Skip navigation

Chemical Cyclophosphamide

Name Cyclophosphamide
CAS Type 1 Name (+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate
Equivalent Terms Anhydrous, Cyclophosphamide | B518 | B 518 | B-518 | Cyclophosphamide Anhydrous | Cyclophosphamide Monohydrate | Cyclophosphamide, (R)-Isomer | Cyclophosphamide, (S)-Isomer | Cyclophosphane | Cytophosphan | Cytophosphane | Cytoxan | Endoxan | Monohydrate, Cyclophosphamide | Neosar | NSC26271 | NSC 26271 | NSC-26271 | Procytox | Sendoxan
CAS Registry Number 50-18-0
Definition Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Structure Cyclophosphamide
Curator Note For additional curated data about phosphorus, please also see Phosphorus and its chemical descendants.
Top Interacting
Genes
MeSH® ID D003520
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Halogenated Has associated genes Has associated diseases Has associated exposure references Mustard Compounds Has associated genes Has associated diseases Has associated exposure references Nitrogen Mustard Compounds Has associated genes Has associated diseases Phosphoramide Mustards Has associated genes Has associated diseases Cyclophosphamide Has associated genes Has associated diseases
2. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Organophosphorus Compounds Has associated genes Has associated diseases Has associated exposure references Phosphoramides Has associated genes Has associated diseases Has associated exposure references Phosphoramide Mustards Has associated genes Has associated diseases Cyclophosphamide Has associated genes Has associated diseases

Top ↑ Descendants

Cyclophosphamide Has associated genes Has associated diseases
  2-dechloroethylcyclophosphamide
  3-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)cyclophosphamide
  3-hydroxycyclophosphamide
  3-methoxy-1,3,5(10)-estratriene-17(R)-spiro-6'-(2'-(bis-(2-chloroethyl)amino)-2'-oxo-1'-oxa-3'-aza-2'-phosphorane)
  3-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane Has associated genes Has associated diseases
  4,6-diphenylcyclophosphamide
  4-glutathionylcyclophosphamide
  4-hydroperoxydechlorocyclophosphamide Has associated diseases
  4-hydroperoxydidechlorocloclophosphamide
  4-hydroxycyclophosphamide Has associated genes Has associated diseases
  4-hydroxyperoxycyclophosphamide
  4-ketocyclophosphamide
  4-methylcyclophosphamide
  4-peroxycyclophosphamide
  4-phenylcyclophosphamide
  4-S-ethanolsulfido-cyclophosphamide
  4-S-(hexane-6-ol)sulfidocyclophosphamide
  4-S-(propionic acid)sulfidocyclophosphamide
  4-ureidooxycyclophosphamide
  5,5-dimethylcyclophosphamide
  5-chlorocyclophosphamide
  5-fluorocyclophosphamide
  7+3 protocol
  AAABC protocol
  ABCDV protocol
  ABCM protocol
  ABC protocol
  ACE protocol 1 Has associated diseases
  ACFM protocol Has associated diseases
  ACF protocol Has associated diseases
  ACFT protocol
  AcFuCy protocol
  ACMFVP protocol
  ACM protocol
  ACOB regimen
  ACOMLA protocol Has associated diseases
  ACOPA II protocol
  ACOP-E protocol
  ACOP protocol 2
  ACP protocol
  AC protocol Has associated diseases
  ACT regimen
  ACVB protocol
  ADOC protocol
  AIEOP acute lymphoblastic leukemia protocol Has associated diseases
  alcophosphamide
  ALL-1 protocol
  ALL-BFM-95 protocol Has associated diseases
  ANAVACYM protocol Has associated diseases
  ARA-COP protocol
