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Chemical Cardiac Glycosides

1–50 of 319 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. bufalin regulation of blood pressure bufalin results in increased regulation of blood pressure 1: Rattus norvegicus Cardiovascular System
2 genes: NOS2 | PTGS2
1
2. bufalin cell migration bufalin results in decreased cell migration 1: Homo sapiens Liver | Cell Line, Tumor
3 genes: MMP2 | RHOA | VEGFA
1
3. bufalin positive regulation of apoptotic process bufalin results in increased positive regulation of apoptotic process 1: Homo sapiens Bone and Bones | Cell Line, Tumor
19 genes: AKT1 | APAF1 | CASP3 | CASP9 | DDIT3 | ENDOG | FAS | FASLG | IL1B | JUN | MAPK8 | MAPK9 | MMP2 | MMP9 | NOS2 | PTGS2 | RELA | SOS1 | TNF
1
4. bufalin negative regulation of G2/M transition of mitotic cell cycle bufalin results in increased negative regulation of G2/M transition of mitotic cell cycle 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
5. bufalin negative regulation of NIK/NF-kappaB signaling bufalin results in increased negative regulation of NIK/NF-kappaB signaling 1: Homo sapiens Bone and Bones | Cell Line, Tumor 1 gene: RELA 1
6. bufalin activation of protein kinase B activity bufalin results in decreased activation of protein kinase B activity 1: Homo sapiens Bone and Bones | Cell Line, Tumor 1 gene: AKT1 1
7. bufalin activation of protein kinase B activity HSPB1 HSPB1 protein inhibits the reaction [bufalin results in decreased activation of protein kinase B activity] 1: Homo sapiens Bone and Bones | Cell Line, Tumor 1 gene: AKT1 1
8. bufalin positive regulation of apoptotic process HSPB1 HSPB1 protein inhibits the reaction [bufalin results in increased positive regulation of apoptotic process] 1: Homo sapiens Bone and Bones | Cell Line, Tumor
19 genes: AKT1 | APAF1 | CASP3 | CASP9 | DDIT3 | ENDOG | FAS | FASLG | IL1B | JUN | MAPK8 | MAPK9 | MMP2 | MMP9 | NOS2 | PTGS2 | RELA | SOS1 | TNF
1
9. bufalin negative regulation of NIK/NF-kappaB signaling HSPB1 HSPB1 protein inhibits the reaction [bufalin results in increased negative regulation of NIK/NF-kappaB signaling] 1: Homo sapiens Bone and Bones | Cell Line, Tumor 1 gene: RELA 1
10. bufalin positive regulation of apoptotic process bufalin results in increased positive regulation of apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor
19 genes: AKT1 | APAF1 | CASP3 | CASP9 | DDIT3 | ENDOG | FAS | FASLG | IL1B | JUN | MAPK8 | MAPK9 | MMP2 | MMP9 | NOS2 | PTGS2 | RELA | SOS1 | TNF
1
11. bufalin positive regulation of reactive oxygen species biosynthetic process bufalin results in increased positive regulation of reactive oxygen species biosynthetic process 1: Homo sapiens Lung | Cell Line, Tumor   1
12. bufalin positive regulation of cell death Acetylcysteine Acetylcysteine inhibits the reaction [bufalin results in increased positive regulation of cell death] 1: Homo sapiens Lung | Cell Line, Tumor
3 genes: FAS | IL1B | PTGS2
1
13. bufalin positive regulation of mitochondrial membrane potential bufalin results in decreased positive regulation of mitochondrial membrane potential 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: AKT1 | MYC
1
14. bufalin cell death bufalin results in increased cell death 1: Homo sapiens MCF-7 Cells   1
15. bufalin cell proliferation bufalin results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells
7 genes: AKT1 | AR | BCL2 | MYC | TNF | TPT1 | VEGFA
1
16. bufalin apoptotic process bufalin results in increased apoptotic process 1: Danio rerio Embryo, Nonmammalian
16 genes: AKT1 | APAF1 | BCL2 | CASP3 | CASP9 | CYCS | DDIT3 | FAS | FASLG | IL1B | MAP2K7 | MAPK1 | MAPK3 | PARP1 | ROCK1 | TNF
1
17. cinobufagin cell proliferation cinobufagin results in decreased cell proliferation 1: Homo sapiens Hep G2 Cells
5 genes: BAX | BCL2 | GSK3B | MYC | PCNA
1
18. cinobufagin apoptotic process cinobufagin results in increased apoptotic process 1: Homo sapiens Hep G2 Cells
6 genes: BAX | BCL2 | BIRC2 | BIRC5 | PARP1 | XIAP
1
19. cinobufagin cell cycle cinobufagin results in decreased cell cycle 1: Homo sapiens Hep G2 Cells
4 genes: BIRC5 | CCNA2 | CDK2 | CDKN1A
1
20. cinobufagin calcium-mediated signaling cinobufagin results in increased calcium-mediated signaling 1: Homo sapiens Hep G2 Cells   1
21. cinobufagin cell proliferation MAPK1 MAPK1 protein inhibits the reaction [cinobufagin results in decreased cell proliferation] 1: Homo sapiens Hep G2 Cells
5 genes: BAX | BCL2 | GSK3B | MYC | PCNA
1
22. cinobufagin negative regulation of cell proliferation cinobufagin affects negative regulation of cell proliferation 1: Homo sapiens Bone and Bones | Cell Line, Tumor
3 genes: BAX | BCL2 | CDKN1A
1
23. cinobufagin positive regulation of cell cycle arrest cinobufagin affects positive regulation of cell cycle arrest 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
