Acids, Carbocyclic - Diseases

These diseases are associated with Acids, Carbocyclic or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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	Chemical	Disease	Direct Evidence	Inference Network	Inference Score	References
1.	Diethylhexyl Phthalate	Breast Neoplasms	M	130 genes: ABCB1 \| ABCB1B \| ABCG2 \| AFP \| AHR \| AKT1 \| AKT2 \| ALDOA \| ANGPTL4 \| AR \| ARRDC3 \| ATM \| BAP1 \| BAX \| BCL2 \| BMP2 \| BMP4 \| CADM1 \| CASP7 \| CASP8 \| CAT \| CAV1 \| CCND1 \| CCNE1 \| CD74 \| CDA \| CDKN2A \| CMC2 \| CPT1A \| CSF2 \| CTNNB1 \| CXCL2 \| CXCL8 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| DHFR \| DNMT1 \| DNMT3A \| DNMT3B \| DPYD \| EDNRB \| EEF2 \| EFNA1 \| EGF \| EGFR \| ERBB2 \| ERBB3 \| ESR1 \| ESR2 \| ESRRA \| FABP7 \| FASN \| FGFR2 \| FOS \| FOXQ1 \| FST \| GPER1 \| GPX1 \| GSTP1 \| HADHB \| HEY1 \| HMOX1 \| HP \| HRAS \| HSP90AA1 \| HSPA1B \| IFNG \| IGF1 \| IGFBP5 \| IGFBP7 \| IL6 \| JAG2 \| JUN \| KIT \| KRT14 \| LEP \| MIR132 \| MIR200B \| MIR200C \| MIR221 \| MIR29A \| MIR345 \| MIR429 \| MIR489 \| MKI67 \| MMP2 \| MMP9 \| NCOA1 \| NDRG1 \| NOS2 \| NOS3 \| NOTCH2 \| NOTCH3 \| NOTCH4 \| NQO1 \| NRCAM \| NRG1 \| PDPK1 \| PGR \| PIK3CA \| PPARGC1B \| PTEN \| PTGS2 \| RAD51B \| RALYL \| RPL31 \| RPS4X \| RPS6 \| RXRB \| SLC2A1 \| SLC2A2 \| SNAI1 \| SOD2 \| SPP1 \| TFPI2 \| TFRC \| THBS1 \| TNF \| TP53 \| TRP53 \| TUBB3 \| VEGFB \| VEGFC \| VIM \| WNT10B \| WT1 \| YBX1	125.20	184
2.	Diethylhexyl Phthalate	Carcinoma, Hepatocellular	M	85 genes: ABCB1 \| ABCB4 \| ACLY \| ACOX1 \| ACTB \| AFP \| APCS \| AR \| ATM \| ATP5H \| BTG2 \| C9 \| CASP8 \| CCNA1 \| CCND1 \| CCNE1 \| CD276 \| CDK4 \| CDKN2A \| CEBPA \| CTNNB1 \| CXCL8 \| CYP17A1 \| CYP1A1 \| DPYD \| EGF \| EGFR \| EPHX1 \| ERP29 \| ESR1 \| FABP5 \| FASN \| FDFT1 \| FOS \| FST \| GDF15 \| GLI1 \| GSTM1 \| GSTP1 \| HMGCR \| HRAS \| HSD3B2 \| HSPA5 \| HSPA9 \| HSPB1 \| HTATIP2 \| IGF2 \| IGF2R \| IL6 \| IRS1 \| IRS2 \| JUN \| ME1 \| MECP2 \| MIR615 \| MMP2 \| MMP9 \| MPO \| MTOR \| MYC \| NFE2L2 \| NR0B2 \| NR1H2 \| PCK1 \| PIK3CA \| PKM \| PKP1 \| PPARG \| PTEN \| PTGS2 \| PYGL \| RPS6 \| SCD \| SLC2A1 \| SLC2A2 \| SOCS3 \| SOD2 \| SREBF1 \| TFPI2 \| TGFB1 \| TH \| TNF \| TP53 \| TRP53 \| TSC1	96.56	70
