Hydrocarbons, Acyclic - Diseases

These diseases are associated with Hydrocarbons, Acyclic or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 57,023 results.

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	Chemical	Disease	Direct Evidence	Inference Network	Inference Score	References
1.	Capsaicin	Diabetes Mellitus, Experimental	M	56 genes: ACOX1 \| AIFM1 \| ATF3 \| ATP2A2 \| BAX \| BCL2 \| BCL2L1 \| BDKRB1 \| CASP3 \| CAT \| CCL20 \| CD68 \| CPT1A \| CX3CL1 \| CYBB \| CYP1A1 \| EDN1 \| FAS \| GPX1 \| GSR \| HMOX1 \| ICAM1 \| IFNG \| IGF1 \| IL1B \| IL6 \| INS1 \| IRS1 \| LEP \| MMP2 \| MMP9 \| MPO \| NOS2 \| NOS3 \| NQO1 \| PDX1 \| PPARA \| PPARG \| PPARGC1A \| PRKCA \| PRKCD \| PRKCE \| PTGS2 \| RELA \| SERPINE1 \| SLC2A4 \| SOD2 \| TGFB1 \| TIMP1 \| TIMP2 \| TNF \| TNFRSF1A \| TP53 \| TRP53 \| UCP2 \| VEGFA	138.27	44
2.	Tretinoin	Craniofacial Abnormalities	M	106 genes: ACTB \| ACTG1 \| ALX1 \| ANKH \| ANXA1 \| ATRX \| B3GAT3 \| BMPR1A \| BMPR1B \| BNC2 \| CHST14 \| CNTN4 \| COL11A1 \| COL11A2 \| COL2A1 \| COLEC11 \| CTNNB1 \| DLL3 \| DLX1 \| DLX2 \| DLX5 \| DLX6 \| DNMT3A \| DNMT3B \| ECE1 \| EDN1 \| EDNRA \| EGFR \| EP300 \| ERF \| EYA1 \| FADD \| FGF3 \| FGF8 \| FGFR1 \| FGFR2 \| FOLR1 \| FOXC2 \| FOXP2 \| FZD4 \| GABRB3 \| GATA2 \| GNAQ \| GPC6 \| GSC \| HAPLN1 \| HOXA1 \| HOXA3 \| HOXB1 \| HSPG2 \| IRF6 \| ITGB1BP1 \| LPAR1 \| LTBP3 \| MBTPS1 \| MMP13 \| MMP2 \| MNT \| MSX1 \| MSX2 \| NDST1 \| NIPBL \| NOTCH1 \| NRXN1 \| PAX3 \| PAX6 \| PBX4 \| PDGFRA \| PHEX \| PITX2 \| PTCH1 \| PTEN \| RAB39B \| RAD23B \| RAI1 \| RAX \| RCAN1 \| RDH10 \| RUNX2 \| SALL3 \| SALL4 \| SIN3A \| SIX1 \| SKI \| SLC26A2 \| SMAD2 \| SMAD3 \| SMAD4 \| SOX9 \| SOX9A \| SPRY2 \| STRA6 \| SURF1 \| TBX1 \| TBX15 \| TCF4 \| TCOF1 \| TFAP2A \| TFAP2B \| TGFB2 \| TGFBR2 \| TRP53 \| TRPS1 \| UBE3A \| ZIC3 \| ZIC5	113.01	134
