Hydrocarbons, Chlorinated - Diseases

These diseases are associated with Hydrocarbons, Chlorinated or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 44,075 results.

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	Chemical	Disease	Direct Evidence	Inference Network	Inference Score	References
1.	Carbon Tetrachloride	Liver Cirrhosis, Experimental	M	483 genes: AADAC \| AADAT \| ABAT \| ABCA8A \| ABCB1 \| ABCB1A \| ABCC2 \| ABCG1 \| ABCG5 \| ACHE \| ACKR3 \| ACOT9 \| ACOX2 \| ACSL1 \| ACTA2 \| ACTN1 \| ADA \| ADD3 \| ADGRE1 \| ADH4 \| ADHFE1 \| ADIPOQ \| ADM \| ADORA2A \| ADORA3 \| ADRA1B \| AFP \| AGFG1 \| AGT \| AGTR1A \| AIF1 \| ALB \| ALDH1A1 \| ALDH1A7 \| ALDH1B1 \| ALDH1L1 \| ALDH1L2 \| ALDH2 \| AMACR \| ANGPTL3 \| ANXA2 \| ANXA3 \| ANXA4 \| ANXA5 \| AP1S2 \| APOA4 \| APOBEC1 \| APP \| ARHGDIB \| ARPC1B \| ARRB2 \| ASNS \| ATF3 \| AXL \| BBOX1 \| BCL2A1D \| BDH1 \| BGN \| BICD2 \| BMP7 \| C1QA \| C1QB \| C1QC \| CA3 \| CAPG \| CAR3 \| CAR5A \| CASP1 \| CASP12 \| CAV1 \| CCL2 \| CCL5 \| CCL6 \| CCNA2 \| CCNB2 \| CCNG1 \| CD163 \| CD276 \| CD36 \| CD48 \| CD53 \| CD5L \| CD63 \| CD68 \| CD74 \| CDK1 \| CDKN1A \| CDKN3 \| CDO1 \| CEBPD \| CELA1 \| CERK \| CFP \| CHSY1 \| CKLF \| CLEC4A3 \| CLEC4F \| CMTM3 \| CNPY4 \| COL1A1 \| COL1A2 \| COL3A1 \| COL4A1 \| COL4A2 \| COL5A1 \| COL5A2 \| COLEC12 \| COTL1 \| CPQ \| CPS1 \| CRTAP \| CRY1 \| CRYAB \| CSAD \| CSF1R \| CSF3 \| CTGF \| CTLA2A \| CTSS \| CXADR \| CXCL1 \| CXCL10 \| CXCL12 \| CXCL13 \| CXCL16 \| CYBA \| CYBB \| CYGB \| CYP1A2 \| CYP26A1 \| CYP2A2 \| CYP2C \| CYP2C11 \| CYP2D4 \| CYP3A11 \| CYP3A13 \| DCXR \| DDC \| DHRS3 \| DHTKD1 \| DIO1 \| DOCK10 \| DPYS \| DRAM1 \| DUSP6 \| DYSF \| ECT2 \| EDN1 \| EGF \| EIF4E3 \| ELA1 \| ENC1 \| ENPEP \| ENPP2 \| EPB41L2 \| ERAP1 \| EZR \| F2R \| FABP7 \| FAHD1 \| FAM89A \| FBN1 \| FCER1G \| FGF2 \| FGL2 \| FHL2 \| FKBP1A \| FLI1 \| FMO1 \| FOLR2 \| FOS \| FRY \| FSTL1 \| FTCD \| G0S2 \| G6PC \| GBP2 \| GBP4 \| GC \| GCAT \| GCHFR \| GCK \| GGH \| GHR \| GJA1 \| GJA4 \| GK \| GLIPR1 \| GLS2 \| GNA14 \| GNAI2 \| GNGT2 \| GOT1 \| GPAM \| GPNMB \| GPT \| GRN \| GSN \| GSTA2 \| GSTA3 \| GSTM1 \| GULO \| GULP1 \| HAL \| HCK \| HELLS \| HFE2 \| HGF \| HMGCR \| HMOX1 \| HPSE \| HSD17B2 \| HSD17B6 \| HYKK \| ICAM2 \| ID2 \| IFI204 \| IFI27L2B \| IFNA1 \| IFNG \| IFNGR1 \| IFRD1 \| IGF1 \| IGF2R \| IGFALS \| IGFBP1 \| IGFBP2 \| IGFBP3 \| IGFBP7 \| IGSF6 \| IL10 \| IL18 \| IL18BP \| IL1B \| IL2RB \| IL2RG \| ILK \| INHBC \| INHBE \| INMT \| IQGAP1 \| IRF8 \| ITGB1 \| ITGB2 \| ITGB6 \| IVD \| IYD \| JAK2 \| KCNJ8 \| KLF6 \| KMO \| KNG1 \| KRT18 \| KRT19 \| KRT8 \| KTN1 \| KYNU \| L3HYPDH \| LAPTM5 \| LBH \| LBP \| LCN2 \| LCP1 \| LDHB \| LEP \| LGALS1 \| LGALS3 \| LGALSL \| LGMN \| LIN7A \| LMO2 \| LOX \| LOXL2 \| LPL \| LPXN \| LRAT \| LTB \| LTBP1 \| LUM \| LY86 \| LY96 \| MAGEE1 \| MALAT1 \| MAP1LC3A \| METRNL \| MGAT5 \| MGMT \| MGP \| MKI67 \| MME \| MMP1 \| MMP13 \| MMP2 \| MMP8 \| MMP9 \| MSN \| MT1A \| MVP \| MYC \| MYL9 \| MYO1C \| MYO1F \| NAP1L5 \| NAT8 \| NDRG1 \| NDRG2 \| NEK6 \| NFE2L2 \| NFKBIA \| NFKBIE \| NFKBIZ \| NID1 \| NID2 \| NLRC5 \| NMI \| NOS2 \| NOS3 \| NOX4 \| NPAS2 \| NQO2 \| NR0B2 \| NREP \| NRROS \| NT5E \| NUPR1 \| OAT \| OLFML2B \| OLFML3 \| OSGIN1 \| OSM \| OTC \| PC \| PCK1 \| PCK2 \| PDGFA \| PDGFRA \| PDGFRB \| PFKP \| PKLR \| PLA2G12A \| PLA2G4A \| PLAC8 \| PLAT \| PLAU \| PLEK \| PLG \| PLIN2 \| PLIN3 \| PLOD2 \| PLPP2 \| PLSCR1 \| PLSCR2 \| PLTP \| PMEPA1 \| POMC \| PPAP2A \| PPP1R3B \| PQLC3 \| PRKCB \| PRLR \| PROCR \| PSMB8 \| PTAFR \| PTGER2 \| PTGS1 \| PTGS2 \| PTN \| PTPN1 \| PTPRC \| PTPRD \| PTPRO \| PTRH1 \| PXDN \| RAB30 \| RAB32 \| RAB8B \| RABGAP1L \| RAMP1 \| RBL2 \| RCN1 \| RDH10 \| RDH13 \| RECK \| REEP5 \| RELA \| RGN \| RGS10 \| RGS2 \| RGS3 \| RGS5 \| RNASE4 \| RNASEL \| RSRP1 \| RTN4 \| S100A10 \| S100A11 \| S100A6 \| S100A9 \| SCD2 \| SDR42E1 \| SDS \| SELENBP2 \| SELENOM \| SEMA6D \| SERPINA3K \| SERPINA3M \| SERPINA6 \| SERPINA7 \| SERPINB9 \| SERPINH1 \| SH3BGRL3 \| SHCBP1 \| SIRT1 \| SLC10A1 \| SLC15A3 \| SLC17A1 \| SLC17A2 \| SLC19A2 \| SLC20A1 \| SLC22A8 \| SLC25A30 \| SLC25A4 \| SLC37A4 \| SLC39A6 \| SLC44A2 \| SLC46A1 \| SLC4A4 \| SLC7A1 \| SLFN2 \| SMAD2 \| SMAD4 \| SMC2 \| SMOC2 \| SOX4 \| SPARC \| SPSB4 \| SRD5A1 \| SREBF1 \| SRGN \| SRR \| STEAP4 \| TAP2 \| TCF4 \| TES \| TFEC \| TFPI2 \| TGFB1 \| TGFB3 \| TGFBR2 \| THBD \| TIMP1 \| TIMP2 \| TLR4 \| TM6SF1 \| TMBIM1 \| TMEM106A \| TMEM165 \| TMEM2 \| TMEM43 \| TNF \| TNFAIP8 \| TNFRSF12A \| TPM1 \| TPM3 \| TRF \| TRIB3 \| TRIM59 \| TSC22D1 \| TSPO \| TTC36 \| TUBB6 \| TUSC3 \| TYROBP \| UGCG \| UGT2B \| VASP \| VEGFA \| VIM \| VIPR1 \| WIPF1 \| YBX1 \| ZDHHC2 \| ZEB2	780.85	185
2.	Carbon Tetrachloride	Carcinoma, Hepatocellular	M	134 genes: ABCB1 \| ABCB4 \| ACACA \| ACE \| ACLY \| ACOX1 \| ACSL4 \| ACTB \| ADAMTS1 \| AFP \| ANXA4 \| APCS \| APEX1 \| APOA1 \| BCL2L1 \| BIRC5 \| BTG2 \| C9 \| CASP8 \| CBR1 \| CCL3 \| CCND1 \| CCNE1 \| CCR1 \| CD276 \| CDH13 \| CDK14 \| CDK4 \| CDKN1B \| CDKN2A \| CEBPA \| CEBPB \| CEBPD \| COMT \| CTNNB1 \| CTSD \| CXCL12 \| CYP1A1 \| CYP2E1 \| DPYD \| E2F1 \| EGF \| EGFR \| EPHX1 \| ESR1 \| F2 \| FASN \| FOS \| FOXM1 \| FST \| GAPDH \| GDF2 \| GJB1 \| GLUL \| GNMT \| GPC3 \| GSTM1 \| GSTP1 \| HGF \| HGFAC \| HHIP \| HMGCR \| HRAS \| HSD3B2 \| HSPA5 \| HSPB1 \| HTATIP2 \| IFNA1 \| IGF1R \| IGF2 \| IGF2R \| IL6 \| IQGAP1 \| IRS1 \| IRS2 \| ITIH3 \| JUN \| KRAS \| MAT1A \| MBTPS2 \| ME1 \| MECP2 \| MET \| MLXIPL \| MMP2 \| MMP9 \| MPO \| MT1A \| MYC \| NFE2L2 \| NFKBIA \| NME1 \| NR0B2 \| NR1H2 \| NR1H4 \| PCK1 \| PDGFB \| PDIA3 \| PGD \| PKM \| PPARG \| PRDX2 \| PRDX6 \| PTEN \| PTGS2 \| PYGL \| RAC1 \| RB1 \| RPS6 \| RRM1 \| RRM2 \| SCD \| SERPINA1 \| SLC2A1 \| SLC2A2 \| SOCS3 \| SOD2 \| SREBF1 \| STAT1 \| TALDO1 \| TFPI2 \| TGFA \| TGFB1 \| TLR4 \| TMEM70 \| TNF \| TNFSF10 \| TP53 \| TRP53 \| TST \| TYMS \| USP2 \| VASN \| VCAM1	127.67	111
