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Chemical Androstenes

These diseases are associated with Androstenes or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 7,790 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Testosterone Breast Neoplasms M
148 genes: ABCG2 | ABL1 | ACHE | AGR2 | AHR | AKAP12 | AKT1 | AKT2 | ANGPTL4 | APOBEC3B | AR | AREG | ARRDC3 | ATM | AURKA | BARD1 | BAX | BCHE | BCL2 | BIRC5 | BMP2 | BMP4 | BRCA1 | BRCA2 | BRIP1 | C10ORF10 | CASP8 | CAV1 | CCND1 | CCNE1 | CDKN1B | CENPF | CHEK2 | CLDN4 | COMT | CSF1 | CSF1R | CTNNB1 | CXCL8 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1B1 | CYP2B1 | CYP3A4 | DNMT1 | DNMT3A | DNMT3B | E2F1 | EDNRB | EGF | EGFR | EPB41L3 | ESR1 | ESR2 | ESRRA | EVL | EZH2 | FGFR1 | FGFR2 | FHL2 | FOS | FOXA1 | FOXM1 | FOXP3 | FST | GPNMB | GPX2 | H2AFX | HES1 | HHEX | HIF1A | HMMR | HMOX1 | HOXB13 | HP | HRAS | IFNG | IGF1 | IGF1R | IGFBP5 | IGFBP7 | IL1B | IL6 | JAG1 | KDR | LEPR | MIR10A | MIR132 | MIR141 | MIR206 | MIR29A | MKI67 | MME | MMP3 | MTHFR | NAT2 | NDRG1 | NFKBIA | NOS2 | NOS3 | NOTCH1 | NOTCH2 | NR2F1 | PAEP | PAK1 | PER3 | PIK3CA | PIM1 | PRC1 | PTEN | PTGS1 | PTGS2 | PTHLH | RAD51 | RAD51B | RAD51C | RAD54L | RAF1 | RELA | RPS6 | SHMT1 | SLC22A18 | SLC2A5 | SNAI2 | SNCG | SOD2 | SRC | STAT5A | STC2 | STMN1 | SYNE1 | TBX3 | TERT | TFRC | TGM2 | THBS1 | TNF | TNFSF10 | TOP2A | TOX3 | TP53 | TRP53 | TYMS | UBE2C | UMPS | XRCC2 | XRCC3
122.26 178
2. Testosterone Polycystic Ovary Syndrome M
41 genes: AKR1C1 | AKR1C3 | ANLN | ASPM | AZGP1 | BAX | BCL2 | CCNB1 | CCNE2 | CDC6 | CEP55 | CKS2 | CLDN4 | CYP19A1 | ERRFI1 | FOXP3 | FSHR | FST | GDF9 | HELLS | HMMR | HSD3B1 | HSD3B2 | INS | LHB | LIFR | MAD2L1 | MTNR1B | PBK | RACGAP1 | RRM2 | S100P | SCNN1A | SRD5A1 | SRSF10 | STAR | TFRC | TONSL | TOP2A | TRPV6 | TTK
45.94 15
3. Testosterone Mammary Neoplasms, Animal M
37 genes: ANXA2 | BASP1 | BRCA1 | CCND1 | CDC42 | COL5A1 | COMT | DBI | DUSP6 | EGFR | ESR1 | ESR2 | GATA3 | GNAI2 | HNRNPA1 | HRAS | IL6ST | INS1 | INSIG1 | LIN7A | MGP | PIK3R1 | PPARA | PRL | PRLR | RPL6 | S100A8 | SCD | SGK1 | SNCG | SNRPD3 | SOX9 | STAT5A | STMN1 | TMEM37 | TSC22D1 | XDH
32.87 18
4. Testosterone Reperfusion Injury M
34 genes: BCL2 | CAT | CCL2 | CD36 | CDKN1A | CXCL8 | CYP3A9 | EDN1 | EFNB2 | EGF | EGR1 | FOS | GHRL | HBEGF | HMOX1 | HSPB1 | ICAM1 | IL12A | IL1B | IL6 | KDR | NOS2 | NOS3 | PPARA | PPARG | PTEN | PTGS1 | PTGS2 | RELA | SOD2 | TERT | THBS1 | TNF | XDH
30.52 40
5. Methyltestosterone Prostatic Neoplasms M
10 genes: AR | BAX | CASP9 | CYP19A1 | CYP1A1 | ESR1 | KLK3 | NCOA1 | NR3C1 | SRD5A2
25.00 32
6. wortmannin Fatty Liver M
13 genes: APOB | BIRC3 | CXCL8 | CYCS | CYP2E1 | INS | LEP | PPARA | PPARD | SIRT1 | SOD2 | STS | TNF
22.96 17
7. Testosterone Insulin Resistance M
29 genes: ADIPOQ | AR | C3 | CD36 | CPE | EGFR | GH1 | GPX3 | HMOX1 | HSD11B1 | IGFBP2 | INS | INS1 | INSR | IRS1 | LEPR | NOS3 | NR4A1 | PIK3R1 | PPARA | PPARG | PRKAA1 | PTEN | RETN | SCD1 | SLC2A4 | SREBF1 | SREBF2 | TNF
