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Chemical Camptothecin

1–50 of 450 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-hydroxycamptothecin apoptotic process Fluorouracil | Leucovorin [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased apoptotic process 1: Homo sapiens Intestine, Large | Cells
4 genes: BCL2 | BCL2L1 | CASP3 | DDIT3 		1
2. 10-hydroxycamptothecin cell proliferation 10-hydroxycamptothecin results in decreased cell proliferation 1: Homo sapiens Ovary | Cell Line, Tumor
2 genes: BCL2 | BCL2L1 		1
3. 10-hydroxycamptothecin apoptotic process 10-hydroxycamptothecin results in increased apoptotic process 1: Homo sapiens Ovary | Cell Line, Tumor
4 genes: BCL2 | BCL2L1 | CASP3 | DDIT3 		1
4. 10-hydroxycamptothecin apoptotic DNA fragmentation 10-hydroxycamptothecin results in increased apoptotic DNA fragmentation 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: CASP3 1
5. 10-hydroxycamptothecin cell proliferation 10-hydroxycamptothecin results in decreased cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: BCL2 | BCL2L1 		1
6. 10-hydroxycamptothecin cell proliferation 10-hydroxycamptothecin analog affects cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: BCL2 | BCL2L1 		1
7. 10-hydroxycamptothecin mitotic cell cycle arrest 10-hydroxycamptothecin results in increased mitotic cell cycle arrest 1: Homo sapiens Lung | Cell Line, Tumor   1
8. 10-hydroxycamptothecin mitotic cell cycle arrest 10-hydroxycamptothecin analog results in increased mitotic cell cycle arrest 1: Homo sapiens Lung | Cell Line, Tumor   1
9. 10-hydroxycamptothecin apoptotic process 10-hydroxycamptothecin results in increased apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor
4 genes: BCL2 | BCL2L1 | CASP3 | DDIT3 		1
10. 10-hydroxycamptothecin apoptotic process 10-hydroxycamptothecin analog results in increased apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor
4 genes: BCL2 | BCL2L1 | CASP3 | DDIT3 		1
11. 10-hydroxycamptothecin cell proliferation Roscovitine Roscovitine promotes the reaction [10-hydroxycamptothecin analog affects cell proliferation] 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: BCL2 | BCL2L1 		1
12. 10-hydroxycamptothecin cell proliferation olomoucine olomoucine promotes the reaction [10-hydroxycamptothecin analog affects cell proliferation] 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: BCL2 | BCL2L1 		1
13. 10-hydroxycamptothecin negative regulation of cell proliferation 10-hydroxycamptothecin results in increased negative regulation of cell proliferation 1: Homo sapiens Stomach | Cell Line, Tumor 1 gene: BCL2 1
14. 7-ethyl-10-hydroxycamptothecin glucuronide drug metabolic process Paclitaxel [Paclitaxel results in increased drug metabolic process] which results in increased abundance of 7-ethyl-10-hydroxycamptothecin glucuronide 1: Mus musculus Hepatocytes | Cells, Cultured   1
15. 7-ethyl-10-hydroxycamptothecin glucuronide drug metabolic process Paclitaxel | TLR4 TLR4 protein mutant form inhibits the reaction [[Paclitaxel results in increased drug metabolic process] which results in increased abundance of 7-ethyl-10-hydroxycamptothecin glucuronide] 1: Mus musculus Hepatocytes | Cells, Cultured   1
16. 7-ethyl-14-aminocamptothecin cell proliferation 7-ethyl-14-aminocamptothecin results in decreased cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor   1
17. 7-ethyl-14-aminocamptothecin cell proliferation 7-ethyl-14-aminocamptothecin results in decreased cell proliferation 1: Homo sapiens HT29 Cells   1
18. 7-ethyl-14-aminocamptothecin cell proliferation 7-ethyl-14-aminocamptothecin results in decreased cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor   1
19. 9-aminocamptothecin cell proliferation 9-aminocamptothecin results in decreased cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor   1