3.	Puromycin Aminonucleoside	Hypertension	M	49 genes: ACE \| AGT \| AGTR2 \| ALB \| APOA1 \| APOE \| ATP1A1 \| AVP \| BCL2 \| CAT \| CCL2 \| CD36 \| COL1A1 \| COL3A1 \| ECE1 \| EDN1 \| EDN3 \| EDNRA \| FN1 \| GNRH1 \| GPX1 \| GSK3B \| HMOX1 \| HSD11B2 \| ICAM1 \| IL1B \| LHB \| MMP2 \| NEDD4L \| NOS2 \| NOS3 \| NPPA \| NPPB \| NPR1 \| PPARG \| PTGS2 \| PTH \| REN \| SCNN1A \| SCNN1B \| SCNN1G \| SERPINE1 \| SLC12A3 \| SOD2 \| SOD3 \| TGFB1 \| TIMP1 \| TNF \| TP53	90.89	153
4.	mono-(2-ethylhexyl)phthalate	Breast Neoplasms	M	60 genes: ABCB1B \| AHR \| AKT1 \| AR \| ARRDC3 \| ARTN \| BAX \| BCL2 \| CADM1 \| CASP7 \| CAT \| CCND1 \| CD109 \| CD40 \| CPT1A \| CTNNB1 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP3A4 \| DDIT3 \| DNMT1 \| DNMT3B \| EGF \| EP300 \| EPB41L3 \| ESR1 \| F3 \| FASN \| FOS \| FOXA1 \| GPX1 \| HSP90AA1 \| HSPA1B \| IL6 \| JUN \| LOXL2 \| MDM2 \| MIF \| MMP2 \| NCOA1 \| NCOR1 \| NDRG1 \| NFKBIA \| NRCAM \| NRG1 \| OCLN \| PER3 \| PTGS2 \| PTPRD \| RECQL \| RRAD \| RXRB \| THBS1 \| TNF \| TOX3 \| TP53 \| TRP53 \| VIM	65.77	87
5.	mono-(2-ethylhexyl)phthalate	Prostatic Neoplasms	M	53 genes: ACSL4 \| AHR \| AKT1 \| AOX1 \| AR \| ATF3 \| BAX \| BCL2 \| CASP9 \| CCND1 \| CCND2 \| CDKN1A \| CTNNB1 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP1B1 \| CYP2C19 \| CYP3A4 \| DIABLO \| DNMT1 \| DNMT3B \| EGF \| EGR1 \| EPHX1 \| ESR1 \| FOXA1 \| GJA1 \| GPX3 \| GSTM1 \| IL16 \| IL17RD \| IL6 \| IRS1 \| ITGB3 \| KLF15 \| KLK3 \| MAPK3 \| MDM2 \| MIF \| MPO \| MYC \| NCOA1 \| NDRG1 \| PDE4D \| PPARA \| PRDX2 \| PRNP \| PTGS2 \| RXRA \| TP53 \| VIM \| ZBTB16	60.66	87
6.	Eugenol	Dermatitis, Allergic Contact	M	26 genes: ABCA6 \| BCL2 \| BMP6 \| CALCRL \| CCL19 \| CCR2 \| CD36 \| CISH \| CREM \| CYP1A1 \| EMB \| F13A1 \| IFNG \| IL10 \| IL18 \| IL2 \| IPCEF1 \| MXD1 \| NAMPT \| NFE2L2 \| PLAT \| RGS1 \| SAT1 \| SLC2A3 \| TNF \| TNFAIP6	60.57	12
7.	Bezafibrate	Carcinoma, Hepatocellular	M	32 genes: ABCB1 \| ABCB4 \| ACACA \| ACE \| ACOX1 \| ACSL4 \| APEX1 \| APOA1 \| CCL3 \| CDK4 \| CRP \| CXCL8 \| CYP17A1 \| CYP1A1 \| FASN \| FOS \| HMGCR \| IL6 \| JUN \| NR0B2 \| NR1H2 \| NR1H4 \| PCK1 \| PPARG \| SCAP \| SCD \| SLC2A2 \| SREBF1 \| SREBF2 \| TGFB1 \| TNF \| VCAM1	58.28	28
8.	Eugenol	Dermatitis, Contact	M	21 genes: AHR \| AKR1B10 \| AKR1C2 \| BCL2 \| CD86 \| CYP1A1 \| CYP1B1 \| G6PD \| GCLC \| GSR \| GSTP1 \| HMOX1 \| IL18 \| NQO1 \| SLC7A11 \| SOD1 \| SOD3 \| TLR4 \| TXNRD1 \| UGT1A1 \| UGT1A6	55.43	4
