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Chemical Androstenes

These diseases are associated with Androstenes or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 8,884 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Testosterone Breast Neoplasms M
160 genes: ABCC1 | ABCG2 | ABL1 | ACHE | ACTA2 | AGR2 | AHR | AKAP12 | AKT1 | AKT2 | ANGPTL4 | APOBEC3B | AR | AREG | ARRDC3 | ATM | AURKA | BARD1 | BAX | BCHE | BCL2 | BIRC5 | BMP2 | BMP4 | BRCA1 | BRCA2 | BRIP1 | C10ORF10 | CASP8 | CAT | CAV1 | CCND1 | CCNE1 | CDKN1B | CENPF | CHEK2 | CLDN4 | COMT | CSF1 | CSF1R | CTNNB1 | CXCL8 | CXCL9 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1B1 | CYP2B1 | CYP3A4 | DNMT1 | DNMT3A | DNMT3B | E2F1 | EDNRB | EGF | EGFR | EPB41L3 | ESR1 | ESR2 | ESRRA | EVL | EXO1 | EZH2 | FGFR1 | FGFR2 | FHL2 | FOS | FOXA1 | FOXM1 | FOXP3 | FST | GNAI2 | GPNMB | GPX2 | H2AFX | HES1 | HHEX | HIF1A | HMMR | HMOX1 | HOXB13 | HP | HRAS | IDO1 | IFNG | IGF1 | IGF1R | IGFBP5 | IGFBP7 | IL1B | IL6 | JAG1 | KDR | LEPR | MDM2 | MIR10A | MIR132 | MIR141 | MIR206 | MIR29A | MKI67 | MME | MMP3 | MTHFR | NAT2 | NDRG1 | NFKBIA | NOS2 | NOS3 | NOTCH1 | NOTCH2 | NR2F1 | PAEP | PAK1 | PER3 | PGR | PIK3CA | PIM1 | PRC1 | PTEN | PTGS1 | PTGS2 | PTHLH | RAD51 | RAD51B | RAD51C | RAD54L | RAF1 | RARA | RELA | RPS6 | SHMT1 | SLC22A18 | SLC2A5 | SNAI2 | SNCG | SOD2 | SRC | STAT5A | STC2 | STMN1 | SYNE1 | TBX3 | TERT | TFRC | TGM2 | THBS1 | TNF | TNFSF10 | TOP2A | TOX3 | TP53 | TRP53 | TYMS | UBE2C | UMPS | VIM | WHSC1 | XRCC2 | XRCC3
144.44 196
2. Testosterone Polycystic Ovary Syndrome M
41 genes: AKR1C1 | AKR1C3 | ANLN | ASPM | AZGP1 | BAX | BCL2 | CCNB1 | CCNE2 | CDC6 | CEP55 | CKS2 | CLDN4 | CYP19A1 | ERRFI1 | FOXP3 | FSHR | FST | GDF9 | HELLS | HMMR | HSD3B1 | HSD3B2 | INS | LHB | LIFR | MAD2L1 | MTNR1B | PBK | RACGAP1 | RRM2 | S100P | SCNN1A | SRD5A1 | SRSF10 | STAR | TFRC | TONSL | TOP2A | TRPV6 | TTK
49.19 15
3. Testosterone Reperfusion Injury M
44 genes: AGT | BCL2 | CASP3 | CASP8 | CAT | CCL2 | CD36 | CDKN1A | CXCL8 | CYP3A9 | EDN1 | EFNB2 | EGF | EGR1 | FOS | GHRL | HBEGF | HMOX1 | HSPB1 | ICAM1 | IL12A | IL1A | IL1B | IL6 | IL6RA | IL6ST | KDR | NOS2 | NOS3 | PPARA | PPARG | PTEN | PTGS1 | PTGS2 | RELA | SOCS1 | SOD2 | TERT | THBS1 | TLR2 | TLR4 | TNF | VIM | XDH
46.09 46
4. Testosterone Mammary Neoplasms, Animal M
