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Chemical 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide

1–34 of 34 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide apoptotic process Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased apoptotic process] 1: Rattus norvegicus Hepatocytes | Cells, Cultured
38 genes: AHR | AKT1 | ATG5 | BAD | BIRC5 | CD14 | CGB3 | CHEK1 | DDIT3 | DDIT4 | DIABLO | GADD45A | GREM1 | HIPK2 | IFNG | IL17A | IL1B | IRAK3 | IRF1 | ITPR1 | KLF11 | MAPK1 | MAPK3 | NLRP2 | PAK4 | PCSK9 | PHLDA2 | PTPN6 | RPS6KA3 | RTKN | SP110 | SRA1 | TCIM | TNF | TNFSF14 | TP53 | TRIB3 | ZC3H12A
1
2. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of cell proliferation Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin affects negative regulation of cell proliferation] 1: Mus musculus Liver | Stem Cells | Cells, Cultured
32 genes: AXIN2 | BTG2 | BTG3 | CDKN1A | CDKN1B | CDKN3 | COL18A1 | CTNNB1 | CXCL8 | CYP1B1 | EREG | ETS1 | FGF2 | FOSL1 | H19 | HSPA1A | IFNG | IL1B | IL6 | IRF1 | KLF11 | NOTCH1 | PPARG | PTGS2 | PTPN6 | SKAP2 | SOX9 | TGIF1 | TNF | TP53 | TP53I11 | ZNF503
1
3. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of heart looping Flame Retardants 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Flame Retardants results in increased negative regulation of heart looping] 1: Danio rerio Embryo, Nonmammalian | Heart   1
4. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of heart looping Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of heart looping] 1: Danio rerio Embryo, Nonmammalian | Heart   1
5. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide regulation of heart rate Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin affects regulation of heart rate] 1: Danio rerio Embryo, Nonmammalian | Heart
2 genes: CALM2 | IRX5
1
6. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of transport ABCG2 | Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ABCG2 protein affects positive regulation of transport]] 1: Capra hircus Madin Darby Canine Kidney Cells   1
7. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of transport ABCG2 | prochloraz 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [prochloraz promotes the reaction [ABCG2 protein affects positive regulation of transport]] 1: Capra hircus Madin Darby Canine Kidney Cells   1
8. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide apoptotic process Smoke 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [Smoke analog results in increased apoptotic process] 1: Mus musculus Lung | Fibroblasts | Cells, Cultured
38 genes: AHR | AKT1 | ATG5 | BAD | BIRC5 | CD14 | CGB3 | CHEK1 | DDIT3 | DDIT4 | DIABLO | GADD45A | GREM1 | HIPK2 | IFNG | IL17A | IL1B | IRAK3 | IRF1 | ITPR1 | KLF11 | MAPK1 | MAPK3 | NLRP2 | PAK4 | PCSK9 | PHLDA2 | PTPN6 | RPS6KA3 | RTKN | SP110 | SRA1 | TCIM | TNF | TNFSF14 | TP53 | TRIB3 | ZC3H12A
1
9. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide interleukin-17 secretion AHR [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide binds to and results in decreased activity of AHR protein] which results in decreased interleukin-17 secretion 1: Mus musculus Th17 Cells   1
10. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide interleukin-22 secretion AHR [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide binds to and results in decreased activity of AHR protein] which results in decreased interleukin-22 secretion 1: Mus musculus Th17 Cells   1
11. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide fat cell differentiation 3,4,5,3',4'-pentachlorobiphenyl 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased fat cell differentiation] 1: Homo sapiens Stem Cells | Cell Line
9 genes: BBS7 | CCND1 | IL11 | INSR | MED1 | NR4A2 | PPARG | TMEM120B | VIM
1
12. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide fat cell differentiation 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in increased fat cell differentiation 1: Homo sapiens Stem Cells | Cell Line
9 genes: BBS7 | CCND1 | IL11 | INSR | MED1 | NR4A2 | PPARG | TMEM120B | VIM
1
13. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of reactive oxygen species biosynthetic process 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Homo sapiens Breast | Cell Line, Tumor   1
14. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of JNK cascade 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased positive regulation of JNK cascade] 1: Homo sapiens Breast | Cell Line, Tumor
6 genes: CTGF | GADD45A | HIPK2 | IL1B | RDX | TNF
1
15. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of p38MAPK cascade 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased positive regulation of p38MAPK cascade] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: GADD45A | IL1B | ZC3H12A
1
16. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide nitric oxide biosynthetic process Benzo(a)pyrene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene affects nitric oxide biosynthetic process] 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line
4 genes: AKT1 | CYP1B1 | HSP90AA1 | NOS2
1
17. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide regulation of mitochondrial membrane potential Benzo(a)pyrene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene affects regulation of mitochondrial membrane potential] 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line 1 gene: NDUFS1 1
18. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of cardiac muscle cell differentiation 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in increased negative regulation of cardiac muscle cell differentiation 1: Mus musculus Mouse Embryonic Stem Cells | Myocytes, Cardiac 1 gene: DKK1 1
19. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide regulation of cardiac muscle cell contraction 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects regulation of cardiac muscle cell contraction 1: Mus musculus Mouse Embryonic Stem Cells | Myocytes, Cardiac   1
20. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cell proliferation 1,12-benzoperylene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in decreased cell proliferation] 1: Homo sapiens Bronchi | Cell Line
31 genes: ACHE | AKT1 | ANXA7 | AREG | AURKB | AXIN2 | BAD | CD74 | CTNNB1 | CYP1A1 | CYR61 | DDIT4 | DTYMK | EREG | FGF2 | INSIG1 | ITGA2 | NUPR1 | PAK4 | PCNA | PRDX1 | PRKAR1B | PRKDC | PTPN6 | RAP1B | RAPGEF3 | SRA1 | SRC | TNF | TP53 | USP8
1
21. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide detection of oxidative stress 1,12-benzoperylene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [1,12-benzoperylene results in increased detection of oxidative stress] 1: Homo sapiens Bronchi | Cell Line 1 gene: ADIPOQ 1
22. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cell migration 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased cell migration 1: Homo sapiens Fetus | Lung | Fibroblasts | Cell Line
5 genes: CTGF | HBEGF | MDK | PAK4 | SRC
1
23. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cell migration Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased cell migration] 1: Homo sapiens Fetus | Lung | Fibroblasts | Cell Line
5 genes: CTGF | HBEGF | MDK | PAK4 | SRC
1
24. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cellular calcium ion homeostasis Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin affects cellular calcium ion homeostasis] 1: Homo sapiens Fetus | Lung | Fibroblasts | Cell Line
5 genes: ANXA7 | ATF4 | PGM1 | STC2 | XK
1
25. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of immunoglobulin production AHR | Lipopolysaccharides AHR gene mutant form inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [Lipopolysaccharides results in increased positive regulation of immunoglobulin production]] 1: Rattus norvegicus Spleen | B-Lymphocytes 1 gene: IL4R 1
26. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of cell proliferation AHR | Lipopolysaccharides AHR gene mutant form inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [Lipopolysaccharides results in increased positive regulation of cell proliferation]] 1: Rattus norvegicus Spleen | B-Lymphocytes
44 genes: AKT1 | ALDH3A1 | AREG | ATF3 | BIRC5 | CCND1 | CDKN1B | COL18A1 | CSF2 | CTGF | CTNNB1 | CXCL10 | CXCL5 | EREG | ETS1 | FGF2 | FOSL1 | GADD45GIP1 | GAREM1 | GREM1 | HBEGF | HILPDA | HIPK2 | HSP90AA1 | ID3 | IFNG | IL11 | IL1B | IL6 | INSR | MAPK1 | MED1 | MLXIPL | NOTCH1 | PDGFA | PTGS2 | PTPN6 | RUNX2 | SOX9 | SSR1 | TNC | TNF | TSLP | VIPR1
1
27. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of immunoglobulin production Lipopolysaccharides 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [Lipopolysaccharides results in increased positive regulation of immunoglobulin production] 1: Rattus norvegicus Spleen | B-Lymphocytes 1 gene: IL4R 1
28. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide positive regulation of cell proliferation Lipopolysaccharides 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [Lipopolysaccharides results in increased positive regulation of cell proliferation] 1: Rattus norvegicus Spleen | B-Lymphocytes
44 genes: AKT1 | ALDH3A1 | AREG | ATF3 | BIRC5 | CCND1 | CDKN1B | COL18A1 | CSF2 | CTGF | CTNNB1 | CXCL10 | CXCL5 | EREG | ETS1 | FGF2 | FOSL1 | GADD45GIP1 | GAREM1 | GREM1 | HBEGF | HILPDA | HIPK2 | HSP90AA1 | ID3 | IFNG | IL11 | IL1B | IL6 | INSR | MAPK1 | MED1 | MLXIPL | NOTCH1 | PDGFA | PTGS2 | PTPN6 | RUNX2 | SOX9 | SSR1 | TNC | TNF | TSLP | VIPR1
1
29. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of immunoglobulin secretion Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of immunoglobulin secretion] 1: Homo sapiens B-Lymphocytes   1
30. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide negative regulation of humoral immune response mediated by circulating immunoglobulin Tetrachlorodibenzodioxin 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of humoral immune response mediated by circulating immunoglobulin] 1: Homo sapiens B-Lymphocytes
2 genes: FOXJ1 | PTPN6
1
31. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide DNA damage response, detection of DNA damage Benzo(a)pyrene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Lung | Cell Line, Transformed 1 gene: PCNA 1
32. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide DNA damage response, detection of DNA damage benzo(a)pyrene 7,8-diol-9,10-epoxide-N2-deoxyguanosine | Benzo(a)pyrene 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Benzo(a)pyrene results in increased abundance of benzo(a)pyrene 7,8-diol-9,10-epoxide-N2-deoxyguanosine] which results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Lung | Cell Line, Transformed 1 gene: PCNA 1
33. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cellular response to inorganic substance 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased cellular response to inorganic substance 1: Homo sapiens Bronchi | Epithelial Cells | Cell Line   1
34. 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide cellular response to inorganic substance Particulate Matter [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased cellular response to inorganic substance] which results in decreased susceptibility to Particulate Matter 1: Homo sapiens Bronchi | Epithelial Cells | Cell Line   1
1–34 of 34 results.