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Disease Pathological Conditions, Signs and Symptoms

These are exposure studies associated with the disease and all of its children.

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301–350 of 358 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
301. Madrigano J, et al. (2010). Normative Aging Study (NAS) We examined the effect of PM exposure in a large cohort and found an association between BC and increases in sVCAM-1, which was greater in magnitude than that associated with a 1 year increase in age. disease Particulate Matter | Soot Subjects with gene influence:GSTM1 | Subjects with disease:Obesity | Study subjects United States Soot | VCAM1 Details gene expression
302. Baccarelli AA, et al. (2016). In this nationwide analysis of ~28 million individuals aged 55+ across 3,034 counties, higher levels of PM2.5 air pollution were associated with lower population-based probabilities of exceptional aging, even after adjusting for smoking, obesity, demographic and socioeconomic variables, total and age-specific migration rates, and differences across the nine census divisions of the U.S. body mass index | socioeconomic status | tobacco Particulate Matter | Tobacco Smoke Pollution Study subjects United States Particulate Matter Details Death
303. Steenland K, et al. (2010). C8 Health Project (C8HP) Higher serum levels of perfluorooctanoic acid were associated with a higher prevalence of hyperuricemia, but the limitations of cross-sectional data and the possibility of noncausal mechanisms prohibit conclusions regarding causality. perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid Details Hyperuricemia
304. Geiger SD, et al. (2013). National Health and Nutrition Examination Survey (NHANES) Our findings indicate that serum perfluoroalkyl chemical levels are significantly associated with hyperuricemia in children even at the lower 'background' exposure levels of the US general population. perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid Details Hyperuricemia
305. Shankar A, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our results demonstrate that elevated levels of perfluoroalkyl chemicals are associated with hyperuricemia even at low perfluoroalkyl chemical exposure levels as seen in a representative, multiethnic sample of US adults. perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum Uric Acid Details Hyperuricemia
306. Burns JS, et al. (2012). Russian Children's Study (RCS) Serum organochlorine pesticides concentrations measured at 8-9 years of age were associated with reduced growth, particularly reduced body mass index, during the peripubertal period, which may affect attainment of optimal adult body mass and height. body mass index Pesticides Children Russian Federation serum beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene Details Growth Disorders
307. Rinsky JL, et al. (2013). Agricultural Health Study (AHS) No measure of overall or specific pesticide use was positively associated with mortality due to stroke; further investigation of incident stroke, rather than stroke mortality, as well as stroke subtypes, is needed to determine the full role of agricultural exposures and stroke. Pesticides Workers United States Details Death | Stroke
308. Richardson JR, et al. (2014). Elevated serum dichlorodiphenyl dichloroethylene (DDE) levels are associated with an increased risk for Alzheimer disease, and APOE4 carriers may be more susceptible (as the allele modifies an association between DDE and scores); in vitro, both DDT and DDE increase amyloid precursor protein levels, providing mechanistic plausibility for the association. genetics Pesticides Controls for disease:Alzheimer Disease | Subjects with disease:Alzheimer Disease | Subjects with gene influence:APOE United States brain | serum Dichlorodiphenyl Dichloroethylene Details Alzheimer Disease | Disease Progression
309. Thomas HF, et al. (1996). A 15-year follow up of a group of pest control officers handling a wide range of pesticides did not show any significant risk of cancer. Pesticides Workers United Kingdom Details Death | Neoplasms
310. Rivero Osimani VL, et al. (2016). The impact of environmental organophosphate (OP) pesticide exposure on respiratory complexes, enzymatic antioxidant defense activities, and oxidative damage markers in the syncytiotrophoblast and cytotrophoblast mitochondria was evaluated. Pesticides Infants or newborns | Pregnant females Argentina Details Birth Weight | cytochrome-c oxidase activity | lipid oxidation | mitochondrial electron transport, cytochrome c to oxygen | progesterone biosynthetic process