3.	DDT	Prostatic Neoplasms	M	56 genes: ADRB2 \| AHR \| AR \| BCL2 \| CCND1 \| CCND2 \| CDH1 \| CDKN1A \| CREBBP \| CTNNB1 \| CTSD \| CXCL12 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| DNMT1 \| DNMT3B \| EGF \| EGR1 \| EPHX1 \| ERBB2 \| ESR1 \| ESR2 \| FOLH1 \| GGT1 \| GJA1 \| GSK3B \| HSD17B1 \| HSD3B1 \| HSP90AB1 \| IGF1 \| IL2 \| KLK3 \| LEP \| LPL \| MAPK3 \| MDM2 \| MIR21 \| MT2A \| MYC \| NR3C1 \| OGG1 \| PENK \| PODXL \| PTGS2 \| SHBG \| SLC12A2 \| SOD2 \| STAT3 \| TGFB1 \| TP53 \| TYMS \| VEGFA \| VIM	99.45	113
4.	Polychlorinated Biphenyls	Breast Neoplasms	M	75 genes: ACHE \| AFP \| AGR2 \| AHR \| AKAP12 \| AKT1 \| ANGPTL4 \| APOBEC3B \| AR \| ARAF \| AREG \| AURKA \| BCHE \| BIRC5 \| CAT \| CDKN1B \| CDKN2A \| CENPF \| CHEK1 \| CLDN4 \| COMT \| CXCL12 \| CXCL2 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2B1 \| CYP3A4 \| DNMT1 \| DNMT3A \| DNMT3B \| EIF2S2 \| EP300 \| ESR1 \| ESR2 \| ETS2 \| FOS \| FOXQ1 \| GPI \| GPNMB \| H2AFX \| HEY1 \| HMOX1 \| HP \| IFNG \| IL6 \| JUN \| KRAS \| MDM4 \| MKI67 \| MMP3 \| NCOA3 \| NQO1 \| PPARGC1B \| PRC1 \| PTGS2 \| RAD51 \| RAD51C \| RAD54L \| RAF1 \| RARA \| RPS8 \| SOD2 \| SPP1 \| STC2 \| STMN1 \| TGM2 \| THBS1 \| THEMIS2 \| TNF \| TOP2A \| TP53 \| TYMS \| UBE2C	96.75	105
5.	Dichlorodiphenyl Dichloroethylene	Prostatic Neoplasms	M	53 genes: AHR \| AR \| ATF3 \| BAX \| BCL2 \| BRCA1 \| CASP9 \| CCND1 \| CLU \| CREBBP \| CTNNB1 \| CTSD \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| EGF \| EGFR \| ERBB2 \| ERBB3 \| ESR1 \| ESR2 \| FASLG \| FGFR4 \| FOLH1 \| FOXC1 \| GJA1 \| GSK3B \| HBG1 \| HNRNPH1 \| IGF1 \| IL6 \| INS \| KLK3 \| LEP \| MAPK3 \| MSMB \| MT2A \| MYC \| NFE2L2 \| NOS3 \| NR3C1 \| PARP1 \| PTGS2 \| RUNX1 \| RXRA \| SHBG \| SRD5A2 \| STAT3 \| TGFB1 \| TP53 \| UGT2B17 \| VIM	95.64	106
6.	DDT	Breast Neoplasms	M	57 genes: ABCB1 \| ABCG2 \| AHR \| AR \| BCL2 \| CASP7 \| CAT \| CCND1 \| CDH1 \| CDKN2A \| CTNNB1 \| CXCL12 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2B1 \| CYP3A4 \| DDIT3 \| DNMT1 \| DNMT3A \| DNMT3B \| E2F1 \| EGF \| ENO1 \| ERBB2 \| ESR1 \| ESR2 \| FN1 \| FOS \| GPER1 \| IGF1 \| IL1B \| JUN \| KIT \| KRT18 \| KRT8 \| LEP \| MDM2 \| MIR342 \| MMP3 \| NOS2 \| NOTCH1 \| PGR \| PTGS1 \| PTGS2 \| RB1 \| RXRB \| SERPINB5 \| SOD2 \| SPP1 \| STAT3 \| TNF \| TP53 \| TRP53 \| TYMS \| VIM	92.59	131
7.	Dichlorodiphenyl Dichloroethylene	Breast Neoplasms	M	55 genes: ABCB1 \| ABCB1B \| ABCG2 \| AHR \| AR \| BAX \| BCL2 \| BRCA1 \| CADM1 \| CASP8 \| CAT \| CCND1 \| CTNNB1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2B1 \| CYP3A4 \| DDIT3 \| DPYD \| EGF \| EGFR \| ERBB2 \| ERBB3 \| ESR1 \| ESR2 \| FASN \| FOS \| GPX4 \| IFNG \| IGF1 \| IGF1R \| IL1B \| IL6 \| JUN \| KIT \| KRT18 \| LEP \| NFKBIA \| NOS2 \| NOS3 \| NOTCH2 \| NOTCH3 \| NOTCH4 \| NRCAM \| NRG1 \| PARP1 \| PGR \| PTGS2 \| RELA \| RXRB \| STAT3 \| TNF \| TP53 \| VIM	91.97	135
8.	Polychlorinated Biphenyls	Prostatic Neoplasms	M	67 genes: ACHE \| AGR2 \| AHR \| AKR1C3 \| AKT1 \| AR \| ATF3 \| AURKA \| CDK2AP2 \| CDKN1A \| CDKN1B \| CLU \| COMT \| CXCL12 \| CYP11B2 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| DNMT1 \| DNMT3B \| EGR1 \| EPHX1 \| ESR1 \| ESR2 \| EZR \| GADD45A \| GALNT3 \| GJA1 \| GREB1 \| GSK3B \| HMOX1 \| HSD3B2 \| HSP90AB1 \| ID3 \| IL10 \| IL2 \| IL6 \| JUP \| KEAP1 \| LIFR \| MAD1L1 \| MAPK3 \| MYC \| NCOA3 \| NFE2L2 \| NQO1 \| NR3C1 \| OLFM1 \| P4HB \| PON1 \| PRNP \| PSCA \| PTGS2 \| RAD23B \| SOD2 \| STMN1 \| SULT1A1 \| SULT1E1 \| SULT2A1 \| SULT2B1 \| TGFB1 \| TOP2A \| TP53 \| TRAF1 \| TYMS	90.29	100
