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Disease Osteonecrosis

These chemicals are associated with Osteonecrosis or its descendants. A chemical has either a curated association to the disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated gene interaction.

1–50 of 1,054 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Adrenal Cortex Hormones Femur Head Necrosis M   1 gene: POMC 4.55 1
2. Tretinoin Femur Head Necrosis M
2 genes: COL2A1 | POMC
4.40 3
3. zoledronic acid Osteonecrosis M   1 gene: MMP2 2.94 3
4. Adrenal Cortex Hormones Osteonecrosis M     1
5. Cocaine Osteonecrosis M     2
6. Diphosphonates Osteonecrosis M     2
7. Formaldehyde Osteonecrosis M     1
8. Prednisolone Osteonecrosis M     1
9. Prednisone Osteonecrosis M     1
10. Ergocalciferols Osteonecrosis T     1
11. Acetaldehyde Femur Head Necrosis  
2 genes: COL2A1 | POMC
9.44 2
12. Vitamin A Femur Head Necrosis  
2 genes: COL2A1 | POMC
8.99 2
13. Acrylamide Femur Head Necrosis  
2 genes: COL2A1 | POMC
8.86 2
14. Berberine Alkaloids Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
15. indole-3-carboxylic acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
16. indole-3-lactic acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
17. magnoflorine Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
18. phellodendrine Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
19. phenylacetylglycine Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
20. Pyridoxic Acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.70 1
21. huang-lien-chieh-tu-tang Legg-Calve-Perthes Disease     1 gene: COL2A1 7.49 1
22. Palmitoylcarnitine Legg-Calve-Perthes Disease     1 gene: COL2A1 7.49 1
23. phenylpyruvic acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.49 1
24. isoascorbic acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.35 1
25. xanthurenic acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.35 1
26. 1-palmitoyl-2-lysophosphatidylcholine Legg-Calve-Perthes Disease     1 gene: COL2A1 7.24 1
27. hippuric acid Legg-Calve-Perthes Disease     1 gene: COL2A1 7.24 1
28. punicalagin Legg-Calve-Perthes Disease     1 gene: COL2A1 7.24 1
29. glucosamine 3-O-sulfate Legg-Calve-Perthes Disease     1 gene: COL2A1 7.15 1
30. deethylatrazine Femur Head Necrosis     1 gene: POMC 7.14 1
31. Disulfiram Femur Head Necrosis  
2 genes: COL2A1 | POMC
7.12 2
32. Allantoin Legg-Calve-Perthes Disease     1 gene: COL2A1 7.07 1
33. Berberine Alkaloids Femur Head Necrosis     1 gene: COL2A1 7.00 1
34. indole-3-carboxylic acid Femur Head Necrosis     1 gene: COL2A1 7.00 1
35. indole-3-lactic acid Femur Head Necrosis     1 gene: COL2A1 7.00 1
36. magnoflorine Femur Head Necrosis     1 gene: COL2A1 7.00 1
37. phellodendrine Femur Head Necrosis     1 gene: COL2A1 7.00 1
38. phenylacetylglycine Femur Head Necrosis     1 gene: COL2A1 7.00 1
39. Pyridoxic Acid Femur Head Necrosis     1 gene: COL2A1 7.00 1
40. diacetylrhein Legg-Calve-Perthes Disease     1 gene: COL2A1 7.00 1
41. 3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide Legg-Calve-Perthes Disease     1 gene: COL2A1 6.95 1
42. methyl isothiocyanate Legg-Calve-Perthes Disease     1 gene: COL2A1 6.95 1
43. Isoproterenol Femur Head Necrosis  
2 genes: COL2A1 | POMC
6.92 2
44. huang-lien-chieh-tu-tang Femur Head Necrosis     1 gene: COL2A1 6.80 1
45. Palmitoylcarnitine Femur Head Necrosis     1 gene: COL2A1 6.80 1
46. phenylpyruvic acid Femur Head Necrosis     1 gene: COL2A1 6.80 1
47. dopachrome Femur Head Necrosis     1 gene: POMC 6.79 1
48. p-Aminohippuric Acid Legg-Calve-Perthes Disease     1 gene: COL2A1 6.76 1
49. mofezolac Legg-Calve-Perthes Disease     1 gene: COL2A1 6.72 1
50. Succinic Acid Legg-Calve-Perthes Disease     1 gene: COL2A1 6.72 1
1–50 of 1,054 results.