3.	Capsaicin	Stomach Neoplasms	M	50 genes: AHR \| ALB \| ALOX5 \| AREG \| ATM \| BCL2L1 \| BDNF \| BID \| BIRC2 \| BIRC5 \| BNIP3 \| CASP8 \| CCND1 \| CDK4 \| CDKN1A \| CDKN1B \| CDKN2A \| CHEK2 \| CXCL8 \| EGFR \| ERBB2 \| GADD45A \| GAST \| GSTP1 \| HBEGF \| HMOX1 \| HRAS \| IL1B \| IL1RN \| IL6 \| ITGA5 \| JUN \| MAPK1 \| MAPK3 \| MAPK8 \| MYC \| NOS3 \| PLAU \| PLIN2 \| PPARG \| PRKAA1 \| PTGS2 \| RXRB \| SERPINE1 \| SOD2 \| STAT3 \| TGFA \| TIMP3 \| TNF \| TP53	84.90	47
4.	perfluorooctane sulfonic acid	Breast Neoplasms	M	106 genes: ABCB1 \| ABCC1 \| ABCG2 \| ACHE \| AHR \| AKT1 \| ALDOA \| ANGPTL4 \| APRT \| AR \| BAX \| BCHE \| BCL2 \| BIRC2 \| BMP4 \| BMPR2 \| CAT \| CCL20 \| CCND1 \| CDH1 \| CFL1 \| CLDN1 \| CPT1A \| CXCL8 \| CXCR4 \| CYP17A1 \| CYP19A1 \| CYP1A1 \| CYP2B1 \| CYP2D6 \| CYP3A4 \| DIO3 \| DKK1 \| DNMT3A \| EFNA1 \| EGFR \| ENO1 \| ERBB2 \| ESR1 \| ESR2 \| EXO1 \| EZH2 \| FABP7 \| FASN \| FLT1 \| FOS \| GPX1 \| GPX2 \| GSTP1 \| HADHB \| HES1 \| HHEX \| HMOX1 \| HP \| HSP90AA1 \| IFNG \| IL1B \| IL6 \| ITSN2 \| JUN \| KDR \| LEP \| LPAR1 \| LSP1 \| MEIS1 \| MIR145 \| MIR200C \| MIR206 \| MIR345 \| MME \| MMP14 \| MMP2 \| MMP9 \| NAT2 \| NCOR1 \| NOS2 \| NOS3 \| NQO1 \| NRIP1 \| OCLN \| PARP1 \| PDE2A \| PGR \| PHB \| PPARGC1B \| PTGS2 \| PTPRD \| RARA \| RB1CC1 \| RECQL \| RELA \| RGS2 \| RRAD \| SERPINB5 \| SLC2A2 \| SLC5A5 \| SLCO1B1 \| SOD2 \| SPP1 \| TNF \| TNFSF10 \| TP53 \| TRP53 \| TRP63 \| ZEB1 \| ZEB2	83.23	161
5.	Vitamin A	Liver Cirrhosis, Experimental	M	47 genes: ABCB1 \| ABCB1A \| ACTA2 \| ADH1 \| ADH4 \| AFP \| AKR1B1 \| ALB \| ALDH1A1 \| APP \| CASP7 \| CCL2 \| COL1A1 \| COL4A2 \| CYP26A1 \| CYP2C11 \| DHRS3 \| FOXA2 \| G6PC \| GH1 \| GJA1 \| GNAI2 \| GPT \| HOXA3 \| IFNG \| IL1B \| INS \| ITGB1 \| JAK2 \| KRT18 \| KRT19 \| KRT8 \| LEP \| LRAT \| MYC \| NOS2 \| NOS3 \| PCK1 \| POMC \| PTGS2 \| RARRES1 \| RDH10 \| TGFB3 \| TGFBR2 \| TLR4 \| TNF \| VEGFA	71.29	30
6.	Taurocholic Acid	Cholestasis	M	22 genes: ABCB11 \| ABCC2 \| ABCC3 \| BLVRA \| CCL7 \| CXCL2 \| CYP27A1 \| CYP7A1 \| CYP7B1 \| EGR1 \| ICAM1 \| IL6 \| NOS2 \| NR1H4 \| PON1 \| RELA \| SLC23A1 \| SLC23A2 \| SLCO1A1 \| SLCO1A4 \| TNF \| VCAM1	61.65	17
