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Chemical Epidermal Growth Factor

Name Epidermal Growth Factor
CAS Type 1 Name Epidermal growth factor
Equivalent Terms beta Urogastrone | beta-Urogastrone | EGF | Epidermal Growth Factor-Urogastrone | Growth Factor, Epidermal | Growth Factor-Urogastrone, Epidermal | Human Urinary Gastric Inhibitor | Urogastrone
CAS Registry Number 62229-50-9
Definition A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D004815
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Top ↑ Ancestors

1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Gastrointestinal Hormones Has associated genes Has associated diseases Epidermal Growth Factor
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases EGF Family of Proteins Epidermal Growth Factor

Top ↑ Descendants

Epidermal Growth Factor
  111In-DTPA-human epidermal growth factor
  68Ga-DOTA-hEGF
  biotinyl epidermal growth factor
  biregulin
  CALEB protein, chicken
  E1-INT
  E 6010
  EGF-genistein
  Emr4 protein, mouse
  epidermal growth factor (1-45)
  epidermal growth factor (1-48)
  epidermal growth factor (1-53)
  epidermal growth factor (32-48), Cys-SO3H(33,42)-
  epidermal growth factor (33-42)
  epidermal growth factor-dextran conjugate
  epidermal growth factor--dextran-tyrosine conjugate
  epidermal growth factor-like protein, S(1-5)
  epidermal growth factor, Lys(3)-Tyr(22)-
  epidermal growth factor precursor
  epidermal growth factor-ricin complex
  epidermal growth inhibitors
  fat3 protein, C elegans
  FAT3 protein, human
  Fat3 protein, rat
  Fcy-hEGF fusion protein
  fibropellin protein, sea urchin
  gigantoxin I, Stichodactyla gigantea
  Growth Factors, Combined Defect of
  HmEGFL-1 protein, Herdmania momus
  Humatrix
  Lin-3 protein, C elegans
  Ly64 protein, mouse
  peptabody-EGF
  Pseudomonas exotoxin-epidermal growth factor conjugate
  spi protein, Drosophila
  Tdgf1 protein, mouse
  technetium 99m HYNIC-human epidermal growth factor
  technetium Tc 99m epidermal growth factor
  urogastrone, Lys-beta-