| 1. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
positive regulation of mitochondrial depolarization
|
spermine nitric oxide complex
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [spermine nitric oxide complex results in increased positive regulation of mitochondrial depolarization] |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
|
1 |
| 2. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
cell death
|
benzyloxycarbonylleucyl-leucyl-leucine aldehyde
| linsidomine
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [linsidomine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cell death]] |
1: Rattus norvegicus |
PC12 Cells |
|
1 |
| 3. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
reactive nitrogen species metabolic process
|
Nitric Oxide
|
[1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole binds to Nitric Oxide] which results in increased reactive nitrogen species metabolic process |
|
|
|
1 |
| 4. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
apoptotic process
|
Benzo(a)pyrene
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole promotes the reaction [Benzo(a)pyrene results in increased apoptotic process] |
1: Rattus norvegicus |
Liver | Epithelial Cells | Cell Line |
3 genes: BCL2 | DDIT3 | TNFSF10
|
1 |
| 5. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
vasodilation
|
Mexiletine
| Nitroprusside
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [Mexiletine promotes the reaction [Nitroprusside results in increased vasodilation]] |
1: Rattus norvegicus |
Aorta |
|
1 |
| 6. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
protein modification process
|
Paraquat
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [Paraquat results in increased protein modification process] |
1: Homo sapiens |
Neurons | Cell Line, Tumor |
|
1 |
| 7. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
positive regulation of mitochondrial membrane permeability
|
spermine nitric oxide complex
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [spermine nitric oxide complex results in increased positive regulation of mitochondrial membrane permeability] |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
|
1 |
| 8. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
cell death
|
1-Methyl-4-phenylpyridinium
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cell death] |
1: Rattus norvegicus |
PC12 Cells |
|
2 |
| 9. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
cell death
|
sibutramine
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole promotes the reaction [sibutramine results in increased cell death] |
1: Homo sapiens |
Aorta | Endothelial Cells |
|
1 |
| 10. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
regulation of mitochondrial membrane potential
|
Benzo(a)pyrene
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [Benzo(a)pyrene affects regulation of mitochondrial membrane potential] |
1: Rattus norvegicus |
Liver | Epithelial Cells | Cell Line |
1 gene: BCL2
|
1 |
| 11. |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole
|
anoikis
|
|
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole results in increased anoikis |
1: Homo sapiens |
Lung | Cell Line, Tumor |
|
1 |
| 12. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide
|
cell proliferation
|
Cadmium
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide inhibits the reaction [Cadmium results in increased cell proliferation] |
1: Homo sapiens |
MCF-7 Cells |
4 genes: CD70 | CDK1 | FGF1 | NRG1
|
1 |
| 13. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide
|
regulation of nucleus size
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide affects regulation of nucleus size |
1: Homo sapiens |
Skin | Cell Line, Tumor |
|
1 |
| 14. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell death
|
nefazodone
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased cell death] |
1: Homo sapiens |
Hep G2 Cells |
|
1 |
| 15. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell proliferation
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in decreased cell proliferation |
1: Homo sapiens |
Neurons | Cell Line, Tumor |
6 genes: CTNNB1 | EGFR | MAP2K1 | MKI67 | RAF1 | STAT3
|
1 |
| 16. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell death
|
7-hydroxystaurosporine
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [7-hydroxystaurosporine results in increased cell death] |
1: Homo sapiens |
Breast | Cell Line, Tumor |
|
1 |
| 17. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate results in increased apoptotic process] |
|
Bone Marrow | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 18. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased apoptotic process |
1: Homo sapiens |
Schwann Cells | Cells, Cultured |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 19. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell cycle
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in decreased cell cycle |
1: Homo sapiens |
Neurons | Cell Line, Tumor |
6 genes: AHR | DDIT3 | MAPK1 | MAPK3 | MKI67 | RPS6KB1
|
1 |
| 20. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
MCL1
| sorafenib
|
MCL1 protein inhibits the reaction [[sorafenib co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in increased apoptotic process] |
1: Homo sapiens |
B-Lymphocytes | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 21. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
BCL2
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [BCL2 mutant form results in increased apoptotic process] |
|
Bone Marrow | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 22. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [arsenic trioxide results in increased apoptotic process] |
1: Homo sapiens |
Granulocyte Precursor Cells | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 23. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
| TP53AIP1
|
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [arsenic trioxide results in increased apoptotic process]] which results in increased expression of TP53AIP1 |
1: Homo sapiens |
Bone Marrow |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 24. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
positive regulation of ERK1 and ERK2 cascade
|
Plant Extracts
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Plant Extracts affects positive regulation of ERK1 and ERK2 cascade] |
1: Homo sapiens |
Hep G2 Cells |
4 genes: EGFR | IL6 | MAP2K1 | MAPK3
|
1 |
| 25. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
|
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased apoptotic process |
1: Rattus norvegicus |
Brain | Cells, Cultured |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 26. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased apoptotic process |
1: Homo sapiens |
Neurons | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 27. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell cycle
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in decreased cell cycle |
1: Homo sapiens |
Schwann Cells | Cell Line, Tumor |
6 genes: AHR | DDIT3 | MAPK1 | MAPK3 | MKI67 | RPS6KB1
|
1 |
