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Chemical Diterpenes

1–50 of 2,900 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-deacetylpaclitaxel negative regulation of cell proliferation 10-deacetylpaclitaxel results in increased negative regulation of cell proliferation 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor   1
2. 10-deacetylpaclitaxel response to antineoplastic agent Paclitaxel [Paclitaxel results in decreased response to antineoplastic agent] which results in decreased susceptibility to 10-deacetylpaclitaxel 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor   1
3. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain] 1: Mus musculus Hindlimb   1
4. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 | Theophylline Theophylline inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
5. 12-acetoxyhawtriwaic acid lactone sensory perception of pain Glyburide | TAC1 Glyburide inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
6. 12-acetoxyhawtriwaic acid lactone positive regulation of neutrophil chemotaxis Tetradecanoylphorbol Acetate 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased positive regulation of neutrophil chemotaxis] 1: Mus musculus Ear | Neutrophils   1
7. 12-deoxyphorbol-13-isobutyrate-20-acetate vasoconstriction 12-deoxyphorbol-13-isobutyrate-20-acetate results in increased vasoconstriction 1: Rattus norvegicus Coronary Vessels   1
8. 12-deoxyphorbol-13-isobutyrate-20-acetate vasoconstriction Halothane Halothane inhibits the reaction [12-deoxyphorbol-13-isobutyrate-20-acetate results in increased vasoconstriction] 1: Rattus norvegicus Coronary Vessels   1
9. 12-deoxyphorbolphenylacetate-20-acetate activation of protein kinase C activity 12-deoxyphorbolphenylacetate-20-acetate results in increased activation of protein kinase C activity 1: Homo sapiens Lung | Cell Line, Tumor   1
10. 14-deoxy-11,12-didehydroandrographolide fat cell differentiation 1-Methyl-3-isobutylxanthine | Dexamethasone | INS1 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased fat cell differentiation] 1: Mus musculus 3T3-L1 Cells
5 genes: CCND1 | CEBPB | GSK3B | PPARG | SREBF1
1
11. 14-deoxy-11,12-didehydroandrographolide fat cell differentiation 14-deoxy-11,12-didehydroandrographolide results in decreased fat cell differentiation 1: Mus musculus 3T3-L1 Cells
5 genes: CCND1 | CEBPB | GSK3B | PPARG | SREBF1
1
12. 14-deoxy-11,12-didehydroandrographolide lipid biosynthetic process 1-Methyl-3-isobutylxanthine | Dexamethasone | INS1 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased lipid biosynthetic process] 1: Mus musculus 3T3-L1 Cells
3 genes: FASN | SCD1 | SREBF1
1
13. 14-deoxy-11,12-didehydroandrographolide lipid biosynthetic process 14-deoxy-11,12-didehydroandrographolide results in decreased lipid biosynthetic process 1: Mus musculus 3T3-L1 Cells
3 genes: FASN | SCD1 | SREBF1
1
14. 14-deoxy-11,12-didehydroandrographolide mitotic S phase 1-Methyl-3-isobutylxanthine | Dexamethasone | INS1 14-deoxy-11,12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased mitotic S phase] 1: Mus musculus 3T3-L1 Cells   1
15. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of apoptotic process 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased positive regulation of apoptotic process 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
11 genes: AKT1 | APC | BAD | CASP3 | CASP9 | CTNNB1 | FOXO3 | MMP2 | MMP9 | TP53 | TRP53
1
16. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of cell proliferation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of cell proliferation 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
4 genes: AKT1 | BCL2 | CTNNB1 | PTK2
1
17. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of G1/S transition of mitotic cell cycle 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of G1/S transition of mitotic cell cycle 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells 1 gene: AKT1 1
18. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of filopodium assembly 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of filopodium assembly 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells
2 genes: CDC42 | RAC1
1
19. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells 1 gene: PTK2 1
20. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation PTK2 [16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation] which results in decreased phosphorylation of PTK2 protein 1: Mus musculus Neural Stem Cells | Neuroglia | Cell Line, Tumor | Hybrid Cells 1 gene: PTK2 1
21. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of apoptotic process 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased positive regulation of apoptotic process 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
11 genes: AKT1 | APC | BAD | CASP3 | CASP9 | CTNNB1 | FOXO3 | MMP2 | MMP9 | TP53 | TRP53
1
22. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of cell proliferation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of cell proliferation 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
4 genes: AKT1 | BCL2 | CTNNB1 | PTK2
1
23. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of G1/S transition of mitotic cell cycle 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of G1/S transition of mitotic cell cycle 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: AKT1 1
