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Chemical Calcitriol

These diseases are associated with Calcitriol or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 2,817 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. seocalcitol Hypercalcemia M
4 genes: CYP24A1 | CYP27B1 | PTH | PTHLH
15.15 13
2. calcipotriene Dermatitis, Atopic M
3 genes: FLG | MAPK8 | TSLP
13.01 8
3. 1,25-dihydroxy-16-ene-vitamin D3 Hypercalcemia M
2 genes: CYP24A1 | PTH
10.60 10
4. Calcitriol Calcinosis M
11 genes: BGLAP | CASP3 | CCL2 | COL1A1 | FGF23 | IL1B | LCN2 | LSP1 | MMP2 | MMP9 | SPP1
10.20 6
5. Calcitriol Infertility, Female M
12 genes: AR | CEBPA | CEBPB | CYP19A1 | ESR1 | LEP | MAPK1 | MAPK3 | MTHFR | NR1I2 | PAPPA | TP53
9.98 8
6. Calcitriol Poisoning M
3 genes: ABCB1 | BCHE | CDKN2B
9.59 7
7. seocalcitol Hypercalciuria M
2 genes: CYP24A1 | PTH
9.32 4
8. maxacalcitol Hypercalcemia M
2 genes: CYP24A1 | PTH
8.81 11
9. Calcitriol Hypertension M
58 genes: ABCC1 | ADIPOQ | AGTR1B | AOC3 | AR | ATP1A1 | ATP1A2 | ATP2B1 | BCL2 | CAV1 | CCL2 | COL1A1 | COL3A1 | CRP | CXCL2 | CYP1A1 | DUSP5 | EDN1 | ELN | FOS | GAL | GCLC | GJA4 | GUCY1A3 | HMOX1 | HSD11B1 | HSD11B2 | IER3 | IGF1 | INS | KCNJ1 | LEP | LPL | LTF | MCPT1 | MMP2 | NOS2 | NOS3 | OLR1 | PPARA | PPARG | PTGS2 | PTH | RELA | REN | SCNN1A | SCNN1B | SOD2 | SOD3 | STK39 | TGFB1 | TGM2 | TNF | TP53 | UCP2 | VAV3 | VDR | VWF
6.46 100
10. Calcitriol Bone Diseases, Metabolic M
6 genes: CYP27A1 | DHCR7 | ESR1 | GC | IGF1 | MMP2
5.89 5
11. maxacalcitol Hyperphosphatemia M   1 gene: PTH 5.58 2
12. Ro 23-7553 Hypercalcemia M   1 gene: PTH 5.10 8
13. Calcitriol Drug Eruptions M
4 genes: ALOX5 | CYP1A1 | IL4 | MTHFR
4.60 4
14. calcipotriene Hypercalcemia M   1 gene: CYP24A1 4.50 6
15. Calcitriol Hypertrophy, Left Ventricular M
9 genes: ACTA1 | COL1A1 | COL3A1 | EDN1 | GDF15 | HBEGF | MYC | PPP3CA | REN
3.96 10
16. Calcitriol Hyperphosphatemia M
2 genes: FGF23 | PTH
3.89 9
17. Calcitriol AORTIC VALVE DISEASE 1 M   1 gene: MGP 3.79 2
18. Calcitriol Nephrocalcinosis M   1 gene: PHEX 3.48 6
19. Calcitriol Uterine Diseases M   1 gene: CGA 3.35 2
20. Calcitriol Hypercalciuria M
2 genes: CYP24A1 | PTH
3.22 12
21. Calcitriol Nephrolithiasis M   1 gene: CYP24A1 3.20 2
22. Calcitriol Myoglobinuria M   1 gene: LDHA 3.11 2
23. Calcitriol Weight Loss M
9 genes: ADIPOQ | ATG5 | IFNA2 | IL10 | IL4 | INS | LTF | MAPT | TSC22D3
3.01 9
24. Calcitriol Ovarian Diseases M
2 genes: CGA | CYP19A1
2.99 3
25. Calcitriol Kidney Calculi M   1 gene: SPP1 2.96 3
