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Chemical Cantharidin

Name Cantharidin
CAS Type 1 Name 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
Equivalent Terms Cantharides | Cantharidine
CAS Registry Number 56-25-7
Definition A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
Structure Cantharidin
Top Interacting
Genes
MeSH® ID D002193
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Benzofurans Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Cantharidin Has associated genes Has associated diseases Has associated phenotype references

Top ↑ Descendants

Cantharidin Has associated genes Has associated diseases Has associated phenotype references
  2-tetradecylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
  CAN 032
  cantharidin methylimide
  demethylcantharidin
  disodium cantharidin
  hexahydro-3a,7a-dimethyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione
  N-benzylcantharidinamide
  N-farnesyl-norcantharimide
  N-farnesyloxy-norcantharimide
  N-hydroxycantharidinimide