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Chemical 3,6-dinitrobenzopyrene

These diseases are associated with 3,6-dinitrobenzopyrene. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 56 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Prostatic Neoplasms  
3 genes: CYP1A1 | CYP3A4 | NAT2 		12.03 7
2. Breast Neoplasms  
3 genes: CYP1A1 | CYP3A4 | NAT2 		11.54 3
3. Pulmonary Disease, Chronic Obstructive  
2 genes: CYP1A1 | CYP1A2 		10.64 2
4. Neural Tube Defects  
2 genes: CYP1A2 | NAT2 		10.32 1
5. Precursor Cell Lymphoblastic Leukemia-Lymphoma  
2 genes: CYP1A2 | NAT2 		10.23 2
Has associated exposure references.
6. Lung Injury  
2 genes: CYP1A1 | CYP1A2 		9.75 2
7. Drug-Related Side Effects and Adverse Reactions  
2 genes: CYP1A2 | NAT2 		7.77 3
8. Dermatitis, Occupational     1 gene: NAT2 6.07 1
9. Hyperoxia     1 gene: CYP1A1 5.78 1
10. Hamartoma     1 gene: CYP1A1 5.69 1
11. Mesothelioma, Malignant     1 gene: NAT2 5.12 1
12. Arteritis     1 gene: CYP1A1 5.09 1
13. Splenic Diseases     1 gene: CYP1A2 5.06 1
14. Coronary Artery Disease     1 gene: NAT2 5.00 1
15. Porphyria Cutanea Tarda     1 gene: CYP1A2 4.97 1
16. Leukopenia     1 gene: NAT2 4.91 1
17. Peripheral Vascular Diseases     1 gene: CYP1A1 4.81 1
18. Methemoglobinemia     1 gene: CYP1A2 4.79 1
19. Hepatitis C     1 gene: CYP3A4 4.71 1
20. Urinary Bladder Neoplasms     1 gene: NAT2 4.67 5
21. Drug Hypersensitivity     1 gene: NAT2 4.66 3
22. Birth Weight     1 gene: CYP1A1 4.59 1
23. Osteosarcoma     1 gene: CYP3A4 4.55 1
24. Occupational Diseases     1 gene: CYP1A1 4.53 1
25. Splenomegaly     1 gene: CYP1A2 4.50 1
26. Liver Neoplasms     1 gene: NAT2 4.47 1
27. Tachycardia, Sinus     1 gene: CYP1A1 4.42 1
Has associated exposure references.
28. Growth Disorders     1 gene: CYP1A2 4.40 1
29. Non-alcoholic Fatty Liver Disease     1 gene: CYP1A2 4.34 1
30. Atrophy     1 gene: CYP1A2 4.28 1
31. Kidney Neoplasms     1 gene: CYP1A1 4.14 1
32. Torsades de Pointes     1 gene: CYP3A4 4.14 1
33. Infertility, Male     1 gene: CYP1A1 4.09 1
34. Abortion, Spontaneous     1 gene: CYP1A1 4.05 2
35. Dermatitis, Contact     1 gene: CYP1A1 4.02 1
36. Carcinoma, Squamous Cell     1 gene: CYP1A2 4.01 1
37. Hypersensitivity     1 gene: CYP1A1 3.98 1
38. Micronuclei, Chromosome-Defective     1 gene: CYP1A1 3.97 1
39. Diabetes Mellitus, Type 2     1 gene: CYP1A2 3.94 1
40. Long QT Syndrome     1 gene: CYP1A1 3.94 1
Has associated exposure references.
41. Drug-Induced Liver Injury     1 gene: NAT2 3.93 4
42. Liver Cirrhosis     1 gene: CYP1A2 3.93 1
43. Diabetes Mellitus, Experimental     1 gene: CYP1A1 3.86 1
44. Hepatomegaly     1 gene: CYP1A2 3.86 1
45. Drug Eruptions     1 gene: CYP1A1 3.82 1
46. Cardiomegaly     1 gene: CYP1A1 3.80 1
47. Colorectal Neoplasms     1 gene: CYP1A2 3.78 1
48. Liver Diseases     1 gene: CYP1A2 3.78 1
49. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.76 1
50. Liver Neoplasms, Experimental     1 gene: CYP1A2 3.75 2
1–50 of 56 results.
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