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Chemical Dioxins and Dioxin-like Compounds

1–50 of 1,257 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1,2,3,4,6,7,8-heptachlorodibenzodioxin regulation of blood pressure 1,2,3,4,6,7,8-heptachlorodibenzodioxin affects regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: AHR 1
2. 2,2',3,3',4,4',5-heptachlorobiphenyl interleukin-8 production 2,2',3,3',4,4',5-heptachlorobiphenyl affects interleukin-8 production 1: Homo sapiens     1
3. 2,2',3,3',4,4',5-heptachlorobiphenyl production of molecular mediator of immune response 2,2',3,3',4,4',5-heptachlorobiphenyl results in increased production of molecular mediator of immune response 1: Homo sapiens Blood   1
4. 2,2',3,3',4,4',5-heptachlorobiphenyl cognition 2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased cognition 1: Homo sapiens Brain   1
5. 2,2',3,3',4,4',5-heptachlorobiphenyl triglyceride metabolic process 2,2',3,3',4,4',5-heptachlorobiphenyl affects triglyceride metabolic process 1: Homo sapiens Serum   1
6. 2,2',3,3',4,4',5-heptachlorobiphenyl neural crest cell migration 2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased neural crest cell migration 1: Homo sapiens Neural Stem Cells | Cell Line   1
7. 2,2',3,3',4,4',5-heptachlorobiphenyl negative regulation of androgen receptor activity 2,2',3,3',4,4',5-heptachlorobiphenyl results in increased negative regulation of androgen receptor activity 1: Homo sapiens Osteoblasts | Cell Line, Tumor   1
8. 2,2',3,3',4,4',5-heptachlorobiphenyl negative regulation of androgen receptor activity Dihydrotestosterone [2,2',3,3',4,4',5-heptachlorobiphenyl results in increased negative regulation of androgen receptor activity] which results in decreased susceptibility to Dihydrotestosterone 1: Homo sapiens Osteoblasts | Cell Line, Tumor   1
9. 2,2',3,3',4,4',5-heptachlorobiphenyl progesterone receptor signaling pathway 2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased progesterone receptor signaling pathway 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
10. 2,2',3,3',4,4',5-heptachlorobiphenyl progesterone receptor signaling pathway 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione [2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
11. 2,2',3',4,4',5-hexachlorobiphenyl production of molecular mediator of immune response 2,2',3',4,4',5-hexachlorobiphenyl results in increased production of molecular mediator of immune response 1: Homo sapiens Blood   1
12. 2,2',3',4,4',5-hexachlorobiphenyl flagellated sperm motility 2,2',3',4,4',5-hexachlorobiphenyl results in decreased flagellated sperm motility 1: Homo sapiens Spermatozoa
8 genes: ATP2B4 | CATSPERD | CHRNA7 | GAPDHS | MET | NEURL1A | TEKT2 | TTLL5
1
13. 2,2',3',4,4',5-hexachlorobiphenyl hormone metabolic process 2,2',3',4,4',5-hexachlorobiphenyl affects hormone metabolic process 1: Homo sapiens Blood   1
14. 2,2',3',4,4',5-hexachlorobiphenyl cognition 2,2',3',4,4',5-hexachlorobiphenyl results in decreased cognition 1: Homo sapiens Brain
10 genes: APP | CHRM1 | CHRNA7 | CTNS | FAM107A | GNAS | GRM5 | HRH3 | HTR4 | TNF
1
15. 2,2',3',4,4',5-hexachlorobiphenyl regulation of thyroid-stimulating hormone secretion 2,2',3',4,4',5-hexachlorobiphenyl affects regulation of thyroid-stimulating hormone secretion 1: Homo sapiens Serum   1
16. 2,2',3',4,4',5-hexachlorobiphenyl thyroid hormone metabolic process 2,2',3',4,4',5-hexachlorobiphenyl affects thyroid hormone metabolic process 1: Homo sapiens Serum
2 genes: SLCO4A1 | TTR
1
17. 2,2',3',4,4',5-hexachlorobiphenyl interleukin-4 production 2,2',3',4,4',5-hexachlorobiphenyl results in decreased interleukin-4 production 1: Homo sapiens Plasma   1
18. 2,2',3',4,4',5-hexachlorobiphenyl hypermethylation of CpG island 2,2',3',4,4',5-hexachlorobiphenyl affects hypermethylation of CpG island 1: Homo sapiens Leukocytes 1 gene: UHRF1 1
