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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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1–50 of 61 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Hyperoxia  
2 genes: AHR | CYP1A1
14.65 2
3. Cardiomegaly  
3 genes: AHR | CYP1A1 | SRC
13.48 3
4. Breast Neoplasms  
3 genes: AHR | CYP1A1 | SRC
10.00 4
5. Infertility, Male  
2 genes: AHR | CYP1A1
9.10 2
6. Pancreatic cancer, adult     1 gene: AHR 6.55 1
7. Prostatic Neoplasms  
2 genes: AHR | CYP1A1
6.43 3
8. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.24 1
9. Nystagmus, Congenital     1 gene: AHR 6.21 1
10. Peanut Hypersensitivity     1 gene: AHR 6.00 1
11. Hypertension  
2 genes: AHR | CYP1A1
5.94 3
12. Silicosis     1 gene: AHR 5.58 1
13. Ureteral Neoplasms     1 gene: AHR 5.58 1
14. Hamartoma     1 gene: CYP1A1 5.47 1
15. Hyperventilation     1 gene: AHR 5.31 1
16. Chronobiology Disorders     1 gene: AHR 5.27 1
17. Urinary Bladder Calculi     1 gene: AHR 5.08 1
18. Splenic Diseases     1 gene: AHR 4.96 1
19. Arteritis     1 gene: CYP1A1 4.86 1
20. Bone Resorption     1 gene: AHR 4.76 1
21. Colitis     1 gene: SRC 4.72 1
22. Tobacco Use Disorder     1 gene: AHR 4.72 1
23. Peripheral Vascular Diseases     1 gene: CYP1A1 4.59 1
24. Splenomegaly     1 gene: AHR 4.51 1
25. Adenocarcinoma of lung     1 gene: AHR 4.47 1
26. Occupational Diseases     1 gene: CYP1A1 4.39 1
27. Neoplasm Invasiveness     1 gene: SRC 4.32 2
28. Arthritis, Experimental     1 gene: AHR 4.31 1
29. Status Epilepticus     1 gene: SRC 4.30 1
30. Growth Disorders     1 gene: AHR 4.29 1
31. Urinary Bladder Neoplasms     1 gene: SRC 4.26 2
32. Hypertrophy, Left Ventricular     1 gene: AHR 4.23 1
33. Dyslipidemias     1 gene: AHR 4.22 1
34. Colonic Neoplasms     1 gene: SRC 4.20 1
35. Heart Defects, Congenital     1 gene: AHR 4.20 1
36. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.19 1
37. Atrophy     1 gene: AHR 4.18 2
38. Hypertrophy     1 gene: AHR 4.17 1
39. Vascular Diseases     1 gene: AHR 4.12 1
40. Lung Injury     1 gene: CYP1A1 3.99 1
41. Pancreatic Neoplasms     1 gene: AHR 3.94 1
42. Kidney Neoplasms     1 gene: CYP1A1 3.93 1
43. Pneumonia     1 gene: AHR 3.88 1
44. Arthritis, Rheumatoid     1 gene: AHR 3.86 1
45. Atherosclerosis     1 gene: AHR 3.86 1
46. Abortion, Spontaneous     1 gene: CYP1A1 3.83 1
47. Hypersensitivity     1 gene: CYP1A1 3.79 1
48. Neoplasms, Experimental     1 gene: AHR 3.77 1
49. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.68 1
50. Liver Diseases     1 gene: AHR 3.67 2
1–50 of 61 results.