| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | ESR1 | 1,946 | 43 |
| 2. | AR | 937 | 13 |
| 3. | ESR2 | 861 | 22 |
| 4. | PGR | 552 | 16 |
| 5. | FSHB | 423 | 13 |
| 6. | EGF | 349 | 4 |
| 7. | MAPK1 | 341 | 8 |
| 8. | MAPK3 | 324 | 7 |
| 9. | LHB | 315 | 15 |
| 10. | TNF | 273 | 6 |
| 11. | IGF1 | 264 | 15 |
| 12. | TFF1 | 263 | 3 |
| 13. | PRL | 235 | 9 |
| 14. | CYP19A1 | 233 | 13 |
| 15. | CCND1 | 215 | 5 |
| 16. | IL1B | 186 | 7 |
| 17. | IL6 | 184 | 6 |
| 18. | KLK3 | 184 | 1 |
| 19. | NR3C1 | 184 | 9 |
| 20. | FOS | 179 | 11 |
| 21. | CYP1A1 | 172 | 11 |
| 22. | THRB | 171 | 15 |
| 23. | CASP3 | 170 | 8 |
| 24. | BCL2 | 169 | 3 |
| 25. | CYP3A4 | 157 | 4 |
| 26. | PTGS2 | 143 | 12 |
| 27. | CGB3 | 136 | 4 |
| 28. | CYP17A1 | 134 | 13 |
| 29. | MYC | 127 | 4 |
| 30. | VEGFA | 122 | 8 |
| 31. | TGFB1 | 118 | 7 |
| 32. | NOS3 | 112 | 7 |
| 33. | HSD11B1 | 110 | 7 |
| 34. | CDKN1A | 109 | 5 |
| 35. | CYP11A1 | 109 | 11 |
| 36. | CYP1B1 | 109 | 4 |
| 37. | SOD2 | 108 | 6 |
| 38. | AKT1 | 107 | 8 |
| 39. | IGF1R | 107 | 7 |
| 40. | TTR | 105 | 10 |
| 41. | CTSD | 104 | 5 |
| 42. | PCNA | 104 | 7 |
| 43. | AGT | 102 | 10 |
| 44. | BAX | 102 | 4 |
| 45. | POMC | 102 | 14 |
| 46. | AHR | 101 | 6 |
| 47. | ABCC2 | 100 | 6 |
| 48. | NOS2 | 99 | 6 |
| 49. | STAR | 98 | 12 |
| 50. | NR1I3 | 93 | 6 |