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Chemical Chromans

1–50 of 703 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one superoxide dismutase activity Acetaminophen | SB 657510 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one inhibits the reaction [SB 657510 inhibits the reaction [Acetaminophen results in decreased superoxide dismutase activity]] 1: Mus musculus Liver   1
2. 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one leukocyte migration involved in inflammatory response Acetaminophen | SB 657510 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one inhibits the reaction [SB 657510 inhibits the reaction [Acetaminophen results in increased leukocyte migration involved in inflammatory response]] 1: Mus musculus Liver   1
3. 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane regulation of the force of heart contraction by chemical signal 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane affects regulation of the force of heart contraction by chemical signal 1: Cavia porcellus Cardiovascular System   1
4. 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane positive regulation of potassium ion export across plasma membrane rutecarpine 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane inhibits the reaction [rutecarpine results in increased positive regulation of potassium ion export across plasma membrane] 1: Rattus norvegicus Colon | Intestinal Mucosa   1
5. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid autophagy 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in increased autophagy 1: Rattus norvegicus Liver | Hepatocytes | Cell Line, Tumor   1
6. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid membrane lipid catabolic process Ascorbic Acid | ferrous chloride | Hydrogen Peroxide 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [[Hydrogen Peroxide co-treated with ferrous chloride co-treated with Ascorbic Acid] results in increased membrane lipid catabolic process] 1: Rattus norvegicus Prosencephalon | Synapses | Cell Membrane   1
7. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid membrane lipid catabolic process 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased membrane lipid catabolic process 1: Rattus norvegicus Liver   1
8. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased response to oxidative stress 1: Homo sapiens Fibroblasts | Cells, Cultured
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
9. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased apoptotic process 1: Rattus norvegicus Hepatocytes | Cells, Cultured
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
10. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Hemin 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Hemin results in increased apoptotic process] 1: Mus musculus Cell Line | Cerebral Cortex | Microvessels
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
11. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death 1-Methyl-4-phenylpyridinium 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cell death] 1: Rattus norvegicus PC12 Cells   1
12. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death low density lipoprotein triglyceride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [low density lipoprotein triglyceride results in increased cell death] 1: Homo sapiens Macrophages | Cells, Cultured   1
13. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Vitamin A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased apoptotic process] Sertoli Cells | Cells, Cultured
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
14. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Dexamethasone 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Dexamethasone results in increased apoptotic process] 1: Mus musculus Lymphocytes | Cell Line, Tumor
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
15. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress Tretinoin 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tretinoin results in increased response to oxidative stress] 1: Rattus norvegicus Sertoli Cells | Cells, Cultured
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
16. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress Vitamin A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased response to oxidative stress] 1: Rattus norvegicus Sertoli Cells | Cells, Cultured
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
17. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress anhydrovitamin A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anhydrovitamin A results in increased response to oxidative stress] 1: Homo sapiens Jurkat Cells
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
18. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death ferric chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [ferric chloride results in increased cell death] 1: Mus musculus Cerebral Cortex | Neurons | Cells, Cultured   1
19. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death Azathioprine 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Azathioprine results in increased cell death] 1: Rattus norvegicus Hepatocytes | Cells, Cultured   1
20. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress Sevoflurane 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Sevoflurane results in increased response to oxidative stress] 1: Homo sapiens Neutrophils
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
21. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress Tetrachlorodibenzodioxin 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased response to oxidative stress] 1: Oryctolagus cuniculus Chondrocytes | Cells, Cultured
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
22. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Tetrachlorodibenzodioxin 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased apoptotic process] 1: Oryctolagus cuniculus Chondrocytes | Cells, Cultured
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
23. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Ursodeoxycholic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Ursodeoxycholic Acid results in increased apoptotic process] 1: Homo sapiens Stomach | Cell Line, Tumor
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
24. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death Hydrogen Peroxide 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Hydrogen Peroxide results in increased cell death] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
25. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death Iron Compounds 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Iron Compounds results in increased cell death] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
26. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process DMPK | methylmercuric chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [[DMPK mutant form co-treated with methylmercuric chloride] results in increased apoptotic process] 1: Mus musculus Myoblasts | Cell Line