38 genes: ANXA2 | BASP1 | BRCA1 | CCND1 | CDC42 | COL5A1 | COMT | DBI | DUSP6 | EGFR | ESR1 | ESR2 | GATA3 | GNAI2 | HNRNPA1 | HRAS | IL6ST | INS1 | INSIG1 | LIN7A | MGP | PGR | PIK3R1 | PPARA | PRL | PRLR | RPL6 | S100A8 | SCD | SGK1 | SNCG | SNRPD3 | SOX9 | STAT5A | STMN1 | TMEM37 | TSC22D1 | XDH
37.30 18
5. wortmannin Fatty Liver M
15 genes: APOB | BIRC3 | CAT | CXCL8 | CYCS | CYP2E1 | INS | LEP | PPARA | PPARD | SERPINE1 | SIRT1 | SOD2 | STS | TNF
25.65 21
6. Methyltestosterone Prostatic Neoplasms M
10 genes: AR | BAX | CASP9 | CYP19A1 | CYP1A1 | ESR1 | KLK3 | NCOA1 | NR3C1 | SRD5A2
24.73 38
7. Testosterone Insulin Resistance M
31 genes: ADIPOQ | AHR | AR | C3 | CD36 | CPE | EGFR | GH1 | GPX3 | HMOX1 | HSD11B1 | IGFBP2 | INS | INS1 | INSR | IRS1 | LEPR | NOS3 | NR4A1 | PIK3R1 | PPARA | PPARG | PRKAA1 | PTEN | RETN | SCD1 | SLC2A4 | SOD2 | SREBF1 | SREBF2 | TNF
24.46 41
8. Testosterone Brain Ischemia M
29 genes: ACE | ALB | CASP3 | CASP9 | CAT | CCL2 | CEBPB | CXCL10 | EGR1 | F5 | HIF1A | ICAM1 | IL18 | IL1A | IL1B | IL6 | MAP2K1 | MAPK1 | MAPK3 | MTHFR | NFKB1 | NFKBIA | NOS2 | PTGS2 | RELA | SOD2 | TNF | TNFRSF1A | TP53
23.88 17
9. Testosterone Glioblastoma M
24 genes: BCHE | CTSK | CXCL8 | DUSP6 | EGF | EGFR | GDNF | H2AFX | HES1 | HIF1A | IL1B | JAG1 | MET | MYC | NDRG1 | NOTCH1 | NOTCH2 | PIM1 | PROM1 | PTK2 | RUNX1 | TGM2 | TNFSF10 | VEGFA
22.24 23
10. wortmannin Necrosis M
17 genes: AGT | AHR | AIFM1 | BCL2 | CAT | CYP2E1 | GSTP1 | HMGB1 | IFNG | IL17A | IL1B | IL6 | INS1 | MYCN | NOS2 | SOD2 | TNF
16.42 24
11. Testosterone Weight Gain M
28 genes: ACADM | ACE | ADIPOQ | ANXA2 | CAV1 | CD36 | FEZ2 | GH | GH1 | GHRL | GSN | HTR2C | IGFBP5 | INSIG2 | ME1 | MMP12 | MPRIP | NID1 | PIK3CA | POMC | PTRF | RYK | SCD1 | SERPINB6A | SPARC | TNF | VIM | ZWILCH
15.30 14
12. Dehydroepiandrosterone Liver Neoplasms, Experimental M
9 genes: BCL2 | BCL2L1 | CYP1A2 | CYP2E1 | KRAS | MIRLET7D | NR1I3 | RB1 | TP53
14.02 11
13. Testosterone Hypertension M
67 genes: ABCC1 | ACE | ADIPOQ | ADRA2A | ADRB1 | AGT | AGTR1 | AGTR2 | AHR | ALB | AOC3 | AR | ATP1A2 | ATP2B1 | AVP | BCL2 | CAT | CAV1 | CCL2 | CD36 | COL1A1 | COL3A1 | CTGF | CYP1A1 | DUSP5 | ECE1 | EDN1 | EDNRA | EPO | F12 | FOS | GAL | GNRH1 | HIF1A | HMOX1 | HP | HSD11B1 | HSD11B2 | ICAM1 | IGF1 | INS | KCNJ1 | LEPR | LHB | MTOR | NCF1 | NOS2 | NOS3 | NPR1 | NR3C1 | POMC | PPARA | PPARG | PRKCD | PTEN | PTGS2 | RELA | RPS6KB1 | SCNN1A | SELP | SERPINE1 | SOD2 | TGFB1 | TGM2 | TNF | TP53 | UCN
