| Interacting Gene | Interactions | Organisms | |
|---|---|---|---|
| 1. | ACHE | 428 | 18 |
| 2. | SLC22A2 | 277 | 4 |
| 3. | CASP3 | 152 | 5 |
| 4. | TNF | 117 | 5 |
| 5. | NFE2L2 | 111 | 3 |
| 6. | TGFB1 | 100 | 3 |
| 7. | CAT | 93 | 9 |
| 8. | HMOX1 | 93 | 3 |
| 9. | BAX | 81 | 3 |
| 10. | IL1B | 81 | 4 |
| 11. | SLC47A1 | 81 | 3 |
| 12. | SNCA | 74 | 3 |
| 13. | SLC22A3 | 68 | 2 |
| 14. | BCL2 | 66 | 3 |
| 15. | SOD2 | 64 | 6 |
| 16. | IL6 | 60 | 3 |
| 17. | SLC47A2 | 56 | 1 |
| 18. | SOD1 | 56 | 10 |
| 19. | SLC22A1 | 55 | 2 |
| 20. | TH | 49 | 4 |
| 21. | NOS2 | 47 | 3 |
| 22. | POR | 46 | 3 |
| 23. | NQO1 | 42 | 4 |
| 24. | GSR | 39 | 6 |
| 25. | MT1A | 39 | 3 |
| 26. | MPO | 38 | 3 |
| 27. | GPX1 | 37 | 4 |
| 28. | SLC6A3 | 35 | 3 |
| 29. | APOD | 34 | 2 |
| 30. | GSTA4 | 34 | 2 |
| 31. | MT2A | 34 | 2 |
| 32. | RELA | 34 | 4 |
| 33. | DDIT3 | 31 | 3 |
| 34. | MAPK1 | 29 | 3 |
| 35. | MAPK3 | 29 | 3 |
| 36. | TLR4 | 29 | 3 |
| 37. | CASP9 | 28 | 3 |
| 38. | BCHE | 27 | 4 |
| 39. | CTGF | 27 | 3 |
| 40. | CYP2E1 | 27 | 3 |
| 41. | AKT1 | 25 | 3 |
| 42. | LRRK2 | 24 | 2 |
| 43. | MMP9 | 24 | 3 |
| 44. | PARP1 | 24 | 3 |
| 45. | TP53 | 24 | 4 |
| 46. | IGF1 | 23 | 3 |
| 47. | TXN | 23 | 4 |
| 48. | HSPA5 | 22 | 3 |
| 49. | ACTA2 | 21 | 3 |
| 50. | IL4 | 21 | 2 |