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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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1–50 of 59 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Hyperoxia  
2 genes: AHR | CYP1A1
14.59 2
3. Cardiomegaly  
3 genes: AHR | CYP1A1 | SRC
13.42 3
4. Breast Neoplasms  
3 genes: AHR | CYP1A1 | SRC
9.96 4
5. Infertility, Male  
2 genes: AHR | CYP1A1
9.09 2
6. Pancreatic cancer, adult     1 gene: AHR 6.53 1
7. Prostatic Neoplasms  
2 genes: AHR | CYP1A1
6.43 3
8. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.24 1
9. Nystagmus, Congenital     1 gene: AHR 6.19 1
10. Peanut Hypersensitivity     1 gene: AHR 5.98 1
11. Hypertension  
2 genes: AHR | CYP1A1
5.89 3
12. Silicosis     1 gene: AHR 5.56 1
13. Ureteral Neoplasms     1 gene: AHR 5.56 1
14. Hamartoma     1 gene: CYP1A1 5.44 1
15. Hyperventilation     1 gene: AHR 5.29 1
16. Chronobiology Disorders     1 gene: AHR 5.25 1
17. Urinary Bladder Calculi     1 gene: AHR 5.06 1
18. Splenic Diseases     1 gene: AHR 4.94 1
19. Arteritis     1 gene: CYP1A1 4.84 1
20. Colitis     1 gene: SRC 4.76 1
21. Bone Resorption     1 gene: AHR 4.74 1
22. Peripheral Vascular Diseases     1 gene: CYP1A1 4.56 1
23. Splenomegaly     1 gene: AHR 4.49 1
24. Adenocarcinoma of lung     1 gene: AHR 4.45 1
25. Occupational Diseases     1 gene: CYP1A1 4.36 1
26. Neoplasm Invasiveness     1 gene: SRC 4.35 2
27. Arthritis, Experimental     1 gene: AHR 4.31 1
28. Status Epilepticus     1 gene: SRC 4.30 1
29. Growth Disorders     1 gene: AHR 4.28 1
30. Urinary Bladder Neoplasms     1 gene: SRC 4.26 2
31. Colonic Neoplasms     1 gene: SRC 4.23 1
32. Hypertrophy, Left Ventricular     1 gene: AHR 4.21 1
33. Dyslipidemias     1 gene: AHR 4.20 1
34. Heart Defects, Congenital     1 gene: AHR 4.20 1
35. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.20 1
36. Atrophy     1 gene: AHR 4.16 2
37. Hypertrophy     1 gene: AHR 4.16 1
38. Lung Injury     1 gene: CYP1A1 4.00 1
39. Kidney Neoplasms     1 gene: CYP1A1 3.93 1
40. Pancreatic Neoplasms     1 gene: AHR 3.93 1
41. Pneumonia     1 gene: AHR 3.87 1
42. Atherosclerosis     1 gene: AHR 3.86 1
43. Arthritis, Rheumatoid     1 gene: AHR 3.85 1
44. Abortion, Spontaneous     1 gene: CYP1A1 3.80 1
45. Hypersensitivity     1 gene: CYP1A1 3.77 1
46. Neoplasms, Experimental     1 gene: AHR 3.75 1
47. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.66 1
48. Diabetes Mellitus, Experimental     1 gene: CYP1A1 3.65 1
49. Liver Diseases     1 gene: AHR 3.65 2
50. Neoplasm Metastasis     1 gene: AHR 3.64 1
1–50 of 59 results.