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Chemical Benzopyrans

1–50 of 10,377 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-hydroxywarfarin xenobiotic glucuronidation 10-hydroxywarfarin results in decreased xenobiotic glucuronidation 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
2. 10-hydroxywarfarin xenobiotic glucuronidation Zidovudine [10-hydroxywarfarin results in decreased xenobiotic glucuronidation] which results in decreased glucuronidation of Zidovudine 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
3. 1',2'-dihydrorotenone apoptotic process 1',2'-dihydrorotenone results in increased apoptotic process 1: Homo sapiens Plasma Cells
6 genes: AKT1 | E2F1 | MAPK1 | MAPK3 | RB1 | TP53
1
4. 1',2'-dihydrorotenone cell proliferation 1',2'-dihydrorotenone results in decreased cell proliferation 1: Homo sapiens Plasma Cells | Cell Line, Tumor
3 genes: AKT1 | CDK4 | TP53
1
5. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells
2 genes: CDKN1A | TP53
1
6. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells | Cell Line, Tumor
2 genes: CDKN1A | TP53
1
7. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one cell proliferation tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in decreased cell proliferation] 1: Homo sapiens Retina | Neuroglia | Cell Line, Transformed
4 genes: BAX | BCL2 | NCF1 | TNF
1
8. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one apoptotic chromosome condensation Blood Glucose | Oxygen 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased apoptotic chromosome condensation] 1: Mus musculus Retinal Ganglion Cells   1
9. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of ERK1 and ERK2 cascade tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased positive regulation of ERK1 and ERK2 cascade] 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
7 genes: HMGB1 | ICAM1 | IL1B | IL6 | NOX4 | TLR4 | TNF
1
10. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of cell death 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one results in increased positive regulation of cell death 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
3 genes: HMGB1 | IL1B | PTGS2
1
11. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one reactive oxygen species biosynthetic process tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Retina | Neuroglia | Cell Line, Transformed 1 gene: NOX4 1
12. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one cellular response to light stimulus Blood Glucose | Oxygen 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased cellular response to light stimulus] 1: Mus musculus Retina   1
13. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of macrophage chemotaxis Blood Glucose | Oxygen 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased positive regulation of macrophage chemotaxis] 1: Rattus norvegicus Retina   1
14. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one superoxide dismutase activity tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in decreased superoxide dismutase activity] 1: Homo sapiens Retina | Neuroglia | Cell Line, Transformed   1
15. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of p38MAPK cascade tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased positive regulation of p38MAPK cascade] 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
2 genes: IL1B | NCF1
1
16. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of neuron apoptotic process Blood Glucose | Oxygen 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased positive regulation of neuron apoptotic process] 2: Mus musculus | Rattus norvegicus Retinal Ganglion Cells
4 genes: BAX | CASP3 | IL1B | TNF
1
17. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one apoptotic process tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased apoptotic process] 1: Homo sapiens Retina | Neuroglia | Cell Line, Transformed