19. 2,2',3',4,4',5-hexachlorobiphenyl long-term memory 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | APP | PCB 180 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180 co-treated with APP protein modified form] results in decreased long-term memory 1: Mus musculus  
11 genes: CALB1 | CAMK4 | CCND2 | CTNS | GCLM | GRIN1 | GRIN2B | SHANK1 | SLC17A7 | SNAP25 | TAC1
1
20. 2,2',3',4,4',5-hexachlorobiphenyl regulation of cell size 2,2',3',4,4',5-hexachlorobiphenyl affects regulation of cell size 1: Mus musculus Epididymis | Adipose Tissue, White | Adipocytes
5 genes: ATP2B2 | EZR | IQGAP3 | KEL | XK
1
21. 2,2',3',4,4',5-hexachlorobiphenyl regulation of cell size 2,2',3',4,4',5-hexachlorobiphenyl affects regulation of cell size 1: Mus musculus 3T3-L1 Cells
5 genes: ATP2B2 | EZR | IQGAP3 | KEL | XK
1
22. 2,2',3',4,4',5-hexachlorobiphenyl cell growth TNF 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [TNF protein results in decreased cell growth] 1: Mus musculus 3T3-L1 Cells   1
23. 2,2',3',4,4',5-hexachlorobiphenyl apoptotic process TNF 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [TNF protein results in increased apoptotic process] 1: Mus musculus 3T3-L1 Cells
94 genes: ACIN1 | AHR | AKT2 | AKTIP | ALDOC | APP | ATM | ATP5F1A | BABAM2 | BCL2L1 | BCL2L14 | BIRC3 | BIRC5 | BNIP2 | BRCA1 | BUB1 | BUB1B | CASP3 | CCK | CDK1 | CIDEC | CKAP2 | CSNK2A1 | CST3 | CYCT | DAPK1 | DDIAS | DYRK2 | ELMO3 | ESPL1 | FADD | FAIM2 | FGFR3 | G2E3 | GAPDH | GDF6 | GSN | HINT2 | IAPP | IKBKG | IL2RA | ITPR1 | KIF1B | KLF11 | LGALS1 | LMNB1 | LTA | MAP3K10 | MAPK1 | MAPK3 | MCM2 | MELK | NLRP2 | NOTCH2 | OGT | PAK6 | PARM1 | PARP1 | PCSK9 | PDCL3 | PIDD1 | PLAGL1 | PPP2R2B | PRKCE | PTK2B | PTPRH | RABEP1 | RFFL | RIPK1 | RMDN3 | RPS6KA3 | SCML2 | SEMA3A | SEMA6A | SGMS1 | SLC5A11 | SNCA | SP110 | SQSTM1 | SUDS3 | TCHP | TIA1 | TNF | TNFRSF9 | TNFSF12 | TOPAZ1 | TOX3 | TPX2 | TRAIP | TRP53 | VDAC1 | WWOX | XIAP | ZFP369
1
24. 2,2',3',4,4',5-hexachlorobiphenyl necroptotic process TNF 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [TNF protein results in increased necroptotic process] 1: Mus musculus 3T3-L1 Cells
3 genes: BIRC3 | RIPK1 | TRP53
1
25. 2,2',3',4,4',5-hexachlorobiphenyl nucleus organization TNF 2,2',3',4,4',5-hexachlorobiphenyl inhibits the reaction [TNF protein results in decreased nucleus organization] 1: Mus musculus 3T3-L1 Cells
7 genes: BIN1 | CEP55 | CHMP4C | LBR | MAP7 | PRM1 | VPS4A
1
26. 2,2',3',4,4',5-hexachlorobiphenyl cell death 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | methylmercuric chloride [methylmercuric chloride co-treated with Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane co-treated with Hexachlorobenzene co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased cell death 1: Mus musculus Cerebral Cortex | Neurons | Cells, Cultured
4 genes: ALS2 | HTR2A | MAP3K10 | PTGER3
1
27. 2,2',3',4,4',5-hexachlorobiphenyl cell death 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Dopamine | Hexachlorobenzene | methylmercuric chloride Dopamine inhibits the reaction [[methylmercuric chloride co-treated with Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane co-treated with Hexachlorobenzene co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased cell death] 1: Mus musculus Cerebral Cortex | Neurons | Cells, Cultured
4 genes: ALS2 | HTR2A | MAP3K10 | PTGER3
1
28. 2,2',3,4',5,5',6-heptachlorobiphenyl hypermethylation of CpG island 2,2',3,4',5,5',6-heptachlorobiphenyl affects hypermethylation of CpG island 1: Homo sapiens Leukocytes   1
29. 2,2',3,5,5',6-hexachlorobiphenyl positive regulation of cell death KRT18 | Polychlorinated Biphenyls [[Polychlorinated Biphenyls results in increased abundance of 2,2',3,5,5',6-hexachlorobiphenyl] which results in increased expression of KRT18 protein] which results in increased positive regulation of cell death 1: Homo sapiens Liver | Hepatocytes   1
30. 2,2',3,5',6-pentachlorobiphenyl production of molecular mediator of immune response 2,2',3,5',6-pentachlorobiphenyl results in increased production of molecular mediator of immune response 1: Homo sapiens Blood   1
31. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death Resveratrol Resveratrol inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death] 1: Homo sapiens Neurons | Cell Line, Tumor   1
32. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death Resveratrol Resveratrol inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death] 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured   1
33. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death Resveratrol | SIRT1 SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death]] 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured   1
34. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death REST REST protein promotes the reaction [2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death] 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured   1
35. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death 2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death 1: Homo sapiens Neurons | Cell Line, Tumor   1
36. 2,2',3,5',6-pentachlorobiphenyl positive regulation of neuron death 2,2',3,5',6-pentachlorobiphenyl results in increased positive regulation of neuron death 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured   1
37. 2,2',3,5',6-pentachlorobiphenyl dopamine biosynthetic process 2,2',3,5',6-pentachlorobiphenyl affects dopamine biosynthetic process 1: Rattus norvegicus PC12 Cells 1 gene: TH 1
38. 2,2',3,5',6-pentachlorobiphenyl dopamine secretion 2,2',3,5',6-pentachlorobiphenyl affects dopamine secretion 1: Rattus norvegicus PC12 Cells   1
39. 2,2',3,5',6-pentachlorobiphenyl calcium ion homeostasis 2,2',3,5',6-pentachlorobiphenyl affects calcium ion homeostasis 1: Rattus norvegicus Cerebral Cortex | Microsomes 1 gene: NR3C1 1
40. 2,2',3,5',6-pentachlorobiphenyl calcium ion homeostasis 1,1'-diheptyl-4,4'-bipyridinium 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes 1 gene: NR3C1 1
41. 2,2',3,5',6-pentachlorobiphenyl calcium ion homeostasis Heparin Heparin inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes 1 gene: NR3C1 1
42. 2,2',4,4',5-pentachlorobiphenyl production of molecular mediator of immune response 2,2',4,4',5-pentachlorobiphenyl results in increased production of molecular mediator of immune response 1: Homo sapiens Blood   1
43. 2,2',4,4',5-pentachlorobiphenyl hormone metabolic process 2,2',4,4',5-pentachlorobiphenyl affects hormone metabolic process 1: Homo sapiens Blood   1
44. 2,2',4,4',5-pentachlorobiphenyl regulation of thyroid-stimulating hormone secretion 2,2',4,4',5-pentachlorobiphenyl affects regulation of thyroid-stimulating hormone secretion 1: Homo sapiens Serum   1
45. 2,2',4,4',5-pentachlorobiphenyl thyroid hormone metabolic process 2,2',4,4',5-pentachlorobiphenyl affects thyroid hormone metabolic process 1: Homo sapiens Serum   1
46. 2,2',4,4',5-pentachlorobiphenyl hypermethylation of CpG island 2,2',4,4',5-pentachlorobiphenyl affects hypermethylation of CpG island 1: Homo sapiens Leukocytes   1
47. 2,2',4,6,6'-pentachlorobiphenyl apoptotic process 2,2',4,6,6'-pentachlorobiphenyl results in increased apoptotic process 1: Homo sapiens U937 Cells
6 genes: AKT1 | CASP3 | MAPK1 | MAPK3 | NCF1 | NFKB1
1
48. 2,2',4,6,6'-pentachlorobiphenyl apoptotic DNA fragmentation 2,2',4,6,6'-pentachlorobiphenyl results in increased apoptotic DNA fragmentation 1: Homo sapiens U937 Cells
2 genes: CASP3 | REL
1
49. 2,2',4,6,6'-pentachlorobiphenyl positive regulation of cell migration 2,2',4,6,6'-pentachlorobiphenyl results in increased positive regulation of cell migration 1: Homo sapiens Endometrium | Stromal Cells | Cells, Cultured
4 genes: EGFR | MAPK1 | MAPK8 | MMP3
1
50. 2,2',4,6,6'-pentachlorobiphenyl actin cytoskeleton organization 2,2',4,6,6'-pentachlorobiphenyl affects actin cytoskeleton organization 1: Homo sapiens Endometrium | Stromal Cells | Cells, Cultured   1
1–50 of 1,257 results.