311. Alves JS, et al. (2016). We observed changes in micronucleus genetic damage (influenced by PON1 polymorphism), superoxide dismutase activity, and levels of inorganic compounds in blood samples of agricultural workers exposed to complex mixtures of pesticides. genetics Pesticides Subjects with gene influence:PON1 | Study subjects | Workers Brazil blood Aluminum | Bromides | Chlorine | Iron | Magnesium | Phosphorus | Sulfur | Zinc Details Agricultural Workers' Diseases | Micronuclei, Chromosome-Defective | Organophosphate Poisoning | positive regulation of superoxide dismutase activity
312. Starks SE, et al. (2012). Agricultural Health Study (AHS) One or more high pesticide exposure events may contribute to adverse central nervous system outcomes independent of diagnosed pesticide poisoning. Pesticides Workers United States Details Agricultural Workers' Diseases | Neurobehavioral Manifestations | visual learning
313. Peres LC, et al. (2016). Women and Their Children's Health (WaTCH) Study Among southern Louisiana women, both physical-environmental and economic exposure to the Deepwater Horizon Oil Spill were associated with an increase in self-reported physical health outcomes. Petroleum Study subjects United States Details Dizziness | Eye Burns | Fatigue | Pharyngitis | Respiratory Sounds | Respiratory Tract Diseases
314. Lee CH, et al. (2010). We conducted a cross-sectional study of coastline residents exposed to heavily soaked contaminated areas of crude oil (from a tanker spill) and found significant increased risks of various acute physical symptoms (headache, nausea, dizziness, fatigue, hot flushing, sore throat, cough, runny nose, shortness of breath, itchy skin, rash, and sore eyes). Petroleum Study subjects Korea, Republic of Details Back Pain | Cough | Dizziness | Dyspnea | Exanthema | Eye Manifestations | Fatigue | Fever | Flushing | Headache | Myalgia | Nausea | Pharyngitis | Pruritus
315. Kponee KZ, et al. (2015). In this cross-sectional pilot study, the first carried out in response to the United Nations Environment Programme recommendations, we observed statistically significant associations between exposure to petroleum-contaminated drinking water and self-reported symptoms consistent with exposure to petroleum hydrocarbons. Petroleum | Water Pollutants, Chemical Study subjects Nigeria Details Anemia | Dermatitis, Irritant | Dizziness | Eye Pain | Headache | Pharyngitis
316. Wolff MS, et al. (2008). Children's Environmental Health Study We observed a range of phthalate and phenol exposures during pregnancy, but few were associated with birth size; the association of 2,5-dichlorophenol and benzophenone-3 with reduced or increased birth weight could be important in very early or small-size births. Phenols | Phthalic Acids Pregnant females United States urine 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | bisphenol A | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monomethyl phthalate | oxybenzone | Triclosan Details Birth Weight
317. Philippat C, et al. (2012). EDEN | PELAGIE We observed evidence of an inverse association of 2,5-dichlorophenol and a positive association of benzophenone-3 with male birth weight. sex Phenols | Phthalic Acids Pregnant females France urine 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | bisphenol A | butylparaben | ethyl-p-hydroxybenzoate | methylparaben | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | mono(carboxy-isooctyl)phthalate | monoethyl phthalate | mono-isobutyl phthalate | oxybenzone | propylparaben | Triclosan Details Birth Weight | Prenatal Exposure Delayed Effects | head development
318. Lind PM, et al. (2012). Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) The present evaluation shows that especially the phthalate metabolite mono-isobutyl phthalate was related to increased fat amount in the subcutaneous abdominal region in women measured by dual-energy X-ray absorptiometry and magnetic resonance imaging two years later. sex Phthalic Acids Study subjects Sweden diethyl phthalate | mono-(2-ethylhexyl)phthalate | mono-isobutyl phthalate | monomethyl phthalate Details Obesity | lipid biosynthetic process