7 genes: BAX | BCL2 | CASP3 | IL1B | NCF1 | PARP1 | TNF
1
18. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of I-kappaB kinase/NF-kappaB signaling tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
3 genes: IL1B | TLR4 | TNF
1
19. 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one positive regulation of apoptotic process tert-Butylhydroperoxide 1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased positive regulation of apoptotic process] 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
9 genes: BAX | CASP3 | HMGB1 | IL1B | IL6 | NOX4 | PTGS2 | TLR4 | TNF
1
20. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one response to oxidative stress gomesin 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [gomesin results in increased response to oxidative stress] 1: Homo sapiens Cell Line, Tumor
34 genes: ABCC2 | ABL1 | AIFM1 | AKT1 | APP | BCL2 | BCL2L1 | CAT | CHRNA4 | DAXX | DDIT3 | EGFR | EPAS1 | G6PD | GCLC | HMOX1 | KRT1 | MAP2K1 | MMP14 | MMP2 | MMP9 | NFKB1 | NQO1 | PCNA | PRNP | PTGS1 | PTGS2 | SOD1 | SOD2 | SOD3 | TLR4 | TP53 | TRP53 | UCN
1
21. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell migration Varenicline 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Varenicline results in increased cell migration] 1: Homo sapiens Human Umbilical Vein Endothelial Cells
25 genes: ARC | CDH2 | CDK1 | CDK5 | CTGF | ENG | FN1 | GSK3B | HBEGF | IL12A | IL12B | MMP14 | MMP2 | NOX1 | NRG1 | PDGFRB | PLCG1 | PRKCZ | PTEN | RPS6KB1 | SLC9A1 | SNAI1 | SRC | TGFB1 | VEGFA
1
22. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one lipid catabolic process Ethanol | Quercetin 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased lipid catabolic process]] 1: Homo sapiens Hepatocytes | Cells, Cultured
10 genes: MITF | PCK1 | PLA2G1B | PLA2G2A | PLA2G4A | PLA2G7 | PLCB1 | PLCB3 | PLCD1 | PLCG1
1
23. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell differentiation Capsaicin | Tretinoin 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin promotes the reaction [Tretinoin results in increased cell differentiation]] 1: Homo sapiens HL-60 Cells
35 genes: AKT1 | ANGPT1 | ARNT | BMP2 | CDH2 | CEBPA | CEBPB | CREB1 | CTGF | CTNNB1 | DSPP | EP300 | EPAS1 | FGF1 | FGF10 | FGF2 | FGF20 | FGF23 | FGF9 | GATA2 | GPER1 | GSK3B | HIF1A | MCL1 | MITF | NFATC4 | NGFR | RUNX2 | SLC9A1 | SPP1 | SQSTM1 | TFF1 | TNFSF11 | TP53 | VEGFA
1
24. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of apoptotic process arsenic trioxide 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arsenic trioxide results in increased positive regulation of apoptotic process] 1: Rattus norvegicus Heart Ventricles | Myocytes, Cardiac | Cell Line
73 genes: ABL1 | AIFM1 | AKT1 | ATM | BAD | BAX | BCL2L1 | BMP2 | CASP3 | CASP8 | CASP9 | CDK4 | CNR1 | CREB1 | CTNNB1 | CYP1B1 | CYR61 | DAXX | DDIT3 | DFFA | FAS | FASLG | FOSL1 | FOXO3 | GADD45A | GPER1 | GRIN1 | GRIN2A | GSK3B | HIF1A | HMOX1 | HPGD | IFNG | IL18 | IL1B | IL24 | IL6 | JUN | KNG1 | MAPK8 | MAPK9 | MIR21 | MMP2 | MMP9 | NFATC4 | NGF | NGFR | NOS2 | NOS3 | NR4A1 | PAWR | PDGFRB | PLA2G4A | PMAIP1 | POU4F1 | PPARG | PTEN | PTGS2 | RELA | RPS6 | S100B | SLC9A1 | SOD1 | SQSTM1 | SRC | TGFB1 | TGM2 | TLR3 | TLR4 | TNF | TP53 | TP73 | TRP53
1
25. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process Hydrogen Peroxide | LY 117018 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LY 117018 inhibits the reaction [Hydrogen Peroxide results in increased apoptotic process]] 1: Bos taurus Carotid Arteries | Endothelial Cells | Cells, Cultured
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
26. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of cell proliferation Atrazine 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Atrazine results in increased positive regulation of cell proliferation] 1: Homo sapiens Ovary | Cell Line, Tumor
