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Chemical 1,2,3,4,6,7,8-heptachlorodibenzodioxin

These diseases are associated with 1,2,3,4,6,7,8-heptachlorodibenzodioxin. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Disease categories [Show chart]

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1–50 of 59 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Metabolic Syndrome X M     1
2. Hyperoxia  
2 genes: AHR | CYP1A1
14.64 2
3. Cardiomegaly  
3 genes: AHR | CYP1A1 | SRC
13.51 3
4. Breast Neoplasms  
3 genes: AHR | CYP1A1 | SRC
10.01 4
5. Infertility, Male  
2 genes: AHR | CYP1A1
9.09 2
6. Pancreatic cancer, adult     1 gene: AHR 6.55 1
7. Prostatic Neoplasms  
2 genes: AHR | CYP1A1
6.43 3
8. Polycystic Kidney, Autosomal Recessive     1 gene: SRC 6.25 1
9. Nystagmus, Congenital     1 gene: AHR 6.21 1
10. Peanut Hypersensitivity     1 gene: AHR 6.00 1
11. Hypertension  
2 genes: AHR | CYP1A1
5.94 3
12. Silicosis     1 gene: AHR 5.58 1
13. Ureteral Neoplasms     1 gene: AHR 5.58 1
14. Hamartoma     1 gene: CYP1A1 5.46 1
15. Hyperventilation     1 gene: AHR 5.31 1
16. Chronobiology Disorders     1 gene: AHR 5.27 1
17. Urinary Bladder Calculi     1 gene: AHR 5.08 1
18. Splenic Diseases     1 gene: AHR 4.97 1
19. Arteritis     1 gene: CYP1A1 4.86 1
20. Bone Resorption     1 gene: AHR 4.76 1
21. Colitis     1 gene: SRC 4.74 1
22. Peripheral Vascular Diseases     1 gene: CYP1A1 4.58 1
23. Splenomegaly     1 gene: AHR 4.51 1
24. Adenocarcinoma of lung     1 gene: AHR 4.47 1
25. Occupational Diseases     1 gene: CYP1A1 4.39 1
26. Arthritis, Experimental     1 gene: AHR 4.34 1
27. Neoplasm Invasiveness     1 gene: SRC 4.34 2
28. Status Epilepticus     1 gene: SRC 4.31 1
29. Growth Disorders     1 gene: AHR 4.30 1
30. Urinary Bladder Neoplasms     1 gene: SRC 4.27 2
31. Dyslipidemias     1 gene: AHR 4.23 1
32. Hypertrophy, Left Ventricular     1 gene: AHR 4.23 1
33. Heart Defects, Congenital     1 gene: AHR 4.22 1
34. Pulmonary Disease, Chronic Obstructive     1 gene: CYP1A1 4.22 1
35. Colonic Neoplasms     1 gene: SRC 4.21 1
36. Atrophy     1 gene: AHR 4.18 2
37. Hypertrophy     1 gene: AHR 4.18 1
38. Lung Injury     1 gene: CYP1A1 4.01 1
39. Pancreatic Neoplasms     1 gene: AHR 3.94 1
40. Kidney Neoplasms     1 gene: CYP1A1 3.93 1
41. Pneumonia     1 gene: AHR 3.89 1
42. Arthritis, Rheumatoid     1 gene: AHR 3.87 1
43. Atherosclerosis     1 gene: AHR 3.87 1
44. Abortion, Spontaneous     1 gene: CYP1A1 3.83 1
45. Hypersensitivity     1 gene: CYP1A1 3.79 1
46. Neoplasms, Experimental     1 gene: AHR 3.77 1
47. Dermatitis, Allergic Contact     1 gene: CYP1A1 3.68 1
48. Liver Diseases     1 gene: AHR 3.67 2
49. Diabetes Mellitus, Experimental     1 gene: CYP1A1 3.66 1
50. Neoplasm Metastasis     1 gene: AHR 3.66 1
1–50 of 59 results.