| 28. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
| TP53AIP1
|
[[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with arsenic trioxide] results in increased apoptotic process] which results in increased expression of TP53AIP1 |
1: Homo sapiens |
Bone Marrow |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 29. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell proliferation
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in decreased cell proliferation |
1: Homo sapiens |
Schwann Cells | Cell Line, Tumor |
6 genes: CTNNB1 | EGFR | MAP2K1 | MKI67 | RAF1 | STAT3
|
1 |
| 30. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell death
|
7-hydroxystaurosporine
|
[7-hydroxystaurosporine co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in increased cell death |
1: Homo sapiens |
Cells |
|
1 |
| 31. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [arsenic trioxide results in increased apoptotic process] |
1: Homo sapiens |
K562 Cells |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 32. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell death
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased cell death |
1: Homo sapiens |
Breast | Cell Line, Tumor |
|
1 |
| 33. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
sorafenib
|
[sorafenib co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in increased apoptotic process |
1: Homo sapiens |
B-Lymphocytes | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 34. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell proliferation
|
ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate results in decreased cell proliferation] |
|
Bone Marrow | Cell Line, Tumor |
6 genes: CTNNB1 | EGFR | MAP2K1 | MKI67 | RAF1 | STAT3
|
1 |
| 35. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell death
|
7-hydroxystaurosporine
|
7-hydroxystaurosporine promotes the reaction [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased cell death] |
1: Homo sapiens |
Breast | Cell Line, Tumor |
|
1 |
| 36. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
positive regulation of ERK1 and ERK2 cascade
|
cypermethrin
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [cypermethrin results in increased positive regulation of ERK1 and ERK2 cascade] |
1: Mus musculus |
Gonadotrophs | Cell Line |
4 genes: EGFR | IL6 | MAP2K1 | MAPK3
|
1 |
| 37. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
Lovastatin
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [Lovastatin results in increased apoptotic process] |
1: Rattus norvegicus |
Brain | Cells, Cultured |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 38. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased apoptotic process |
1: Homo sapiens |
Schwann Cells | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 39. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
ATP biosynthetic process
|
leflunomide
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [leflunomide results in decreased ATP biosynthetic process] |
1: Homo sapiens |
Hep G2 Cells |
|
1 |
| 40. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
|
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide co-treated with arsenic trioxide] results in increased apoptotic process |
1: Homo sapiens |
Bone Marrow |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 41. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
arsenic trioxide
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [arsenic trioxide results in increased apoptotic process] |
1: Homo sapiens |
Bone Marrow |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 42. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
cell proliferation
|
7-hydroxystaurosporine
|
[7-hydroxystaurosporine co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in decreased cell proliferation |
1: Homo sapiens |
Cells |
6 genes: CTNNB1 | EGFR | MAP2K1 | MKI67 | RAF1 | STAT3
|
1 |
| 43. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
positive regulation of G1/S transition of mitotic cell cycle
|
Quercetin
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Quercetin results in decreased positive regulation of G1/S transition of mitotic cell cycle] |
1: Homo sapiens |
Myeloid Progenitor Cells | Cell Line, Tumor |
|
1 |
| 44. |
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
|
apoptotic process
|
BCL2
| ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
|
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [BCL2 inhibits the reaction [ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate results in increased apoptotic process]] |
|
Bone Marrow | Cell Line, Tumor |
12 genes: AHR | AIFM1 | CASP3 | CASP9 | DDIT3 | MAPK1 | MAPK3 | MCL1 | RAF1 | RPS6KB1 | TP53AIP1 | TP73
|
1 |
| 45. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of cyclic-nucleotide phosphodiesterase activity
|
|
2-(2-fluorobenzamido)benzoate ethyl ester results in decreased positive regulation of cyclic-nucleotide phosphodiesterase activity |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
| 46. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of cyclic-nucleotide phosphodiesterase activity
|
Cyclic AMP
|
[2-(2-fluorobenzamido)benzoate ethyl ester results in decreased positive regulation of cyclic-nucleotide phosphodiesterase activity] which results in increased abundance of Cyclic AMP |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
| 47. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of cyclic-nucleotide phosphodiesterase activity
|
N-Formylmethionine Leucyl-Phenylalanine
|
N-Formylmethionine Leucyl-Phenylalanine promotes the reaction [2-(2-fluorobenzamido)benzoate ethyl ester results in decreased positive regulation of cyclic-nucleotide phosphodiesterase activity] |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
| 48. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of reactive oxygen species biosynthetic process
|
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide
| N-Formylmethionine Leucyl-Phenylalanine
|
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2-(2-fluorobenzamido)benzoate ethyl ester inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased positive regulation of reactive oxygen species biosynthetic process]] |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
| 49. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of reactive oxygen species biosynthetic process
|
N-Formylmethionine Leucyl-Phenylalanine
|
2-(2-fluorobenzamido)benzoate ethyl ester inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased positive regulation of reactive oxygen species biosynthetic process] |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
| 50. |
2-(2-fluorobenzamido)benzoate ethyl ester
|
positive regulation of cyclic-nucleotide phosphodiesterase activity
|
Cyclic AMP
| N-Formylmethionine Leucyl-Phenylalanine
|
N-Formylmethionine Leucyl-Phenylalanine promotes the reaction [[2-(2-fluorobenzamido)benzoate ethyl ester results in decreased positive regulation of cyclic-nucleotide phosphodiesterase activity] which results in increased abundance of Cyclic AMP] |
1: Homo sapiens |
Neutrophils | Cells, Cultured |
|
1 |
Illuminating how chemicals affect human health.
Benzoates