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Chemical Estradiol

Name Estradiol
CAS Type 1 Name Estra-1,3,5(10)-triene-3,17-diol (17beta)-
Equivalent Terms 17 beta Estradiol | 17 beta-Estradiol | 17 beta Oestradiol | 17 beta-Oestradiol | Aerodiol | Estrace | Estraderm TTS | Estradiol, (16 alpha,17 alpha)-Isomer | Estradiol, (16 alpha,17 beta)-Isomer | Estradiol 17 alpha | Estradiol-17 alpha | Estradiol, (17-alpha)-Isomer | Estradiol 17beta | Estradiol 17 beta | Estradiol-17beta | Estradiol-17 beta | Estradiol, (8 alpha,17 beta)-Isomer | Estradiol, (8 alpha,17 beta)-(+-)-Isomer | Estradiol, (9 beta,17 alpha)-Isomer | Estradiol, (9 beta,17 beta)-Isomer | Estradiol Hemihydrate | Estradiol Hemihydrate, (17 alpha)-Isomer | Estradiol, (-)-Isomer | Estradiol, (+-)-Isomer | Estradiol Monohydrate | Estradiol, Monosodium Salt | Estradiol Orion Brand | Estradiol, Sodium Salt | Novartis Pharmaceuticals Brand of Estradiol | Oestradiol | Orion Brand of Estradiol | Ovocyclin | Vivelle
CAS Registry Number 50-28-2
Definition Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
Structure Estradiol
Top Interacting
Genes
MeSH® ID D004958
External Links

Top ↑ Ancestors

1. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Steroids Has associated genes Has associated diseases Estranes Has associated genes Has associated diseases Estrenes Has associated genes Has associated diseases Estradiol Has associated genes Has associated diseases
2. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Hormones Has associated genes Has associated diseases Gonadal Hormones Has associated genes Has associated diseases Gonadal Steroid Hormones Has associated genes Has associated diseases Estradiol Congeners Has associated genes Has associated diseases Estradiol Has associated genes Has associated diseases

Top ↑ Descendants

Estradiol Has associated genes Has associated diseases
  10-hydroxy-17-butoxy-1,3,5(10)-estratrien-3-one
  1,11-ethanoestradiol
  11-(2-fluoroethyl)estradiol
  11-(((4-(5,10,15-triphenylporphyrin-20-yl)phenyl)carbonylamino)butanoyloxy)estradiol
  11 beta-(1-aziridinylmethyl)estradiol
  11beta-bromoacetamidoethoxyphenylE2 estradiol
  11beta-bromoacetamidopentoxyphenylE2 estradiol
  11-beta-chloromethyl-estradiol
  11beta-perfluorohexylestradiol
  11-bromomethyl-estradiol
  11-dehydro-3,17 alpha-estradiol
  11-ethyl-16-fluoroestradiol
  11-ethyl-17-methylestradiol
  11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol Has associated genes Has associated diseases
  11-fluoro-7-(5-(methyl(3-((4,4,5,5,5-pentafluoropentyl)sulfanyl)propyl)amino)pentyl)estra-1,3,5(10)-triene-3,17-diol
  11-fluoro-7-(5-(methyl(7,7,8,8,9,9,10,10,10-nonafluorodecyl)amino)pentyl)estra-1,3,5(10)-triene-3,17-diol
  11-methoxy-16-fluoroestradiol
  11-methoxy-16-iodoestradiol
  11-methoxy-4,16-difluoroestradiol
  1-(2-chloroethyl)-1-nitrosocarbamoylalanine estradiol-17-ester
  12-oxo-9(11)-dehydroestradiol
  1,3,5(10)-estratriene-3,17beta-diol 17-hemisuccinate
  1,3,5-estratriene-3,17beta-diol 17-hemisuccinate
  14,15-methylene estradiol
  14-hydroxyestradiol
  15 alpha-hydroxyestradiol
  15 alpha-hydroxyestradiol 3-sulfate
  16 alpha-bromo-11 beta-methoxy-17 beta-estradiol
  16 alpha-bromo-17 beta-estradiol Has associated genes Has associated diseases
  16 alpha-bromoacetoxyestradiol-3-methyl ether
  16 alpha-cyanoestradiol 3-methyl ether
  16 alpha-iodoestradiol Has associated genes Has associated diseases
  16beta-aminopropyl estradiol
  16 beta-ethylestradiol-17 beta
  16-fluoroestradiol
