Skip navigation

Chemical Debrisoquin

Name Debrisoquin
CAS Type 1 Name 2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-
Equivalent Terms Debrisoquine | Tendor
CAS Registry Number 1131-64-2
Definition An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Structure Debrisoquin
Top Interacting
Genes
MeSH® ID D003647
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Isoquinolines Has associated genes Has associated diseases Debrisoquin Has associated genes Has associated diseases

Top ↑ Descendants

Debrisoquin Has associated genes Has associated diseases
  3,4-dehydrodebrisoquine
  4-hydroxydebrisoquin
  8-hydroxydebrisoquin
  N-hydroxydebrisoquine