7.	Chloroprene	Breast Neoplasms	M	77 genes: ABCC1 \| ABCG2 \| ADAMTS1 \| AFP \| AGR2 \| AKAP12 \| ANGPTL4 \| AR \| ARRDC3 \| ATP7B \| AURKA \| BCAR3 \| BCL2 \| BMPR2 \| CCL20 \| CD40 \| CLDN4 \| CXCL12 \| CXCL3 \| CXCR4 \| CYP1A1 \| CYP1B1 \| DNMT3A \| EDNRB \| EGFR \| EMSY \| ETV4 \| EVL \| F3 \| FLT1 \| FN1 \| FOS \| FOXQ1 \| FST \| GPX2 \| H2AFX \| HIC1 \| HMOX1 \| HNRNPL \| HRAS \| HSPA1B \| IGF1 \| IGFBP5 \| IL1B \| ITSN2 \| JUN \| KRAS \| LIMD2 \| LOXL2 \| LPAR1 \| LSP1 \| MAL \| MDM2 \| MMP9 \| NCOR1 \| NQO1 \| NRCAM \| PABPC1 \| PER3 \| PTHLH \| PTPRD \| RB1CC1 \| RBM3 \| RGS2 \| RRAD \| SLC2A1 \| SNAI2 \| SPP1 \| STAT3 \| TFPI2 \| THBS1 \| THEMIS2 \| TNF \| TNFSF10 \| UBE2C \| WT1 \| ZEB2	53.84	79
8.	Capsaicin	Myocardial Infarction	M	33 genes: APOE \| ATM \| BAX \| BCL2 \| BCL2L1 \| BECN1 \| CASP3 \| CAT \| CREB1 \| DDIT3 \| F2 \| GSK3B \| HSP27 \| HSPA5 \| ICAM1 \| IL10 \| IL1B \| IL1RN \| IL6 \| MMP2 \| MMP9 \| NOS2 \| NOS3 \| PLAU \| PPARGC1A \| PRKCE \| S100B \| SELL \| SOD2 \| TGFB1 \| TIMP2 \| TNF \| TRP53	41.60	31
9.	Capsaicin	Cardiomegaly	M	26 genes: ADRA2A \| AGTR1A \| AHR \| AKT1 \| ATP2A2 \| CYP1A1 \| CYP2E1 \| EDN1 \| FGF2 \| GSK3B \| HDAC2 \| HIF1A \| HMOX1 \| IGF1 \| IL1B \| NOS3 \| POMC \| PPARA \| PPARD \| PRKCA \| SLC2A4 \| SOD2 \| SRC \| STAT3 \| TNF \| UCP2	41.20	35
10.	Isotretinoin	Abortion, Spontaneous	M	25 genes: AGTR1 \| APOE \| CD69 \| CEACAM1 \| CEACAM5 \| COL1A1 \| COL5A1 \| COL5A2 \| COL6A1 \| COL6A3 \| CXCL10 \| DHFR \| EMP1 \| FN1 \| IFI35 \| IGF1 \| IGFBP3 \| IL1B \| IL24 \| IL6 \| SDF2L1 \| TFRC \| TGFB1 \| TIMP3 \| TNFSF10	41.06	3
11.	fumonisin B1	Drug-Induced Liver Injury	M	41 genes: ABCB1 \| AHR \| ALDOB \| ANXA2 \| BAX \| CAR3 \| CAT \| CCL2 \| CLU \| CP \| CTNNB1 \| CXCL1 \| CYP2E1 \| CYP8B1 \| EPHX1 \| FMO3 \| GSTM1 \| GSTM2 \| GSTM3 \| HMOX1 \| HPX \| IFNG \| IGF1 \| IL1A \| IL1B \| IL6 \| KRT18 \| MIR27B \| NFE2L2 \| NR1I3 \| PON1 \| PPARA \| PZP \| RGN \| S100A11 \| SERPINA6 \| SERPING1 \| SOD1 \| TAGLN2 \| TNF \| TTR	39.20	43