9.	Puromycin Aminonucleoside	Liver Cirrhosis, Experimental	M	35 genes: AGT \| ALB \| APOA4 \| BMP7 \| CCL2 \| CD36 \| CDKN1A \| CHSY1 \| COL1A1 \| COL3A1 \| COL4A1 \| DDC \| EDN1 \| EZR \| FAT1 \| HMGCR \| HMOX1 \| HPSE \| IL1B \| ILK \| ITGB1 \| LCN2 \| LGALS1 \| MME \| MMP2 \| MSN \| NOS2 \| NOS3 \| PTGS2 \| PTPRO \| TGFB1 \| TIMP1 \| TNF \| VEGFA \| VIM	54.32	30
10.	diethyl phthalate	Breast Neoplasms	M	21 genes: AFP \| AHR \| AR \| BAX \| BCL2 \| CASP8 \| CAT \| CDKN2A \| CXCL8 \| CYP17A1 \| CYP19A1 \| CYP1B1 \| CYP2B1 \| ESR1 \| ESR2 \| GPX1 \| IFNB1 \| IGF1 \| PGR \| RXRB \| TNF	51.72	48
11.	Eugenol	Hypersensitivity	M	19 genes: CCL19 \| CCL2 \| CCL3 \| CCL4 \| CCR2 \| CD274 \| CLEC4A \| CXCL1 \| CYP1A1 \| HLA-B \| IFNG \| IL16 \| IL18 \| IL1B \| IL1R2 \| IL6 \| PPBP \| TAC1 \| TNF	46.91	9
12.	phthalic anhydride	Hypersensitivity	M	10 genes: CCL11 \| CCL2 \| CCL4 \| CYP1A1 \| IFNG \| IL13 \| IL18 \| IL4 \| IL6 \| TNF	44.85	6
13.	Diclofenac	Drug-Induced Liver Injury	M	60 genes: ABCB1A \| ABCB1B \| ABCC1 \| ABCC2 \| AIFM1 \| ALB \| ARNT \| BAX \| CAT \| CCL2 \| CLU \| CTNNB1 \| CXCL1 \| CYP2C19 \| CYP2C9 \| CYP2K18 \| CYP3A23/3A1 \| DHFR \| DNAJB9 \| EIF2AK1 \| EPHX1 \| FASN \| GADD45A \| GC \| GCLC \| GOT1 \| GPT \| GSR \| GSTM1 \| GSTM2 \| GSTM4 \| GSTP1 \| GSTT1 \| GSTT1B \| HAVCR1 \| HLA-DRB1 \| HMGB1 \| HMOX1 \| IFNG \| IL17A \| IL1A \| IL1B \| IL4 \| IL6 \| KNG1 \| LCN2 \| MIR122 \| NFE2L2 \| NR1I2 \| NR1I3 \| POLG \| PTGS2 \| RGN \| SLC22A8 \| SOD2 \| SORD \| TNF \| TTR \| UGT1A9 \| VIM	41.28	112
14.	Puromycin Aminonucleoside	Glomerulosclerosis, Focal Segmental	M	13 genes: AGT \| CD2AP \| COL4A1 \| EDN1 \| FN1 \| GNAQ \| MYH10 \| NOS2 \| NPHS1 \| NPHS2 \| SERPINE1 \| SPP1 \| TGFB1	40.45	27
15.	phthalic anhydride	Dermatitis, Allergic Contact	M	9 genes: CYP1A1 \| IFNG \| IL10 \| IL18 \| IL1A \| IL2 \| IL4 \| IL5 \| TNF	35.31	9
16.	diisononyl phthalate	Dermatitis, Atopic	M	9 genes: CCL11 \| CCL17 \| CCL22 \| CCL24 \| FLG \| IFNG \| IL4 \| PPARA \| TSLP	35.23	12
17.	Benzoic Acid	Dermatitis, Contact	M	10 genes: AKR1B10 \| BCL2 \| G6PD \| GCLC \| GSR \| HMOX1 \| NQO1 \| TXN \| TXNRD1 \| VEGFA	33.42	2