22.75 37
8. Testosterone Brain Ischemia M
29 genes: ACE | ALB | CASP3 | CASP9 | CAT | CCL2 | CEBPB | CXCL10 | EGR1 | F5 | HIF1A | ICAM1 | IL18 | IL1A | IL1B | IL6 | MAP2K1 | MAPK1 | MAPK3 | MTHFR | NFKB1 | NFKBIA | NOS2 | PTGS2 | RELA | SOD2 | TNF | TNFRSF1A | TP53
21.82 17
9. Testosterone Glioblastoma M
20 genes: BCHE | CXCL8 | DUSP6 | EGF | EGFR | HES1 | HIF1A | IL1B | JAG1 | MET | MYC | NDRG1 | NOTCH1 | NOTCH2 | PIM1 | PROM1 | PTK2 | TGM2 | TNFSF10 | VEGFA
15.70 18
10. Testosterone Weight Gain M
27 genes: ACADM | ADIPOQ | ANXA2 | CAV1 | CD36 | FEZ2 | GH | GH1 | GHRL | GSN | HTR2C | IGFBP5 | INSIG2 | ME1 | MMP12 | MPRIP | NID1 | PIK3CA | POMC | PTRF | RYK | SCD1 | SERPINB6A | SPARC | TNF | VIM | ZWILCH
14.77 13
11. Testosterone Atherosclerosis M
24 genes: ABCA1 | ADIPOQ | AGT | AHR | CCL2 | ESR1 | FASLG | GSTM1 | HP | ICAM1 | IFNG | IGF2 | IL6 | NOS2 | NOS3 | PPARG | PTGS2 | SERPINE1 | SOCS3 | SOD2 | TLR4 | TNF | TTPA | VEGFA
12.51 21
12. Testosterone Propionate Myocardial Infarction M
7 genes: AGT | CAT | ESR1 | IL1B | IL6 | REN | TNF
12.10 9
13. Testosterone Propionate Prostatic Intraepithelial Neoplasia M
3 genes: AR | ESR1 | GSTP1
11.91 4
14. Dehydroepiandrosterone Liver Neoplasms, Experimental M
8 genes: BCL2 | BCL2L1 | CYP1A2 | CYP2E1 | KRAS | NR1I3 | RB1 | TP53
11.84 9
15. Testosterone Propionate Carcinoma, Hepatocellular M
7 genes: AR | CYP17A1 | ESR1 | GSTP1 | IGF1R | IL6 | TH
11.68 10
16. Testosterone Liver Neoplasms M
34 genes: ABL1 | AHR | ANXA2 | ATF3 | CDKN1B | CTNNB1 | CYP2E1 | EFNB2 | ESR1 | EXOSC2 | FST | GNMT | GPX3 | GSTM1 | HMOX1 | HRAS | IGF2 | IL12A | MAPK14 | MIR29A | MYC | NAT2 | NDRG1 | NR1H4 | NR1I3 | PPARA | PPARG | RAF1 | SCD | SERPINE1 | TNF | TNFSF10 | TP53 | TTC39A
11.46 40
17. Dehydroepiandrosterone Liver Neoplasms M
8 genes: CDKN2A | CYP2E1 | ESR1 | KRAS | NAT2 | NR1I3 | PPARA | TP53
11.40 15
18. Testosterone Prostatic Intraepithelial Neoplasia M
7 genes: AR | CDKN1B | DNMT1 | ESR1 | ESR2 | PIM1 | PTEN
10.76 7
19. Testosterone Hypertension M
64 genes: ABCC1 | ACE | ADIPOQ | ADRA2A | ADRB1 | AGT | AGTR1 | AGTR2 | AHR | ALB | AR | ATP1A2 | ATP2B1 | AVP | BCL2 | CAT | CAV1 | CD36 | COL1A1 | COL3A1 | CTGF | CYP1A1 | ECE1 | EDN1 | EDNRA | EPO | F12 | FOS | GAL | GNRH1 | HIF1A | HMOX1 | HP | HSD11B1 | HSD11B2 | ICAM1 | IGF1 | INS | KCNJ1 | LEPR | LHB | MTOR | NCF1 | NOS2 | NOS3 | NPR1 | NR3C1 | POMC | PPARA | PPARG | PRKCD | PTEN | PTGS2 | RELA | RPS6KB1 | SCNN1A | SELP | SERPINE1 | SOD2 | TGFB1 | TGM2 | TNF | TP53 | UCN
10.49 213
20. Testosterone Burns M
7 genes: IL1A | IL1B | IL6 | NOS2 | POMC | PTGS2 | TNF
10.16 5
21. wortmannin Necrosis M
12 genes: AGT | AIFM1 | BCL2 | CYP2E1 | IFNG | IL1B | IL6 | INS1 | MYCN | NOS2 | SOD2 | TNF
9.69 17
22. Dehydroepiandrosterone Polycystic Ovary Syndrome M
5 genes: BAX | BCL2 | CYP19A1 | HSD3B1 | SRD5A1
9.25 6
23. Testosterone Pain M
