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Chemical Etoposide

Name Etoposide
CAS Type 1 Name Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
Equivalent Terms alpha-D-Glucopyranosyl Isomer Etoposide | Baxter Brand of Etoposide | Baxter Oncology Brand of Etoposide | Bristol Myers Brand of Etoposide | Bristol-Myers Brand of Etoposide | Bristol Myers Squibb Brand of Etoposide | Bristol-Myers Squibb Brand of Etoposide | Celltop | Demethyl Epipodophyllotoxin Ethylidine Glucoside | Eposide | Eposin | Eto GRY | Eto-GRY | Etomedac | Etopos | Etoposide, (5a alpha,9 alpha)-Isomer | Etoposide, (5a alpha)-Isomer | Etoposide, (5S)-Isomer | Etoposide, alpha D Glucopyranosyl Isomer | Etoposide, alpha-D-Glucopyranosyl Isomer | Etoposide Pierre Fabre | Etoposide Teva | Etoposido Ferrer Farma | Exitop | Ferrer Brand of Etoposide | Gry Brand of Etoposide | Lastet | Lemery Brand of Etoposide | Medac Brand of Etoposide | Novartis Brand of Etoposide | NSC141540 | NSC 141540 | NSC-141540 | Onkoposid | Onkoworks Brand of Etoposide | Pharmachemie Brand of Etoposide | Pierre Fabre Brand of Etoposide | Prasfarma Brand of Etoposide | Riboposid | ribosepharm Brand of Etoposide | Sanfer Brand of Etoposide | Tedec Meiji Brand of Etoposide | Teva Brand of Etoposide | Toposar | Vepesid | Vépéside Sandoz | Vépéside-Sandoz | VP16 | VP 16 | VP-16 | VP 16213 | VP 16 213 | VP 16-213
CAS Registry Number 33419-42-0
Definition A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
Structure Etoposide
Top Interacting
Genes
MeSH® ID D005047
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Cyclic Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Polycyclic Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Naphthalenes Has associated genes Has associated diseases Has associated exposure references Tetrahydronaphthalenes Has associated genes Has associated diseases Has associated exposure references Podophyllotoxin Has associated genes Has associated diseases Etoposide Has associated genes Has associated diseases
2. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Polycyclic Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Naphthalenes Has associated genes Has associated diseases Has associated exposure references Tetrahydronaphthalenes Has associated genes Has associated diseases Has associated exposure references Podophyllotoxin Has associated genes Has associated diseases Etoposide Has associated genes Has associated diseases
3. ChemicalsCarbohydrates Has associated genes Has associated diseases Has associated exposure references Glycosides Has associated genes Has associated diseases Has associated exposure references Glucosides Has associated genes Has associated diseases Etoposide Has associated genes Has associated diseases

Top ↑ Descendants

Etoposide Has associated genes Has associated diseases
  2'-chloroetoposide
  3',4'-dihydroxyetoposide
  4'-ester etoposide
  4'-O-demethyl-4-((2''-(dimethylamino)ethyl)amino)-4-desoxypodophyllotoxin
  4'-O-demethyl-4-((3''-(dimethylamino)propyl)amino)-4-desoxypodophyllotoxin
  4'-O-demethyl-4-((4''-(1''-benzylpiperidinyl))amino)-4-desoxypodophyllotoxin
  4'-O-demethyl-4-(4''-(benzimidazol-2''-yl)anilino)-4-desoxypodophyllotoxin
  ABEP protocol 1
  ABEP protocol 2
  AB-triple V protocol