319. Ramesh A, et al. (2015). We report concentrations of polycyclic aromatic hydrocarbons in human blood obtained at autopsy from individuals who died of drug abuse, alcohol toxicity, homicide, suicide and other unknown causes; the mean concentrations were greater in the 20-50 year age groups and higher levels were detected in African Americans (compared to Caucasians, Asians, and Hispanics). age | race Polycyclic Aromatic Hydrocarbons Children | Subjects with disease:Death United States serum Polycyclic Aromatic Hydrocarbons Details
320. Jedrychowski WA, et al. (2015). To our knowledge, this is the first epidemiologic study showing that prenatal polycyclic aromatic hydrocarbon (PAH) exposure measured by cord blood PAH-DNA adducts is associated with cognitive dysfunction (depressed verbal IQ index) assessed by the WISC-R test, which is the commonly used instrument for measuring intelligence of children. Polycyclic Aromatic Hydrocarbons Children Poland blood, cord polycyclic aromatic hydrocarbons-DNA adduct Details Cognition Disorders | Learning Disorders | cognition
321. Goto H, et al. (2012). Life Span Study We calculated the standardized mortality ratio (SMR) for the atomic bomb survivors versus the entire population of Japan in childhood and compared them with a true non-exposed group. A notable result was that SMRs in boys exposed to low doses were significantly higher for solid cancer. sex Radioactive Fallout Children Japan Radioactive Fallout Details Breast Neoplasms | Death | Leukemia | Liver Neoplasms | Neoplasms | Stomach Neoplasms | Uterine Neoplasms
322. Colvin L, et al. (2012). Children born to mothers using a selective serotonin reuptake inhibitor were more likely to be admitted to a hospital in the first years of life, and although the numbers of deaths in the first year of life were small, the increased risk is a new finding and should be investigated further. Serotonin Uptake Inhibitors Pregnant females Australia Details Death | Fetal Diseases
323. Hoppin JA, et al. (2004). Agricultural Health Study (AHS) Using the Agricultural Health Study, a cohort of pesticide applicators in Iowa and North Carolina, we evaluated the odds of wheeze associated with nonpesticide occupational exposures. Solvents | Vehicle Emissions Workers United States Details Respiratory Sounds
324. Li Y, et al. (2016). We estimated approximately 14,000 deaths to result from the 2010 black carbon (soot) levels, and hundreds of thousands of illness cases, ranging from hospitalizations and emergency department visits to minor respiratory symptoms. Soot Study subjects United States air, ambient Soot Details Death
325. Fang SC, et al. (2012). Normative Aging Study (NAS) In an elderly male population, estimated black carbon exposures were positively associated with markers of systemic inflammation but only in men with coronary heart disease or diabetes. disease Soot Subjects with disease:Coronary Disease | Subjects with disease:Diabetes Mellitus | Study subjects United States serum CXCL8 | IL1B | IL6 | Soot | TNF | VEGFA Details Inflammation | cytokine production involved in inflammatory response | interleukin-1 beta production | interleukin-6 production | interleukin-8 production | regulation of gene expression | tumor necrosis factor production | vascular endothelial growth factor production
326. Arnedo-Pena A, et al. (2003). This accidental contamination led to very high styrene concentrations in water and was related to a high prevalence of subjective symptoms of the eyes, respiratory tract and skin. Styrene Study subjects Spain water, drinking Styrene | Toluene Details Acute Disease | Eye Diseases | Gastrointestinal Diseases | Respiratory Tract Diseases | Skin Diseases
327. Collins JJ, et al. (2009). With the exception of soft tissue sarcoma, the authors found little evidence of increased disease risk from exposure to tetrachlorodibenzodioxin. Tetrachlorodibenzodioxin Workers United States Details Death | Sarcoma
328. Warner M, et al. (2013). Seveso Women's Health Study (SWHS) We found an increased prevalence of metabolic syndrome associated with 2,3,7,8-tetrachlorodibenzo-p-dioxin, but only among women who were the youngest at the time of the explosion. age Tetrachlorodibenzodioxin Study subjects Italy Details Diabetes Mellitus | Metabolic Syndrome | Obesity
329. Tucker JD, et al. (2011). In this population there does not appear to be a strong effect of perchloroethylene exposure on chromosome damage, even for translocations that measure accumulated exposure. However, the dry cleaners did have non-significant increases in translocations, insertions, fragments, dicentrics and junctions compared to laundry workers. Tetrachloroethylene Workers United States air | blood | breath Tetrachloroethylene Details Chromosome Aberrations
