glutathione Occupational Diseases M
7 genes: ALB | CYP1A1 | CYP2D6 | MPO | NQO1 | PON1 | TGFB1 		15.65 8
9. Beryllium Berylliosis M
2 genes: HLA-DPB1 | TNF 		12.57 13
Has associated exposure references.
10. Reactive Oxygen Species Asbestosis M
4 genes: ATF6 | DDIT3 | NOS2 | TNF 		12.18 4
11. Polycyclic Hydrocarbons, Aromatic Occupational Diseases M
4 genes: CYP1A1 | NQO1 | PON1 | XRCC1 		11.39 8
12. Plant Preparations Asthma, Occupational M
4 genes: PTGS1 | PTGS2 | TGFB1 | TNF 		11.37 2
13. Phenol Occupational Diseases M
4 genes: ALB | CYP1A1 | MPO | NQO1 		10.96 7
14. Benzene Occupational Diseases M
7 genes: ALB | CYP1A1 | CYP2D6 | ERCC2 | MPO | NQO1 | XRCC1 		10.19 20
15. Silicon Dioxide Asthma, Occupational M
8 genes: CDH17 | PLA2G4A | PRKCA | PRKD1 | PTGS1 | PTGS2 | TGFB1 | TNF 		8.95 4
Has associated exposure references.
16. Lindane Occupational Diseases M
5 genes: ALB | CYP1A1 | CYP2D6 | MPO | TGFB1 		8.87 7
17. Triiodothyronine Occupational Diseases M
5 genes: ALB | CYP1A1 | MPO | TGFB1 | TIMP2 		8.84 5
18. Chromium Occupational Diseases M
4 genes: ALB | CYP1A1 | NQO1 | TGFB1 		8.76 8
19. Manganese Occupational Diseases M
5 genes: CYP2D6 | ERCC2 | NQO1 | PON1 | TGFB1 		8.72 10
20. Cobalt Occupational Diseases M
4 genes: ALB | CYP1A1 | NQO1 | TGFB1 		8.60 9
21. Iron Asbestosis M
3 genes: DDIT3 | NOS2 | TNF 		7.80 4
22. Lead Occupational Diseases M
6 genes: ALB | CYP1A1 | ERCC2 | NQO1 | PON1 | XRCC1 		7.40 10
23. Toluene 2,4-Diisocyanate Occupational Diseases M
3 genes: ALB | CYP1A1 | TGFB1 		7.39 10
24. Flame Retardants Occupational Diseases M
3 genes: ALB | CYP1A1 | NQO1 		6.56 8
25. Toluene 2,4-Diisocyanate Asthma, Occupational M
2 genes: TGFB1 | TNF 		6.41 2
26. Chromium Asthma, Occupational M
2 genes: TGFB1 | TNF 		5.73 2
27. Vinyl Chloride Occupational Diseases M
2 genes: ERCC2 | XRCC1 		5.67 3
28. Hydrochloric Acid Occupational Diseases M
2 genes: ALB | MPO 		5.49 3
29. Metoclopramide Occupational Diseases M
2 genes: CYP2D6 | MPO 		5.48 3
30. Methamphetamine Occupational Diseases M
5 genes: CYP2D6 | NQO1 | TGFB1 | TIMP2 | XRCC1 		4.54 8
31. muconic acid Occupational Diseases M   1 gene: NQO1 4.39 5
32. mancozeb Dermatitis, Occupational M   1 gene: ALDH2 4.17 3
33. Sarin Persian Gulf Syndrome M   1 gene: PON1 4.13 2
34. Trinitrotoluene Occupational Diseases M
2 genes: CYP1A1 | NQO1 		4.08 8
35. Organophosphates Agricultural Workers' Diseases M   1 gene: PON1 4.04 5
Has associated exposure references.
36. Platinum Asthma, Occupational M   1 gene: PTGS2 4.03 2
37. Vehicle Emissions Pneumoconiosis M
6 genes: CDH23 | HS3ST6 | IL27RA | IL4 | OVGP1 | TMPRSS3 		4.03 3
Has associated exposure references.
38. Isocyanates Asthma, Occupational M   1 gene: TNF 4.00 2
39. Toluene Occupational Diseases M
3 genes: ALB | CYP1A1 | NQO1 		3.99 7
Has associated exposure references.
40. Vinyl Chloride Dermatitis, Occupational M   1 gene: ALDH2 3.98 2
41. 4,4'-diphenylmethane diisocyanate Occupational Diseases M   1 gene: ALB 3.92 3
42. Trichloroethylene Dermatitis, Occupational M
2 genes: NAT1 | NAT2 		3.86 7
43. Carbon Tetrachloride Agricultural Workers' Diseases M   1 gene: PON1 3.78 4
Has associated exposure references.
44. Arsenic Occupational Diseases M
8 genes: CYP1A1 | ERCC2 | MPO | NQO1 | PON1 | TGFB1 | TIMP2 | XRCC1 		3.67 10
45. Insecticides Agricultural Workers' Diseases M   1 gene: PON1 3.65 4
Has associated exposure references.
46. Maneb Dermatitis, Occupational M   1 gene: ALDH2 3.65 2
47. Cotinine Occupational Diseases M   1 gene: CYP1A1 3.57 2
48. Chlorpyrifos Persian Gulf Syndrome M   1 gene: PON1 3.50 3
49. Carbon Disulfide Occupational Diseases M   1 gene: NQO1 3.49 5
50. catechol Occupational Diseases M   1 gene: NQO1 3.46 5
1–50 of 15,166 results.
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