  ACE protocol 1 Has associated diseases
  ACE protocol 2
  AclBEP protocol
  ACOP-E protocol
  AEP protocol
  ALL-85 protocol
  AML91 protocol
  ANG 1009
  ANLL91 protocol
  AOPE protocol
  A-TRIPLE-V protocol
  AVI protocol Has associated diseases
  AVPP protocol
  B-8801 protocol
  BACOD-VP16 protocol
  BAEC protocol Has associated genes Has associated diseases
  BAVC protocol
  BCHE protocol
  BEACOPP protocol Has associated genes Has associated diseases
  BEAM regimen Has associated diseases
  BECALM protocol
  BEMOP-CA protocol
  BEMP protocol
  BEM protocol
  BEP protocol Has associated genes Has associated diseases
  BEPV protocol
  BF-9 protocol
  BMVC protocol
  BODIPY-etoposide
  BOMES protocol
  BOP-CISCA-POMB-ACE regimen Has associated diseases
  BOVAPEC protocol
  B-triple-V protocol
  BuCEt protocol
  CAE-P protocol
  CAEVM protocol
  CAMBO-VIP protocol
  CAMEO protocol
  CAPE-PALE protocol
  CARE protocol
  CAV-HEM protocol
  CAVP protocol
  CAV regimen
  CBV protocol Has associated genes Has associated diseases
  CCAVP16 protocol
  CCE protocol Has associated diseases
  CEA protocol Has associated diseases
  CE-AVN protocol
  CEBA combination
  CE-CAP protocol
  CEC protocol
  CEE protocol
  CEMP protocol
  CEO-PE protocol
  CEOP-IMVP-Dexa regimen
  CEPP protocol
  CEP protocol
  CEVAD protocol
  CEVD protocol
  CEVP protocol
  CEV regimen
  CHASE protocol
  CHEP protocol
  CHOEP protocol Has associated diseases
  CHOP-V-MMV protocol
  CHOP-VP16 protocol
  CisEBP protocol
  CMED protocol
  CMV regimen
  COCE protocol
  COMET-A protocol
  COMPE protocol
  COMP-VAN protocol
  COMVP protocol
  COPEP protocol
  COPE regimen Has associated diseases
  CPVP protocol
  CTEC protocol
  CTR III protocol
  CVACE protocol
  DAV regimen Has associated diseases
  D-CECaT regimen
  DCEP protocol Has associated diseases
  DCTER protocol
  DEB-M protocol
  Dexa-BEAM protocol Has associated diseases
  DICE protocol Has associated diseases
  DIZE protocol
  DT-PACE protocol Has associated diseases
  DT PACE regimen
  DVP (cisplatin)
  EACB protocol
  EAC regimen
  EAP-II protocol
  EAP protocol
  ECAPP protocol
  ECBC protocol
  ECHO protocol Has associated diseases
  EC regimen Has associated diseases
  EC regimen 2
  EDAP regimen Has associated diseases
  EEPFL protocol
  EEP protocol
  EFP protocol Has associated diseases
  ELETOP protocol
  ELFE regimen
  ELF protocol Has associated diseases
  EMA-CO protocol
  EMACO protocol
  EMLP protocol
  ENSG 3C protocol
  EORTC GIMEMA AML-10 protocol
  EORTC GIMEMA AML-13 protocol
  EPOCH protocol Has associated diseases
  EP-OMB protocol
  EPO protocol
  EpPt-OMB protocol
  EPVP protocol
  ESAP protocol Has associated diseases
  ESA protocol
  ESHAP regimen Has associated diseases
  ESHAP regimen, modified
  ETI protocol
  etoposide 4'-sulfate
  etoposide glucuronide
  etoposide phosphate Has associated genes Has associated diseases
  EVAP protocol Has associated diseases
  EVAP regimen
  EVA regimen Has associated diseases
  EVI protocol
  EV protocol
  FAPEL protocol
  FEPA protocol
  FEP protocol
  FLEP regimen Has associated diseases
  GEMIA protocol
  G-IDEA protocol
  GIMEMA ALL 0394
  GL 331
  HD-CEP regimen
  HD-CNV protocol
  HM 89 protocol
  HM 91 protocol