330. Carwile JL, et al. (2014). Prenatal tetrachloroethylene exposure was not associated with overall ischemic placental disease, but may increase risk of stillbirth. Tetrachloroethylene Pregnant females United States Tetrachloroethylene Details Placenta Diseases | Prenatal Exposure Delayed Effects | Stillbirth
331. Winnik L, et al. (2004). The aim of this study was the presentation of the chronic tetraethyl lead poisoning of a four-person family. Tetraethyl Lead Children | Subjects with disease:Hallucinations | Study subjects Poland serum Lead Details Lead Poisoning, Nervous System, Adult
332. Xia W, et al. (2016). The results of the present study suggest that prenatal exposure to the current levels of thallium encountered today in China may potentially increase the risk of delivering low birth weight infants. Thallium Study subjects China urine Thallium Details Fetal Growth Retardation
333. Cossellu G, et al. (2016). Susceptibility to Particle Health Effects, miRNAs and Exosomes (SPHERE) Our data suggest that zirconium is more bioactive than titanium and show that miRNAs are relevant molecular mechanisms sensitive to zirconium exposure. Titanium | Zirconium Subjects with disease:Obesity Italy blood | hair MIR142 | MIR152 | MIR193A | MIR323A | MIR335 | MIR494 | MIR99B | Titanium | Zirconium Details
334. Hermann C, et al. (2005). We found that wheeze and recurrent cough in preschool children differ regarding risk factor profile and thus do not appear to have a similar etiology. Tobacco Smoke Pollution Children Denmark Details Cough | Respiratory Sounds
335. Abu-Baker NN, et al. (2010). Women who reported a higher average number of secondhand smoke exposure hours per week from work in the second trimester, home in the third trimester, and outside in the third trimester were at greater risk for having a low birth weight neonate than women who reported a lower average number of secondhand smoke exposure hours. tobacco Tobacco Smoke Pollution Fetuses | Pregnant females Jordan Details Birth Weight | Pregnancy Complications
336. Moore BF, et al. (2016). National Health and Nutrition Examination Survey (NHANES) Interaction results suggest that the prevalence of obesity among children with both high exposure to secondhand smoke and low levels of certain nutrients (dietary fiber, eicosapentaenoic acid, or docosahexaenoic acid) is greater than would be expected due to the effects of the individual exposures alone. age | diet | tobacco Tobacco Smoke Pollution Children United States serum | urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol | Cotinine Details Pediatric Obesity
337. Tran TT, et al. (2015). Thai Cohort Study (TCS) A high proportion of cohort members, especially females, were passive smokers at home and at public transport stations; males were more exposed at workplace and recreational places; we observed a social gradient with more passive smoking in poorer people; we also observed a dose response relationship linking graded smoke exposures to chronic conditions, such as less well-being and more psychological distress. sex | socioeconomic status | tobacco Tobacco Smoke Pollution Study subjects Thailand Details Chronic Disease
338. Comhair SA, et al. (2011). Severe Asthma Research Program (SARP) Environmental tobacco smoke-exposure of asthmatic individuals is associated with worse lung function, higher acuity of exacerbations, more health care utilization, and greater bronchial hyperreactivity. Environmental tobacco smoke-exposure was associated with lower levels of serum SOD activity, particularly in asthmatic women of African heritage. disease | race | sex | tobacco Tobacco Smoke Pollution Subjects with disease:Asthma United States Details Asthma | Disease Progression | superoxide dismutase activity
339. Reese SE, et al. (2017). Norwegian Mother and Child Cohort Study (MoBa) We have developed a novel biomarker in the newborn of exposure to sustained maternal smoking during pregnancy using Illumina450K DNA methylation data. Tobacco Smoke Pollution Infants or newborns | Pregnant females Norway blood, cord | plasma Cotinine Details Birth Weight
340. Zhang Y, et al. (2016). ESTHER Study Our study strongly supports the potential utility of DNA methylation markers as indicators for both current and lifetime smoking exposure and for predicting mortality outcomes, in particular for cardiovascular mortality. Tobacco Smoke Pollution Study subjects Germany Details Cardiovascular Diseases | Death | Neoplasms | DNA methylation
