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Illuminating how chemicals affect human health.
dexamethasone 21-tributylacetateThese diseases are associated with dexamethasone 21-tributylacetate. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).
| Disease | Direct Evidence | Enrichment Analysis | Inference Network | Inference Score | References | |
|---|---|---|---|---|---|---|
| 1. | Osteosarcoma | 2 genes: CYP3A4 | NR1I2 | 11.55 | 1 | ||
| 2. | Jaundice, Neonatal | 1 gene: NR1I2 | 6.32 | 1 | ||
| 3. | Gliosarcoma | 1 gene: CYP2B6 | 6.18 | 2 | ||
| 4. | TOBACCO ADDICTION, SUSCEPTIBILITY TO | 1 gene: CYP2B6 | 5.95 | 1 | ||
| 5. | Barrett Esophagus | 1 gene: NR1I2 | 5.52 | 1 | ||
| 6. | Hypophosphatemia | 1 gene: NR1I2 | 5.30 | 1 | ||
| 7. | Hepatitis C | 1 gene: CYP3A4 | 4.85 | 1 | ||
| 8. | Metabolic Syndrome X | 1 gene: NR1I2 | 4.85 | 1 | ||
| 9. | Infertility, Female | 1 gene: NR1I2 | 4.80 | 1 | ||
| 10. | Kidney Failure, Chronic | 1 gene: CYP2B6 | 4.79 | 1 | ||
| 11. | Esophageal Neoplasms | 1 gene: NR1I2 | 4.55 | 1 | ||
| 12. | Diabetes Mellitus | 1 gene: NR1I2 | 4.50 | 1 | ||
| 13. | Torsades de Pointes | 1 gene: CYP3A4 | 4.28 | 1 | ||
| 14. | Obesity | 1 gene: NR1I2 | 4.20 | 1 | ||
| 15. | Hepatomegaly | 1 gene: NR1I2 | 4.17 | 1 | ||
| 16. | Adenocarcinoma | 1 gene: NR1I2 | 4.16 | 1 | ||
| 17. | Fatty Liver | 1 gene: NR1I2 | 4.11 | 1 | ||
| 18. | Prostatic Neoplasms | 1 gene: CYP3A4 | 3.56 | 1 | ||
| 19. | Breast Neoplasms | 1 gene: CYP3A4 | 3.47 | 1 | ||
| 20. | Drug-Induced Liver Injury | 1 gene: NR1I2 | 3.43 | 2 |