18.	Dibutyl Phthalate	Neoplasm Metastasis	M	76 genes: ABCC4 \| AHR \| ALDOA \| ANGPTL4 \| ANXA1 \| ARHGDIA \| AXL \| BSG \| CAT \| CAV1 \| CD44 \| CD82 \| CDH1 \| CDH2 \| CFL1 \| CLIC1 \| CXCL12 \| CYP19A1 \| DAPK1 \| DHFR \| DMD \| DPYD \| EEF2 \| EGF \| EGFR \| ERBB2 \| ESR1 \| ETV4 \| EZR \| FADD \| FGF13 \| GDF15 \| HPSE \| HSP90AA1 \| IGF1 \| IL6 \| ITGB1 \| LCN2 \| MAPK1 \| MAPK3 \| MED28 \| MLH1 \| MMP2 \| MMP9 \| MTDH \| MYC \| NAGK \| NDRG1 \| NME1 \| NPPA \| OGN \| PIK3C2B \| PLAUR \| PMS2 \| PTEN \| PXN \| RB1 \| SERPINA1 \| SLC39A4 \| SLC39A6 \| SNAI1 \| SNAI2 \| SOD2 \| SPP1 \| SRSF1 \| STAT3 \| TBCB \| TGFB1 \| TNF \| TNFAIP8 \| TPM4 \| UCHL3 \| VEGFA \| VIM \| VIP \| YWHAE	32.46	69
19.	Thalidomide	Autistic Disorder	M	25 genes: AQP4 \| BCL2 \| CACNA1C \| CAT \| CDH10 \| GPX1 \| IFNG \| IGF1 \| IGFBP3 \| IL10 \| IL1RN \| IL2 \| IL4 \| IL5 \| IL6 \| NOS2 \| NRP2 \| PECAM1 \| PLAUR \| PRF1 \| PTEN \| PTGS2 \| SCN7A \| SERPINE1 \| TNFRSF1B	31.63	29
20.	Benzoic Acid	Arthritis, Experimental	M	9 genes: ALB \| CAT \| COL2A1 \| EGFR \| IL1RL1 \| IL6 \| MPO \| STAT3 \| VEGFA	31.39	16
21.	Puromycin Aminonucleoside	Nephrosis	M	10 genes: AGT \| ALB \| DES \| EDN1 \| EDNRB \| HPSE \| ICAM1 \| NPHS2 \| REN \| VIM	31.33	147
22.	Benzoyl Peroxide	Skin Neoplasms	M	9 genes: GJA1 \| GJB2 \| GJB5 \| HRAS \| IGF1 \| IL1A \| ODC1 \| PTGS2 \| TGFB1	31.19	31
23.	Diclofenac	Cardiomyopathies	M	25 genes: AKT1 \| AQP2 \| CAT \| CBR1 \| CYP2C9 \| EDN1 \| EPO \| FAS \| IL1A \| IL1B \| IL4 \| IL6 \| ITGB1 \| LDHA \| MAPK1 \| MAPK14 \| MAPK3 \| PARP1 \| PTGS2 \| SOD2 \| STAT3 \| TLR2 \| TNF \| TRP53 \| TXN1	30.64	26
24.	Diclofenac	Heart Failure	M	29 genes: ALB \| APCS \| CAT \| CRP \| CXCL2 \| EDN1 \| FASN \| GDF15 \| GSK3B \| HIF1A \| HMOX1 \| IFNG \| IL1B \| IL6 \| ITGB1 \| NFE2L2 \| NOS2 \| PCK1 \| PDPK1 \| PPARG \| PPARGC1A \| PTGS1 \| PTGS2 \| SERPINE1 \| SOD2 \| TNF \| TNFRSF1A \| TRP53 \| VEGFA	30.64	34
25.	Diethylhexyl Phthalate	Infertility, Female	M	20 genes: ADIPOR1 \| AR \| ARNTL \| CEBPA \| CYP17A1 \| CYP19A1 \| DHFR \| ESR1 \| ESR2 \| FSHB \| LEP \| LHB \| LIF \| MAPK1 \| MAPK3 \| NR1I2 \| NR2F2 \| NR5A2 \| PRL \| TP53	29.85	15
26.	Diclofenac	Acute Kidney Injury	M	33 genes: ALB \| ATP5B \| BAX \| CLU \| CYP2C19 \| CYP2C9 \| CYP2D6 \| CYP3A23/3A1 \| EDN1 \| EPO \| GSK3B \| GSTM2 \| GSTP1 \| HAVCR1 \| HBEGF \| HMOX1 \| HSPA1A \| IGFBP1 \| IL10 \| IL6 \| KLK1 \| KNG1 \| LCN2 \| MPO \| NFE2L2 \| NOS2 \| NQO1 \| PPARG \| TNF \| TP53 \| UGT1A1 \| UGT1A9 \| VEGFA	29.27	48
27.	Puromycin Aminonucleoside	Kidney Failure, Chronic	M	12 genes: ACE \| ALB \| CAT \| CCL2 \| GUCA2B \| HBEGF \| HMGCR \| HMOX1 \| PTGS2 \| SERPINE1 \| TGFB1 \| TNF	29.10	12
