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Chemical Alarmins

Name Alarmins
Equivalent Terms Alarmin | Alarmin Proteins | Damage Associated Molecular Pattern Molecules | Damage-Associated Molecular Pattern Molecules | Danger Associated Molecular Pattern Molecules | Danger-Associated Molecular Pattern Molecules
Definition A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D000067531
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ChemicalsBiological Factors Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Alarmins

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