9.	Carbon Tetrachloride	Lung Neoplasms	M	114 genes: ACE \| ACSM1 \| ACTB \| ADA \| AKT1 \| ANXA2 \| APOA1 \| APOC3 \| APOE \| BCL2L1 \| BIRC5 \| CASP8 \| CCND1 \| CCNG1 \| CDH13 \| CDKN1A \| CDKN1B \| CDKN2A \| CEACAM1 \| CES1F \| CHEK2 \| CLPTM1L \| CTGF \| CTNNB1 \| CXCL14 \| CYP1A2 \| CYP1B1 \| CYP2E1 \| DAB2IP \| DAPK1 \| DDR1 \| DNMT3A \| DPYD \| EFEMP1 \| EGFR \| EPHX1 \| ESR1 \| FAS \| FASLG \| FGF9 \| FGFR1 \| FGFR2 \| FHIT \| FOS \| FOXM1 \| GAST \| GC \| GJA1 \| GJB1 \| GPX1 \| GRB7 \| GSTM1 \| GSTP1 \| GSTT1 \| HES1 \| HMOX1 \| HRAS \| ID3 \| IFNG \| IL10 \| IL1B \| IL2 \| IL6 \| IRF1 \| JUN \| JUNB \| KRAS \| MAPK1 \| MAPK14 \| MAPK3 \| MCL1 \| MET \| MIR127 \| MIR155 \| MIR30A \| MIR31 \| MIR34C \| MIR370 \| MIR410 \| MMP1 \| MMP10 \| MPO \| MYC \| NOS2 \| NOTCH2 \| NPPA \| OGG1 \| PCNA \| PON1 \| PRDX1 \| PRDX6 \| PTEN \| PTGIS \| PTMA \| RAMP2 \| RARB \| ROBO1 \| SELENBP1 \| SERPINA1 \| SLC3A2 \| SPP1 \| TFRC \| TGFB1 \| TGFBR2 \| TLR4 \| TNF \| TP53 \| TRP53 \| TSHR \| TTR \| TYMS \| WNT5A \| WT1 \| XPC	86.03	134
10.	Carbon Tetrachloride	Liver Cirrhosis	M	79 genes: ABCB4 \| ACTA2 \| AGT \| ALAD \| ALB \| C1QB \| CCL2 \| CD14 \| CD9 \| CHRM3 \| CNR2 \| COL1A1 \| COL1A2 \| COL3A1 \| COL5A2 \| CTGF \| CTNNB1 \| CYBA \| CYP1A2 \| CYP27A1 \| CYP2R1 \| DHCR7 \| F2 \| F2R \| F3 \| FBN1 \| FGF2 \| FGF7 \| FGFR2 \| FLT1 \| GC \| HDAC2 \| HGF \| HSD11B2 \| IFNA1 \| IGFBP1 \| IGFBP2 \| IL6 \| JUND \| KRT18 \| KRT8 \| LGALS1 \| LGALS3BP \| LOX \| LUM \| MIR153 \| MIR215 \| MIR29C \| MIR302C \| MIR30B \| MIR30C-1 \| MIR30C2 \| MIR376C \| MIR503 \| MIR764 \| MMP2 \| NFE2L2 \| NPPA \| PCOLCE \| PLAU \| PLOD2 \| RGN \| SERPINA1 \| SERPINA6 \| SERPING1 \| SERPINH1 \| SLC17A2 \| SLC22A8 \| SMAD3 \| SPARC \| SPP1 \| STAT1 \| TGFB1 \| THBS1 \| TNFRSF1B \| TRPM7 \| VEGFA \| VIM \| VTN	83.16	97
11.	Dieldrin	Breast Neoplasms	M	83 genes: ABCB1 \| ABCC1 \| ABCG2 \| AHR \| AKT2 \| AR \| ARAF \| ATM \| AURKA \| BAG1 \| BAX \| BCL2 \| BIRC2 \| BIRC5 \| BRCA1 \| C1QBP \| CASP7 \| CASP8 \| CAT \| CCND1 \| CCNE1 \| CENPF \| CHEK2 \| COMT \| CUL5 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| DAP3 \| DDIT3 \| E2F1 \| EGFR \| ENO1 \| ERBB3 \| ESR1 \| ESR2 \| FGFR1 \| FOS \| FST \| GPX1 \| GPX4 \| HMMR \| HMOX1 \| IGF1 \| IL1B \| IL6 \| JAG1 \| JUN \| KDR \| KIT \| LSP1 \| MAP2K7 \| MDM2 \| MDM4 \| MED28 \| MKI67 \| MMP9 \| MRPL19 \| NOTCH1 \| NOTCH2 \| NSD2 \| PARP1 \| PDGFA \| PGR \| PRC1 \| RAF1 \| RARA \| RARB \| RB1 \| RGS2 \| RPS8 \| SLC2A2 \| SOD2 \| SRC \| TGM2 \| TNF \| TP53 \| TRP53 \| UBE2C \| VEGFB \| VEGFC \| WT1 \| WWOX	78.80	122
12.	Hexachlorobenzene	Breast Neoplasms	M	41 genes: AHR \| AKT1 \| AKT2 \| CASP8 \| CAT \| CCL20 \| CCND1 \| CCNE1 \| CD74 \| CDH1 \| CDKN1B \| CDKN2A \| COMT \| CXCR4 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2B1 \| EGFR \| ESR1 \| FN1 \| FOS \| GSTP1 \| HMOX1 \| HP \| IFNG \| IGF1R \| IL1B \| IL6 \| JUN \| KDR \| MAP3K1 \| MMP2 \| MMP9 \| NQO1 \| PTGS2 \| RXRB \| SOD2 \| SRC \| TFRC	76.18	78