12.	Capsaicin	Disease Models, Animal	M	23 genes: AKT1 \| ALB \| CALCA \| ERBB2 \| FAS \| FOS \| GFAP \| GRIN1 \| HBEGF \| IFNG \| IL1B \| MAPK1 \| MAPK3 \| MAPK8 \| MAPK9 \| MMP9 \| S100B \| SERPINE1 \| STAT3 \| TIMP1 \| TNF \| TRP53 \| VIM	36.48	17
13.	Capsaicin	Urinary Bladder Neoplasms	M	25 genes: ATM \| CDKN1A \| CDKN2A \| CXCL8 \| EGFR \| ENO2 \| FAS \| GPX1 \| GSTP1 \| HRAS \| IGF1 \| IL2 \| MPO \| MYC \| NQO1 \| POLB \| POR \| PTGS2 \| RB1 \| SOD2 \| SRC \| TNF \| TP53 \| TRP53 \| TRPV1	35.82	38
14.	Vitamin A	Carcinoma, Hepatocellular	M	23 genes: ABCB1 \| ACTB \| AFP \| AKR1B10 \| BTG2 \| CCND1 \| CTNNB1 \| CYP1A1 \| CYP2E1 \| EGFR \| ESR1 \| GSTP1 \| MPO \| MYC \| PCK1 \| PPARG \| PTGS2 \| RARA \| SHH \| SOD2 \| TGFA \| TLR4 \| TNF	35.05	28
15.	hexachlorobutadiene	Drug-Induced Liver Injury	M	16 genes: ALB \| CCL2 \| CLU \| EPHX1 \| GCLC \| GSR \| GSTM1 \| GSTM4 \| HAVCR1 \| HMOX1 \| IL1B \| KNG1 \| LCN2 \| MMP2 \| RGN \| SPP1	34.74	17
16.	Taurocholic Acid	Neoplasm Invasiveness	M	14 genes: CCL2 \| CCL5 \| EGFR \| HGF \| IL1B \| IL6 \| MAPK1 \| MAPK3 \| MMP2 \| MMP9 \| RELA \| S1PR2 \| SOD2 \| TNF	34.59	29
17.	Taurocholic Acid	Drug-Induced Liver Injury	M	22 genes: ABCB1 \| ABCC1 \| ABCC2 \| APOA1 \| CCL2 \| CSF3 \| CXCL1 \| CXCL10 \| CYP2C11 \| IL1B \| IL6 \| MAP1LC3B \| MMP2 \| NR1H4 \| NR1I2 \| NR1I3 \| PON1 \| PTGS2 \| SLC22A8 \| SOD1 \| SOD2 \| TNF	34.50	24
18.	Capsaicin	Nerve Degeneration	M	28 genes: APOE \| BAK1 \| BAX \| BCL2 \| BDNF \| CASP3 \| CNR1 \| CNTF \| CTNNB1 \| EIF2S1 \| EPOR \| F2 \| FGF2 \| GHRL \| IFNG \| IGF1 \| IGF2 \| LEP \| MAPK1 \| MAPK3 \| NGF \| NGFR \| NOS1 \| PPARG \| SOD2 \| TGFA \| TH \| TNF	34.28	35
19.	Capsaicin	Hypersensitivity	M	20 genes: ALB \| CCL19 \| CCL2 \| CCL20 \| CCL3 \| CX3CL1 \| CXCL5 \| CYP1A1 \| IFNG \| IL13 \| IL1B \| IL4 \| IL6 \| IL6ST \| KNG1 \| SPP1 \| TAC1 \| TGFB1 \| TNF \| TNFRSF1A	33.82	9
20.	Capsaicin	Skin Neoplasms	M	21 genes: AKT1 \| CASP8 \| CEBPA \| CSNK2A1 \| CSNK2B \| GYPA \| HIF1A \| HRAS \| IGF1 \| IGF1R \| IL1A \| MMP9 \| NFE2L2 \| PPARD \| PTGS2 \| RELA \| SOD2 \| SP1 \| TGFB1 \| TP53 \| TRP53	33.31	27