26. Calcitriol Aneurysm M   1 gene: MMP1 2.93 2
27. Calcitriol Aortic Diseases M
3 genes: MMP2 | MMP9 | SOD2
2.85 3
28. Calcitriol Gout M
2 genes: CD14 | IL1B
2.70 2
29. Calcitriol Lymphoma, Non-Hodgkin M
6 genes: BCL2 | CHEK2 | IFNA2 | MTHFR | RAD54L | TYMS
1.91 8
30. Calcitriol Alkalosis M     1
31. Calcitriol Angioedema M     1
32. 1,25-(dihydroxy-21-(3-hydorxy-3-methyl-butyl)-nor-cholecalciferol) Hypercalcemia M     1
33. calcipotriene Hypernatremia M     1
34. maxacalcitol Kidney Failure, Chronic M     1
35. Calcitriol Mood Disorders M     1
36. Ro 23-7553 Nephrocalcinosis M     1
37. Calcitriol Parathyroid Diseases M     1
38. seocalcitol Weight Loss M     1
39. Calcitriol Renal Insufficiency M T
5 genes: CYP24A1 | EDN1 | IFNA2 | IFNG | INS
5.96 12
40. Calcitriol Hypercalcemia M T
9 genes: CASR | CYP24A1 | CYP27B1 | IL6 | PTH | PTHLH | TNF | TNFRSF11B | TNFSF11
4.10 58
41. Calcitriol Osteomalacia M T   1 gene: MEPE 4.08 3
42. Calcitriol Hypocalcemia M T
2 genes: CASR | PTH
3.25 5
43. Calcitriol Renal Osteodystrophy M T     6
44. Calcitriol Prostatic Neoplasms T
175 genes: ABCC4 | ADRB2 | AGR2 | AKT1 | AMACR | ANXA3 | AR | ATF3 | ATM | AURKA | AZGP1 | B2M | BAX | BAZ2A | BCAS1 | BCL2 | BGLAP | BMP7 | BMPR1B | BRCA1 | BRCA2 | CASP9 | CAV1 | CCND1 | CCND2 | CD82 | CDH1 | CDKN1A | CDKN1B | CHEK2 | CLDN3 | CLDN7 | CLU | CREBBP | CRYAB | CST6 | CTNNB1 | CTSB | CXCL8 | CYP19A1 | CYP1A1 | CYP2A6 | CYP3A4 | CYP3A5 | CYP7B1 | DAB2IP | DDR1 | DEFB1 | DNAJC3 | DNMT1 | DNMT3B | EAF2 | EFEMP2 | EGF | EGFR | EGR1 | EHBP1 | EHF | EMP1 | EMP3 | ERBB3 | ESR1 | EZH2 | FASLG | FBLN1 | FOLH1 | FOXC1 | GADD45A | GCNT1 | GDF15 | GHR | GNMT | GRB7 | GREB1 | GSTM1 | HIST1H4H | HPGD | HPN | HSD3B1 | IGF1 | IGFBP3 | IL10 | IL16 | IL1RN | IL2 | IL24 | IL6 | INADL | INS | IRS1 | ITPR1 | JUP | KLK2 | KLK3 | KLK5 | LEP | LIFR | LPAR1 | LPL | LZTS1 | MAPK3 | MMP13 | MMP9 | MSR1 | MTHFR | MYC | MYCL | MYH14 | NAT1 | NAT2 | NCOA1 | NCOA2 | NCOA3 | NGFR | NOS3 | NRP1 | NUCB2 | P4HB | PAK6 | PDZK1IP1 | PIK3CA | PKP3 | PLAUR | PODXL | PPARA | PPFIBP2 | PPP3CA | PRNP | PSMC3IP | PTGS2 | PTHLH | RAB4B | RASD1 | RLN2 | RNASEL | RPS19 | RRAS | RUNX1 | RXRA | SEPP1 | SERPINA3 | SERPINF1 | SLC39A1 | SLC7A1 | SOD2 | SPON2 | SSX2 | ST14 | STAT3 | STEAP4 | STMN1 | SULT2B1 | TBXAS1 | TERT | TGFA | TGFB1 | TGFBR2 | TJP3 | TMOD1 | TMPRSS2 | TNFRSF21 | TOP2A | TP53 | TPBG | TPD52 | TPD52L1 | TRAF1 | TYMS | UCK2 | UGT2B15 | UGT2B17 | VAV3 | VDR | VEGFA | VIM
184.51 188
Has associated exposure references.