11 genes: AKT1 | ALB | AVP | BDKRB1 | COMT | CRH | EDN1 | NTSR1 | PENK | POMC | TNF
9.21 16
24. Testosterone Propionate Insulin Resistance M
4 genes: AR | INS | INSR | TNF
8.79 7
25. Testosterone Non-alcoholic Fatty Liver Disease M
11 genes: ACE | ADIPOQ | CD14 | CYP17A1 | FAS | GSTM1 | IL1A | PPARA | SREBF1 | STC2 | TGFB1
8.41 9
26. Testosterone Status Epilepticus M
22 genes: ABCC2 | CASP3 | CASP8 | CAT | CCL2 | CRH | EPO | FOS | HMOX1 | HSPB1 | JUNB | KCNK5 | NOS1 | NOS2 | NTRK2 | PTGS2 | SCN8A | SLC8A1 | SNTA1 | SRC | TNF | VEGFA
8.05 27
27. Dehydroepiandrosterone Sulfate Autistic Disorder M
3 genes: BCL2 | POMC | PRL
7.33 5
28. Testosterone Propionate Hypertension M
7 genes: AGT | AR | CAT | INS | LHB | REN | TNF
7.28 77
29. Testosterone Aortic Aneurysm, Abdominal M
5 genes: AGT | AGTR1 | NCF1 | PTGS2 | SOD2
7.17 5
30. Androstenedione Alcoholism M
2 genes: FSHB | LHB
6.98 1
31. Testosterone Propionate Adenocarcinoma M
4 genes: ESR1 | IL1B | PGR | TNF
6.93 6
32. Testosterone Propionate Polycystic Ovary Syndrome M
3 genes: FSHR | INS | LHB
6.66 5
33. fluticasone Anemia M
3 genes: CSF2 | IL2 | TNF
6.64 5
34. Testosterone Propionate Hyperinsulinism M
2 genes: INS | INSR
6.55 7
35. Testosterone Parkinson Disease M
19 genes: BST1 | CP | CYP2E1 | DDC | DDIT4 | EDN1 | GFAP | GSTM1 | HMOX1 | HSPA9 | IGF1R | IGF2 | IL6 | INS | INSR | RPL6 | SLC6A3 | SOD2 | TNF
6.45 18
36. Testosterone Fibrosis M
17 genes: ADRA2A | AGT | ALB | CCND2 | CHRNA1 | COL1A1 | COL3A1 | CYP19A1 | HMOX1 | LEPR | MIR133A | NPR1 | PTGS2 | SOD2 | TGFB1 | THBS1 | TNF
6.17 20
37. Methyltestosterone Carcinoma, Hepatocellular M
3 genes: AR | CYP1A1 | ESR1
6.16 6
38. Testosterone Child Development Disorders, Pervasive M
9 genes: CNTNAP2 | GRIN2B | JARID2 | MTNR1B | NRXN1 | NRXN2 | NTSR1 | RAI1 | SOX9
6.16 12
39. Methandrostenolone Carcinoma, Hepatocellular M
2 genes: AR | FST
5.80 4
40. Testosterone Kidney Neoplasms M
12 genes: AURKA | CCND1 | CDKN1B | CYP1A1 | EIF4EBP1 | MAPK1 | MAPK3 | NDRG1 | PTGS2 | RAF1 | TNFSF10 | TSC2
5.78 10
41. Dehydroepiandrosterone Sulfate Hepatomegaly M
2 genes: NR1I2 | PPARA
5.48 3
42. loteprednol etabonate Ocular Hypertension M   1 gene: NR3C1 5.11 2
43. Testosterone Prenatal Exposure Delayed Effects M
4 genes: ADORA1 | ATM | CTGF | MYOD1
5.08 8
44. Finasteride Depressive Disorder M
2 genes: CRH | POMC
5.00 4
45. Dehydroepiandrosterone Diabetes Mellitus, Type 1 M
2 genes: CAT | NOS3
4.92 3
46. Testosterone Malaria M
7 genes: CD36 | CISH | HP | ICAM1 | NOS2 | SLC4A1 | TNF
4.92 4
47. Testosterone Nervous System Diseases M
23 genes: ABCC2 | ABCG2 | ACHE | ATF3 | CASP3 | CASP9 | CYP2C9 | FOS | FOXG1 | GFAP | MTHFR | NOS1 | NOTCH1 | PENK | PTGS2 | SCN8A | SERPINE1 | SHMT1 | SLC6A3 | TNF | TRP53 | TTPA | TYMS
4.80 20
48. Testosterone Angina Pectoris M   1 gene: AVP 4.72 3
49. Testosterone Propionate Hyperglycemia M
2 genes: INS | INSR
4.44 4
50. drospirenone and ethinyl estradiol combination Thromboembolism M   1 gene: F2 4.40 2
1–50 of 7,790 results.