  HOPE-Bleo protocol
  HR-3 protocol
  ICBV regimen
  ICE protocol 1 Has associated diseases
  ICE protocol 2
  ICE protocol 3 Has associated diseases
  ICE protocol 4 Has associated diseases
  ICE protocol 5 Has associated diseases
  ICE protocol 6 Has associated diseases
  IE protocol Has associated diseases
  IEVM protocol
  IEV protocol
  IIVP-16
  IMEP protocol
  IMVP-16 protocol Has associated diseases
  IVAC protocol Has associated diseases
  IVAD protocol
  IVAM regimen
  IVEP protocol
  JEB protocol
  JET protocol Has associated diseases
  LEAMP protocol
  LEMP protocol
  LMB89 protocol
  LPA97R protocol
  LSG15 regimen
  MAC-VD protocol
  MAE protocol
  MAPECO protocol
  MAV protocol Has associated diseases
  MAZE protocol
  MB-triple V protocol
  MCP 842 regimen
  MEA protocol
  MEA regimen
  MECA protocol
  MECCA protocol
  MECHOP-BM protocol
  MECP protocol
  MEC regimen Has associated diseases
  MEPH protocol
  MEPP protocol
  MIME protocol
  MINE-BOP protocol Has associated diseases
  MINE-ESHAP protocol
  MINE protocol Has associated diseases
  MINE regimen Has associated diseases
  MIZE protocol
  MLL-93 protocol
  MME protocol
  MOPLACE protocol
  MOPLEC protocol
  MPEMi protocol
  MPEpiE protocol
  MRC AML 10 protocol Has associated diseases
  MV2 protocol
  MVT protocol
  NEO-MACOP-B protocol
  NOPE protocol Has associated diseases
  NPF-etoposide
  OMEC regimen
  OPEC OJEC protocol Has associated diseases
  OPEC protocol 2
  OPEN protocol
  PABlOE protocol
  PACE-BOM protocol
  PACEBO protocol
  PACET protocol
  PAE protocol
  PAME protocol
  PAVE protocol 2 Has associated diseases
  PAVI protocol
  PAV-M protocol
  P-DOCE protocol
  PEA-M regimen
  PEA regimen
  PEEC-M protocol
  PEEC protocol Has associated diseases
  PEM protocol
  PEN protocol
  PEP protocol
  PETHEMA ALL-3-97 protocol
  PET protocol
  PEV-B protocol
  PMitCEBO protocol
  PMUE protocol
  PMUE protocol 2
  POEM-Bleo protocol
  POG-8498 protocol
  POMACE protocol
  POMB-ACE-PAV regimen
  POMB-ACE protocol
  POMB-ACE regimen
  Pro-MACE-C-MOPP protocol
  PROMACE-CytaBOM protocol Has associated diseases
  ProMACE-MOPP protocol
  PROMACE protocol
  ProMECE-CytaBOM protocol Has associated diseases
  P-VEBEC protocol
  PVeBV protocol
  PVP protocol 3
  RIME regimen
  Stanford V protocol Has associated diseases
  T-8801 protocol
  TCCSG B-8801 protocol
  TEC protocol
  TEMP protocol
  TOP 53
  TOP 53 glucuronide
  VABE protocol
  VAC combination
  VACIME protocol
  VACO-B protocol
  VACOP-B protocol Has associated diseases
  VAD combination Has associated diseases
  VAE protocol
  VAPEC-B protocol
  VAPE protocol
  VATA protocol
  VAV protocol
  VBVP protocol Has associated diseases
  V-CAM protocol
  VCAV protocol
  VEBEP regimen
  VECABOP protocol
  VEEP regimen Has associated diseases
  VEP combination
  VEP protocol
  VETOPEC protocol
  VICED protocol
  VIC-E protocol
  VICOP-B protocol Has associated diseases
  VIM-Bleo protocol
  VIMB protocol
  VIM-D protocol
  VIP-B protocol
  VIP-E protocol Has associated diseases
  VIPP-BM protocol
  VIP-VB protocol
  VlhP protocol
  VMF regimen
  VMP regimen
  VMV protocol
  VNCOP-B protocol
  VP-BBML protocol
  VPCBAE protocol
  VPC regimen
  VP-P protocol
  VPQ compound
  vvp protocol