| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | ESR1 | 1,690 | 40 |
| 2. | ESR2 | 763 | 21 |
| 3. | AR | 460 | 8 |
| 4. | PGR | 376 | 9 |
| 5. | EGF | 319 | 4 |
| 6. | MAPK1 | 242 | 5 |
| 7. | TFF1 | 241 | 2 |
| 8. | MAPK3 | 231 | 5 |
| 9. | CCND1 | 167 | 4 |
| 10. | FSHB | 149 | 10 |
| 11. | TNF | 149 | 4 |
| 12. | PRL | 145 | 7 |
| 13. | IGF1 | 133 | 11 |
| 14. | CYP1A1 | 125 | 6 |
| 15. | FOS | 123 | 8 |
| 16. | KLK3 | 104 | 1 |
| 17. | CTSD | 100 | 3 |
| 18. | IL6 | 99 | 4 |
| 19. | MYC | 88 | 3 |
| 20. | AHR | 86 | 4 |
| 21. | BCL2 | 82 | 3 |
| 22. | IGF1R | 82 | 5 |
| 23. | NOS3 | 77 | 7 |
| 24. | SLC22A8 | 77 | 4 |
| 25. | NR3C1 | 76 | 7 |
| 26. | CASP3 | 75 | 3 |
| 27. | VEGFA | 74 | 6 |
| 28. | LHB | 73 | 9 |
| 29. | CYP19A1 | 72 | 7 |
| 30. | CYP1B1 | 71 | 3 |
| 31. | CDKN1A | 69 | 4 |
| 32. | AKT1 | 67 | 6 |
| 33. | PTGS2 | 66 | 7 |
| 34. | NDRG1 | 62 | 1 |
| 35. | BRCA1 | 61 | 2 |
| 36. | S100G | 61 | 3 |
| 37. | ABCC2 | 60 | 5 |
| 38. | GREB1 | 59 | 2 |
| 39. | IL1B | 59 | 5 |
| 40. | ABCG2 | 58 | 3 |
| 41. | NFE2L2 | 58 | 3 |
| 42. | VTG | 58 | 9 |
| 43. | CXCL12 | 55 | 2 |
| 44. | SOD2 | 53 | 3 |
| 45. | JUN | 52 | 4 |
| 46. | EGFR | 50 | 3 |
| 47. | SLCO1B1 | 50 | 1 |
| 48. | MMP9 | 47 | 5 |
| 49. | TGFB1 | 47 | 5 |
| 50. | CXCL8 | 43 | 2 |