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Chemical Heterocyclic Compounds, Fused-Ring

1–50 of 28,288 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine cell proliferation resveratrol | Sodium Fluoride 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine inhibits the reaction [resveratrol inhibits the reaction [Sodium Fluoride results in decreased cell proliferation]] 1: Mus musculus Ameloblasts | Cell Line   1
2. 10-(alpha-diethylaminopropionyl)phenothiazine positive regulation of cell death 10-(alpha-diethylaminopropionyl)phenothiazine results in increased positive regulation of cell death 1: Homo sapiens Hepatocytes | Cell Line, Tumor   1
3. 10-decarbamoylmitomycin C apoptotic process 10-decarbamoylmitomycin C results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor
4 genes: CASP3 | CASP9 | CHEK1 | TP53
1
4. 10-hydroxywarfarin xenobiotic glucuronidation 10-hydroxywarfarin results in decreased xenobiotic glucuronidation 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
5. 10-hydroxywarfarin xenobiotic glucuronidation Zidovudine [10-hydroxywarfarin results in decreased xenobiotic glucuronidation] which results in decreased glucuronidation of Zidovudine 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
6. 10-propargyl-10-deazaaminopterin apoptotic process gemcitabine [10-propargyl-10-deazaaminopterin co-treated with gemcitabine] results in increased apoptotic process 1: Mus musculus Tumor Cells, Cultured 1 gene: CASP3 1
7. 10-propargyl-10-deazaaminopterin apoptotic process Cytarabine [Cytarabine co-treated with 10-propargyl-10-deazaaminopterin] results in increased apoptotic process 1: Homo sapiens Tumor Cells, Cultured 1 gene: CASP3 1
8. 10-propargyl-10-deazaaminopterin cell cycle gemcitabine [10-propargyl-10-deazaaminopterin co-treated with gemcitabine] affects cell cycle 1: Mus musculus Tumor Cells, Cultured   1
9. 1,10-phenanthroline membrane lipid catabolic process Asbestos, Serpentine 1,10-phenanthroline inhibits the reaction [Asbestos, Serpentine results in increased membrane lipid catabolic process] 1: Rattus norvegicus Lung | Pulmonary Alveoli | Macrophages   1
10. 1,10-phenanthroline apoptotic process MBTPS2 [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which results in increased apoptotic process 1: Homo sapiens Adipose Tissue | Cell Line, Tumor
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
11. 1,10-phenanthroline apoptotic process 2,6-di-tert-butyl-4-methylphenol 1,10-phenanthroline inhibits the reaction [2,6-di-tert-butyl-4-methylphenol results in increased apoptotic process] 1: Homo sapiens U937 Cells
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
12. 1,10-phenanthroline apoptotic process Tetrachlorodibenzodioxin 1,10-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin results in decreased apoptotic process] 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
13. 1,10-phenanthroline apoptotic process Hydrogen Peroxide | Nitroprusside 1,10-phenanthroline inhibits the reaction [Hydrogen Peroxide promotes the reaction [Nitroprusside results in increased apoptotic process]] 1: Homo sapiens Cell Line, Tumor
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
14. 1,10-phenanthroline apoptotic process Iron Compounds 1,10-phenanthroline inhibits the reaction [Iron Compounds results in increased apoptotic process] 1: Rattus norvegicus Hepatocytes | Cells, Cultured
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
15. 1,10-phenanthroline cell proliferation 1,10-phenanthroline results in decreased cell proliferation 1: Mus musculus B-Lymphocytes | Cells, Cultured
8 genes: ACE | CYP1A1 | ENPEP | ERCC2 | MIF | PDK1 | STAT3 | VEGFA
1
16. 1,10-phenanthroline apoptotic process 9,10-phenanthrenequinone 1,10-phenanthroline inhibits the reaction [9,10-phenanthrenequinone results in increased apoptotic process] 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
17. 1,10-phenanthroline positive regulation of cell death 1,10-phenanthroline results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
2 genes: AKR1C3 | EGR1
1
18. 1,10-phenanthroline positive regulation of cell death 1,10-phenanthroline results in increased positive regulation of cell death 1: Homo sapiens Prostate | Cell Line, Tumor
2 genes: AKR1C3 | EGR1
1
19. 1,10-phenanthroline positive regulation of cell death 1,10-phenanthroline results in increased positive regulation of cell death 1: Homo sapiens HT29 Cells
2 genes: AKR1C3 | EGR1
1
20. 1,10-phenanthroline positive regulation of cell death Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
2 genes: AKR1C3 | EGR1
1
21. 1,10-phenanthroline positive regulation of cell death Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased positive regulation of cell death 1: Homo sapiens Prostate | Cell Line, Tumor
2 genes: AKR1C3 | EGR1
1
22. 1,10-phenanthroline positive regulation of cell death Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased positive regulation of cell death 1: Homo sapiens Ovary | Cell Line, Tumor