21.	Capsaicin	Pneumonia	M	21 genes: AHR \| CCL19 \| CCL2 \| CCL20 \| CSF2 \| CX3CL1 \| CXCL5 \| HMOX1 \| IFNG \| IL13 \| IL1B \| IL4 \| IL6 \| IL6ST \| PARP1 \| POMC \| SPP1 \| TGFB1 \| TLR4 \| TNF \| TNFRSF1A	32.41	8
22.	Tretinoin	Nausea	M	6 genes: ABCB1 \| IFNG \| OPRM1 \| POMC \| TNF \| TNFRSF10A	32.17	10
23.	vinylidene chloride	Carcinoma	M	35 genes: ACSL1 \| ANXA1 \| AQP1 \| BASP1 \| BRCA1 \| CDS1 \| CORO1A \| EFEMP1 \| EPCAM \| EPHX1 \| ESR1 \| FN1 \| GATA3 \| GATM \| GDA \| ID4 \| KRAS \| LIN7A \| LPL \| MERTK \| MET \| MYC \| NDN \| PLK2 \| PPARA \| PRLR \| RASGRF2 \| RCN1 \| S100A6 \| SLC25A10 \| SOD2 \| SOX9 \| TSC22D1 \| UCP2 \| XDH	32.09	17
24.	Tretinoin	Vomiting	M	2 genes: ABCB1 \| IFNG	32.01	4
25.	perfluorooctane sulfonic acid	Fatty Liver	M	40 genes: APOB \| BIRC3 \| CAT \| CES1G \| CNDP2 \| CXCL8 \| CYP19A1 \| CYP2E1 \| CYP7B1 \| F2 \| F2R \| GPT \| GPX1 \| GULO \| HADHB \| HHEX \| INS \| LEP \| MIR134 \| MIR150 \| MIR17 \| MIR542 \| MTTP \| NR1H3 \| NR1I2 \| PLIN2 \| POMC \| PPARA \| PPARD \| PSMA5 \| SCD1 \| SERPINA6 \| SERPINE1 \| SLC2A2 \| SOD1 \| SOD2 \| SREBF1 \| TF \| TNF \| UCP2	31.92	35
26.	Chloroprene	Stomach Neoplasms	M	41 genes: AFP \| BCL2L1 \| BDNF \| BLVRB \| CDH2 \| CDKN1A \| CTSC \| DLC1 \| EGFR \| FAT4 \| FST \| HMOX1 \| HNRNPL \| HOXA2 \| HRAS \| HSPA8 \| HSPB1 \| ID4 \| IGFBP3 \| IL1B \| IRF1 \| ITGA8 \| JUN \| KLF6 \| KRAS \| LRRC3B \| MAPK8 \| MLF1 \| MSLN \| MTSS1 \| PLIN2 \| PRKCB \| PYCARD \| RGS2 \| RNF43 \| RORA \| SELENBP1 \| STAT3 \| TNF \| TNFSF9 \| ZBTB20	31.88	31
27.	Capsaicin	Trigeminal Neuralgia	M	10 genes: CALCA \| FOS \| GFAP \| GRIN1 \| IL1B \| MAPK1 \| MAPK3 \| MAPK8 \| MAPK9 \| TNF	31.29	2
28.	Tretinoin	Headache	M	2 genes: CSF3 \| IL6	30.56	16
29.	Chloroprene	Mammary Neoplasms, Experimental	M	32 genes: ABCG2 \| AFP \| AURKA \| COL5A1 \| EGFR \| EPHX1 \| FN1 \| G0S2 \| GATA3 \| GGT1 \| GSS \| HMOX1 \| HNRNPA1 \| HRAS \| ID4 \| IGF1 \| KITLG \| MMP9 \| MPZL1 \| MRC2 \| PLK2 \| RCN1 \| SCD \| SPP1 \| STAT3 \| TNFSF10 \| TRPS1 \| TUBB2B \| UCP2 \| XDH \| XIAP \| YWHAZ	28.71	19