20. 9-aminocamptothecin mitotic cell cycle arrest 9-aminocamptothecin results in increased mitotic cell cycle arrest 1: Homo sapiens Lung | Cell Line, Tumor   1
21. 9-aminocamptothecin apoptotic process 9-aminocamptothecin results in increased apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor   1
22. 9-aminocamptothecin cell proliferation Roscovitine Roscovitine promotes the reaction [9-aminocamptothecin results in decreased cell proliferation] 1: Homo sapiens Lung | Cell Line, Tumor   1
23. 9-aminocamptothecin cell proliferation olomoucine olomoucine promotes the reaction [9-aminocamptothecin results in decreased cell proliferation] 1: Homo sapiens Lung | Cell Line, Tumor   1
24. 9-methoxycamptothecin regulation of tumor necrosis factor-mediated signaling pathway 9-methoxycamptothecin affects regulation of tumor necrosis factor-mediated signaling pathway 1: Homo sapiens Cell Line, Tumor
2 genes: CASP8 | TNF 		1
25. 9-methoxycamptothecin response to oxidative stress 9-methoxycamptothecin affects response to oxidative stress 1: Homo sapiens Cell Line, Tumor
4 genes: BCL2 | BCL2L1 | PTGS2 | TP53 		1
26. 9-methoxycamptothecin cellular response to toxic substance 9-methoxycamptothecin affects cellular response to toxic substance 1: Homo sapiens Ovary | Cell Line, Tumor   1
27. 9-methoxycamptothecin cellular response to toxic substance 9-methoxycamptothecin affects cellular response to toxic substance 1: Homo sapiens HeLa Cells   1
28. 9-methoxycamptothecin positive regulation of apoptotic process 9-methoxycamptothecin affects positive regulation of apoptotic process 1: Homo sapiens HeLa Cells
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
29. 9-methoxycamptothecin positive regulation of apoptotic process 9-methoxycamptothecin affects positive regulation of apoptotic process 1: Homo sapiens Ovary | Tumor Cells, Cultured
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
30. 9-methoxycamptothecin mitotic cell cycle arrest 9-methoxycamptothecin affects mitotic cell cycle arrest 1: Homo sapiens Ovary | Tumor Cells, Cultured
3 genes: CDKN1A | CDKN1B | TP53 		1
31. 9-methoxycamptothecin mitotic cell cycle arrest 9-methoxycamptothecin affects mitotic cell cycle arrest 1: Homo sapiens HeLa Cells
3 genes: CDKN1A | CDKN1B | TP53 		1
32. 9-methoxycamptothecin positive regulation of apoptotic process CASP3 [9-methoxycamptothecin results in increased activity of CASP3 protein] which affects positive regulation of apoptotic process 1: Homo sapiens HeLa Cells
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
33. 9-methoxycamptothecin positive regulation of apoptotic process CASP3 [9-methoxycamptothecin results in increased activity of CASP3 protein] which affects positive regulation of apoptotic process 1: Homo sapiens Ovary | Tumor Cells, Cultured
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
34. 9-methoxycamptothecin positive regulation of apoptotic process CASP8 [9-methoxycamptothecin results in increased activity of CASP8 protein] which affects positive regulation of apoptotic process 1: Homo sapiens Ovary | Tumor Cells, Cultured
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
35. 9-methoxycamptothecin positive regulation of apoptotic process CASP9 [9-methoxycamptothecin results in increased activity of CASP9 protein] which affects positive regulation of apoptotic process 1: Homo sapiens Ovary | Tumor Cells, Cultured
12 genes: BAD | BAX | BCL2L1 | CASP3 | CASP8 | CASP9 | FAS | FASLG | JUN | PTGS2 | TNF | TP53 		1
36. 9-methoxycamptothecin positive regulation of extrinsic apoptotic signaling pathway 9-methoxycamptothecin affects positive regulation of extrinsic apoptotic signaling pathway 1: Homo sapiens Cell Line, Tumor
2 genes: CASP8 | FAS 		1
37. 9-methoxycamptothecin positive regulation of intrinsic apoptotic signaling pathway 9-methoxycamptothecin affects positive regulation of intrinsic apoptotic signaling pathway 1: Homo sapiens Cell Line, Tumor
5 genes: BAD | BAX | BCL2 | BCL2L1 | TP53 		1
