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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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Association type
1–50 of 78 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Cardiomegaly  
4 genes: AHR | CYP1A1 | CYP1B1 | SRC
17.78 3
3. Hyperoxia  
2 genes: AHR | CYP1A1
14.16 2
4. Dermatitis, Contact  
3 genes: AHR | CYP1A1 | CYP1B1
13.54 1
5. Breast Neoplasms  
4 genes: AHR | CYP1A1 | CYP1B1 | SRC
12.97 6
6. Prostatic Neoplasms  
3 genes: AHR | CYP1A1 | CYP1B1
9.50 4
7. Lung Injury  
2 genes: AHR | CYP1A1
8.76 3
8. Infertility, Male  
2 genes: AHR | CYP1A1
8.61 2
9. Neoplasm Invasiveness  
2 genes: AHR | SRC
7.82 3
10. Glaucoma 3, Primary Congenital, A     1 gene: CYP1B1 6.54 1
11. Pancreatic cancer, adult     1 gene: AHR 6.40 1
12. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.10 1
13. Glaucoma 1, Open Angle, A     1 gene: CYP1B1 5.99 1
14. Nystagmus, Congenital     1 gene: AHR 5.85 1
15. Peanut Hypersensitivity     1 gene: AHR 5.85 1
16. Peters anomaly     1 gene: CYP1B1 5.85 1
17. Glaucoma, Primary Open Angle     1 gene: CYP1B1 5.74 1
18. Hypertension  
2 genes: AHR | CYP1A1
5.45 3
19. Silicosis     1 gene: AHR 5.43 1
20. Ureteral Neoplasms     1 gene: AHR 5.43 1
21. Hamartoma     1 gene: CYP1A1 5.32 1
22. Hyperventilation     1 gene: AHR 5.16 1
23. Chronobiology Disorders     1 gene: AHR 5.12 1
24. Urinary Bladder Calculi     1 gene: AHR 4.93 1
25. Splenic Diseases     1 gene: AHR 4.81 1
26. Arteritis     1 gene: CYP1A1 4.72 1
27. Metabolic Diseases     1 gene: AHR 4.69 1
28. Bone Resorption     1 gene: AHR 4.57 1
29. Tobacco Use Disorder     1 gene: AHR 4.57 1
30. Colitis     1 gene: SRC 4.52 1
31. Peripheral Vascular Diseases     1 gene: CYP1A1 4.44 1
32. Mouth Neoplasms     1 gene: CYP1B1 4.33 1
33. Splenomegaly     1 gene: AHR 4.33 1
34. Adenocarcinoma of lung     1 gene: AHR 4.30 1
35. Occupational Diseases     1 gene: CYP1A1 4.23 1
36. Status Epilepticus     1 gene: SRC 4.16 1
37. Arthritis, Experimental     1 gene: AHR 4.15 1
38. Precursor Cell Lymphoblastic Leukemia-Lymphoma     1 gene: CYP1B1 4.15 1
Has associated exposure references.
39. Growth Disorders     1 gene: AHR 4.14 1
40. Hypertrophy, Left Ventricular     1 gene: AHR 4.08 1
41. Urinary Bladder Neoplasms     1 gene: SRC 4.08 2
42. Colonic Neoplasms     1 gene: SRC 4.06 1
43. Dyslipidemias     1 gene: AHR 4.06 1
44. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.05 1
45. Heart Defects, Congenital     1 gene: AHR 4.04 1
46. Adenoma     1 gene: CYP1B1 4.03 1
47. Atrophy     1 gene: AHR 4.03 2
48. Hypertrophy     1 gene: AHR 4.01 1
49. Vascular Diseases     1 gene: AHR 3.97 1
50. Carcinoma, Squamous Cell     1 gene: CYP1B1 3.91 1
1–50 of 78 results.