Name | Leflunomide |
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CAS Type 1 Name | 4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)- |
Equivalent Terms | Arava | HWA486 | HWA 486 | HWA-486 | N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide | SU101 |
CAS Registry Number | 75706-12-6 |
Definition | An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. |
Structure | ![]() |
Top Interacting Genes |
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MeSH® ID | D000077339 |
External Links |
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Chemicals
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Heterocyclic Compounds
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