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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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1–50 of 57 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Breast Neoplasms  
3 genes: AHR | CYP1A1 | SRC
9.99 4
3. Infertility, Male  
2 genes: AHR | CYP1A1
9.09 2
4. Cardiomegaly  
2 genes: CYP1A1 | SRC
8.35 2
5. Pancreatic cancer, adult     1 gene: AHR 6.52 1
6. Prostatic Neoplasms  
2 genes: AHR | CYP1A1
6.44 3
7. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.24 1
8. Nystagmus, Congenital     1 gene: AHR 6.18 1
9. Peanut Hypersensitivity     1 gene: AHR 5.98 1
10. Hypertension  
2 genes: AHR | CYP1A1
5.87 3
11. Hyperoxia     1 gene: AHR 5.83 1
12. Silicosis     1 gene: AHR 5.55 1
13. Ureteral Neoplasms     1 gene: AHR 5.55 1
14. Hamartoma     1 gene: CYP1A1 5.43 1
15. Chronobiology Disorders     1 gene: AHR 5.33 1
16. Hyperventilation     1 gene: AHR 5.28 1
17. Urinary Bladder Calculi     1 gene: AHR 5.05 1
18. Splenic Diseases     1 gene: AHR 4.94 1
19. Arteritis     1 gene: CYP1A1 4.83 1
20. Colitis     1 gene: SRC 4.77 1
21. Bone Resorption     1 gene: AHR 4.75 1
22. Peripheral Vascular Diseases     1 gene: CYP1A1 4.55 1
23. Adenocarcinoma of lung     1 gene: AHR 4.49 1
24. Splenomegaly     1 gene: AHR 4.48 1
25. Neoplasm Invasiveness     1 gene: SRC 4.38 2
26. Occupational Diseases     1 gene: CYP1A1 4.37 1
27. Growth Disorders     1 gene: AHR 4.31 1
28. Status Epilepticus     1 gene: SRC 4.30 1
29. Urinary Bladder Neoplasms     1 gene: SRC 4.27 2
30. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.25 1
31. Colonic Neoplasms     1 gene: SRC 4.24 1
32. Dyslipidemias     1 gene: AHR 4.21 1
33. Hypertrophy, Left Ventricular     1 gene: AHR 4.21 1
34. Heart Defects, Congenital     1 gene: AHR 4.19 1
35. Atrophy     1 gene: AHR 4.17 2
36. Hypertrophy     1 gene: AHR 4.16 1
37. Pancreatic Neoplasms     1 gene: AHR 3.93 1
38. Kidney Neoplasms     1 gene: CYP1A1 3.92 1
39. Atherosclerosis     1 gene: AHR 3.87 1
40. Pneumonia     1 gene: AHR 3.87 1
41. Arthritis, Rheumatoid     1 gene: AHR 3.84 1
42. Abortion, Spontaneous     1 gene: CYP1A1 3.80 1
43. Hypersensitivity     1 gene: CYP1A1 3.80 1
44. Neoplasms, Experimental     1 gene: AHR 3.75 1
45. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.65 1
46. Diabetes Mellitus, Experimental     1 gene: CYP1A1 3.65 1
47. Neoplasm Metastasis     1 gene: AHR 3.65 1
48. Liver Diseases     1 gene: AHR 3.64 2
49. Drug Eruptions     1 gene: CYP1A1 3.58 1
50. Liver Neoplasms     1 gene: AHR 3.57 1
1–50 of 57 results.