45. Calcitriol Breast Neoplasms T
165 genes: ABCB1 | ABCC1 | ABL1 | ACTA2 | AGR2 | AKAP12 | AKT1 | APOBEC3B | AR | AREG | ARRDC3 | ATM | AURKA | BAG1 | BARD1 | BAX | BCHE | BCL2 | BCL2A1 | BIRC2 | BIRC5 | BMP2 | BMP4 | BRCA1 | BRCA2 | BRIP1 | C10ORF10 | CASP8 | CAV1 | CCL20 | CCND1 | CD40 | CDA | CDH1 | CDKN1B | CENPF | CHEK2 | CLDN1 | CLDN4 | CSF1 | CSF1R | CST6 | CTNNB1 | CXCL2 | CXCL3 | CXCL8 | CYP19A1 | CYP1A1 | CYP3A4 | DDIT3 | DNMT1 | DNMT3B | DSC3 | E2F1 | EDNRB | EEF2 | EFNA1 | EGF | EGFR | EIF2S2 | EP300 | EPB41L3 | ERBB3 | ESR1 | ETS2 | EXO1 | EZH2 | FASN | FGFR1 | FGFR2 | FHL2 | FLT1 | FOS | FOXM1 | FOXP3 | FST | GPX2 | GRB7 | H2AFX | HES1 | HMMR | HMOX1 | IFNG | IGF1 | IGF1R | IGFBP5 | IL1B | IL24 | IL6 | ITSN2 | JAG2 | JUN | KDR | KIT | KLK10 | KRT18 | KRT5 | LEP | LIMD2 | LPAR1 | LSP1 | MAP3K1 | MECOM | MIR29A | MKI67 | MMP1 | MMP2 | MMP3 | MMP9 | MTHFR | NAT2 | NCOA1 | NCOA2 | NCOA3 | NCOR1 | NFKBIA | NOS2 | NOS3 | NR2F1 | NRIP1 | OCLN | PAEP | PDE2A | PHB | PIK3CA | PRC1 | PTGS1 | PTGS2 | PTHLH | PTPRD | RAD51 | RAD51C | RAD54L | RB1 | RELA | RRAD | SERPINB2 | SERPINB5 | SLC22A18 | SLC2A2 | SLC2A5 | SLC39A6 | SNAI2 | SNCG | SOD2 | SPP1 | STAT3 | STAT5A | STC2 | STMN1 | SYNJ2 | TERT | TFAP2A | TGM2 | TNF | TOP2A | TOX3 | TP53 | TYMS | UBE2C | VDR | VIM | WHSC1 | XRCC2 | XRCC3
138.73 195
46. Calcitriol Colorectal Neoplasms T
78 genes: ABCA1 | ABCA12 | ABCA3 | ABCB1 | ABCB10 | ABCB4 | ABCB5 | ABCC1 | ABCC2 | ABCC3 | ABCC4 | ABCD3 | ACKR3 | AKT1 | AMACR | AURKA | BCL2 | BIRC5 | BMP4 | BUB1B | CASP8 | CCND1 | CDH1 | CHEK2 | CTNNB1 | CXCL8 | CYP2A6 | EGFR | EP300 | EPHA1 | EXO1 | FADS1 | FEN1 | FGFR3 | FLNC | GGH | GREM1 | GSTM1 | IFNA2 | IGFBP3 | IL6ST | KDR | LY96 | MKI67 | MMP1 | MMP2 | MTHFR | NAMPT | NME2 | ODC1 | PDGFRL | PIK3CA | POLD1 | PPARG | PRKD1 | PTGS2 | PTPRD | RET | RHPN2 | RNF43 | RRM2 | SEPP1 | SERPINB5 | SFRP4 | SH3TC1 | SMAD7 | SOD2 | SPARC | TGFB1 | TK1 | TNF | TNFSF13 | TP53 | TP63 | TXNRD1 | TYMP | TYMS | UNG