13.	Dinitrochlorobenzene	Dermatitis, Allergic Contact	M	35 genes: ABCA6 \| BMP6 \| CALCRL \| CCR2 \| CD36 \| CIDEC \| CREM \| CTSC \| CXCL2 \| CYP1A1 \| EMB \| F13A1 \| FGL2 \| IFNG \| IL10 \| IL18 \| IL1A \| IL2 \| IL2RA \| IL4 \| IL5 \| IPCEF1 \| NAMPT \| NFE2L2 \| NINJ1 \| PHLDA1 \| PLAT \| RAB32 \| RGS1 \| SAT1 \| SLC2A3 \| SLC7A5 \| SPP1 \| TNF \| TNFAIP6	76.17	17
14.	Lindane	Prostatic Neoplasms	M	54 genes: ABCC4 \| ACHE \| AHR \| AR \| BAX \| BCL2 \| CALR \| CASP9 \| CDKN1A \| CLU \| CTSB \| CYP11B2 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2E1 \| CYP3A4 \| EGR1 \| ESR1 \| ESR2 \| FASLG \| FOXA1 \| GGT1 \| GJA1 \| GPX3 \| HBG2 \| HSD17B1 \| HSD3B1 \| HSD3B2 \| HSPA1A \| IGF1 \| LDHB \| LEP \| MAPK3 \| MIF \| MPO \| MYC \| NFE2L2 \| NR3C1 \| PRKACB \| PTGS2 \| RPS19 \| RXRA \| SERINC3 \| SHBG \| SOD2 \| SULT1A1 \| SULT2A1 \| TCN2 \| TGFB1 \| TP53 \| VEGFA \| VIP	74.70	97
15.	DDT	Carcinoma, Hepatocellular	M	38 genes: ABCB1 \| ACTB \| AKR1B10 \| AR \| CCND1 \| CDK4 \| CDKN2A \| CEBPA \| CTNNB1 \| CTSD \| CXCL12 \| CYP17A1 \| CYP1A1 \| E2F1 \| EGF \| ENO1 \| EPHX1 \| ESR1 \| FOS \| GJB1 \| HGF \| HSPA5 \| IGF2 \| JUN \| MET \| MT2A \| MYC \| PCK1 \| PPARG \| PTGS2 \| RB1 \| SOD2 \| STAT1 \| TGFB1 \| TNF \| TP53 \| TRP53 \| TYMS	69.06	45
16.	Lindane	Breast Neoplasms	M	54 genes: ABCB1 \| ABCG2 \| ACHE \| ACVR1 \| AHR \| AR \| BAX \| BCHE \| BCL2 \| CASP7 \| CAT \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2B1 \| CYP2D6 \| CYP3A4 \| DAP3 \| EEF1B2 \| ESR1 \| ESR2 \| ESRRA \| FASN \| FN1 \| FOS \| FOXA1 \| IFNG \| IGF1 \| JUN \| KIT \| LAMTOR5 \| LDHB \| LEP \| MIF \| NDUFS3 \| NOS2 \| NR2F6 \| PABPC1 \| PGR \| PTGS2 \| RAF1 \| RARA \| RB1 \| RELA \| RGS2 \| RPL31 \| RPS6 \| RXRB \| SNAI2 \| SOD2 \| TNF \| TP53 \| XRCC2	66.01	80
17.	Dinitrochlorobenzene	Hypersensitivity	M	27 genes: CCL11 \| CCL12 \| CCL17 \| CCL2 \| CCL3 \| CCL4 \| CCL7 \| CCL8 \| CCL9 \| CCR1 \| CCR2 \| CD274 \| CXCL1 \| CXCL5 \| CXCR2 \| CYP1A1 \| IFNG \| IL13 \| IL17A \| IL18 \| IL1B \| IL4 \| IL6 \| PF4 \| PPBP \| SPP1 \| TNF	63.90	8
18.	Dichlorodiphenyl Dichloroethylene	Obesity	M	29 genes: ADIPOQ \| AHR \| CYCS \| DDIT3 \| DPYD \| ESR1 \| FASN \| FOXO3 \| GH1 \| IGF2 \| IL6 \| INS \| LDLR \| LEP \| NR1I2 \| NR1I3 \| NTRK2 \| PARP1 \| PCK1 \| POMC \| PPARG \| PTGS2 \| SCD1 \| SOD1 \| SREBF1 \| STS \| TF \| TNF \| TNFRSF1B	63.00	39
19.	Dinitrochlorobenzene	Dermatitis, Contact	M	26 genes: AKR1B10 \| AKR1C2 \| CCR1 \| CD86 \| CXCL14 \| CYP1A1 \| DDIT3 \| DUSP1 \| FTH1 \| G6PD \| GCLC \| GSR \| GSTP1 \| HMOX1 \| IGFBP6 \| IL18 \| MMP10 \| NQO1 \| OSM \| PIR \| SOD1 \| SOD3 \| TXN \| TXNRD1 \| UGT1A6 \| VEGFA	62.67	5
20.	Dichlorodiphenyl Dichloroethylene	Diabetes Mellitus, Type 2	M	27 genes: ADIPOQ \| ATF3 \| BCL2 \| CASP3 \| CASP8 \| CAT \| CYBA \| CYP3A23/3A1 \| EGFR \| FAS \| INS \| LEP \| NFKB1 \| NOS2 \| NOS3 \| NOTCH2 \| PAM \| PPARG \| PPARGC1A \| RELA \| RETN \| SHBG \| SLC2A4 \| SOD1 \| TGFB1 \| TNF \| TNFRSF1B	59.94	36
