1. |
Deoxyglucose
|
histamine secretion mediated by immunoglobulin
|
Deferoxamine
|
Deoxyglucose inhibits the reaction [Deferoxamine results in increased histamine secretion mediated by immunoglobulin] |
1: Rattus norvegicus |
Peritoneum | Mast Cells |
|
1 |
2. |
Deoxyglucose
|
autophagy
|
|
Deoxyglucose results in increased autophagy |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
3. |
Deoxyglucose
|
autophagy
|
|
Deoxyglucose results in increased autophagy |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
4. |
Deoxyglucose
|
autophagy
|
|
Deoxyglucose results in increased autophagy |
1: Homo sapiens |
Melanocytes | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
5. |
Deoxyglucose
|
cellular response to unfolded protein
|
|
Deoxyglucose results in increased cellular response to unfolded protein |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
1 gene: BAX
|
1 |
6. |
Deoxyglucose
|
cellular response to unfolded protein
|
|
Deoxyglucose results in increased cellular response to unfolded protein |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
1 gene: BAX
|
1 |
7. |
Deoxyglucose
|
cellular response to unfolded protein
|
|
Deoxyglucose results in increased cellular response to unfolded protein |
1: Homo sapiens |
Melanocytes | Cell Line, Tumor |
1 gene: BAX
|
1 |
8. |
Deoxyglucose
|
autophagy
|
cellular response to unfolded protein
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
9. |
Deoxyglucose
|
cellular response to unfolded protein
|
autophagy
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
1 gene: BAX
|
1 |
10. |
Deoxyglucose
|
autophagy
|
cellular response to unfolded protein
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
11. |
Deoxyglucose
|
cellular response to unfolded protein
|
autophagy
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
1 gene: BAX
|
1 |
12. |
Deoxyglucose
|
autophagy
|
cellular response to unfolded protein
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Melanocytes | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
13. |
Deoxyglucose
|
cellular response to unfolded protein
|
autophagy
|
[Deoxyglucose results in increased cellular response to unfolded protein] which results in increased autophagy |
1: Homo sapiens |
Melanocytes | Cell Line, Tumor |
1 gene: BAX
|
1 |
14. |
Deoxyglucose
|
autophagy
|
Oxygen
|
Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
15. |
Deoxyglucose
|
autophagy
|
Oxygen
|
Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
16. |
Deoxyglucose
|
autophagy
|
3-methyladenine
|
3-methyladenine promotes the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
17. |
Deoxyglucose
|
autophagy
|
3-methyladenine
|
3-methyladenine promotes the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
18. |
Deoxyglucose
|
autophagy
|
Sirolimus
|
Sirolimus inhibits the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Pancreas | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
19. |
Deoxyglucose
|
autophagy
|
Sirolimus
|
Sirolimus inhibits the reaction [Deoxyglucose results in increased autophagy] |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
9 genes: ATG3 | ATG4B | ATG7 | BECN1 | MAP1LC3A | MAP1LC3B | SQSTM1 | STK11 | TP53
|
1 |
20. |
Deoxyglucose
|
cell proliferation
|
|
Deoxyglucose results in decreased cell proliferation |
1: Homo sapiens |
Ovary | Cell Line, Tumor |
11 genes: BAX | BCL2 | BCL2L1 | CHRM3 | EGFR | ERBB2 | GCG | MAP2K1 | NPY | RAF1 | TP53
|
1 |
21. |
Deoxyglucose
|
apoptotic process
|
Cisplatin
|
[Deoxyglucose co-treated with Cisplatin] results in increased apoptotic process |
1: Homo sapiens |
Ovary | Cell Line, Tumor |
