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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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1–50 of 58 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Hyperoxia  
2 genes: AHR | CYP1A1
14.59 2
3. Cardiomegaly  
3 genes: AHR | CYP1A1 | SRC
13.47 3
4. Breast Neoplasms  
3 genes: AHR | CYP1A1 | SRC
9.96 4
5. Infertility, Male  
2 genes: AHR | CYP1A1
9.11 2
6. Pancreatic cancer, adult     1 gene: AHR 6.53 1
7. Prostatic Neoplasms  
2 genes: AHR | CYP1A1
6.42 3
8. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.24 1
9. Nystagmus, Congenital     1 gene: AHR 6.19 1
10. Peanut Hypersensitivity     1 gene: AHR 5.98 1
11. Hypertension  
2 genes: AHR | CYP1A1
5.89 3
12. Silicosis     1 gene: AHR 5.56 1
13. Ureteral Neoplasms     1 gene: AHR 5.56 1
14. Hamartoma     1 gene: CYP1A1 5.44 1
15. Hyperventilation     1 gene: AHR 5.29 1
16. Chronobiology Disorders     1 gene: AHR 5.25 1
17. Urinary Bladder Calculi     1 gene: AHR 5.06 1
18. Splenic Diseases     1 gene: AHR 4.95 1
19. Arteritis     1 gene: CYP1A1 4.84 1
20. Colitis     1 gene: SRC 4.76 1
21. Bone Resorption     1 gene: AHR 4.74 1
22. Peripheral Vascular Diseases     1 gene: CYP1A1 4.56 1
23. Splenomegaly     1 gene: AHR 4.49 1
24. Adenocarcinoma of lung     1 gene: AHR 4.45 1
25. Occupational Diseases     1 gene: CYP1A1 4.38 1
26. Neoplasm Invasiveness     1 gene: SRC 4.36 2
27. Status Epilepticus     1 gene: SRC 4.30 1
28. Growth Disorders     1 gene: AHR 4.28 1
29. Urinary Bladder Neoplasms     1 gene: SRC 4.26 2
30. Colonic Neoplasms     1 gene: SRC 4.24 1
31. Dyslipidemias     1 gene: AHR 4.21 1
32. Hypertrophy, Left Ventricular     1 gene: AHR 4.21 1
33. Heart Defects, Congenital     1 gene: AHR 4.20 1
34. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.20 1
35. Atrophy     1 gene: AHR 4.16 2
36. Hypertrophy     1 gene: AHR 4.16 1
37. Lung Injury     1 gene: CYP1A1 4.00 1
38. Kidney Neoplasms     1 gene: CYP1A1 3.93 1
39. Pancreatic Neoplasms     1 gene: AHR 3.93 1
40. Pneumonia     1 gene: AHR 3.88 1
41. Atherosclerosis     1 gene: AHR 3.87 1
42. Arthritis, Rheumatoid     1 gene: AHR 3.85 1
43. Abortion, Spontaneous     1 gene: CYP1A1 3.81 1
44. Hypersensitivity     1 gene: CYP1A1 3.77 1
45. Neoplasms, Experimental     1 gene: AHR 3.75 1
46. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.66 1
47. Diabetes Mellitus, Experimental     1 gene: CYP1A1 3.65 1
48. Liver Diseases     1 gene: AHR 3.65 2
49. Neoplasm Metastasis     1 gene: AHR 3.65 1
50. Drug Eruptions     1 gene: CYP1A1 3.59 1
1–50 of 58 results.