  16-fluoroestradiol-3,17-disulfamate
  16-formylestradiol
  16-hydroxymethylestra-1,3,5(10)-triene-3,17-diol
  16-iodo-11-methoxyestradiol
  16-ketoestradiol
  16-methoxyestradiol
  16-methylene estradiol
  16-oxoestradiol 3-sulfate
  17-(2-iodovinyl)-11-chloromethylestradiol
  17-(3-((2-phenylquinolin-4-yl)carbonyloxy)propynyl)estradiol
  17 alpha-cyanomethylestradiol 3-methyl ether
  17 alpha-estradiol-3-galacturonide
  17 alpha-ethyl-5 xi-estrane-3 xi,17 beta-diol
  17 alpha-iodovinyl-11 beta-methoxyestradiol
  17 alpha-iodovinylestradiol
  17 alpha-n-butylestradiol-3-cyclopentyl ether
  17-amino-1,3,5(10)estratrien-3-ol
  17-benzylestradiol 3-O-sulfamate
  17 beta-(arylazido-beta-alanine)estradiol-3-methyl ether
  17 beta-estradiol 3-tetrahydropyranyl ether
  17 beta-estradiol hemisuccinate
  17beta-estradiol platinum(II)
  17-bromoacetamidopropylestradiol
  17-butoxy-1,3,5(10)-estratrien-3-ol
  17-desoxyestradiol Has associated genes Has associated diseases
  17-dioxanylestradiol
  17-estradiol cyclooctyl acetate
  17-estradiol hydroxypropylcyclodextrin complex
  17-ethylestradiol
  17-ethynyl-16-fluoroestradiol
  17-glucuronosylestradiol
  17-hydroxy-3-methoxy-14,15-methylen-estra-1,3,5(a)-trien
  17-hydroxyestra-1,3,5(10)-trien-3-ylmethanesulfonic acid
  17-iodoacetoxyestradiol-3-sulfate
  17-iodovinyl-11-ethylestradiol
  17-iodovinyl-11-methoxyestradiol-3-methyl ether
  17-iodovinylestradiol-3-methyl ether
  17-methylestradiol
  17-(N,N,-dimethylhydrazinocarbonyloxy)estra-1,3,5(10)-trien-3-ol
  17-(tert-butylbenzyl)estradiol 3-O-sulfamate
  18-fluoro-17-estradiol
  18-methylestradiol-3-methyl ether
  1a-(4-(3-benzoyloxy-1,3,5(10)-estratrien-17-yloxycarbonyl)butyryl)mitomycin C
  1a-(4-(3-hydroxy-1,3,5(10)-estratrien-17-yloxycarbonyl)butyryl)mitomycin C
  1-bromoestradiol
  1-chloroestradiol
  1-fluoroestradiol
  21-(2-(N,N-dimethylamino)ethyl)oxy-7a-methyl-19-norpregna-1,3,5(10),17(20)-tetraen-3-ol
  21-((4-amino)phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17-diol
  2,14-dihydroxyestradiol
  21-chloro-21-iodovinylestradiol
  21-iodo-11-nitrato-19-norpregna-1,3,5(10),20-tetraene-3,17-diol
  2,4-dibromo-17-acetylestradiol
  2,4-dibromo-17-estradiol
  2,4-dibromo-17-iodovinylestradiol
  2,4-dibromoestra-1,3,5(10),6-tetraene-3,17-diol diacetate
  2,4-dichloro-17-iodovinylestradiol
  2,4-dimethyl-17-iodovinylestradiol
  2-chloroestradiol
  2-ethoxyestradiol Has associated diseases
  2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol
  2-ethylestradiol sulfamate Has associated diseases
  2-ethyloestradiol-bis-sulfamate Has associated diseases
  2-fluoro-4-hydroxyestradiol
  2-fluoroestradiol
  2-fluoroethoxyestradiol
  2-fluoropropanoxyestradiol
  2-hydroxy-3-deoxyestradiol
  2-hydroxy-3-methoxyestradiol Has associated genes Has associated diseases
  2-hydroxy-4-glutathion-S-yl-17 beta-estradiol
  2-hydroxyestradiol Has associated genes Has associated diseases
  2-hydroxyestradiol-17-glucuronide
  2-hydroxyestradiol 17-sulfate
  2-hydroxyestradiol-2,3-dibenzoate
  2-hydroxyestradiol 2,3-methylene ether
  2-iodoestradiol
  2-methoxy-17-cyanomethylestra-1,3,5(10)-trien-3-ol
  2-methoxy-7alpha-methylestradiol
  2-methoxyestradiol Has associated genes Has associated diseases
  2-methoxyestradiol 17-phosphate
  2-methoxyestradiol-3,17-bis-O,O-sulfamate Has associated genes Has associated diseases
  2-methoxyestradiol 3,17-diphosphate
  2-methoxyestradiol 3-phosphate
  2-methoxyestradiol sulfamate
  2-methoxymethylestradiol