94 genes: AGT | AKT1 | AR | AREG | ATF3 | BCL2 | BCL2L1 | BIRC5 | CCND1 | CCND3 | CD38 | CDK2 | CDK4 | CDKN1B | CRH | CSF2 | CTGF | CTNNB1 | CXCL10 | EDN1 | EDN2 | EDNRA | EDNRB | EGF | EGFR | EIF4G1 | FASLG | FGF1 | FGF10 | FGF2 | FGF20 | FGF5 | FGF7 | FGF9 | FN1 | FOSL1 | FSHB | GPER1 | GREM1 | HBEGF | HGF | HIF1A | HSF1 | IFNG | IGF1 | IL11 | IL18 | IL1B | IL2 | IL24 | IL6 | INS | JUN | KLF5 | KRAS | LEP | LIF | MAPK1 | MDM2 | MED1 | MIR21 | MYC | NCOR1 | NGF | NKX3-1 | NOX1 | NRG1 | NTF3 | OSM | PDGFA | PDGFB | PDGFRB | PGR | PLA2G1B | PLA2G4A | PLAU | PRKCZ | PRL | PTEN | PTGS2 | PTHLH | RELA | RUNX2 | S100B | ST8SIA1 | STAT1 | STAT3 | STS | TGFA | TGFB1 | THRB | TIMP1 | TNF | VEGFA
1
27. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one regulation of ERK1 and ERK2 cascade Glucose | sphingosine 1-phosphate 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] affects regulation of ERK1 and ERK2 cascade] 1: Rattus norvegicus Mesangial Cells | Cells, Cultured
6 genes: CYR61 | EGFR | FN1 | GSTP1 | IL1B | MAP2K1
1
28. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one superoxide dismutase activity Hydrogen Peroxide | PDK 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDK protein inhibits the reaction [Hydrogen Peroxide results in decreased superoxide dismutase activity]] 1: Rattus norvegicus PC12 Cells
4 genes: NQO1 | SOD1 | SOD2 | SOD3
1
29. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of apoptotic process arsenic trioxide 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [arsenic trioxide results in increased positive regulation of apoptotic process] 1: Homo sapiens Bronchioles | Epithelial Cells | Cell Line
73 genes: ABL1 | AIFM1 | AKT1 | ATM | BAD | BAX | BCL2L1 | BMP2 | CASP3 | CASP8 | CASP9 | CDK4 | CNR1 | CREB1 | CTNNB1 | CYP1B1 | CYR61 | DAXX | DDIT3 | DFFA | FAS | FASLG | FOSL1 | FOXO3 | GADD45A | GPER1 | GRIN1 | GRIN2A | GSK3B | HIF1A | HMOX1 | HPGD | IFNG | IL18 | IL1B | IL24 | IL6 | JUN | KNG1 | MAPK8 | MAPK9 | MIR21 | MMP2 | MMP9 | NFATC4 | NGF | NGFR | NOS2 | NOS3 | NR4A1 | PAWR | PDGFRB | PLA2G4A | PMAIP1 | POU4F1 | PPARG | PTEN | PTGS2 | RELA | RPS6 | S100B | SLC9A1 | SOD1 | SQSTM1 | SRC | TGFB1 | TGM2 | TLR3 | TLR4 | TNF | TP53 | TP73 | TRP53
1
30. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell proliferation illudin M 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [illudin M analog results in decreased cell proliferation] 1: Homo sapiens HCT116 Cells
47 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BCL2L1 | CD70 | CDC25C | CDK1 | CDK4 | CDK5 | CREBBP | CTNNB1 | CYP1A1 | CYR61 | EDNRA | EGFR | FGF1 | FGF2 | FGF5 | GH1 | GSK3B | HGF | IGF1 | IL12A | IL12B | IL18 | IL1A | MAP2K1 | MCM7 | MYC | NCF1 | NRG1 | OSM | PCNA | PRL | PTEN | S100B | SRC | STAT3 | TGFA | TGFB1 | TNF | TP53 | TYR | VEGFA
1
31. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell proliferation PQQ Cofactor | Rotenone 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PQQ Cofactor inhibits the reaction [Rotenone results in decreased cell proliferation]] 1: Homo sapiens Neurons | Cell Line, Tumor
47 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BCL2L1 | CD70 | CDC25C | CDK1 | CDK4 | CDK5 | CREBBP | CTNNB1 | CYP1A1 | CYR61 | EDNRA | EGFR | FGF1 | FGF2 | FGF5 | GH1 | GSK3B | HGF | IGF1 | IL12A | IL12B | IL18 | IL1A | MAP2K1 | MCM7 | MYC | NCF1 | NRG1 | OSM | PCNA | PRL | PTEN | S100B | SRC | STAT3 | TGFA | TGFB1 | TNF | TP53 | TYR | VEGFA
1
32. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process Cadmium Chloride | Tetradecanoylphorbol Acetate 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased apoptotic process]] 1: Homo sapiens U937 Cells
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
33. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell aging Busulfan | SB 203580 [SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Busulfan results in increased cell aging] 1: Homo sapiens Fibroblasts | Cell Line