30.	hexachlorobutadiene	Acute Kidney Injury	M	11 genes: ALB \| B2M \| CLU \| CST3 \| GPNMB \| HAVCR1 \| HMOX1 \| KNG1 \| LCN2 \| NQO1 \| SPP1	28.52	20
31.	Capsaicin	Dermatitis, Contact	M	17 genes: AHR \| BCL2 \| CASP8 \| CLDN1 \| CYP1A1 \| DDIT3 \| DUSP1 \| FABP4 \| GSR \| GSTP1 \| HMOX1 \| NQO1 \| NQO2 \| PRDX6 \| TLR4 \| UGT1A1 \| VEGFA	27.51	4
32.	Vitamin A	Disease Models, Animal	M	15 genes: AKT1 \| ALB \| APP \| ESR1 \| FAS \| HBEGF \| IFNG \| IL1B \| MAPK1 \| MAPK3 \| RHOA \| SNCA \| SOD1 \| STAT3 \| TNF	27.51	23
33.	Vitamin A	Inflammation	M	23 genes: AGER \| AHR \| AKT1 \| CCL2 \| COL2A1 \| EPO \| IFNG \| IL1B \| JAK2 \| LEP \| MPO \| NOS2 \| PPARA \| PPARG \| PTGS2 \| SOD1 \| STAT3 \| TFRC \| TGFA \| TLR2 \| TLR4 \| TNF \| VEGFA	26.56	56
34.	1,3-butadiene	Lung Neoplasms	M	11 genes: CDKN1A \| CYP2E1 \| DNMT3A \| EPHX1 \| GSTM1 \| GSTT1 \| HMOX1 \| HRAS \| KRAS \| MPO \| XPC	26.56	53
35.	Chloroprene	Mammary Neoplasms, Animal	M	25 genes: COL5A1 \| CORO1A \| EGFR \| EPHX1 \| FN1 \| G0S2 \| GATA3 \| GGT1 \| GSS \| HNRNPA1 \| HRAS \| ID4 \| KITLG \| MPZL1 \| MRC2 \| PLK2 \| RCN1 \| S100A8 \| SCD \| STAT3 \| TRPS1 \| TUBB2B \| UCP2 \| XDH \| YWHAZ	26.02	8
36.	Taurocholic Acid	Disease Models, Animal	M	10 genes: ABCB4 \| AKT1 \| IL1B \| KL \| MAPK1 \| MAPK3 \| MMP9 \| SOD1 \| STAT3 \| TNF	25.39	13
37.	Vitamin A	Craniofacial Abnormalities	M	14 genes: ACTB \| COL2A1 \| CTNNB1 \| EGFR \| GABRB3 \| HOXA1 \| HOXA3 \| LRP2 \| PAX3 \| RDH10 \| RUNX2 \| SOX9 \| STRA6 \| TGFBR2	25.25	17
38.	Retinaldehyde	Liver Cirrhosis, Experimental	M	12 genes: ADH1 \| ADH4 \| AKR1B1 \| AKR1C3 \| ALB \| ALDH1A1 \| ALDH2 \| CYP26A1 \| DHRS3 \| HMOX1 \| NFE2L2 \| RDH10	25.08	10
39.	tauromuricholic acid	Cholestasis	M	6 genes: ABCB11 \| ABCC2 \| ABCC3 \| CXCL2 \| ICAM1 \| SLCO1A1	24.71	7
40.	anandamide	Hypertension	M	11 genes: CD36 \| FOS \| IGF1 \| IL1B \| LEP \| MMP9 \| NOS2 \| PPARA \| PTGS2 \| TIMP1 \| TNF	23.00	21