  2-methoxyoestradiol Has associated diseases
  2-methylestradiol
  3,17-diacetoxyestra-1,3,5(10)-trien-2-carboxylic acid
  3,17-dihydroxyestra-1,3,5(10)-trien-15-yl-2'-acetamido-2'-deoxyglucopyranoside
  3,17-dihydroxyestra-1,3,5(10)-triene 6-N-(epsilon-biotinyl)caproamide
  3-(2-iodobenzoyl)estradiol
  3-(3',17'-dihydroxyestra-1',3',5'(10')-trien-16'-methyl)benzamide
  3-acetyl-estradiol
  3-deoxyestradiol 17-sulfate
  3-methoxyestradiol
  3-propoxy-17-methoxyestradiol
  4,6 beta-ethanoestradiol
  4-amino-N-fluorescein isothiocyanate-17-estradiol
  4-azidoestradiol
  4-chloroestradiol
  4-fluoro-11-methoxy-16-fluoroestradiol
  4-fluoro-2-hydroxyestradiol
  4-fluoroestradiol
  4-hydroxy-2-methylestradiol
  4-hydroxyestradiol 17-sulfate
  4-hydroxyestradiol-2-N-acetylcysteine
  4-hydroxyestradiol-3,4-dibenzoate
  4-mercuriestradiol
  4-methoxyestradiol Has associated genes Has associated diseases
  4-methylestradiol
  6-((2'-aminoethyl)carboxamidoethyl)estradiol
  6-(5-azido-2-nitrobenzoyl)amidoestradiol
  6-aminoestradiol
  6-hydroxyestradiol 17-sulfate
  6-iodo-1,3,5(10),6-tetraene-3,17 beta-diol
  6-ketoestradiol
  6-methoxy-7-bromoestradiol
  7-(11-(4-iodophenoxy)undecyl)-17-estradiol
  7-(3'-carboxypropyl)estradiol
  7-(4,8,12-trimethyltridecyl)estra-1,3,5-trien-3,17-diol
  7-(5-(4,4-difluoro-5,7-dimethyl-4-bora-3,4-diaza-3-indacenepropionyl)aminopentyl)estradiol
  7-(5-fluoropentyl)estradiol
  7alpha-methyl ethinylestradiol
  7-hydroxyestradiol 17-sulfate
  7-thiophenylestradiol
  abeo-estradiol
  alfatradiol
  benzo(d,e)estra-1,3,5(10)-triene-3,17 beta-diol 17-acetate
  bestrabucil Has associated diseases
  bone-seeking estrogen
  caprovestrol
  CD-37 compound
  CH 4893237
  cis-diamino(2-(4-(17alpha-ethynylestradiolyl)-benzoylamino)-malonato)platinum
  cis-dichloro(N-(4-(17alpha-ethynylestradiolyl)-benzyl)-ethylenediamine)platinum
  CycloProvera Has associated genes Has associated diseases
  Cyklabil
  deladroxate
  delta(9(11))-dehydro-17beta-estradiol
  diestradiol
  divina
  EBCO
  EM 139
  EM-1745
  EM-1913
  estra-1,3,5(10),6-tetraene-3,17-diol
  estra-5(10),6,8-triene-3,17-diol
  estra-5(10),7-diene-3,17-diol
  estradiol-16 Has associated genes Has associated diseases
  estradiol 17-acetate
  estradiol 17-acetylglucosaminide
  estradiol-17-arachidonate
  estradiol-17-benzoate
  estradiol-17beta 3-carboranylmethyl ether
  estradiol-17-beta-3-hemisuccinyl-bovine serum albumin
  estradiol-17 beta-3-methyl ether Has associated genes Has associated diseases
  estradiol-17 beta-benzoate Has associated genes Has associated diseases
  estradiol 17 beta-cypionate Has associated genes Has associated diseases
  estradiol-17 beta-decanoate
  estradiol-17 beta-glucuronide Has associated genes Has associated diseases
  estradiol-17 beta-succinyl-bovine serum albumin
  estradiol 17-butyrate
  estradiol 17-dihydrotrigonelline
  estradiol-17-glucosiduronate-(C-6)-bovine serum albumin conjugate
  estradiol 17-hemisuccinate-bovine serum albumin-fluorescein isothiocyanate
  estradiol-17-O-hemiglutarate
  estradiol 17-palmitate
  estradiol-17-phenylpropionate
  estradiol-17-stearate
  estradiol 17-sulfate
  estradiol 17-undecanoate
  estradiol-2,3-O-quinone
  estradiol-3,17-diacetate
  estradiol 3,17-disulfate Has associated genes Has associated diseases
  estradiol-3,4-quinone Has associated genes Has associated diseases
  estradiol 3-benzoate Has associated genes Has associated diseases
  estradiol-3-benzoate-17-n-butyrate
  estradiol-3-dansylate
  estradiol-3-glucoside