21.	Dieldrin	Lung Neoplasms	M	54 genes: ACTB \| APOA1 \| APOE \| BCL2L1 \| BIRC5 \| CASP8 \| CCND1 \| CDKN1A \| CDKN1C \| CHEK2 \| CHRNA3 \| CHRNA5 \| CHRNA7 \| CHRNB4 \| CYP1A2 \| CYP1B1 \| DNASE1L3 \| EGFR \| EPHX1 \| ERBB3 \| ESR1 \| FGF9 \| FGFR1 \| FOS \| GJA1 \| GPX1 \| GPX3 \| GSTP2 \| HMOX1 \| IL10 \| IL1B \| IL6 \| JAG1 \| JUN \| JUNB \| MAP2K7 \| MAPK1 \| MAPK3 \| MET \| MYC \| NOTCH2 \| PCNA \| PON1 \| PRDX6 \| PYCARD \| RAF1 \| RARB \| TGFB1 \| TNF \| TP53 \| TRP53 \| VHL \| WNT5A \| WT1	57.61	65
22.	DDT	Colonic Neoplasms	M	29 genes: BCL2 \| CCND1 \| CCND2 \| CDKN1A \| CTNNB1 \| DNMT1 \| ERBB2 \| IGF2 \| IL1B \| JUN \| LEP \| LPL \| LTF \| MAP2K6 \| MYC \| NFKB1 \| NOS2 \| NOTCH1 \| OXT \| PPARG \| PTGS2 \| SERPINB5 \| SOD2 \| SPARC \| STAT3 \| TNF \| TP53 \| TYMS \| VEGFA	56.29	42
23.	Lindane	Carcinoma, Hepatocellular	M	38 genes: ABCB1 \| ACLY \| ACO2 \| ACTB \| APOA1 \| AR \| BCL2L1 \| CEBPB \| CRP \| CYP17A1 \| CYP1A1 \| CYP2E1 \| ESR1 \| F2 \| FASN \| FOS \| GLUL \| HSD3B2 \| HSPA5 \| HSPA9 \| IDH1 \| JUN \| MBTPS2 \| MPO \| MT1A \| MYC \| NFE2L2 \| NR0B2 \| PGD \| PTGS2 \| RARA \| RB1 \| RPS6 \| SOD2 \| SREBF1 \| TGFB1 \| TNF \| TP53	55.70	36
24.	Hexachlorobenzene	Neoplasm Invasiveness	M	24 genes: AHR \| ANXA1 \| CAT \| CDH1 \| CDKN2A \| CXCR4 \| CYP2E1 \| EGFR \| ESR1 \| FN1 \| GLYCAM1 \| HMOX1 \| IL1B \| IL6 \| MAPK1 \| MAPK3 \| MMP2 \| MMP9 \| PRDX2 \| SOD2 \| SRC \| TF \| TGFB1 \| TIMP1	54.37	40
25.	Heptachlor	Breast Neoplasms	M	24 genes: ABCB1 \| ABCC1 \| ABCG2 \| AR \| BCL2 \| CDH1 \| CTNNB1 \| CYP19A1 \| ESR1 \| ESR2 \| EZH2 \| FN1 \| HRAS \| IGF1 \| JUN \| MAP3K1 \| MMP9 \| PGR \| RAF1 \| RB1 \| SLC2A2 \| TGM2 \| TP53 \| VIM	46.03	53
26.	3,4,5,3',4'-pentachlorobiphenyl	Neoplasm Metastasis	M	45 genes: ACKR3 \| AGTR1 \| AHR \| ANXA4 \| AXL \| CAT \| CAV1 \| CDH1 \| CDH2 \| CSF3 \| CXCL12 \| CYP19A1 \| DMD \| EGF \| EIF1AX \| ENPP2 \| ESR1 \| FGF13 \| FLT1 \| FTL \| GDF15 \| HGF \| IGF1 \| IL18 \| IL6 \| LCN2 \| LGALS3 \| MAPK1 \| MAPK3 \| MET \| MMP2 \| MMP9 \| PDE5A \| PRNP \| PTGS2 \| SLC7A11 \| SNAI1 \| SOD2 \| SPP1 \| STAT3 \| TLR4 \| TNF \| TP53 \| VEGFA \| VIM	45.34	52
27.	Methoxychlor	Obesity	M	28 genes: ADRB2 \| AHR \| AKT1 \| CTF1 \| CYB5A \| CYCS \| CYP26B1 \| CYP2E1 \| DDIT3 \| ESR1 \| FOXO3 \| GNAS \| GPX1 \| GPX3 \| HSD11B1 \| HTR2C \| IL6 \| IRS1 \| NR1I2 \| NR1I3 \| NTRK2 \| PCK1 \| PPARD \| SDC3 \| SERPINE1 \| SOD1 \| STS \| TNF	44.34	27
28.	Trichloroethylene	Carcinoma	M	47 genes: ABCB1 \| ACSL1 \| ACTB \| ALCAM \| ANGPTL4 \| ATPIF1 \| BASP1 \| BCL2 \| BCL2L1 \| CCND1 \| COL5A1 \| CSN2 \| DNMT1 \| DNMT3B \| EEF1A1 \| EGFR \| EIF5A \| ENO1 \| G0S2 \| GATM \| GDA \| GSTT1 \| IL6ST \| LSR \| MET \| MYC \| PEBP1 \| PGAM1 \| PKM \| PPARA \| PRDX2 \| PRLR \| PTEN \| PTGS2 \| RAN \| RASGRF2 \| RPL3 \| S1PR1 \| SCD \| SPINT2 \| STMN1 \| TGFB1 \| TKT \| TP53 \| TSC22D1 \| UCP2 \| VHL	40.93	21