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
27. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Cisplatin 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cisplatin results in increased apoptotic process] 1: Sus scrofa Kidney Tubules | Cell Line
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
28. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process 3-Hydroxyanthranilic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [3-Hydroxyanthranilic Acid results in increased apoptotic process] 1: Homo sapiens U937 Cells
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
29. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell proliferation 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor
10 genes: AKT1 | BAX | BCL2 | HGF | IL1A | MAP2K1 | SRC | TGFB1 | THPO | VEGFA
1
30. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid membrane lipid catabolic process Ascorbic Acid | Iron 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in increased membrane lipid catabolic process] 1: Homo sapiens Spermatozoa   1
31. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid membrane lipid catabolic process Iron 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Iron results in increased membrane lipid catabolic process] 1: Rattus norvegicus Cerebral Cortex   1
32. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid response to oxidative stress manganese chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride results in increased response to oxidative stress] 1: Rattus norvegicus Basal Ganglia
16 genes: AIFM1 | AKT1 | BCL2 | CAT | CYCS | EPAS1 | G6PD | LPO | MAP2K1 | PON2 | PRDX6 | PRKCD | SOD1 | SOD2 | SOD3 | TFAM
1
33. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid regulation of p38MAPK cascade manganese chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride affects regulation of p38MAPK cascade] 1: Rattus norvegicus Basal Ganglia
2 genes: AGER | HGF
1
34. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid positive regulation of cysteine-type endopeptidase activity manganese chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride affects positive regulation of cysteine-type endopeptidase activity] 1: Rattus norvegicus Basal Ganglia 1 gene: FYN 1
35. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid lipid oxidation manganese chloride 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride results in increased lipid oxidation] 1: Rattus norvegicus Basal Ganglia   1
36. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid cell death APP | Buthionine Sulfoximine 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [[APP protein modified form co-treated with Buthionine Sulfoximine] results in increased cell death] 1: Rattus norvegicus Hippocampus   1
37. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid reactive oxygen species metabolic process 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased reactive oxygen species metabolic process 1: Homo sapiens Fibroblasts | Cells, Cultured
4 genes: BCL2 | CAT | SOD1 | SOD2
1
38. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid MAP kinase activity Vitamin A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased MAP kinase activity] 1: Rattus norvegicus Sertoli Cells
4 genes: MAPK1 | MAPK3 | MAPK8 | MAPK9
1
39. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid reactive oxygen species metabolic process Vitamin A 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Vitamin A results in increased reactive oxygen species metabolic process] 1: Rattus norvegicus Sertoli Cells
4 genes: BCL2 | CAT | SOD1 | SOD2
1
40. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid negative regulation of reactive oxygen species biosynthetic process 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid affects negative regulation of reactive oxygen species biosynthetic process 1: Rattus norvegicus Astrocytes | Cell Line   1
41. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid DNA damage response, detection of DNA damage Ethacrynic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid promotes the reaction [Ethacrynic Acid results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens HCT116 Cells 1 gene: PARP1 1
42. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid calcium ion import across plasma membrane Pesticides 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Pesticides results in increased calcium ion import across plasma membrane] 1: Rattus norvegicus Sertoli Cells   1
43. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid regulation of calcium ion transmembrane transport via high voltage-gated calcium channel Pesticides 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Pesticides affects regulation of calcium ion transmembrane transport via high voltage-gated calcium channel] 1: Rattus norvegicus Sertoli Cells   1
44. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid positive regulation of necrotic cell death Pesticides 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Pesticides results in increased positive regulation of necrotic cell death] 1: Rattus norvegicus Sertoli Cells   1
45. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid calcium ion import across plasma membrane glyphosate 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [glyphosate results in increased calcium ion import across plasma membrane] 1: Rattus norvegicus Sertoli Cells   1
46. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid positive regulation of mast cell degranulation 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid results in decreased positive regulation of mast cell degranulation 1: Mus musculus Mast Cells   1
47. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Arsenic Trioxide | Ethacrynic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in increased apoptotic process]] 1: Homo sapiens HL-60 Cells
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
48. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid regulation of mitochondrial membrane potential Arsanilic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Arsanilic Acid affects regulation of mitochondrial membrane potential] 1: Rattus norvegicus Kidney | Epithelial Cells | Cell Line
4 genes: BAX | BCL2 | SOD1 | SOD2
1
49. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid apoptotic process Arsanilic Acid 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Arsanilic Acid results in increased apoptotic process] 1: Rattus norvegicus Kidney | Epithelial Cells | Cell Line
24 genes: AIFM1 | AKT1 | APAF1 | BAX | BCL2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CYCS | DAPK1 | FAS | IL1A | IL1B | MAP3K5 | MAPK1 | MAPK3 | PARP1 | PRKCD | RIPK2 | TNF | TNFSF10
1
50. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid reactive oxygen species biosynthetic process Silver 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Silver analog results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Lymphocytes | Cell Line   1
1–50 of 703 results.