2 genes: AKR1C3 | EGR1
1
23. 1,10-phenanthroline positive regulation of cell death Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased positive regulation of cell death 1: Homo sapiens HT29 Cells
2 genes: AKR1C3 | EGR1
1
24. 1,10-phenanthroline positive regulation of reactive oxygen species biosynthetic process 1,10-phenanthroline results in increased positive regulation of reactive oxygen species biosynthetic process 1: Homo sapiens Ovary | Cell Line, Tumor   1
25. 1,10-phenanthroline positive regulation of reactive oxygen species biosynthetic process Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased positive regulation of reactive oxygen species biosynthetic process 1: Homo sapiens Ovary | Cell Line, Tumor   1
26. 1,10-phenanthroline removal of superoxide radicals Copper | phthalic acid [Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased removal of superoxide radicals  
2 genes: SOD1 | SOD2
1
27. 1,10-phenanthroline removal of superoxide radicals Copper | Hydrogen Peroxide | phthalic acid [[Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased removal of superoxide radicals] which results in increased chemical synthesis of Hydrogen Peroxide  
2 genes: SOD1 | SOD2
1
28. 1,10-phenanthroline hydrogen peroxide catabolic process Copper | imidazole | phthalic acid [[Copper binds to phthalic acid binds to 1,10-phenanthroline] which co-treated with imidazole] results in increased hydrogen peroxide catabolic process  
2 genes: CAT | GPX3
1
29. 1,10-phenanthroline hydrogen peroxide catabolic process Manganese | phthalic acid [Manganese binds to phthalic acid binds to 1,10-phenanthroline] which results in increased hydrogen peroxide catabolic process  
2 genes: CAT | GPX3
1
30. 1,10-phenanthroline positive regulation of cell death 1,10-phenanthroline results in increased positive regulation of cell death 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: AKR1C3 | EGR1
1
31. 1,10-phenanthroline positive regulation of retinoic acid receptor signaling pathway 1,10-phenanthroline results in increased positive regulation of retinoic acid receptor signaling pathway 1: Mus musculus Embryo, Mammalian | Fibroblasts | Cell Line   1
32. 1,10-phenanthroline lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | NADP | Sodium Chloride 1,10-phenanthroline promotes the reaction [[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] 1: Rattus norvegicus     1
33. 1,10-phenanthroline lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | Malondialdehyde | NADP | Sodium Chloride 1,10-phenanthroline promotes the reaction [[[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus     1
34. 1,10-phenanthroline apoptotic process Antimycin A 1,10-phenanthroline affects the reaction [Antimycin A results in increased apoptotic process] 1: Rattus norvegicus PC12 Cells
12 genes: AHR | ALDOC | APP | BNIP3L | ERCC2 | GAPDH | HIF3A | HMOX1 | MAPK1 | MAPK3 | NR3C1 | TRP53
1
35. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons   1
36. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane locomotory behavior 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased locomotory behavior] 1: Mus musculus  
2 genes: SLC6A3 | TH
1
37. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: CASP1 | IL1A | TLR4
1
38. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: ATF4 | CASP3 | DDIT3
1
39. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons 1 gene: CASP8 1
40. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
41. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation] 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
42. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane apoptotic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased apoptotic process 1: Homo sapiens Kidney | Cell Line, Tumor
12 genes: BCL2 | BID | BIRC5 | CASP3 | CASP7 | CASP8 | DDIT3 | EP300 | NR4A1 | PARP1 | RPS6KB1 | XBP1
1
43. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Kidney | Cell Line, Tumor   1
44. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens Breast | Cell Line, Tumor
2 genes: ITGB1 | ITGB3
1
45. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens MCF-7 Cells
2 genes: ITGB1 | ITGB3
1
46. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
47. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
48. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration ITGB1 ITGB1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
49. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration TGFB1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [TGFB1 protein results in increased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
50. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane DNA damage response, detection of DNA damage 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: PARP1 1
1–50 of 28,288 results.