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Chemical benzo(a)pyrene-DNA adduct

These diseases are associated with benzo(a)pyrene-DNA adduct. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 128 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Prostatic Neoplasms  
4 genes: BRCA1 | CYP1A1 | CYP1B1 | EPHX1 		14.38 6
Has associated exposure references.
2. Breast Neoplasms  
4 genes: BRCA1 | CAT | CYP1A1 | CYP1B1 		13.67 16
3. Cell Transformation, Neoplastic  
3 genes: BRCA1 | CAT | POR 		12.70 6
4. Chromosome Breakage  
2 genes: BRCA1 | CAT 		9.81 2
5. Pulmonary Disease, Chronic Obstructive  
2 genes: CYP1A1 | EPHX1 		9.78 2
6. Acute Lung Injury  
2 genes: CAT | EPHX1 		9.41 2
7. Precursor Cell Lymphoblastic Leukemia-Lymphoma  
2 genes: CYP1B1 | EPHX1 		9.15 2
Has associated exposure references.
8. Mammary Neoplasms, Animal  
2 genes: BRCA1 | EPHX1 		8.69 2
9. Dermatitis, Contact  
2 genes: CYP1A1 | CYP1B1 		8.60 1
10. Micronuclei, Chromosome-Defective  
2 genes: CYP1A1 | EPHX1 		8.53 2
11. Ovarian Neoplasms  
2 genes: BRCA1 | CYP1B1 		8.44 6
12. Abnormalities, Drug-Induced  
2 genes: CAT | EPHX1 		8.32 3
13. Carcinoma  
2 genes: BRCA1 | EPHX1 		8.08 2
14. Mammary Neoplasms, Experimental  
2 genes: BRCA1 | EPHX1 		8.06 3
15. Diabetes Mellitus, Experimental  
2 genes: CAT | CYP1A1 		7.98 4
16. Cardiomegaly  
2 genes: CYP1A1 | CYP1B1 		7.91 1
17. Neoplasms  
2 genes: BRCA1 | CAT 		7.23 2
18. Methemoglobinemia Type IV     1 gene: CYB5A 7.22 1
19. BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1     1 gene: BRCA1 7.12 1
20. Lung Neoplasms  
2 genes: CYP1B1 | EPHX1 		7.04 3
21. Carcinoma, Hepatocellular  
2 genes: CYP1A1 | EPHX1 		7.01 2
22. ANTLEY-BIXLER SYNDROME WITH GENITAL ANOMALIES AND DISORDERED STEROIDOGENESIS     1 gene: POR 6.89 1
23. Hereditary Breast and Ovarian Cancer Syndrome     1 gene: BRCA1 6.77 2
24. Glaucoma 3, Primary Congenital, A     1 gene: CYP1B1 6.62 1
25. ANTLEY-BIXLER SYNDROME WITHOUT GENITAL ANOMALIES OR DISORDERED STEROIDOGENESIS     1 gene: POR 6.54 1
26. Antley-Bixler Syndrome Phenotype     1 gene: POR 6.34 5
27. Acatalasia     1 gene: CAT 6.32 5
28. Hypercholanemia, Familial     1 gene: EPHX1 6.31 1
29. Glaucoma 3, primary infantile, B     1 gene: CYP1B1 6.28 1
30. Peters anomaly     1 gene: CYP1B1 5.93 1
31. Gliosarcoma     1 gene: POR 5.79 1
32. Hypertension  
2 genes: CAT | CYP1A1 		5.64 6
33. Adrenal Hyperplasia, Congenital     1 gene: POR 5.61 1
34. Hyperoxia     1 gene: CYP1A1 5.50 1
35. Mouth Diseases     1 gene: BRCA1 5.49 1
36. Protein Deficiency     1 gene: CAT 5.42 1
37. Pulmonary Emphysema     1 gene: EPHX1 5.42 1
38. Hamartoma     1 gene: CYP1A1 5.41 1
39. Drug-Induced Liver Injury  
2 genes: CAT | EPHX1 		5.38 2
40. Fetal Alcohol Spectrum Disorders     1 gene: CAT 5.34 1
41. Turner Syndrome     1 gene: CAT 5.34 1
42. Asphyxia Neonatorum     1 gene: CAT 5.28 1
43. Amenorrhea     1 gene: POR 5.11 1
44. Keratosis     1 gene: CAT 5.07 1
45. Marfan Syndrome     1 gene: CAT 5.03 1
46. Phobic Disorders     1 gene: CAT 4.90 1
47. Pre-Eclampsia     1 gene: EPHX1 4.86 3
48. Respiratory Distress Syndrome, Adult     1 gene: CYB5A 4.86 1
49. Carcinoma, Adenoid Cystic     1 gene: BRCA1 4.82 1
50. Arteritis     1 gene: CYP1A1 4.81 1
1–50 of 128 results.
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