29.	Chlorodiphenyl (54% Chlorine)	Carcinoma, Hepatocellular	M	55 genes: ACLY \| ACO2 \| ACOX1 \| ACTB \| ANXA4 \| APEX1 \| APOA1 \| AR \| C9 \| CASP8 \| CCND1 \| CEBPA \| CP \| CTNNB1 \| CXCL8 \| CYP1A1 \| CYP2E1 \| EAF2 \| EPHX1 \| ESR1 \| ETFA \| F2 \| FASN \| FATE1 \| FOS \| GAPDH \| GLUL \| GNMT \| GSTM1 \| GSTP1 \| HMGCR \| HRAS \| HSPA5 \| HSPA9 \| IGBP1 \| IGF1R \| ITIH3 \| JUN \| KRAS \| ME1 \| MED1 \| MT1A \| MVK \| NFE2L2 \| PCK1 \| PDIA3 \| PGD \| PGK1 \| PPARG \| PYCARD \| RRM1 \| SLC2A1 \| TH \| TNFSF10 \| TRP53	40.58	49
30.	alpha-hexachlorocyclohexane	Carcinoma, Hepatocellular	M	18 genes: ABCB4 \| AR \| CA2 \| CYP1A1 \| CYP2E1 \| EGF \| EPHX1 \| ESR1 \| FOS \| GAPDH \| GSTP1 \| HGF \| HSPB1 \| ME1 \| MYC \| RB1 \| TP53 \| TRP53	40.45	25
31.	Polychlorinated Biphenyls	Colorectal Neoplasms	M	30 genes: ABCC13 \| AKT1 \| ARNT \| AURKA \| BIRC5 \| BUB1B \| CYP1A2 \| CYP1B1 \| EP300 \| ESR2 \| FEN1 \| GGH \| GPNMB \| KRAS \| LAMA1 \| LY96 \| MKI67 \| NQO1 \| NR4A2 \| POLE \| PTGS2 \| RRM2 \| SOD2 \| TGFB1 \| TK1 \| TNF \| TP53 \| TRPM7 \| TYMS \| UNG	39.71	47
32.	Dinitrochlorobenzene	Dermatitis, Atopic	M	16 genes: CCL11 \| CCL17 \| CCL5 \| CCR3 \| CCR5 \| CXCL10 \| IFNG \| IL10 \| IL13 \| IL1B \| IL31 \| IL4 \| IL5 \| IL6 \| MAPK8 \| TSLP	38.75	11
33.	Trichloroethylene	Breast Neoplasms	M	84 genes: ABCB1 \| ANGPTL4 \| AURKA \| BAG1 \| BARD1 \| BAX \| BCL2 \| BCL2A1 \| BIRC5 \| C1QBP \| CCND1 \| CD74 \| COMT \| CPT1A \| CSF1 \| CTNNB1 \| CXCL8 \| CXCR4 \| CYP1A1 \| CYP1B1 \| DDIT3 \| DLL1 \| DNMT1 \| DNMT3A \| DNMT3B \| EEF2 \| EGF \| EGFR \| ENO1 \| ERBB2 \| ERBB3 \| EVL \| FASN \| FGFR2 \| FOXM1 \| FOXP3 \| GPNMB \| GUCY1A2 \| HADHB \| HMMR \| HMOX1 \| HP \| HSP90AA1 \| IFNG \| IGFBP5 \| IL1B \| IL6 \| JUN \| KDR \| LEPR \| MDM2 \| MFGE8 \| MKI67 \| MTDH \| MTR \| NAT2 \| NCOR1 \| NFKBIA \| NOS2 \| NOS3 \| NOTCH2 \| NR2F6 \| NRG1 \| PER3 \| PPM1D \| PRC1 \| PTEN \| PTGS2 \| RAD51 \| RAD51B \| RELA \| RPL31 \| RPS4X \| RPS8 \| SLC2A2 \| SPP1 \| STMN1 \| TFAP2A \| TGM2 \| TNF \| TP53 \| UBE2C \| VIM \| YBX1	38.05	131
34.	Picryl Chloride	Inflammation	M	12 genes: CASP1 \| IFNG \| IL10 \| IL1B \| IL6 \| MMP2 \| MPO \| NGF \| PPARA \| TLR2 \| TLR4 \| TNF	37.92	41
35.	DDT	Hypertension	M	35 genes: AHR \| ALB \| AR \| ATP1A1 \| BCL2 \| CAT \| COL1A1 \| CYP1A1 \| FN1 \| FOS \| GAL \| GCLC \| GJA1 \| GNRH1 \| GSK3B \| IGF1 \| IL1B \| JUN \| LEP \| LHB \| LPL \| LTF \| NOS2 \| NR3C1 \| OXT \| PLAT \| POMC \| PPARG \| PTGS2 \| SLC12A2 \| SOD1 \| SOD2 \| TGFB1 \| TNF \| TP53	37.25	111
36.	Trichloroethylene	Carcinoma, Hepatocellular	M	58 genes: A2M \| ABCB1 \| ACOX1 \| ACTB \| APC \| ATP5H \| BCL2L1 \| BIRC5 \| C9 \| CCND1 \| CEBPB \| COMT \| CTNNB1 \| CXCL8 \| CYP1A1 \| CYP2E1 \| CYR61 \| EGF \| EGFR \| ENO1 \| F2 \| FASN \| FDFT1 \| FOXM1 \| GDF15 \| GLUL \| GNMT \| HMGCR \| HSPA5 \| HSPB1 \| IL6 \| IRF2 \| JUN \| ME1 \| MED1 \| MET \| MT1A \| MTOR \| MVK \| MYC \| NFKBIA \| NR0B2 \| PCK1 \| PDGFB \| PDIA3 \| PKM \| PPARG \| PRDX2 \| PTEN \| PTGS2 \| SCD \| SERPINA1 \| SLC2A2 \| TGFB1 \| TNF \| TP53 \| UBD \| VCAM1	37.14	54