8 genes: BCL2 | BGLAP | CDK1 | ICAM1 | MIR22 | SOD1 | TP53 | TRP53
1
34. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell proliferation IL2 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IL2 protein results in increased cell proliferation] T-Lymphocytes | Cell Line
47 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BCL2L1 | CD70 | CDC25C | CDK1 | CDK4 | CDK5 | CREBBP | CTNNB1 | CYP1A1 | CYR61 | EDNRA | EGFR | FGF1 | FGF2 | FGF5 | GH1 | GSK3B | HGF | IGF1 | IL12A | IL12B | IL18 | IL1A | MAP2K1 | MCM7 | MYC | NCF1 | NRG1 | OSM | PCNA | PRL | PTEN | S100B | SRC | STAT3 | TGFA | TGFB1 | TNF | TP53 | TYR | VEGFA
1
35. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of cell death Acetaminophen | Chlorogenic Acid 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased positive regulation of cell death]] 1: Homo sapiens Liver | Hepatocytes | Cell Line
18 genes: AIFM1 | CD36 | CDKN1A | CDKN1B | CRH | CTGF | EGR1 | EIF4G1 | EP300 | FAS | GRIN1 | GRIN2A | GRIN2B | IL1B | NKX3-1 | PRNP | PTGS2 | UCP2
1
36. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of ERK1 and ERK2 cascade xestospongin C 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [xestospongin C affects positive regulation of ERK1 and ERK2 cascade] 1: Homo sapiens HL-60 Cells
39 genes: ABL1 | ANGPT1 | APP | BMP2 | CD36 | CHI3L1 | CTGF | EDNRA | EGFR | ESR1 | FGF10 | FGF2 | FGF20 | FGF23 | GATA4 | GPER1 | ICAM1 | IL1A | IL1B | IL6 | ITGB3 | JUN | MAP2K1 | MAPK3 | MIR21 | PDGFA | PDGFB | PDGFRB | PLA2G2A | PRKCA | PRKCZ | PTEN | SRC | TGFB1 | TLR2 | TLR4 | TNF | TRPV4 | VEGFA
1
37. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased apoptotic process 1: Rattus norvegicus Heart | Cell Line
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
38. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic DNA fragmentation withaferin A 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [withaferin A results in increased apoptotic DNA fragmentation] 1: Homo sapiens MCF-7 Cells
2 genes: CASP3 | DFFA
1
39. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of cell proliferation Aflatoxin B1 | Zearalenone [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased susceptibility to [Zearalenone co-treated with Aflatoxin B1]] which results in increased positive regulation of cell proliferation 1: Homo sapiens MCF-7 Cells
94 genes: AGT | AKT1 | AR | AREG | ATF3 | BCL2 | BCL2L1 | BIRC5 | CCND1 | CCND3 | CD38 | CDK2 | CDK4 | CDKN1B | CRH | CSF2 | CTGF | CTNNB1 | CXCL10 | EDN1 | EDN2 | EDNRA | EDNRB | EGF | EGFR | EIF4G1 | FASLG | FGF1 | FGF10 | FGF2 | FGF20 | FGF5 | FGF7 | FGF9 | FN1 | FOSL1 | FSHB | GPER1 | GREM1 | HBEGF | HGF | HIF1A | HSF1 | IFNG | IGF1 | IL11 | IL18 | IL1B | IL2 | IL24 | IL6 | INS | JUN | KLF5 | KRAS | LEP | LIF | MAPK1 | MDM2 | MED1 | MIR21 | MYC | NCOR1 | NGF | NKX3-1 | NOX1 | NRG1 | NTF3 | OSM | PDGFA | PDGFB | PDGFRB | PGR | PLA2G1B | PLA2G4A | PLAU | PRKCZ | PRL | PTEN | PTGS2 | PTHLH | RELA | RUNX2 | S100B | ST8SIA1 | STAT1 | STAT3 | STS | TGFA | TGFB1 | THRB | TIMP1 | TNF | VEGFA
1
40. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell proliferation Estradiol | IGF1 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein promotes the reaction [Estradiol results in increased cell proliferation]] 1: Homo sapiens MCF-7 Cells
47 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BCL2L1 | CD70 | CDC25C | CDK1 | CDK4 | CDK5 | CREBBP | CTNNB1 | CYP1A1 | CYR61 | EDNRA | EGFR | FGF1 | FGF2 | FGF5 | GH1 | GSK3B | HGF | IGF1 | IL12A | IL12B | IL18 | IL1A | MAP2K1 | MCM7 | MYC | NCF1 | NRG1 | OSM | PCNA | PRL | PTEN | S100B | SRC | STAT3 | TGFA | TGFB1 | TNF | TP53 | TYR | VEGFA
1
41. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of cell cycle arrest 4-phenylenediamine 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [4-phenylenediamine results in increased positive regulation of cell cycle arrest] 1: Homo sapiens Liver | Cell Line