341. Lee KW, et al. (2015). Saguenay Youth Study (SYS) The results of the present study suggest that prenatal exposure to maternal cigarette smoking may interact with OPRM1 to enhance dietary intake of fat, and that the mechanisms of this gene-environment interaction might involve exposure-associated decreases of gene-body DNA methylation in OPRM1. Tobacco Smoke Pollution Children | Subjects with gene influence:OPRM1 Canada Details Obesity | DNA methylation | feeding behavior
342. Lankester J, et al. (2013). National Health and Nutrition Examination Survey (NHANES) Triclosan exposure is associated with increased body mass index; however, stronger effect at moderate than high urinary levels suggests a complex mechanism of action. body mass index Triclosan Study subjects United States urine 2,4-dichlorophenol | Triclosan Details Body Weight
343. Villanueva CM, et al. (2011). Despite the high trihalomethanes levels in some areas and the extensive exposure assessment, results suggest that residential trihalomethanes exposure during pregnancy driven by inhalation and dermal contact routes is not associated with birth weight, small for gestational age, low birth weight, or preterm delivery in Spain. Trihalomethanes Fetuses | Pregnant females Spain water Trihalomethanes Details Birth Weight | Pregnancy Complications | Premature Birth
344. Hwang BF, et al. (2012). The present study is consistent with the hypothesis that the risk of stillbirth is related to prenatal exposure to disinfection by-products. Trihalomethanes Pregnant females Taiwan, Province of China water Trihalomethanes Details Fetal Death
345. Madison RE, et al. (1991). We measured immunologic biomarkers associated with an acute exposure to exothermic byproducts of a ureaformaldehyde spill and found a statistically significant difference for percent and absolute numbers of CD26 T-cells and autoantibodies to formaldehyde-human serum albumin conjugate. urea formaldehyde foam Study subjects United States air, ambient | snow Formaldehyde Details Conjunctivitis | Cough | Diarrhea | Dizziness | Dyspnea | Epistaxis | Exanthema | Fatigue | Headache | Nausea | Pharyngitis | immunoglobulin production involved in immunoglobulin mediated immune response | T cell differentiation
346. Thun MJ, et al. (1982). Families exposed to urea-formaldehyde foam insulation reported no increase in the overall incidence of symptoms, but did report a significant excess of two specific symptoms, 'burning skin' and 'wheezing or difficulty breathing'. urea formaldehyde foam Study subjects United States Details Pain | Respiratory Sounds | Skin Abnormalities
347. Evans KA, et al. (2014). These findings suggest a response to markers of traffic pollution among urban asthmatic children, and effects were strongest among children receiving preventive medications through school, suggesting that this group of children was particularly sensitive to environmental triggers. disease Vehicle Emissions Subjects with disease:Asthma | Children United States air, ambient Carbon Monoxide | Ozone | Particulate Matter | Soot | Sulfur Dioxide Details Disease Progression
348. Venn A, et al. (2005). These findings indicate that living in close proximity to road vehicle traffic is associated with an increased risk of wheeze, but that other environmental factors are also likely to be important. Vehicle Emissions Study subjects Ethiopia Details Respiratory Sounds
349. Zhang X, et al. (2015). Our results show that occupational exposure to diesel engine exhaust can induce increases in micronucleus, nucleoplasmic bridge, and nuclear bud frequencies in peripheral blood lymphocytes. Vehicle Emissions Workers China air, indoor | urine 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 9-phenanthrol | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | Carbon | chrysene | fluoranthene | fluorene | indeno(1,2,3-cd)pyrene | naphthalene | Particulate Matter | phenanthrene | Polycyclic Aromatic Hydrocarbons Details Chromosome Aberrations | Micronuclei, Chromosome-Defective | micronucleus organization
350. Garshick E, et al. (2003). The results of this study suggest that adults are at risk for persistent wheeze and possibly chronic phlegm if they live near a major roadway. Vehicle Emissions Veterans United States Details Respiratory Sounds | Respiratory Tract Diseases
301–350 of 358 results.