| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | APOE | 126 | 2 |
| 2. | NFE2L2 | 120 | 2 |
| 3. | IL6 | 87 | 3 |
| 4. | CXCL8 | 73 | 3 |
| 5. | TNF | 56 | 4 |
| 6. | IL1B | 44 | 3 |
| 7. | HMOX1 | 43 | 3 |
| 8. | CYP1A1 | 42 | 3 |
| 9. | MMP9 | 34 | 3 |
| 10. | MAPK1 | 32 | 3 |
| 11. | MAPK3 | 32 | 3 |
| 12. | RELA | 32 | 3 |
| 13. | EGR1 | 27 | 3 |
| 14. | CAT | 26 | 4 |
| 15. | CYP1B1 | 26 | 4 |
| 16. | SIRT1 | 26 | 3 |
| 17. | TLR4 | 26 | 3 |
| 18. | MMP1 | 25 | 2 |
| 19. | AHR | 24 | 2 |
| 20. | CHRNA5 | 23 | 2 |
| 21. | CCL2 | 22 | 3 |
| 22. | CDKN1A | 22 | 3 |
| 23. | NQO1 | 22 | 2 |
| 24. | CASP3 | 21 | 3 |
| 25. | EDNRB | 21 | 3 |
| 26. | SOD2 | 20 | 4 |
| 27. | VEGFA | 20 | 3 |
| 28. | CHRNA7 | 19 | 2 |
| 29. | CYBB | 19 | 2 |
| 30. | CSF2 | 18 | 3 |
| 31. | DDIT3 | 18 | 2 |
| 32. | PTGS2 | 18 | 3 |
| 33. | CDH1 | 17 | 2 |
| 34. | CXCL1 | 17 | 3 |
| 35. | ICAM1 | 17 | 3 |
| 36. | NFKBIA | 17 | 3 |
| 37. | ATF3 | 16 | 2 |
| 38. | GATA2 | 16 | 2 |
| 39. | CXCL2 | 15 | 3 |
| 40. | TIMP1 | 15 | 2 |
| 41. | VCAM1 | 15 | 2 |
| 42. | HOTAIR | 14 | 1 |
| 43. | IL1A | 14 | 3 |
| 44. | PLD1 | 14 | 1 |
| 45. | CXCL10 | 13 | 2 |
| 46. | CXCL5 | 13 | 2 |
| 47. | GSR | 13 | 3 |
| 48. | PPARG | 13 | 2 |
| 49. | TLR2 | 13 | 3 |
| 50. | TP53 | 13 | 2 |