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Chemical Diterpenes

1–50 of 2,654 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 12-acetoxyhawtriwaic acid lactone positive regulation of neutrophil chemotaxis Tetradecanoylphorbol Acetate 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased positive regulation of neutrophil chemotaxis] 1: Mus musculus Ear | Neutrophils   1
2. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 | Theophylline Theophylline inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
3. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain] 1: Mus musculus Hindlimb   1
4. 12-acetoxyhawtriwaic acid lactone sensory perception of pain Glyburide | TAC1 Glyburide inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
5. 12-deoxyphorbol-13-isobutyrate-20-acetate vasoconstriction Halothane Halothane inhibits the reaction [12-deoxyphorbol-13-isobutyrate-20-acetate results in increased vasoconstriction] 1: Rattus norvegicus Coronary Vessels   1
6. 12-deoxyphorbol-13-isobutyrate-20-acetate vasoconstriction 12-deoxyphorbol-13-isobutyrate-20-acetate results in increased vasoconstriction 1: Rattus norvegicus Coronary Vessels   1
7. 12-deoxyphorbolphenylacetate-20-acetate activation of protein kinase C activity 12-deoxyphorbolphenylacetate-20-acetate results in increased activation of protein kinase C activity 1: Homo sapiens Lung | Cell Line, Tumor   1
8. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of apoptotic process 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased positive regulation of apoptotic process 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
11 genes: AKT1 | APC | BAD | CASP3 | CASP9 | CTNNB1 | FOXO3 | MMP2 | MMP9 | TP53 | TRP53
1
9. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of filopodium assembly 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of filopodium assembly 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
2 genes: CDC42 | RAC1
1
10. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells 1 gene: PTK2 1
11. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of cell proliferation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of cell proliferation 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
4 genes: AKT1 | BCL2 | CTNNB1 | PTK2
1
12. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of G1/S transition of mitotic cell cycle 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of G1/S transition of mitotic cell cycle 1: Rattus norvegicus Neuroglia | Cell Line, Tumor   1
13. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation PTK2 [16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation] which results in decreased phosphorylation of PTK2 protein 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells 1 gene: PTK2 1
14. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of G1/S transition of mitotic cell cycle 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of G1/S transition of mitotic cell cycle 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells   1
15. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of cell proliferation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of cell proliferation 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
4 genes: AKT1 | BCL2 | CTNNB1 | PTK2
1
16. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation PTK2 [16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation] which results in decreased phosphorylation of PTK2 protein 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: PTK2 1
17. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: PTK2 1
18. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of apoptotic process 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased positive regulation of apoptotic process 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
11 genes: AKT1 | APC | BAD | CASP3 | CASP9 | CTNNB1 | FOXO3 | MMP2 | MMP9 | TP53 | TRP53
1
19. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of filopodium assembly 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of filopodium assembly 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
2 genes: CDC42 | RAC1
1
20. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide positive regulation of NIK/NF-kappaB signaling APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein modified form results in increased positive regulation of NIK/NF-kappaB signaling] 1: Rattus norvegicus PC12 Cells
2 genes: APP | RELA
1
21. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide DNA damage response, detection of DNA damage APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein results in increased DNA damage response, detection of DNA damage] 1: Rattus norvegicus PC12 Cells   1
22. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide cell death APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein modified form results in increased cell death] 1: Rattus norvegicus PC12 Cells   1
23. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of DNA biosynthetic process 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in decreased positive regulation of DNA biosynthetic process 1: Homo sapiens HL-60 Cells   1
24. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of apoptotic DNA fragmentation 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of apoptotic DNA fragmentation 1: Homo sapiens HL-60 Cells   1
25. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell cycle arrest 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell cycle arrest 1: Homo sapiens HL-60 Cells   1
26. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Prostate | Cell Line, Tumor   1
27. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of apoptotic process 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of apoptotic process 1: Homo sapiens HL-60 Cells
2 genes: CASP8 | CASP9
1
28. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Mus musculus Skin | Cell Line, Tumor   1
29. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate negative regulation of mitochondrial membrane potential 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased negative regulation of mitochondrial membrane potential 1: Homo sapiens HL-60 Cells   1
30. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Breast | Cell Line, Tumor   1
31. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Mus musculus Tumor Cells, Cultured   1
32. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Leukocytes, Mononuclear | Cells, Cultured   1
33. 2-O-beta-D-glucopyranosyl-carboxyatractyligenin negative regulation of ATP:ADP antiporter activity 2-O-beta-D-glucopyranosyl-carboxyatractyligenin results in increased negative regulation of ATP:ADP antiporter activity 1: Mus musculus Liver | Mitochondria   1
34. 3-ingenyl angelate release from viral latency 3-ingenyl angelate results in increased release from viral latency 1: Homo sapiens     1
35. 3-ingenyl angelate release from viral latency (+)-JQ1 compound (+)-JQ1 compound promotes the reaction [3-ingenyl angelate results in increased release from viral latency] 1: Homo sapiens     1
36. 3-ingenyl angelate viral process 3-ingenyl angelate results in decreased viral process 1: Homo sapiens T-Lymphocytes | Cells, Cultured   1
37. 3'-p-hydroxypaclitaxel drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 3'-p-hydroxypaclitaxel 1: Homo sapiens Intestine, Large | Microsomes 1 gene: CYP3A4 1
38. 6-hydroxytaxol exogenous drug catabolic process Ethinyl Estradiol | Paclitaxel [[Ethinyl Estradiol results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
39. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Piperonyl Butoxide [[Piperonyl Butoxide results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
40. 6-hydroxytaxol exogenous drug catabolic process Carbon Monoxide | Paclitaxel [[Carbon Monoxide results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
41. 6-hydroxytaxol drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Intestine, Large | Microsomes 1 gene: CYP2C8 1
42. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Testosterone [[Testosterone results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
43. 6-hydroxytaxol exogenous drug catabolic process Midazolam | Paclitaxel [[Midazolam results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
44. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Quercetin [[Quercetin results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
45. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Verapamil [[Verapamil results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
46. abietic acid transepithelial transport abietic acid results in decreased transepithelial transport 1: Homo sapiens Caco-2 Cells   1
47. abietic acid transepithelial transport Digoxin [abietic acid results in decreased transepithelial transport] which results in decreased transport of Digoxin 1: Homo sapiens Caco-2 Cells   1
48. acanthoic acid activation of protein kinase activity AMP-activated protein kinase activity | Ethanol acanthoic acid inhibits the reaction [[Ethanol results in decreased activation of protein kinase activity] which results in decreased AMP-activated protein kinase activity] 1: Homo sapiens Hepatic Stellate Cells | Cell Line, Transformed
2 genes: PRKAA1 | STK11
1
49. acanthoic acid triglyceride homeostasis Ethanol | Triglycerides acanthoic acid inhibits the reaction [[Ethanol results in decreased triglyceride homeostasis] which results in increased abundance of Triglycerides] 1: Mus musculus Serum
3 genes: IL18 | NR1H3 | PPARG
1
50. acanthoic acid lipopolysaccharide transport Ethanol acanthoic acid inhibits the reaction [Ethanol results in increased lipopolysaccharide transport] 1: Mus musculus Serum   1
1–50 of 2,654 results.