24. 16-hydroxycleroda-3,13(14)-dien-15,16-olide positive regulation of filopodium assembly 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased positive regulation of filopodium assembly 1: Rattus norvegicus Neuroglia | Cell Line, Tumor
2 genes: CDC42 | RAC1
1
25. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation 16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: PTK2 1
26. 16-hydroxycleroda-3,13(14)-dien-15,16-olide peptidyl-tyrosine autophosphorylation PTK2 [16-hydroxycleroda-3,13(14)-dien-15,16-olide results in decreased peptidyl-tyrosine autophosphorylation] which results in decreased phosphorylation of PTK2 protein 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: PTK2 1
27. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide cell death APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein modified form results in increased cell death] 1: Rattus norvegicus PC12 Cells   1
28. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide DNA damage response, detection of DNA damage APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein results in increased DNA damage response, detection of DNA damage] 1: Rattus norvegicus PC12 Cells   1
29. 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide positive regulation of NIK/NF-kappaB signaling APP 19-hydroxy-1alpha,6-diacetoxy-6,7-seco-ent-kaur-16-en-15-one-7,20-olide inhibits the reaction [APP protein modified form results in increased positive regulation of NIK/NF-kappaB signaling] 1: Rattus norvegicus PC12 Cells
2 genes: APP | RELA
1
30. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Breast | Cell Line, Tumor   1
31. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Prostate | Cell Line, Tumor   1
32. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Mus musculus Skin | Cell Line, Tumor   1
33. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of DNA biosynthetic process 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in decreased positive regulation of DNA biosynthetic process 1: Homo sapiens HL-60 Cells   1
34. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of apoptotic DNA fragmentation 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of apoptotic DNA fragmentation 1: Homo sapiens HL-60 Cells   1
35. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate negative regulation of mitochondrial membrane potential 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased negative regulation of mitochondrial membrane potential 1: Homo sapiens HL-60 Cells   1
36. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell cycle arrest 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell cycle arrest 1: Homo sapiens HL-60 Cells   1
37. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of apoptotic process 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of apoptotic process 1: Homo sapiens HL-60 Cells
2 genes: CASP8 | CASP9
1
38. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Mus musculus Tumor Cells, Cultured   1
39. 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate positive regulation of cell death 1-(acetyloxy)-3,5,6,6a,7,8,9,10-octahydro-10-hydroxy-7,8-dimethyl-7-(3-methylpenta-2,4-dien-1-yl)naphtho(1,8a-c)furan-3,5-diyl dibutanoate results in increased positive regulation of cell death 1: Homo sapiens Leukocytes, Mononuclear | Cells, Cultured   1
40. 2-O-beta-D-glucopyranosyl-carboxyatractyligenin negative regulation of ATP:ADP antiporter activity 2-O-beta-D-glucopyranosyl-carboxyatractyligenin results in increased negative regulation of ATP:ADP antiporter activity 1: Mus musculus Liver | Mitochondria   1
41. 3-ingenyl angelate release from viral latency 3-ingenyl angelate results in increased release from viral latency 1: Homo sapiens     1
42. 3-ingenyl angelate release from viral latency (+)-JQ1 compound (+)-JQ1 compound promotes the reaction [3-ingenyl angelate results in increased release from viral latency] 1: Homo sapiens     1
43. 3-ingenyl angelate viral process 3-ingenyl angelate results in decreased viral process 1: Homo sapiens T-Lymphocytes | Cells, Cultured   1
44. 3'-p-hydroxypaclitaxel drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 3'-p-hydroxypaclitaxel 1: Homo sapiens Intestine, Large | Microsomes 1 gene: CYP3A4 1
45. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Piperonyl Butoxide [[Piperonyl Butoxide results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
46. 6-hydroxytaxol exogenous drug catabolic process Carbon Monoxide | Paclitaxel [[Carbon Monoxide results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
47. 6-hydroxytaxol exogenous drug catabolic process Midazolam | Paclitaxel [[Midazolam results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
48. 6-hydroxytaxol exogenous drug catabolic process Ethinyl Estradiol | Paclitaxel [[Ethinyl Estradiol results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
49. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Quercetin [[Quercetin results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
50. 6-hydroxytaxol exogenous drug catabolic process Paclitaxel | Verapamil [[Verapamil results in decreased exogenous drug catabolic process] which results in decreased hydroxylation of Paclitaxel] which results in decreased chemical synthesis of 6-hydroxytaxol 1: Homo sapiens Liver | Microsomes 1 gene: CYP2C8 1
1–50 of 2,900 results.