6 genes: BRCA1 | POU4F1 | TGFB1 | TP53 | TP73 | TRP53
1
42. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one lipid catabolic process Ethanol | Quercetin | SB 203580 [SB 203580 co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased lipid catabolic process]] 1: Homo sapiens Hepatocytes | Cells, Cultured
10 genes: MITF | PCK1 | PLA2G1B | PLA2G2A | PLA2G4A | PLA2G7 | PLCB1 | PLCB3 | PLCD1 | PLCG1
1
43. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process 8-bromocyclic GMP | EDN1 | MAP2K1 [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [EDN1 protein inhibits the reaction [8-bromocyclic GMP results in increased apoptotic process]] Myocytes, Cardiac | Cells, Cultured
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
44. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one wound healing, spreading of cells Luteolin 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Luteolin results in decreased wound healing, spreading of cells] 1: Homo sapiens Lung | Cell Line, Tumor 1 gene: CYR61 1
45. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process gemcitabine 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [gemcitabine results in increased apoptotic process] 1: Homo sapiens Lung | Cell Line, Tumor
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
46. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of ERK1 and ERK2 cascade sodium arsenite 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased positive regulation of ERK1 and ERK2 cascade] 1: Homo sapiens Lung | Cell Line, Tumor
39 genes: ABL1 | ANGPT1 | APP | BMP2 | CD36 | CHI3L1 | CTGF | EDNRA | EGFR | ESR1 | FGF10 | FGF2 | FGF20 | FGF23 | GATA4 | GPER1 | ICAM1 | IL1A | IL1B | IL6 | ITGB3 | JUN | MAP2K1 | MAPK3 | MIR21 | PDGFA | PDGFB | PDGFRB | PLA2G2A | PRKCA | PRKCZ | PTEN | SRC | TGFB1 | TLR2 | TLR4 | TNF | TRPV4 | VEGFA
1
47. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process ciglitazone 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ciglitazone results in increased apoptotic process] Osteoblasts
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
48. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one apoptotic process arsenic trioxide 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [arsenic trioxide results in increased apoptotic process] 1: Homo sapiens K562 Cells
74 genes: ABL1 | AHR | AIFM1 | AKT1 | APP | ATG5 | ATM | BAD | BAX | BCL2 | BCL2L1 | BECN1 | BIRC5 | BRCA1 | CASP3 | CASP7 | CASP8 | CASP9 | CD14 | CDK1 | CDK5 | CGB3 | CHEK2 | CHI3L1 | DAXX | DDIT3 | DFFA | EP300 | FAS | FASLG | FOXO3 | GADD45A | GJA1 | GPER1 | GREM1 | HCAR2 | HMOX1 | IFNG | IL17A | IL1A | IL1B | IL24 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | NCF1 | NFKB1 | NFKBIA | NGFR | NR3C1 | NR4A1 | PARP1 | PAWR | PCSK9 | PMAIP1 | PRF1 | PRKCA | PTEN | RB1 | RPS6KA3 | RPS6KB1 | SQSTM1 | TF | TLR2 | TNF | TNFRSF10A | TNFRSF10B | TNFRSF11B | TP53 | TP53AIP1 | TP73 | TRP53
1
49. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cell proliferation Tetrachlorodibenzodioxin 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased cell proliferation] 1: Homo sapiens Fetus | Palate | Cells, Cultured
47 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BCL2L1 | CD70 | CDC25C | CDK1 | CDK4 | CDK5 | CREBBP | CTNNB1 | CYP1A1 | CYR61 | EDNRA | EGFR | FGF1 | FGF2 | FGF5 | GH1 | GSK3B | HGF | IGF1 | IL12A | IL12B | IL18 | IL1A | MAP2K1 | MCM7 | MYC | NCF1 | NRG1 | OSM | PCNA | PRL | PTEN | S100B | SRC | STAT3 | TGFA | TGFB1 | TNF | TP53 | TYR | VEGFA
1
50. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one positive regulation of reactive oxygen species biosynthetic process 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased positive regulation of reactive oxygen species biosynthetic process 1: Rattus norvegicus Aorta | Tunica Media
5 genes: CD36 | FOXO3 | GRIN1 | TLR4 | TLR6
1
1–50 of 10,377 results.