38. 9-methoxycamptothecin positive regulation of tumor necrosis factor biosynthetic process 9-methoxycamptothecin affects positive regulation of tumor necrosis factor biosynthetic process 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
39. 9-methoxycamptothecin positive regulation of tumor necrosis factor biosynthetic process 9-methoxycamptothecin affects positive regulation of tumor necrosis factor biosynthetic process 1: Homo sapiens HeLa Cells   1
40. 9-methoxycamptothecin positive regulation of Fas signaling pathway 9-methoxycamptothecin affects positive regulation of Fas signaling pathway 1: Homo sapiens HeLa Cells   1
41. 9-methoxycamptothecin positive regulation of Fas signaling pathway 9-methoxycamptothecin affects positive regulation of Fas signaling pathway 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
42. 9-methoxycamptothecin positive regulation of FasL biosynthetic process 9-methoxycamptothecin affects positive regulation of FasL biosynthetic process 1: Homo sapiens HeLa Cells   1
43. 9-methoxycamptothecin positive regulation of FasL biosynthetic process 9-methoxycamptothecin affects positive regulation of FasL biosynthetic process 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
44. 9-methoxycamptothecin positive regulation of reactive oxygen species metabolic process 9-methoxycamptothecin affects positive regulation of reactive oxygen species metabolic process 1: Homo sapiens HeLa Cells
2 genes: CDKN1A | TP53 		1
45. 9-methoxycamptothecin positive regulation of reactive oxygen species metabolic process 9-methoxycamptothecin affects positive regulation of reactive oxygen species metabolic process 1: Homo sapiens Ovary | Cell Line, Tumor
2 genes: CDKN1A | TP53 		1
46. Camptothecin apoptotic process Camptothecin results in increased apoptotic process 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured
47 genes: AIFM3 | AKT1 | ATG5 | ATM | BAX | BBC3 | BCL2 | BCL2L1 | BECN1 | BID | BIRC5 | BRCA1 | CASP2 | CASP3 | CASP7 | CASP8 | CASP9 | CFLAR | CHEK1 | CHEK2 | CLPTM1L | CYCS | DDIT3 | E2F1 | EI24 | EP300 | FAS | GADD45A | GADD45G | IL1B | LGALS1 | MAP3K5 | MAP3K7 | MAPK1 | MAPK3 | MAPT | PARP1 | PLK3 | PPP2CA | PPP2R1A | RB1 | SIRT1 | SQSTM1 | TNFSF9 | TP53 | TRP53 | XIAP 		1
47. Camptothecin apoptotic process mithramycin A mithramycin A inhibits the reaction [Camptothecin results in increased apoptotic process] 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured
47 genes: AIFM3 | AKT1 | ATG5 | ATM | BAX | BBC3 | BCL2 | BCL2L1 | BECN1 | BID | BIRC5 | BRCA1 | CASP2 | CASP3 | CASP7 | CASP8 | CASP9 | CFLAR | CHEK1 | CHEK2 | CLPTM1L | CYCS | DDIT3 | E2F1 | EI24 | EP300 | FAS | GADD45A | GADD45G | IL1B | LGALS1 | MAP3K5 | MAP3K7 | MAPK1 | MAPK3 | MAPT | PARP1 | PLK3 | PPP2CA | PPP2R1A | RB1 | SIRT1 | SQSTM1 | TNFSF9 | TP53 | TRP53 | XIAP 		1
48. Camptothecin apoptotic process Chromomycin A3 Chromomycin A3 inhibits the reaction [Camptothecin results in increased apoptotic process] 1: Rattus norvegicus Cerebral Cortex | Neurons | Cells, Cultured
47 genes: AIFM3 | AKT1 | ATG5 | ATM | BAX | BBC3 | BCL2 | BCL2L1 | BECN1 | BID | BIRC5 | BRCA1 | CASP2 | CASP3 | CASP7 | CASP8 | CASP9 | CFLAR | CHEK1 | CHEK2 | CLPTM1L | CYCS | DDIT3 | E2F1 | EI24 | EP300 | FAS | GADD45A | GADD45G | IL1B | LGALS1 | MAP3K5 | MAP3K7 | MAPK1 | MAPK3 | MAPT | PARP1 | PLK3 | PPP2CA | PPP2R1A | RB1 | SIRT1 | SQSTM1 | TNFSF9 | TP53 | TRP53 | XIAP 		1
49. Camptothecin nucleic acid phosphodiester bond hydrolysis Camptothecin results in increased nucleic acid phosphodiester bond hydrolysis 1: Homo sapiens  
2 genes: RAD50 | TDP1 		1
50. Camptothecin nucleic acid phosphodiester bond hydrolysis gemcitabine gemcitabine promotes the reaction [Camptothecin results in increased nucleic acid phosphodiester bond hydrolysis] 1: Homo sapiens  
2 genes: RAD50 | TDP1 		1
1–50 of 450 results.
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