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Chemical Cocaine

Name Cocaine
CAS Type 1 Name 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
Equivalent Terms Cocaine HCl | Cocaine Hydrochloride | HCl, Cocaine | Hydrochloride, Cocaine
CAS Registry Number 50-36-2
Definition An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
Structure Cocaine
Top Interacting
Genes
MeSH® ID D003042
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Aza Compounds Has associated genes Has associated diseases Azabicyclo Compounds Has associated genes Has associated diseases Tropanes Has associated genes Has associated diseases Cocaine Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated exposure references Tropanes Has associated genes Has associated diseases Cocaine Has associated genes Has associated diseases
3. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Bridged-Ring Has associated genes Has associated diseases Tropanes Has associated genes Has associated diseases Cocaine Has associated genes Has associated diseases
4. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Bridged Compounds Has associated genes Has associated diseases Has associated exposure references Bicyclo Compounds Has associated genes Has associated diseases Has associated exposure references Bicyclo Compounds, Heterocyclic Has associated genes Has associated diseases Azabicyclo Compounds Has associated genes Has associated diseases Tropanes Has associated genes Has associated diseases Cocaine Has associated genes Has associated diseases

Top ↑ Descendants

Cocaine Has associated genes Has associated diseases
  (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester Has associated genes Has associated diseases
  2,3-dehydrococaine
  2-carbomethoxy-3-(3'-iodophenyl)tropane
  2-fluoroethyl 8-(3-iodoprop-2-en-1-yl)-3-(4-iodophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate
  2'-fluoroethyl 8-methyl-3-(4-chlorophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate
  2'-fluoroethyl 8-methyl-3-(4-methylphenyl)-8-azabicyclo(3.2.1)octane-2-carboxylate
  2-propanoyl-3-(2-naphthyl)-tropane
  2-propanoyl-3-(4-tolyl)tropane Has associated diseases
  3-((2'-hydroxy-4'-iodobenzoyl)oxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid isopropyl ester
  3-(3-fluoro-4-methylphenyl)nortropane-2-carboxylic acid methyl ester
  3-(4'-azido-3'-iodobiphenyl-4-yl)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester
  3-(4-chlorophenyl)tropane-2-carboxylic acid methyl ester
  3-(4-ethyl-3-iodophenyl)nortropane-2-carboxylic acid methyl ester
  3-(4-fluorobenzoyloxy)tropane
  3-(4-iodophenyl)tropan-2beta-carboxylic acid phenyl ester
  3beta-(2-fluoromethylphenyl)tropane-2beta-carboxylic acid methyl ester
  3beta-(4-fluoromethylphenyl)tropane-2beta-carboxylic acid methyl ester
  3-beta-(4'-n-propyl)nortropane-2-beta-carboxylic acid methyl ester
  3'-hydroxy-4'-methoxycocaine
  3-hydroxybenzoylecgonine Has associated diseases
  3'-hydroxycocaine
  3-iodo-4-azidococaine
  4,5,6,7,8,9,10,11,13,17a,18,19,20,21,22,22a-hexadecahydro-23-methyl-14,17-etheno-19,22-imino-1H-cyclohept(c)(1,9)oxaazacyclononadecine-3,12-dione
  4'-fluorococaine
  4'-hydroxy-3'-methoxycocaine
  4-hydroxybenzoylecgonine Has associated diseases
  4'-hydroxycocaine Has associated diseases
  4'-iodococaine
  (4'-isopropenyl-phenyl)nortropane-2-beta-carboxylic acid methylester
  4'-isopropylnortropane-2-beta-carboxylic acid methyl ester
  4'-phenylcocaine
  5,6,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-methyl-11,14-etheno-16,19-iminocyclohept(c)(1,9)oxaazacyclohexadecine-3,9(1H,4H)-dione
  6-(3-(benzoyloxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxoamido)hexanoic acid
  6-methyl-3-(4-iodo)phenyltropane-2-carboxylic acid methyl ester
  7-methyl-3-(4-iodo)phenyltropane-2-carboxylic acid methyl ester
  8-(2-fluoroethyl)-3-(4-iodophenyl)-8-azabicyclo(3.2.1)octane-2-carboxylic acid methyl ester
  8-((E)-4-fluoro-but-2-enyl)-3beta-p-tolyl-8-aza-bicyclo(3.2.1)octane-2beta-carboxylic acid methyl ester
  8-hydroxynorcocaine
  8-methyl-3-(4-methylphenyl)tropane--2-carboxylic acid N-methyl-N-(4-nitrobenzo-2-oxa-1,3-diazol-7-yl)ethanolamine ester
  8-oxanorcocaine
  aluminum hydroxide, cimetidine, cocaine, hydroxyzine, morphine drug combination
  anhydroecgonine methyl ester Has associated genes Has associated diseases
  anhydroecgonine methyl ester N-oxide
  benzoylecgonine Has associated genes Has associated diseases
  benzoylecgonine isopropyl ester
  benzoylnorecgonine
  Bonain's liquid
  cinnamoylcocaine
  cocaethylene Has associated genes Has associated diseases
  cocaine benzoyl thioester
  cocaine, dipicrylaminate drug combination
  cocaine methiodide Has associated diseases
  cocaine N-oxide
  Crack Cocaine Has associated genes Has associated diseases
  dichloropane
  difluoropine
  ecgonidine
  ecgonine Has associated diseases
  ecgonine methyl ester Has associated genes Has associated diseases
  ethyl ecgonine
  methyl 3-benzoyloxy-7-methoxy-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate
  methyl-8-((2-(fluoromethyl)cyclopropyl)methyl)-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylate
  N-(2-fluoroethyl)-3beta-(4-iodophenyl)-8-methyl-8-azabicyclo(3.2.1)octane-2alpha-carboxamide
  N-allylnorcocaine
  N-benzoylnormethylecgonine
  N-formylnorcocaine
  N-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane Has associated diseases
  N-nor-3-(4'-ethylphenyl)tropane-2-carboxylic acid methyl ester
  N-nor-3-(4'-iodophenyl)tropane-2-carboxylic acid methyl ester
  noranhydroecgonine
  norcocaethylene
  norcocaine Has associated diseases
  norcocaine nitroxide
  nortropacocaine
  pseudococaine Has associated diseases
  RTI-113 Has associated genes Has associated diseases
  RTI 117
  RTI 121 Has associated genes Has associated diseases
  RTI 130
  RTI 352
  RTI 55 Has associated genes Has associated diseases
  RTI 82
  RTI-COC 32
  SNC-rCTB vaccine
  TEC solution
  trimethylstannyl-(2-carbomethoxy-3-(4-phenyl)tropane)
  tropacocaine Has associated genes Has associated diseases
  troparil
  tropoxene