41.	hexachlorobutadiene	Kidney Diseases	M	10 genes: ALB \| B2M \| CLU \| CST3 \| CYP3A5 \| HAVCR1 \| LCN2 \| NQO1 \| RGN \| SPP1	22.62	34
42.	Vinyl Chloride	Carcinoma, Hepatocellular	M	14 genes: ACLY \| CDKN2A \| CYP2E1 \| GSTM1 \| GSTP1 \| IL6 \| KRAS \| ME1 \| MED1 \| MTOR \| PCK1 \| SOCS3 \| SREBF1 \| TP53	22.54	24
43.	Vitamin A	Fatty Liver	M	15 genes: CAT \| CYCS \| CYP2E1 \| FOXA1 \| GPT \| GPX1 \| INS \| LEP \| MYC \| POMC \| PPARA \| SOD1 \| SOD2 \| TLR4 \| TNF	22.26	18
44.	Isotretinoin	Drug-Induced Liver Injury	M	52 genes: ABCB1 \| AIFM1 \| ALB \| APOE \| ATP6V1D \| BAX \| BDH1 \| BTD \| C3 \| CAT \| CCL2 \| COL14A1 \| COL3A1 \| CXCL1 \| CXCL10 \| DHFR \| DSC2 \| ECHDC1 \| FADS1 \| FADS2 \| FASN \| GSR \| GSTM1 \| GSTP1 \| HAO2 \| HLA-DQB1 \| IFNA2 \| IGF1 \| IL1A \| IL1B \| IL1R2 \| IL4 \| IL6 \| LCN2 \| LRAT \| MDH1 \| MMP2 \| NR1H4 \| NR1I2 \| NR1I3 \| PCOLCE \| PEX11A \| PLAT \| PTGS2 \| SERPING1 \| SOD2 \| SORD \| SPP1 \| TALDO1 \| TMEM164 \| TNF \| WASL	21.89	41
45.	Vinyl Chloride	Lung Neoplasms	M	14 genes: AKT1 \| CDKN2A \| CYP2E1 \| GSTM1 \| GSTP1 \| GSTT1 \| HMOX1 \| IL10 \| IL1B \| IL6 \| KRAS \| NOS2 \| TP53 \| XPC	21.82	59
46.	Tretinoin	Bradycardia	M	13 genes: AGT \| CHRM2 \| CYP1A1 \| CYP2D6 \| DRD2 \| EDN1 \| EDN2 \| EDN3 \| GCG \| LHB \| PDYN \| POMC \| TRH	20.10	21
47.	Capsaicin	Neurogenic Inflammation	M	8 genes: AMN \| CALCA \| NGF \| POMC \| PTGS2 \| TAC1 \| TACR1 \| TNF	19.23	27
48.	Tretinoin	Diarrhea	M	6 genes: CD14 \| CSF3 \| IL1A \| IL1RN \| LTF \| MYO5B	19.20	7
49.	Tretinoin	Cleft Palate	M	29 genes: BNC2 \| CASK \| COL2A1 \| EGF \| FGF10 \| FGF2 \| FGF3 \| FGF8 \| FGF9 \| FGFR1 \| FGFR2 \| FGFR3 \| FZD4 \| IRF6 \| MNT \| MSX1 \| MYC \| NEDD4L \| NOS3 \| PDGFRA \| PTCH1 \| RARG \| SLC19A1 \| SPRY2 \| SUMO1 \| TGFB1 \| TGFB2 \| TGFB3 \| TYMS	19.18	27
50.	Vinyl Chloride	Micronuclei, Chromosome-Defective	M	9 genes: CDKN2A \| CYP2E1 \| ERCC4 \| GSTM1 \| GSTT1 \| MGMT \| XPA \| XPC \| XRCC1	19.18	9

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