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Chemical Anthramycin

Name Anthramycin
CAS Type 1 Name 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
Equivalent Terms Anthramycin, (11a alpha)-Isomer | Antramycin
CAS Registry Number 4803-27-4
Definition A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.
Structure Anthramycin
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D000876
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Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Benzazepines Has associated genes Has associated diseases Benzodiazepines Has associated genes Has associated diseases Benzodiazepinones Has associated genes Has associated diseases Anthramycin
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 3-Ring Has associated genes Has associated diseases Has associated exposure references Anthramycin

Top ↑ Descendants

Anthramycin
  1,11a-didehydroanhydroanthramycin
  (11R,11aS)-2-(N,N-dimethyl)acrylamide-1,10,11,11a-tetrahydro-11-methoxy-7,8-methylenedioxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one
  abbeymycin
  anthramycin 11-methyl ether
  anthramycin-DNA
  mazethramycin
  porothramycin A
  porothramycin B
  usabamycin A
  usabamycin B
  usabamycin C