28.	Diethylhexyl Phthalate	Insulin Resistance	M	31 genes: ACACB \| ADIPOQ \| AHR \| AR \| C3 \| CD36 \| EGFR \| GNAS \| HMOX1 \| HSD11B1 \| INS \| INS1 \| INSR \| IRS1 \| IRS2 \| LEP \| MC4R \| NOS3 \| NR4A1 \| NR4A3 \| PLTP \| PPARA \| PPARG \| PTEN \| SCD1 \| SELENOP \| SLC2A4 \| SOD2 \| SREBF1 \| STS \| TNF	28.75	41
29.	mono-(2-ethylhexyl)phthalate	Infertility, Female	M	14 genes: AR \| CEBPA \| CEBPB \| CTGF \| CYP17A1 \| CYP19A1 \| ESR1 \| FSHB \| LHB \| MAPK1 \| MAPK3 \| NR1I2 \| NR2F2 \| TP53	28.48	10
30.	Bezafibrate	Drug-Induced Liver Injury	M	32 genes: ABCB1 \| ABCC2 \| ADIPOQ \| AHR \| APOA1 \| APOE \| BAX \| CAT \| CCL2 \| FADS1 \| FADS2 \| FASN \| GSR \| HADHA \| IFNG \| IGF1 \| IL18 \| IL1B \| IL6 \| LGALS3 \| NOX4 \| NR1H3 \| NR1H4 \| NR1I2 \| NR1I3 \| PCYT1A \| PDK4 \| PPARA \| SOD1 \| SPP1 \| TNF \| UGT1A9	28.34	32
31.	Puromycin Aminonucleoside	Acute Kidney Injury	M	19 genes: ALB \| AVP \| BAX \| CD44 \| EDN1 \| GSK3B \| GSTP1 \| HBEGF \| HMOX1 \| LCN2 \| NOS2 \| NOS3 \| NPPA \| PPARG \| SPP1 \| TGFB1 \| TNF \| TP53 \| VEGFA	27.72	27
32.	methylparaben	Infertility, Female	M	6 genes: CYP19A1 \| ESR1 \| ESR2 \| LEP \| MAPK1 \| MAPK3	27.66	5
33.	Bezafibrate	Cholestasis	M	18 genes: ABCB11 \| ABCC2 \| AGT \| CAT \| CXCL8 \| CYP4A14 \| CYP7A1 \| ICAM1 \| IGF1 \| IL6 \| NR1H2 \| NR1H3 \| NR1H4 \| POMC \| RELA \| SERPINE1 \| TNF \| VCAM1	27.52	15
34.	Diclofenac	Myocardial Infarction	M	28 genes: BAX \| BCL2L1 \| CASP3 \| CAT \| DDIT3 \| EPO \| GATA4 \| GCLC \| GCLM \| GGT1 \| GSK3B \| HMGB1 \| HSPA5 \| ICAM1 \| IL10 \| IL1B \| IL1RN \| IL6 \| ITGB3 \| KLK1 \| LDHA \| NOS2 \| PLAU \| PPARGC1A \| SELL \| SOD2 \| TNF \| TRP53	27.11	38
35.	Puromycin Aminonucleoside	Glomerulonephritis	M	11 genes: AGT \| ALB \| CCL1 \| CCL2 \| CCL3 \| CCL7 \| DES \| IL1B \| NPHS1 \| PPARG \| TNF	26.78	16
36.	diethyl phthalate	Fatty Liver	M	10 genes: APOB \| CAT \| CXCL8 \| CYP19A1 \| GPT \| GPX1 \| NR1I2 \| PPARA \| SOD1 \| TNF	26.75	11
37.	Diethylhexyl Phthalate	Polycystic Ovary Syndrome	M	26 genes: BAX \| BCL2 \| CCNB1 \| CEP55 \| CKS2 \| CYP19A1 \| DACT3 \| DLG4 \| FSHR \| GDF9 \| GNAS \| HSD3B1 \| HSD3B2 \| INS \| ISYNA1 \| LEP \| LHB \| LIF \| LIFR \| NRG1 \| PNPLA2 \| SCNN1A \| SRD5A1 \| STAR \| TFRC \| UBE2H	26.45	13
38.	Puromycin Aminonucleoside	Disease Models, Animal	M	13 genes: ALB \| FAS \| HBEGF \| IL1B \| MAPK1 \| MAPK3 \| MAPK8 \| RHOA \| SERPINE1 \| TIMP1 \| TNF \| TRP53 \| VIM	26.22	23
