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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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Disease category
Association type
1–50 of 77 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Cardiomegaly  
4 genes: AHR | CYP1A1 | CYP1B1 | SRC
17.87 3
3. Hyperoxia  
2 genes: AHR | CYP1A1
14.22 2
4. Dermatitis, Contact  
3 genes: AHR | CYP1A1 | CYP1B1
13.64 1
5. Breast Neoplasms  
4 genes: AHR | CYP1A1 | CYP1B1 | SRC
12.95 6
6. Prostatic Neoplasms  
3 genes: AHR | CYP1A1 | CYP1B1
9.48 4
7. Lung Injury  
2 genes: AHR | CYP1A1
8.71 3
8. Infertility, Male  
2 genes: AHR | CYP1A1
8.60 2
9. Abortion, Spontaneous  
2 genes: AHR | CYP1A1
8.38 2
10. Neoplasm Invasiveness  
2 genes: AHR | SRC
7.59 3
11. Glaucoma 3, Primary Congenital, A     1 gene: CYP1B1 6.55 1
12. Pancreatic cancer, adult     1 gene: AHR 6.42 1
13. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.11 1
14. Glaucoma 1, Open Angle, A     1 gene: CYP1B1 6.00 1
15. Nystagmus, Congenital     1 gene: AHR 5.87 1
16. Peters anomaly     1 gene: CYP1B1 5.86 1
17. Peanut Hypersensitivity     1 gene: AHR 5.72 1
18. Glaucoma, Primary Open Angle     1 gene: CYP1B1 5.51 1
19. Hypertension  
2 genes: AHR | CYP1A1
5.49 3
20. Ureteral Neoplasms     1 gene: AHR 5.44 1
21. Hamartoma     1 gene: CYP1A1 5.35 1
22. Silicosis     1 gene: AHR 5.27 1
23. Hyperventilation     1 gene: AHR 5.17 1
24. Chronobiology Disorders     1 gene: AHR 5.13 1
25. Urinary Bladder Calculi     1 gene: AHR 4.94 1
26. Splenic Diseases     1 gene: AHR 4.77 1
27. Arteritis     1 gene: CYP1A1 4.75 1
28. Metabolic Diseases     1 gene: AHR 4.70 1
29. Tobacco Use Disorder     1 gene: AHR 4.56 1
30. Bone Resorption     1 gene: AHR 4.55 1
31. Colitis     1 gene: SRC 4.51 1
32. Peripheral Vascular Diseases     1 gene: CYP1A1 4.47 1
33. Mouth Neoplasms     1 gene: CYP1B1 4.31 1
34. Splenomegaly     1 gene: AHR 4.30 1
35. Adenocarcinoma of lung     1 gene: AHR 4.25 1
36. Occupational Diseases     1 gene: CYP1A1 4.25 1
37. Status Epilepticus     1 gene: SRC 4.16 1
38. Growth Disorders     1 gene: AHR 4.13 1
39. Precursor Cell Lymphoblastic Leukemia-Lymphoma     1 gene: CYP1B1 4.11 1
Has associated exposure references.
40. Arthritis, Experimental     1 gene: AHR 4.09 1
41. Hypertrophy, Left Ventricular     1 gene: AHR 4.09 1
42. Urinary Bladder Neoplasms     1 gene: SRC 4.08 2
43. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.06 1
44. Colonic Neoplasms     1 gene: SRC 4.04 1
45. Dyslipidemias     1 gene: AHR 4.04 1
46. Adenoma     1 gene: CYP1B1 4.03 1
47. Atrophy     1 gene: AHR 4.03 2
48. Heart Defects, Congenital     1 gene: AHR 4.03 1
49. Hypertrophy     1 gene: AHR 3.99 1
50. Vascular Diseases     1 gene: AHR 3.98 1
1–50 of 77 results.