Illuminating how chemicals affect human health.
Comparative Toxicogenomics Database

• Basics
• Gene Interactions
• Genes
• Diseases
• Comps
• Pathways
• GO
• References

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

	Disease	Direct Evidence	Enrichment Analysis	Inference Network	Inference Score	References
1.	Metabolic Syndrome X	M				1
2.	Breast Neoplasms			2 genes: AHR | SRC	6.67	3
3.	Pancreatic cancer, adult			1 gene: AHR	6.54	1
4.	Polycystic Kidney, Autosomal Recessive			1 gene: SRC	6.39	1
5.	Hyperoxia			1 gene: AHR	5.99	1
6.	Peanut Hypersensitivity			1 gene: AHR	5.99	1
7.	Silicosis			1 gene: AHR	5.64	1
8.	Ureteral Neoplasms			1 gene: AHR	5.64	1
9.	Chronobiology Disorders			1 gene: AHR	5.34	1
10.	Hyperventilation			1 gene: AHR	5.30	1
11.	Splenic Diseases			1 gene: AHR	4.97	1
12.	Colitis			1 gene: SRC	4.89	1
13.	Bone Resorption			1 gene: AHR	4.82	1
14.	Splenomegaly			1 gene: AHR	4.54	1
15.	Neoplasm Invasiveness			1 gene: SRC	4.52	2
16.	Cardiomegaly			1 gene: SRC	4.41	1
17.	Urinary Bladder Neoplasms			1 gene: SRC	4.37	2
18.	Growth Disorders			1 gene: AHR	4.36	1
19.	Status Epilepticus			1 gene: SRC	4.33	1
20.	Colonic Neoplasms			1 gene: SRC	4.30	1
21.	Atrophy			1 gene: AHR	4.24	2
22.	Dyslipidemias			1 gene: AHR	4.23	1
23.	Heart Defects, Congenital			1 gene: AHR	4.21	1
24.	Infertility, Male			1 gene: AHR	4.21	1
25.	Hypertrophy			1 gene: AHR	4.20	1
26.	Pancreatic Neoplasms			1 gene: AHR	3.96	1
27.	Atherosclerosis			1 gene: AHR	3.90	1
28.	Pneumonia			1 gene: AHR	3.90	1
29.	Arthritis, Rheumatoid			1 gene: AHR	3.87	1
30.	Neoplasms, Experimental			1 gene: AHR	3.84	1
31.	Neoplasm Metastasis			1 gene: AHR	3.72	1
32.	Liver Diseases			1 gene: AHR	3.67	2
33.	Liver Neoplasms			1 gene: AHR	3.61	1
34.	Neoplasms			1 gene: AHR	3.58	1
35.	Tachycardia			1 gene: AHR	3.56	1
36.	Stomach Neoplasms			1 gene: AHR	3.55	1
37.	Peripheral Nervous System Diseases			1 gene: AHR	3.43	1
38.	Inflammation			1 gene: AHR	3.42	1
39.	Hypertension			1 gene: AHR	3.17	1
40.	Drug-Induced Liver Injury			1 gene: AHR	3.13	1