  Asta Z 7557
  AVCF protocol Has associated diseases
  AVCT protocol
  AVLF protocol
  B-8801 protocol
  BACOD protocol Has associated diseases
  BACOD-VP16 protocol
  BACT protocol
  BAEC protocol Has associated genes Has associated diseases
  BCD protocol Has associated diseases
  BCHE protocol
  BCOMM protocol
  BCPE protocol
  BCPP protocol
  BCP protocol
  BCVP protocol
  BEACOPP protocol Has associated genes Has associated diseases
  BECALM protocol
  BEMOP-CA protocol
  Berlin-Frankfurt-Muenster protocol II
  BFM 78 protocol
  BFM-86 protocol Has associated diseases
  BFM-ALL 81 protocol Has associated diseases
  BMF phase II protocol
  BOP-CISCA-POMB-ACE regimen Has associated diseases
  BOVAPEC protocol
  BuCEt protocol
  BUCY-2 protocol Has associated diseases
  BV-CAP protocol
  BVCPP protocol Has associated diseases
  CAC protocol
  CADOM protocol
  CAD protocol 3
  CAE-P protocol
  CAEVM protocol
  CAF-PH protocol
  CAF protocol Has associated genes Has associated diseases
  CAF protocol 2 Has associated diseases
  CAFVP protocol
  CALF protocol
  CAMBO-VIP protocol
  CAM combination
  CAMEO protocol
  CAMF protocol
  CAMFTP protocol
  CAMP-L protocol
  CAMP protocol
  CAOP protocol
  CAP-1 protocol Has associated diseases
  CAPABLE protocol
  CAPE-PALE protocol
  CAPE protocol
  CAPF protocol
  CAP-M protocol
  CAP protocol 2 Has associated diseases
  CAPT protocol
  CARA protocol
  CAT combination
  CAT-G protocol
  CAVB protocol
  CAV-HEM protocol
  CAV protocol Has associated diseases
  CAV-T protocol
  CBVPM protocol
  CBV protocol Has associated genes Has associated diseases
  CCA protocol
  CCAVP16 protocol
  CCC protocol
  CCE protocol Has associated diseases
  CCOM protocol
  CCP protocol
  CCV-AV protocol
  CCVPP protocol
  CCV protocol
  CDOP protocol Has associated diseases
  CDPTH regimen
  CE-CAP protocol
  CECA protocol
  CEC protocol
  CEE protocol
  CEF regimen Has associated genes Has associated diseases
  CEFT protocol Has associated diseases
  CEMP protocol
  CEOP-B protocol
  CEO-PE protocol
  CEOP-IMVP-Dexa regimen
  CEOP-MB protocol
  CEOP protocol 1 Has associated diseases
  CEOP protocol 2
  CEP combination
  CEPP protocol
  CEP regimen
  CE protocol II Has associated diseases
  CEVAD protocol
  CEVBP protocol
  CEVP protocol
  CEV protocol
  CFMPV protocol
  CFP protocol Has associated diseases
  CF protocol
  CHAC-1 protocol
  CHAMOCA regimen
  CHAMOMA protocol
  CHAMP-5 protocol
  CHASE protocol
  CHEP protocol
  CHF protocol
  CHOEP protocol Has associated diseases
  CHOP-B protocol Has associated diseases
  CHOP protocol Has associated genes Has associated diseases
  CHOP protocol, modified
  CHOP-V-MMV protocol
  CHOP-VP16 protocol
  CHVmP-VB protocol
  CHVP protocol
  CHVP regimen
  CIOD protocol
  CIOP-Bleo protocol
  CIOP protocol
  CISCA(II)-VB(IV) protocol
  CISCA protocol
  Cis-VACD protocol
  CMB protocol
  CMCF protocol
  CMCp protocol
  CMC protocol 2
  CMED protocol
  CMF-B protocol
  CMFDV protocol
  CMFP protocol Has associated diseases
  CMFPTH regimen
  CMFPT protocol Has associated diseases
  CMF regimen Has associated genes Has associated diseases
  CMFVP protocol Has associated diseases
  CMOPP protocol Has associated diseases
  CMU protocol
  CMVP regimen
  CMxMF regimen
  CN3OP regimen
  CNV protocol
  COAP protocol Has associated diseases