24 genes: APP | BAX | BCL2 | BCL2L1 | BECN1 | BID | CASP3 | CASP9 | CUL7 | DDIT3 | HMOX1 | HTRA2 | IL1B | MAPK1 | MAPK3 | NFKB1 | PARP1 | RAF1 | RPS6KB1 | SQSTM1 | STK11 | TNF | TP53 | XIAP
|
1 |
22. |
Deoxyglucose
|
apoptotic DNA fragmentation
|
Dexamethasone
|
Deoxyglucose inhibits the reaction [Dexamethasone results in increased apoptotic DNA fragmentation] |
1: Rattus norvegicus |
Thymus Gland |
1 gene: CASP3
|
1 |
23. |
Deoxyglucose
|
histamine secretion mediated by immunoglobulin
|
Diatrizoate
|
Deoxyglucose inhibits the reaction [Diatrizoate results in increased histamine secretion mediated by immunoglobulin] |
1: Homo sapiens |
Basophils | Cells, Cultured |
|
1 |
24. |
Deoxyglucose
|
histamine secretion mediated by immunoglobulin
|
Diatrizoate
|
Deoxyglucose inhibits the reaction [Diatrizoate results in increased histamine secretion mediated by immunoglobulin] |
1: Homo sapiens |
Lung | Mast Cells | Cells, Cultured |
|
1 |
25. |
Deoxyglucose
|
histamine secretion mediated by immunoglobulin
|
Diatrizoate
|
Deoxyglucose inhibits the reaction [Diatrizoate results in increased histamine secretion mediated by immunoglobulin] |
1: Homo sapiens |
Skin | Mast Cells | Cells, Cultured |
|
1 |
26. |
Deoxyglucose
|
glycolytic process
|
|
Deoxyglucose results in decreased glycolytic process |
|
Heart | Cells, Cultured |
|
1 |
27. |
Deoxyglucose
|
regulation of heart rate
|
Halothane
|
Deoxyglucose promotes the reaction [Halothane results in decreased regulation of heart rate] |
|
Heart | Cells, Cultured |
1 gene: PMCH
|
1 |
28. |
Deoxyglucose
|
cell proliferation
|
Oligomycins
| Tamoxifen
|
[Deoxyglucose co-treated with Oligomycins] promotes the reaction [Tamoxifen results in decreased cell proliferation] |
1: Homo sapiens |
Mammary Glands, Human | Cell Line, Tumor |
11 genes: BAX | BCL2 | BCL2L1 | CHRM3 | EGFR | ERBB2 | GCG | MAP2K1 | NPY | RAF1 | TP53
|
1 |
29. |
Deoxyglucose
|
cell chemotaxis
|
|
Deoxyglucose results in increased cell chemotaxis |
1: Homo sapiens |
Granulocytes |
|
1 |
30. |
Deoxyglucose
|
cell chemotaxis
|
Magnesium
|
Magnesium affects the reaction [Deoxyglucose results in increased cell chemotaxis] |
1: Homo sapiens |
Granulocytes |
|
1 |
31. |
Deoxyglucose
|
glycolytic process
|
|
Deoxyglucose results in decreased glycolytic process |
1: Cavia porcellus |
Aorta |
|
1 |
32. |
Deoxyglucose
|
glycolytic process
|
vasodilation
|
[Deoxyglucose results in decreased glycolytic process] which results in increased vasodilation |
1: Cavia porcellus |
Aorta |
|
1 |
33. |
Deoxyglucose
|
vasodilation
|
glycolytic process
|
[Deoxyglucose results in decreased glycolytic process] which results in increased vasodilation |
1: Cavia porcellus |
Aorta |
3 genes: NOS3 | SOD2 | TNF
|
1 |
34. |
Deoxyglucose
|
glycolytic process
|
Tolbutamide
| vasodilation
|
Tolbutamide inhibits the reaction [[Deoxyglucose results in decreased glycolytic process] which results in increased vasodilation] |
1: Cavia porcellus |
Aorta |
|
1 |
35. |
Deoxyglucose
|
vasodilation
|
glycolytic process
| Tolbutamide
|
Tolbutamide inhibits the reaction [[Deoxyglucose results in decreased glycolytic process] which results in increased vasodilation] |
1: Cavia porcellus |
Aorta |
3 genes: NOS3 | SOD2 | TNF
|
1 |
36. |
Deoxyglucose
|
negative regulation of cell growth
|
|
Deoxyglucose results in increased negative regulation of cell growth |
1: Homo sapiens |
Cell Line, Tumor |
5 genes: BCL2 | CDKN1A | PPARG | STK11 | TP53
|
1 |
37. |
Deoxyglucose
|
positive regulation of apoptotic process
|
|
Deoxyglucose results in increased positive regulation of apoptotic process |