13.91 223
14. Testosterone Atherosclerosis M
24 genes: ABCA1 | ADIPOQ | AGT | AHR | CCL2 | ESR1 | FASLG | GSTM1 | HP | ICAM1 | IFNG | IGF2 | IL6 | NOS2 | NOS3 | PPARG | PTGS2 | SERPINE1 | SOCS3 | SOD2 | TLR4 | TNF | TTPA | VEGFA
12.97 21
15. Dehydroepiandrosterone Liver Neoplasms M
9 genes: CDKN2A | CYP2E1 | ESR1 | JUN | KRAS | NAT2 | NR1I3 | PPARA | TP53
12.97 17
16. Testosterone Liver Neoplasms M
36 genes: ABL1 | AHR | ANXA2 | ATF3 | CDKN1B | CIDEA | CTNNB1 | CYP2E1 | EFNB2 | ESR1 | EXOSC2 | FST | GNMT | GPX3 | GSTM1 | HMOX1 | HRAS | IGF2 | IL12A | MAPK14 | MIR29A | MYC | MYO5B | NAT2 | NDRG1 | NR1H4 | NR1I3 | PPARA | PPARG | RAF1 | SCD | SERPINE1 | TNF | TNFSF10 | TP53 | TTC39A
12.95 41
17. Testosterone Propionate Prostatic Intraepithelial Neoplasia M
3 genes: AR | ESR1 | GSTP1
12.10 4
18. Testosterone Propionate Myocardial Infarction M
7 genes: AGT | CAT | ESR1 | IL1B | IL6 | REN | TNF
12.09 9
19. Testosterone Propionate Carcinoma, Hepatocellular M
7 genes: AR | CYP17A1 | ESR1 | GSTP1 | IGF1R | IL6 | TH
11.96 10
20. Testosterone Prostatic Intraepithelial Neoplasia M
7 genes: AR | CDKN1B | DNMT1 | ESR1 | ESR2 | PIM1 | PTEN
11.33 7
21. Testosterone Non-alcoholic Fatty Liver Disease M
13 genes: ACE | ADIPOQ | ATP5B | CD14 | CYP17A1 | CYP2E1 | FAS | GSTM1 | IL1A | PPARA | SREBF1 | STC2 | TGFB1
10.79 12
22. Testosterone Burns M
7 genes: IL1A | IL1B | IL6 | NOS2 | POMC | PTGS2 | TNF
10.73 5
23. Testosterone Status Epilepticus M
23 genes: ABCC2 | CASP3 | CASP8 | CAT | CCL2 | CRH | EPO | FOS | GDNF | HMOX1 | HSPB1 | JUNB | KCNK5 | NOS1 | NOS2 | NTRK2 | PTGS2 | SCN8A | SLC8A1 | SNTA1 | SRC | TNF | VEGFA
9.97 29
24. Testosterone Autism Spectrum Disorder M
11 genes: CNTNAP2 | DNMT3A | DNMT3B | GRIN2B | JARID2 | MTNR1B | NRXN1 | NRXN2 | NTSR1 | RAI1 | SOX9
9.51 13
25. Dehydroepiandrosterone Polycystic Ovary Syndrome M
5 genes: BAX | BCL2 | CYP19A1 | HSD3B1 | SRD5A1
9.36 6
26. Testosterone Parkinson Disease M
21 genes: BST1 | CP | CYP2E1 | DDC | DDIT4 | EDN1 | GDNF | GFAP | GSTM1 | HMOX1 | HSPA9 | IGF1R | IGF2 | IL6 | INS | INSR | NOS1 | RPL6 | SLC6A3 | SOD2 | TNF
8.55 22
Has associated exposure references.