  COATA protocol
  COBDP regimen
  COCE protocol
  CODBLAM IV protocol
  COFB protocol
  COFP protocol 1
  COFP protocol 2 Has associated diseases
  COF protocol
  COMB protocol
  COMET-A protocol
  COMF protocol
  COMLA protocol
  COMP-1 protocol
  (COMPADRI)-III protocol
  COMPA protocol
  COMP protocol Has associated diseases
  COMP-VAN protocol
  COMVP protocol
  COPAC protocol
  COPADEM protocol
  COPAD protocol
  COP-BLAM protocol
  COP-B protocol
  COPEP protocol
  COPE regimen Has associated diseases
  COPP-ABVD protocol Has associated diseases
  COP-PAF protocol
  COPP protocol Has associated genes Has associated diseases
  COP protocol 1
  COP protocol 2 Has associated diseases
  COPU protocol
  CPDD protocol Has associated diseases
  CP protocol Has associated diseases
  CTCb regimen Has associated diseases
  CTEC protocol
  CTVP protocol Has associated diseases
  CVACE protocol
  CVAD protocol Has associated diseases
  CVAD-V protocol
  C-VAMP protocol
  CVAP-B protocol
  CVD protocol Has associated diseases
  CVPPABO protocol
  CVPP I protocol
  CVPP regimen Has associated diseases
  CVP protocol 2
  CV protocol
  CWAP regimen
  CyADIC regimen
  cyclone protocol
  CYOMAD protocol Has associated diseases
  CYVADIC protocol Has associated diseases
  CYVEDIC protocol
  d4-cyclophosphamide
  DAC protocol
  DAC protocol 2
  DAEP protocol
  DAT-COAP regimen
  DCCM protocol
  D-CECaT regimen
  DCEP protocol Has associated diseases
  DD1 protocol
  DECAV protocol Has associated diseases
  dechloroethylcyclophosphamide Has associated genes Has associated diseases
  diiodocyclophosphamide
  DT-PACE protocol Has associated diseases
  DVP-M-CHOP protocol
  EACB protocol
  ECAPP protocol
  ECBC protocol
  ECHO protocol Has associated diseases
  ECP regimen
  EC regimen Has associated diseases
  EMA-CO protocol
  EPOCH protocol Has associated diseases
  EVAC protocol
  EVDAC regimen
  FAC-MV protocol
  FACP protocol
  FCC protocol
  FEC protocol Has associated genes Has associated diseases
  FEMP protocol
  F-MACHOP protocol Has associated diseases
  FMC protocol Has associated diseases
  GIMEMA LAL 0288 protocol
  HCOMLA protocol
  HCVAD protocol Has associated diseases
  HD-CEP regimen
  HD-CNV protocol
  HEAVD protocol
  hexa CAF protocol
  HiC-COM protocol Has associated diseases
  HM 89 protocol
  HM 91 protocol
  hyperCDT protocol Has associated diseases
  ICBV regimen
View node Ifosfamide Has associated genes Has associated diseases
  iminophosphamide
  iodocyclophosphamide
  IVAD protocol
  JAC protocol
  L-6 protocol
  LALA 87 protocol
  LMB89 protocol
  LNH-80 regimen
  LNH 84 protocol
  LNH87-2 protocol
  LNH 87 protocol Has associated diseases
  LSA(2)L(2) protocol
  LSA2-L2 protocol
  LSG15 regimen
  M-2 protocol Has associated diseases
  MACC combination
  MAC combination
  MAC conditioning regimen
  MACHO protocol
  MAC III protocol
  m-ACOD protocol Has associated diseases
  MACOP-B protocol Has associated diseases
  MACOP-B regimen
  MADDOC protocol
  mafosfamide Has associated genes Has associated diseases
  mafosfamide-lysine
  Mallinson protocol
  malmo protocol
  MAPECO protocol
  maphosphamide Has associated genes Has associated diseases
  MATCOP regimen
  M-BACOD protocol Has associated diseases
  M-BACOP protocol
  M-BACOS protocol
  m-BECOD protocol
  M-BNCOD protocol Has associated diseases