  estradiol-3-glucuronide Has associated genes Has associated diseases
  estradiol-3-O-carboxymethyl ether
  estradiol-3-O-sulfamate
  estradiol 3-propyl ether
  estradiol-3-sulfate
  estradiol-3-trimethylsilyl ether-17-heptafluorobutyrate
  estradiol-3-xyloside
  estradiol-6-(O-carboxymethyl)oxime
  estradiol 6-O-carboxymethyloxime-bovine serum albumin-fluorescein isothiocyanate
  estradiol-6-oxime
  estradiol benzoate, estradiol dienanthate, testosterone enantate drug combination
  estradiol benzoate, estradiol phenylpropionate, testosterone phenylpropionate, testosterone propionate drug combination
  estradiol benzoate, progesterone drug combination
  estradiol benzoate, testosterone propionate drug combination
  estradiol bis(tert-butyldimethylsilyl)ether
  estradiol-bovine serum albumin Has associated genes Has associated diseases
  estradiol-bovine serum albumin-biotin
  estradiol dienanthate
  estradiol dipropionate Has associated genes Has associated diseases
  estradiol-drospirenone combination Has associated diseases
  estradiol (E(2))-Asp-hexapeptide conjugate
  estradiol enanthate
  estradiol, estriol drug combination
  estradiol hexahydrobenzoate
  estradiol nitrate
  estradiol, norethindrone drug combination Has associated genes Has associated diseases
  estradiol, norethisterone, testosterone drug combination
  estradiol ruthenocenecarboxylate
  estradiol sulfate Has associated genes
  estradiol valerate Has associated genes Has associated diseases
  estradiol valerate, cyproterone acetate drug combination
  estradiol valerate-dienogest Has associated genes Has associated diseases
  estradiol Valerate, dienogest drug combination
  estradiol valerate, testosterone enantate drug combination
View node Estramustine Has associated genes Has associated diseases
  estrapronicate
  estredox
  estrynamine
  ethyl (3,17-dihydroxyestra-1,3,5(10)-triene-11-yl)acetate
  ethylenestradiol
  etrosteron
  femoston
  fulvestrant Has associated genes Has associated diseases
  gravibinian
  Gynodian
  hexestrol-3',4'-quinone
  HMR 3339 Has associated genes Has associated diseases
  homoestradiol
  hormonin
  ICI 164384 Has associated genes Has associated diseases
  Implix
  Injectable No. 1
  J811 scavestrogen
  J861 scavestrogen
  klimaxil
  klimonorm
  KW 2581 Has associated diseases
  LE(2)
  Lunelle
  Malun 25
  methyl (3,17-dihydroxyestra-1,3,5(10)-triene-11-yl)acetate
  N(2)-(estradiol-6-yl)-2'-deoxyguanosine
  N-butyl-2-(5-(4-(3,17-dihydroxyestra-1,3,5(10)-trien-11-yl)phenoxy)pentylthio)-N-methylacetamide
  N-butyl-N-methyl-7-(3',17'beta-dihydroxy-1',3',5'(10')-estratriene-6'beta-yl)-7-thiaheptanamide
  N-butyl,N-methyl-8-(3',17'-dihydroxyestra-1',3',5'(10')-trien-17'-yl)-7-octynamide
  netagen
  N-fluoresceino-N'(17 beta-(estradiol-hemisuccinamide)-ethyl)-thiourea
  Org 369-2
  O-(saccharinylmethyl)estradiol
  oxabolone cypionate
  Phillips Corona Ointment
  polyestradiol
  polyestradiol phosphate Has associated genes Has associated diseases
  primosiston
  promestriene
  Revalor
  RU 39411
  RU 45144
  RU 58668 Has associated genes Has associated diseases
  SHD 386L
  Syncro-Mate B
  technetium Tc 99m 3,17-estradiolyl propyl 1,4,8,11-tetraazacyclotetradecanyl-1-(4-methylbenzoic acid) ester
  tetrakis(3,17-diacetoxyestra-1,3,5(10)-trien-2-carboxylato)dicopper(II)
  trisequence
  Trisequens
  trophobolen
  TS 108 Has associated genes Has associated diseases
  ZK 115194
  ZK 136295
  ZK253 Has associated diseases
  ZK703 Has associated diseases
  ZYC 5