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Chemical Buprenorphine

Name Buprenorphine
CAS Type 1 Name 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
Equivalent Terms 6029M | 6029 M | 6029-M | Buprenex | Buprenorphine Grünenthal Brand | Buprenorphine Hydrochloride | Buprex | Essex Brand of Buprenorphine Hydrochloride | Grünenthal Brand of Buprenorphine | Grünenthal Brand of Buprenorphine Hydrochloride | Hydrochloride, Buprenorphine | Key Brand of Buprenorphine Hydrochloride | Prefin | Reckitt Benckiser Brand of Buprenorphine Hydrochloride | Reckitt Brand of Buprenorphine Hydrochloride | Reckitt & Colman Brand 1 of Buprenorphine Hydrochloride | Reckitt & Colman Brand 2 of Buprenorphine Hydrochloride | RX6029M | RX 6029 M | RX-6029-M | Schering Plough Brand of Buprenorphine Hydrochloride | Schering-Plough Brand of Buprenorphine Hydrochloride | Subutex | Temgesic | Temgésic
CAS Registry Number 52485-79-7
Definition A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Structure Buprenorphine
Top Interacting
Genes
MeSH® ID D002047
External Links

Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated exposure references Opiate Alkaloids Has associated genes Has associated diseases Morphinans Has associated genes Has associated diseases Buprenorphine Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds with 4 or More Rings Has associated genes Has associated diseases Has associated exposure references Morphinans Has associated genes Has associated diseases Buprenorphine Has associated genes Has associated diseases
3. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Bridged-Ring Has associated genes Has associated diseases Morphinans Has associated genes Has associated diseases Buprenorphine Has associated genes Has associated diseases
4. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Polycyclic Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Phenanthrenes Has associated genes Has associated diseases Has associated exposure references Morphinans Has associated genes Has associated diseases Buprenorphine Has associated genes Has associated diseases

Top ↑ Descendants

Buprenorphine Has associated genes Has associated diseases
  2-(N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl)-3,3-dimethylpentan-2-ol
  6-O-(2-fluoroethyl)buprenorphine
  BU08070
  BU08073
  BU 48
  buprenorphine-3-O-glucuronide
  Buprenorphine, Naloxone Drug Combination Has associated diseases
  demethoxybuprenorphine
  HS 599
  N-(3-fluoropropyl)-N-norbuprenorphine
  norbuprenorphine Has associated genes Has associated diseases
  norbuprenorphine-3-beta-D-glucuronide
  thenorphine
  thienorphine