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Chemical Adjuvants, Immunologic

Name Adjuvants, Immunologic
Equivalent Terms Adjuvant, Immunologic | Adjuvant, Immunological | Adjuvants, Immunological | Immunoactivators | Immunoadjuvants | Immunologic Adjuvant | Immunologic Adjuvants | Immunological Adjuvant | Immunological Adjuvants | Immunopotentiators | Immunostimulants
Definition Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
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Genes
MeSH® ID D000276
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ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Physiological Effects of Drugs Has associated genes Has associated diseases Has associated exposure references Immunologic Factors Has associated genes Has associated diseases Adjuvants, Immunologic Has associated genes Has associated diseases

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