24. cinobufagin positive regulation of apoptotic process cinobufagin affects positive regulation of apoptotic process 1: Homo sapiens Bone and Bones | Cell Line, Tumor
3 genes: BAX | GSK3B | RELA
1
25. cinobufagin I-kappaB kinase/NF-kappaB signaling cinobufagin affects I-kappaB kinase/NF-kappaB signaling Bone and Bones | Cell Line, Tumor 1 gene: BIRC2 1
26. cinobufagin positive regulation of apoptotic process SB 216763 SB 216763 promotes the reaction [cinobufagin affects positive regulation of apoptotic process] 1: Homo sapiens Bone and Bones | Cell Line, Tumor
3 genes: BAX | GSK3B | RELA
1
27. cinobufagin cell death cinobufagin results in increased cell death 1: Homo sapiens MCF-7 Cells   1
28. cinobufagin cell proliferation cinobufagin results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells
5 genes: BAX | BCL2 | GSK3B | MYC | PCNA
1
29. Digitalis Glycosides regulation of heart rate Digitalis Glycosides results in decreased regulation of heart rate 1: Homo sapiens Heart   1
30. Digitalis Glycosides regulation of blood pressure Digitalis Glycosides affects regulation of blood pressure 1: Homo sapiens Blood Vessels   1
31. Digitonin manganese ion transmembrane transport Digitonin results in increased manganese ion transmembrane transport 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
32. Digitonin manganese ion transmembrane transport Manganese [Digitonin results in increased manganese ion transmembrane transport] which results in increased abundance of Manganese 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
33. Digitonin cellular metabolic process Digitonin results in decreased cellular metabolic process 1: Homo sapiens HEK293 Cells   1
34. Digitonin cellular metabolic process Digitonin results in decreased cellular metabolic process 1: Homo sapiens Hep G2 Cells   1
35. Digitonin cell death Digitonin results in increased cell death 1: Homo sapiens Hep G2 Cells   1
36. Digitonin cell death Digitonin results in increased cell death 1: Homo sapiens HEK293 Cells   1
37. Digitoxigenin cell death Digitoxigenin results in increased cell death 1: Homo sapiens Myeloid Cells | Cell Line, Tumor   1
38. Digitoxin regulation of blood pressure Digitoxin results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System
2 genes: ATP1A1 | NOS3
2
39. Digitoxin regulation of heart rate Digitoxin results in decreased regulation of heart rate 1: Homo sapiens Heart   2
40. Digitoxin apoptotic process 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | TNF 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Digitoxin inhibits the reaction [TNF protein results in increased apoptotic process]] 1: Homo sapiens Umbilical Cord | Veins | Endothelial Cells | Cells, Cultured
14 genes: BIRC5 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | CYCS | IL1B | MAPK1 | MAPK3 | NFKB1 | NFKBIA | TP53
1
41. Digitoxin apoptotic process TNF Digitoxin inhibits the reaction [TNF protein results in increased apoptotic process] 1: Homo sapiens Umbilical Cord | Veins | Endothelial Cells | Cells, Cultured
14 genes: BIRC5 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | CYCS | IL1B | MAPK1 | MAPK3 | NFKB1 | NFKBIA | TP53
1
42. Digitoxin regulation of heart rate Diltiazem [Diltiazem co-treated with Digitoxin] results in decreased regulation of heart rate 1: Homo sapiens Heart   1
43. Digitoxin positive regulation of viral life cycle Digitoxin results in decreased positive regulation of viral life cycle 1: Sus scrofa Testis | Epithelial Cells | Cell Line   1
44. Digitoxin induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process Digitoxin results in decreased induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process 1: Sus scrofa Testis | Epithelial Cells | Cell Line   1
45. Digitoxin cell death Digitoxin results in increased cell death 1: Homo sapiens Blood | Cell Line, Tumor 1 gene: CDKN1B 1
46. Digitoxin cell death Digitoxin results in increased cell death 1: Homo sapiens K562 Cells 1 gene: CDKN1B 1
47. Digoxin cell death Digoxin results in increased cell death 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
48. Digoxin cell death 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased cell death] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
49. Digoxin histamine secretion mediated by immunoglobulin p-Methoxy-N-methylphenethylamine Digoxin promotes the reaction [p-Methoxy-N-methylphenethylamine results in increased histamine secretion mediated by immunoglobulin] 1: Rattus norvegicus Peritoneum | Mast Cells | Cells, Cultured   1
50. Digoxin histamine secretion mediated by immunoglobulin TAC1 Digoxin promotes the reaction [TAC1 protein results in increased histamine secretion mediated by immunoglobulin] Peritoneum | Mast Cells | Cells, Cultured   1
1–50 of 319 results.