1: Homo sapiens |
Lymphocytes |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
38. |
Deoxyglucose
|
positive regulation of apoptotic process
|
|
Deoxyglucose results in increased positive regulation of apoptotic process |
1: Homo sapiens |
Cells, Cultured |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
39. |
Deoxyglucose
|
positive regulation of apoptotic process
|
Cisplatin
|
[Cisplatin co-treated with Deoxyglucose] results in increased positive regulation of apoptotic process |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
40. |
Deoxyglucose
|
positive regulation of apoptotic process
|
Curcumin
|
[Curcumin co-treated with Deoxyglucose] results in increased positive regulation of apoptotic process |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
41. |
Deoxyglucose
|
positive regulation of apoptotic process
|
TNF
|
[TNF protein co-treated with Deoxyglucose] results in increased positive regulation of apoptotic process |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
42. |
Deoxyglucose
|
negative regulation of cAMP-dependent protein kinase activity
|
|
Deoxyglucose results in increased negative regulation of cAMP-dependent protein kinase activity |
1: Homo sapiens |
Cell Line, Tumor |
|
1 |
43. |
Deoxyglucose
|
positive regulation of protein kinase B signaling
|
Arsenic Trioxide
|
Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased positive regulation of protein kinase B signaling] |
1: Homo sapiens |
Cell Line, Tumor |
9 genes: EGFR | ERBB2 | HSP90AA1 | IGF1R | INS | ITGB1 | LEP | MTOR | TNF
|
1 |
44. |
Deoxyglucose
|
positive regulation of apoptotic process
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Deoxyglucose results in increased positive regulation of apoptotic process] |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
45. |
Deoxyglucose
|
positive regulation of apoptotic process
|
U 0126
|
U 0126 promotes the reaction [Deoxyglucose results in increased positive regulation of apoptotic process] |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
46. |
Deoxyglucose
|
positive regulation of apoptotic process
|
triciribine
|
triciribine promotes the reaction [Deoxyglucose results in increased positive regulation of apoptotic process] |
1: Homo sapiens |
Cell Line, Tumor |
20 genes: ATG7 | BAX | BCL2L1 | BID | CASP3 | CASP9 | DDIT3 | GSK3B | HMOX1 | HTRA2 | IL1B | ITGB1 | MMP9 | NOS2 | NOS3 | PPARG | RPS6 | SQSTM1 | TNF | TP53
|
1 |
47. |
Deoxyglucose
|
positive regulation of ERK1 and ERK2 cascade
|
Arsenic Trioxide
|
Arsenic Trioxide inhibits the reaction [Deoxyglucose results in increased positive regulation of ERK1 and ERK2 cascade] |
1: Homo sapiens |
Cell Line, Tumor |
8 genes: APP | EGFR | GCG | IL1B | MAP2K1 | MAPK3 | NPY | TNF
|
1 |
48. |
Deoxyglucose
|
positive regulation of ERK1 and ERK2 cascade
|
PQ 401
|
PQ 401 inhibits the reaction [Deoxyglucose results in increased positive regulation of ERK1 and ERK2 cascade] |
1: Homo sapiens |
Cell Line, Tumor |
8 genes: APP | EGFR | GCG | IL1B | MAP2K1 | MAPK3 | NPY | TNF
|
1 |
49. |
Deoxyglucose
|
positive regulation of protein kinase B signaling
|
PQ 401
|
PQ 401 inhibits the reaction [Deoxyglucose results in increased positive regulation of protein kinase B signaling] |
1: Homo sapiens |
Cell Line, Tumor |
9 genes: EGFR | ERBB2 | HSP90AA1 | IGF1R | INS | ITGB1 | LEP | MTOR | TNF
|
1 |
50. |
Deoxyglucose
|
negative regulation of cAMP-dependent protein kinase activity
|
PQ 401
|
PQ 401 inhibits the reaction [Deoxyglucose results in increased negative regulation of cAMP-dependent protein kinase activity] |
1: Homo sapiens |
Cell Line, Tumor |
|
1 |