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Chemical Benzazepines

1–50 of 400 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- histamine secretion mediated by immunoglobulin 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- results in increased histamine secretion mediated by immunoglobulin 1: Rattus norvegicus Hypothalamus, Posterior   1
2. 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- response to paraquat 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- results in decreased response to paraquat 1: Drosophila melanogaster Nervous System   1
3. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
4. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in increased abundance of 1-hydroxymethylmidazolam 1: Mus musculus Plasma 1 gene: CYP3A4 1
5. 1-hydroxymethylmidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
6. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
7. 1-hydroxymethylmidazolam drug metabolic process Rifampin [Rifampin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
8. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
9. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
10. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
11. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
12. 1-hydroxymethylmidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
13. 1-hydroxymethylmidazolam drug metabolic process Glycerol [Glycerol results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
14. 1-hydroxymethylmidazolam drug metabolic process Thalidomide [Thalidomide results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Placenta | Cell Line, Tumor 1 gene: CYP3A4 1
15. 1-hydroxymethylmidazolam drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: CYP3A4 | CYP3A5
1
16. 1-hydroxymethylmidazolam drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Hepatocytes | Cells, Cultured
2 genes: CYP3A4 | CYP3A5
1
17. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation LMO2 | TAL1 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide inhibits the reaction [[LMO2 protein co-treated with TAL1 protein] results in increased cell proliferation] 1: Mus musculus Blood | Cell Line, Tumor 1 gene: MYC 1
18. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation 1: Homo sapiens Blood | Tumor Cells, Cultured 1 gene: MYC 1
19. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
20. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation cyclopamine [cyclopamine co-treated with 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide] results in decreased cell proliferation 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
21. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation Quercetin Quercetin promotes the reaction [2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation] 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
22. 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide cell proliferation 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide results in decreased cell proliferation 1: Homo sapiens Blood | Cell Line, Tumor   1
23. 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide cell proliferation 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide results in decreased cell proliferation 1: Homo sapiens Jurkat Cells   1
24. 4'-chlorodiazepam cell chemotaxis 4'-chlorodiazepam results in increased cell chemotaxis 1: Homo sapiens Monocytes | Cells, Cultured   1
25. 4'-chlorodiazepam cell chemotaxis PK 11195 PK 11195 inhibits the reaction [4'-chlorodiazepam results in increased cell chemotaxis] 1: Homo sapiens Monocytes | Cells, Cultured   1
26. 4'-chlorodiazepam response to oxidative stress 4'-chlorodiazepam results in increased response to oxidative stress 1: Canis lupus familiaris Neutrophils | Cells, Cultured   1
27. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
28. 4-hydroxymidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
29. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
30. 4-hydroxymidazolam drug metabolic process Rifampin [Rifampin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
31. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
32. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
33. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
34. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
35. 4-hydroxymidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
36. 4-hydroxymidazolam drug metabolic process Glycerol [Glycerol results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
37. 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine chemical synaptic transmission 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine affects chemical synaptic transmission 1: Rattus norvegicus Prefrontal Cortex | Pyramidal Cells
3 genes: HRH1 | HTR2A | HTR2C
1
38. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation] 1: Mus musculus Spleen | T-Lymphocytes | Cells, Cultured   1
39. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins | IL2 IL2 protein inhibits the reaction [Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation]] 1: Homo sapiens Spleen | T-Lymphocytes | Cells, Cultured   1
40. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins | IL2RA IL2RA protein inhibits the reaction [Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation]] 1: Mus musculus Spleen | T-Lymphocytes | Cells, Cultured   1
41. Alprazolam regulation of blood pressure Alprazolam results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System   3
42. Alprazolam response to oxidative stress Caffeine [Caffeine co-treated with Alprazolam] results in increased response to oxidative stress 1: Homo sapiens HeLa Cells   1
43. Alprazolam response to oxidative stress Caffeine [Alprazolam co-treated with Caffeine] results in increased response to oxidative stress 1: Homo sapiens Myeloid Cells | Cell Line, Tumor   1
44. Alprazolam apoptotic process Alprazolam results in increased apoptotic process 1: Homo sapiens HeLa Cells
2 genes: CASP3 | PARP1
1
45. Alprazolam apoptotic process Caffeine Caffeine promotes the reaction [Alprazolam results in increased apoptotic process] 1: Homo sapiens HeLa Cells
2 genes: CASP3 | PARP1
1
46. Alprazolam apoptotic process Alprazolam results in increased apoptotic process 1: Homo sapiens Myeloid Cells | Cell Line, Tumor
2 genes: CASP3 | PARP1
1
47. Alprazolam apoptotic process Caffeine Caffeine promotes the reaction [Alprazolam results in increased apoptotic process] 1: Homo sapiens Myeloid Cells | Cell Line, Tumor
2 genes: CASP3 | PARP1
1
48. alsterpaullone apoptotic process Colchicine alsterpaullone inhibits the reaction [Colchicine results in increased apoptotic process] 1: Rattus norvegicus PC12 Cells
3 genes: CASP3 | LCK | TP53
1
49. alsterpaullone apoptotic process Cyclosporine alsterpaullone inhibits the reaction [Cyclosporine results in increased apoptotic process] 1: Rattus norvegicus Cerebellar Cortex | Neurons | Cells, Cultured
3 genes: CASP3 | LCK | TP53
1
50. alsterpaullone apoptotic process Tacrolimus alsterpaullone inhibits the reaction [Tacrolimus results in increased apoptotic process] 1: Rattus norvegicus Cerebellar Cortex | Neurons | Cells, Cultured
3 genes: CASP3 | LCK | TP53
1
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