39.	Phthalic Acids	Obesity	M	22 genes: ALDH1L1 \| ATPAF1 \| CPE \| CRP \| CYB5A \| ECHS1 \| ESR1 \| ETFDH \| FASN \| HMOX1 \| IGFBP2 \| ME1 \| MTCH2 \| NR1I3 \| PFKFB3 \| PPARG \| PRKAR2B \| SCD1 \| SLC22A1 \| SOD2 \| TFRC \| TNF	25.22	24
40.	mono-benzyl phthalate	Obesity	M	6 genes: CRP \| NR1I2 \| NR1I3 \| PPARA \| PPARD \| PPARG	25.21	7
41.	Diclofenac	Hypertension	M	40 genes: ABCC1 \| ALB \| ALOX15 \| CALCA \| CAT \| CBS \| CCL2 \| CRP \| CXCL2 \| CYP1A1 \| EDN1 \| EPO \| FOS \| GCLC \| GNAS \| GPX1 \| GSK3B \| GSTA5 \| GSTT1 \| HIF1A \| HMOX1 \| ICAM1 \| IKBKB \| IL1B \| IL6 \| JUN \| KLK1 \| KNG1 \| NOS2 \| NR3C1 \| PPARG \| PTEN \| PTGS2 \| RELA \| SELP \| SERPINE1 \| SOD2 \| TIMP1 \| TNF \| TP53	24.88	56
42.	Puromycin Aminonucleoside	Proteinuria	M	14 genes: AGT \| ALB \| APOE \| CTSB \| CTSL \| FAS \| NPHS1 \| PTGS2 \| REN \| RHOA \| SCNN1A \| SPP1 \| TGFB1 \| VEGFA	24.33	173
43.	phthalic anhydride	Respiratory Hypersensitivity	M	5 genes: CCL11 \| CCR3 \| IL4 \| IL6 \| TNF	24.09	5
44.	Puromycin Aminonucleoside	Nephrotic Syndrome	M	10 genes: ALB \| COL1A1 \| COL4A1 \| GUCA2B \| HSD11B2 \| NPHS2 \| SERPINE1 \| SOD2 \| TF \| TGFB1	23.90	81
45.	diethyl phthalate	Drug-Induced Liver Injury	M	14 genes: AHR \| APOA1 \| BAX \| CAT \| CYP2C11 \| GOT1 \| GPT \| GSR \| IGF1 \| NR1I2 \| NR1I3 \| PPARA \| SOD1 \| TNF	23.12	22
46.	Diethylhexyl Phthalate	Liver Neoplasms	M	40 genes: ABCB1B \| ACOT1 \| AHR \| ANXA7 \| APCS \| ATF3 \| BAP1 \| CCND1 \| CDKN2A \| CPT1B \| CSF2 \| CTNNB1 \| DPP10 \| ESR1 \| FOSB \| FST \| GSTM1 \| HIGD2A \| HMOX1 \| HRAS \| HSDL2 \| IGF2 \| JUN \| MIR29A \| MYC \| NDRG1 \| NFE2L2 \| NR1I3 \| PPARA \| PPARG \| PSMA4 \| PTER \| SCD \| SERPINE1 \| SLC2A1 \| SNHG11 \| TNF \| TP53 \| UGDH \| XPC	22.55	41
47.	Dibutyl Phthalate	Weight Loss	M	3 genes: ADORA2A \| SOD1 \| TSC22D3	22.43	4
48.	phthalic anhydride	Asthma	M	6 genes: CCL11 \| CCL2 \| IL13 \| IL4 \| IL5 \| TNF	21.67	12
49.	Puromycin Aminonucleoside	Kidney Diseases	M	18 genes: ACE \| AGT \| ALB \| CDKN1A \| CTSD \| EDN1 \| GSTP1 \| LCN2 \| NOS2 \| NPHS1 \| NPR1 \| PTGS2 \| REN \| SLC12A3 \| SLC22A2 \| SOD2 \| SPP1 \| TGFB1	21.49	64
50.	Thalidomide	Disease Models, Animal	M	17 genes: AKT1 \| FAS \| FOS \| HCN1 \| IFNG \| IL1B \| MAPK1 \| MAPK3 \| MMP9 \| MYBPC3 \| PIM1 \| RHOA \| SERPINE1 \| SOD1 \| STAT3 \| TIMP1 \| TNF	21.41	17

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