81.82 77
47. Calcitriol Lung Neoplasms T
76 genes: ACTB | AKT1 | AZGP1 | BCL2L1 | BECN1 | BIRC5 | BRCA2 | CASP8 | CCND1 | CDKN1A | CDKN1B | CEACAM1 | CHEK2 | CRP | CTNNB1 | CXCL14 | CYP24A1 | CYP2A6 | DAB2IP | DAPK1 | DDR1 | EAF2 | EEF2 | EGFR | ERBB3 | ESR1 | FAS | FGFR1 | FGFR2 | FOS | FOXM1 | GC | GRB7 | GSTM1 | HES1 | HMOX1 | IFNG | IL10 | IL1B | IL2 | IL24 | IL6 | IRF1 | JUN | JUNB | MAP3K8 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MMP1 | MTHFR | MYC | NOS2 | PCNA | PIK3CA | PRDX6 | PTGIS | PTGS2 | SEPP1 | SERPINA1 | SFTPB | SLC22A18 | SLCO1B3 | SPP1 | SPRY2 | STAT5A | TERT | TGFB1 | TGFBR2 | TNF | TP53 | TP63 | TYMS | UGT2B17 | WNT5A
50.55 92
48. Calcitriol Carcinoma, Squamous Cell T
37 genes: AKT1 | ANXA2 | APOBEC3B | AREG | ATM | CCL2 | CDH1 | CEBPA | CRYAB | CXCL8 | EGFR | FGFR1 | GSTM1 | HCAR3 | IFNA2 | IL6 | IVL | KNSTRN | KRT10 | KRT6B | MAPK1 | MAPK3 | MMP9 | NCOA3 | PIK3CA | PTGS2 | SERPINB3 | SFN | SLC45A2 | SOD2 | SPRR1A | STAT3 | TGFB1 | TP53 | TP63 | TYMS | VEGFA
31.76 33
49. Calcitriol Leukemia, Myeloid, Acute T
36 genes: ADCY7 | ANXA2 | ATP1B1 | BCL2 | CAPG | CAPN2 | CD44 | CEBPA | CEBPD | CHIC2 | CSF1R | CTNNA1 | DAPK1 | FAS | FHL2 | FOXO1 | GATA2 | ID2 | KIT | LPAR1 | LPP | MLF1 | MN1 | MYC | NPM1 | PDE4B | RUNX1 | RUNX1T1 | S100A10 | S100A8 | SGK1 | SPARC | STAT3 | SYNGR1 | TCEA2 | VSIG4
26.28 19
50. Calcitriol Pancreatic Neoplasms T
33 genes: ATM | BCL2L1 | BRCA1 | BRCA2 | CD44 | CDH1 | CTNNB1 | CXCL8 | FXYD3 | GADD45A | IFNA2 | IL24 | KDR | KLF5 | MMP9 | MYC | NFKBIA | NRP1 | PALLD | PPARG | PTGS2 | PTHLH | RB1 | SLC29A1 | SOD2 | STAT3 | TERT | TGFB1 | TNF | TP53 | TP63 | TYMP | TYMS
24.90 37
1–50 of 2,817 results.