27. Testosterone Propionate Insulin Resistance M
4 genes: AR | INS | INSR | TNF
8.53 8
28. Testosterone Fibrosis M
20 genes: ADRA2A | AGT | AKT1 | ALB | ATM | CCND2 | CHRNA1 | COL1A1 | COL3A1 | CYP19A1 | HMOX1 | IL1B | LEPR | MIR133A | NPR1 | PTGS2 | SOD2 | TGFB1 | THBS1 | TNF
8.20 25
29. Testosterone Kidney Neoplasms M
14 genes: AURKA | CCND1 | CDKN1B | CYP1A1 | EIF4EBP1 | IL32 | MAPK1 | MAPK3 | NDRG1 | PTGS2 | RAF1 | SOD2 | TNFSF10 | TSC2
8.14 11
30. Testosterone Pain M
11 genes: AKT1 | ALB | AVP | BDKRB1 | COMT | CRH | EDN1 | NTSR1 | PENK | POMC | TNF
8.03 16
31. Testosterone Propionate Hypertension M
7 genes: AGT | AR | CAT | INS | LHB | REN | TNF
7.47 84
32. Testosterone Propionate Adenocarcinoma M
4 genes: ESR1 | IL1B | PGR | TNF
7.15 6
33. Testosterone Aortic Aneurysm, Abdominal M
5 genes: AGT | AGTR1 | NCF1 | PTGS2 | SOD2
7.11 6
34. Androstenedione Alcoholism M
2 genes: FSHB | LHB
7.05 1
35. Dehydroepiandrosterone Sulfate Autistic Disorder M
3 genes: BCL2 | POMC | PRL
6.88 5
36. Testosterone Propionate Polycystic Ovary Syndrome M
3 genes: FSHR | INS | LHB
6.83 5
37. Fluticasone Anemia M
3 genes: CSF2 | IL2 | TNF
6.70 5
38. Testosterone Propionate Hyperinsulinism M
2 genes: INS | INSR
6.46 7
39. Methyltestosterone Carcinoma, Hepatocellular M
3 genes: AR | CYP1A1 | ESR1
6.26 6
40. Testosterone Nervous System Diseases M
24 genes: ABCC2 | ABCG2 | ACHE | ATF3 | CASP3 | CASP9 | CYP2C9 | FOS | FOXG1 | GFAP | MTHFR | NOS1 | NOTCH1 | PENK | PRODH | PTGS2 | SCN8A | SERPINE1 | SHMT1 | SLC6A3 | TNF | TRP53 | TTPA | TYMS
6.10 21
41. Methandrostenolone Carcinoma, Hepatocellular M
2 genes: AR | FST
5.88 4
42. Testosterone Leydig Cell Tumor M
3 genes: LHB | LHCGR | PRL
5.54 5
43. Testosterone Malaria M
7 genes: CD36 | CISH | HP | ICAM1 | NOS2 | SLC4A1 | TNF
5.20 4
44. Dehydroepiandrosterone Sulfate Hepatomegaly M
2 genes: NR1I2 | PPARA
5.10 3
45. Testosterone Prenatal Exposure Delayed Effects M
4 genes: ADORA1 | ATM | CTGF | MYOD1
5.03 8
46. testosterone enanthate Weight Gain M
7 genes: AKR1C2 | APP | CLIC4 | OSBPL8 | PALLD | PCYOX1 | PTRF
4.99 4
47. Loteprednol Etabonate Ocular Hypertension M   1 gene: NR3C1 4.88 2
48. Dehydroepiandrosterone Diabetes Mellitus, Type 1 M
2 genes: CAT | NOS3
4.85 3
49. Testosterone Cocaine-Related Disorders M
25 genes: BCHE | CAMK4 | CCKBR | COMT | CREB1 | CRH | EGR1 | EHMT2 | ESR2 | FOS | GAD1 | GDNF | GHRL | HOMER1 | MAPK1 | MAPK3 | MIR138-1 | MIR186 | MIR212 | MIR376C | NR3C1 | NTRK2 | POMC | PRL | SLC6A3
4.63 49
50. Testosterone Angina Pectoris M   1 gene: AVP 4.54 3
1–50 of 8,884 results.