37.	3,4,5,3',4'-pentachlorobiphenyl	Liver Cirrhosis	M	33 genes: A2M \| ALAD \| ALB \| ARNT \| C1QB \| CCL2 \| CD14 \| COL1A1 \| COL3A1 \| CP \| CTGF \| CYP1A2 \| DHCR7 \| F2R \| F3 \| FBN1 \| FGF2 \| FGFR2 \| FLT1 \| HGF \| HSD11B2 \| IGFBP1 \| IGFBP2 \| IL6 \| JUND \| LOX \| MMP2 \| NFE2L2 \| SPARC \| SPP1 \| STAT1 \| VEGFA \| VIM	36.27	34
38.	Dichlorodiphenyl Dichloroethylene	Endometriosis	M	17 genes: AKR1B1 \| C1R \| CYP19A1 \| CYP26A1 \| DIO2 \| EGFR \| ESR2 \| FOS \| IGF1 \| NR3C1 \| NR4A1 \| NR5A1 \| PGR \| PRL \| PTGS2 \| SRD5A2 \| THRA	35.60	12
39.	Hexachlorobenzene	Mammary Neoplasms, Animal	M	15 genes: ANXA1 \| CCND1 \| CDH1 \| COMT \| EGFR \| EPHX1 \| ESR1 \| FN1 \| GLYCAM1 \| IL6ST \| PRDX2 \| PRL \| S100A8 \| TF \| TSC22D1	35.01	12
40.	DDT	Infertility, Male	M	16 genes: AHR \| AR \| BCL2 \| CFTR \| CYP17A1 \| CYP1A1 \| ENO1 \| ESR1 \| FSHB \| GNRH1 \| LHB \| MDM2 \| OGG1 \| SOD2 \| TP53 \| TSC22D3	35.00	21
41.	Lindane	Lung Neoplasms	M	29 genes: ACTB \| APOA1 \| BCL2L1 \| BECN1 \| CCNG1 \| CDKN1A \| CRP \| CYP1A2 \| CYP1B1 \| CYP2E1 \| ESR1 \| FAS \| FASLG \| FOS \| GJA1 \| GPX3 \| IFNG \| JUN \| MAPK1 \| MAPK3 \| MPO \| MYC \| NOS2 \| RAF1 \| SELENBP1 \| SLC3A2 \| TGFB1 \| TNF \| TP53	34.23	39
42.	Methoxychlor	Infertility, Female	M	15 genes: ADIPOR1 \| AR \| CEBPA \| CYP17A1 \| CYP19A1 \| ESR1 \| ESR2 \| FSHB \| LHB \| LIF \| MAPK1 \| MAPK3 \| NR1I2 \| PAPPA \| PRL	33.32	12
43.	DDT	Liver Neoplasms	M	23 genes: AHR \| CCND1 \| CDKN2A \| CTNNB1 \| ESR1 \| GJB1 \| HGF \| IGF2 \| IL2 \| JUN \| KRT18 \| KRT8 \| LTF \| MALAT1 \| MAPK14 \| MYC \| NEAT1 \| NR1I3 \| PPARG \| SNHG11 \| STAT3 \| TNF \| TP53	33.11	30
44.	Chloroform	Drug-Induced Liver Injury	M	22 genes: ABCB1 \| ABCB1B \| ANXA2 \| CAT \| CCL2 \| CLU \| CYP2E1 \| CYP3A23/3A1 \| FADS1 \| FGA \| GADD45A \| GPT \| GSR \| GSTM3 \| HAVCR1 \| HMOX1 \| IFNG \| IL4 \| KRT18 \| LBP \| LGALS3 \| TTR	32.77	32
45.	DDT	Obesity	M	19 genes: ADRB2 \| AHR \| DDIT3 \| ESR1 \| HSPA5 \| IGF2 \| LEP \| LPL \| MIR21 \| NR1I2 \| NR1I3 \| NTRK2 \| PCK1 \| POMC \| PPARG \| PTGS2 \| SOD1 \| SOD2 \| TNF	32.32	33
46.	Picryl Chloride	Dermatitis, Atopic	M	7 genes: IFNG \| IL10 \| IL1B \| IL4 \| IL6 \| MAPK8 \| PPARA	31.57	6
47.	beta-hexachlorocyclohexane	Prostatic Neoplasms	M	18 genes: AKAP13 \| AR \| ATP7B \| BRCA1 \| CASP9 \| CCND1 \| CDKN1B \| ERBB2 \| ERBB3 \| ESR1 \| ESR2 \| ETV1 \| FASLG \| GSTM1 \| HMOX1 \| MAPK3 \| MMP13 \| MMP9	31.54	50
48.	Polychlorinated Biphenyls	Endometriosis	M	20 genes: AKR1C3 \| ANKRD1 \| AREG \| ARNT \| CYP19A1 \| DUSP1 \| ESR2 \| FBN1 \| FOS \| GREB1 \| IGFBP1 \| KRAS \| NR2C2 \| NR3C1 \| PAPPA \| PTGER4 \| PTGS2 \| STC2 \| TGFB2 \| THRA	31.48	12
49.	beta-hexachlorocyclohexane	Breast Neoplasms	M	19 genes: AR \| ATP7B \| BRCA1 \| CASP8 \| CAT \| CCND1 \| CDKN1B \| CPT1A \| ERBB2 \| ERBB3 \| ESR1 \| ESR2 \| HMOX1 \| IGF1R \| JUN \| MMP9 \| PGR \| RELA \| SRC	31.10	85
50.	Polychlorinated Biphenyls	Adenocarcinoma	M	24 genes: APOE \| BIRC5 \| CDKN2A \| CYP19A1 \| DNMT1 \| ESR1 \| ESR2 \| GHRL \| HSPD1 \| ID3 \| KRAS \| MKI67 \| MTOR \| MYC \| NCOA3 \| PCNA \| PTGS2 \| PTPN11 \| SOD2 \| SPP1 \| TGFB1 \| TNF \| TP53 \| TPM3	30.49	27

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