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Chemical Acetazolamide

Name Acetazolamide
CAS Type 1 Name Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-
Equivalent Terms Acetadiazol | Acetazolam | Acetazolamide, Monosodium Salt | Acetazolamide Sodium, (Sterile) | AkZol | Ak Zol | Ak-Zol | ApoAcetazolamide | Apo Acetazolamide | Apo-Acetazolamide | Défiltran | Diacarb | Diamox | Diuramide | Edemox | Glauconox | Glaupax | HumaZolamide | Huma Zolamide | Huma-Zolamide
CAS Registry Number 59-66-5
Definition One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Structure Acetazolamide
Top Interacting
Genes
MeSH® ID D000086
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Sulfur Compounds Has associated genes Has associated diseases Has associated exposure references Thiazoles Has associated genes Has associated diseases Has associated exposure references Thiadiazoles Has associated genes Has associated diseases Acetazolamide Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Azoles Has associated genes Has associated diseases Has associated exposure references Thiazoles Has associated genes Has associated diseases Has associated exposure references Thiadiazoles Has associated genes Has associated diseases Acetazolamide Has associated genes Has associated diseases

Top ↑ Descendants

Acetazolamide Has associated genes Has associated diseases
  5-valproylamido-1,3,4-thiadiazole-2-sulfonamide
  acetazolamide adipate ethyl ester
  N-bromoacetazolamide
  Ulcosilvanil
  WP 1