  MCC protocol
  MCHC protocol
  MCHOD protocol
  MCOP protocol
  MCP 842 regimen
  MCPD protocol
  MCPP protocol
  MDACC protocol
  MECHOP-BM protocol
  MECY protocol
  MEV-AD protocol
  MEVAP protocol
  MEV protocol
  MiCaT protocol
  MI-MIV maintenance protocol
  MiNa protocol
  MLL-93 protocol
  ML-Y1 protocol
  m-M-BACOD protocol
  MMC protocol
  MNCOP-B protocol
  MOCCA protocol
  MOPLACE protocol
  MOPLEC protocol
  MPCCV protocol
  MSK-NY-II protocol, modified Has associated diseases
  MTX-CHOP protocol
  Murphy-Bowmann protocol
  MVP-CAB protocol
  N(3)-methyl-4-(diethyldithiocarbamoyl)cyclophosphamide
  N(3)-methyl-4-(propylthio)cyclophosphamide
  N4SE protocol
  NCI PB 93-C-207 protocol
  NCVB protocol
  NEO-MACOP-B protocol
  New York protocol
  N,N-diethylcyclophosphamide Has associated diseases
  OC-HDP protocol Has associated diseases
  OPEC-D protocol
  OPEC OJEC protocol Has associated diseases
  OPEC protocol 1
  OPPA protocol
  OXAC protocol
  PAB-CAP protocol
  PACE-BOM protocol
  PACEBO protocol
  PATCO protocol
  PCAV protocol
  PCMF protocol
  P-COMM-B protocol
  PCV regimen
  P-DOCE protocol
  PECC protocol
  perfosfamide Has associated genes Has associated diseases
  PETHEMA ALL-3-97 protocol
  PETHEMA ALL-96 protocol
  phenylketophosphamide
  PM-FAC protocol
  PMitCEBO protocol
  POCC protocol
  POG 8493 protocol
  POMACE protocol
  POMB-ACE-PAV regimen
  POMB-ACE protocol
  POMB-ACE regimen
  Pro-MACE-C-MOPP protocol
  PROMACE-CytaBOM protocol Has associated diseases
  ProMACE-MOPP protocol
  PROMACE protocol
  ProMECE-CytaBOM protocol Has associated diseases
  protocol 8001
  P-VEBEC protocol
  R-14 regimen
  RACOP protocol
  R-CHOP protocol Has associated diseases
  R-FCM protocol
  Rosen's T-10 protocol Has associated diseases
  STAMP-I protocol Has associated diseases
  STAMP V regimen
  Stanford-NCOG protocol
  Stanford University protocol
  St Jude's regimen
  sufosfamide Has associated diseases
  T10 A protocol
  T-6 protocol
  T7 protocol
  TACC protocol
  TAC protocol Has associated diseases
  TCAP protocol
  TCCSG B-8801 protocol
  TCID protocol
  TEC protocol
  THP-COPBLM regimen
  TL-118
  TMC regimen
  TNCF regimen
  TRAMPCOL protocol
  TRAMPCO protocol
  trofosfamide Has associated diseases
  TSOP protocol
  UCH I protocol
  VAB-6 regimen Has associated diseases
  VAB-III protocol
  VAB-IV protocol
  VACAD protocol
  VACA protocol Has associated diseases
  VACIME protocol
  VAC-MAP protocol
  VAC-M protocol
  VACO-B protocol
  VACOP-B protocol Has associated diseases
  VAC protocol Has associated diseases
  VAPAC protocol
  VAP-cyclo protocol Has associated diseases
  VAPEC-B protocol
  VbCFM protocol
  VBCMF protocol
  VCAA protocol
  VCAD regimen
  V-CAM protocol
  VCAV protocol
  VCCP protocol
  VCDP protocol
  VCD protocol
  VCMA protocol
  VCPC protocol
  VCP protocol 2 Has associated diseases
  VCRP protocol
  VCSP protocol
  VDBCP protocol
  VEBEP regimen
  VECABOP protocol
  VEMFAH protocol
  VEMP protocol 1
  VEMP protocol 3
  VEPA-B protocol
  VEPA-L protocol
  VEPA-M protocol
  VEPEMB protocol
  VEP-THP protocol Has associated diseases
  VETOPEC protocol
  VHCP protocol
  VICED protocol
  VICOP-B protocol Has associated diseases
  VinMCP protocol
  VMCP protocol Has associated diseases
  VNCOP-B protocol
  VPCBAE protocol
  VPC protocol
  VQEP protocol