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Chemical Fatty Acids

These are exposure studies associated with the chemical and all of its children.

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1–50 of 102 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Vermeulen R, et al. (2004). Benzene and toluene exposures were determined in part by the degree of contact with glues, the benzene and toluene content of each glue, air movement and ventilation patterns. 1,1,1-trichloroethane | 2,2,4-trimethylpentane | 3-xylene | 4-xylene | Acetone | Benzene | chlorobenzene | ethyl acetate | ethylbenzene | ethylene dichloride | Heptanes | Hexanes | Methylene Chloride | methylethyl ketone | methyl isobutyl ketone | octane | pentane | Toluene Workers China air, indoor 1,1,1-trichloroethane | 2,2,4-trimethylpentane | 3-xylene | 4-xylene | Acetone | Benzene | chlorobenzene | ethyl acetate | ethylbenzene | ethylene dichloride | Heptanes | Hexanes | Methylene Chloride | methylethyl ketone | methyl isobutyl ketone | octane | pentane | Toluene Details
2. Varlet V, et al. (2015). We analyzed 42 models from 14 brands of refill liquids for e-cigarettes for the presence of micro-organisms, diethylene glycol, ethylene glycol, hydrocarbons, ethanol, aldehydes, tobacco-specific nitrosamines, and solvents. 1,1-diethoxyethane | 1,3-butadiene | 1-Butanol | 1-Propanol | 2-butenal | 2-methylbenzaldehyde | 3-methylbenzaldehyde | 4-cymene | 4-methylbenzaldehyde | Acetaldehyde | Acetoin | Acetone | Acrolein | alpha-pinene | benzaldehyde | beta-pinene | butyraldehyde | Cyclohexane | Diacetyl | diethylene glycol | Ethanol | ethyl acetate | Ethylene Glycol | ethyl propionate | Formaldehyde | gamma-terpinene | Hydrocarbons | isobutyl acetate | isovalerylaldehyde | Limonene | n-hexanal | Nitrosamines | pentanal | propionaldehyde Switzerland e-cigarette, liquid 1,1-diethoxyethane | 1,3-butadiene | 1-Butanol | 1-Propanol | 2-butenal | 2-methylbenzaldehyde | 3-methylbenzaldehyde | 4-cymene | 4-methylbenzaldehyde | Acetaldehyde | Acetoin | Acetone | Acrolein | alpha-pinene | benzaldehyde | beta-pinene | butyraldehyde | Cyclohexane | Diacetyl | diethylene glycol | Ethanol | ethyl acetate | Ethylene Glycol | ethyl propionate | Formaldehyde | gamma-terpinene | Hydrocarbons | isobutyl acetate | isovalerylaldehyde | Limonene | n-hexanal | Nitrosamines | pentanal | propionaldehyde Details
3. Aszyk J, et al. (2017). A gas chromatography-electron ionization-mass spectometry method was developed and validated for the simultaneous determination of 46 commonly used flavour additives in e-liquids. 1-hexanol | 3,4-dihydrocoumarin | 3-hexen-1-ol | 4-Butyrolactone | alpha-terpineol | anisyl acetate | benzaldehyde | benzyl acetate | Benzyl Alcohol | citronellol | decan-4-olide | decanaldehyde | ethyl hexanoate | Eugenol | Furaldehyde | furfuryl alcohol | isoamyl acetate | Limonene | linalyl acetate | methyl acetate | n-pentanol | raspberry ketone Poland e-cigarette, liquid 1-hexanol | 3,4-dihydrocoumarin | 3-hexen-1-ol | 4-Butyrolactone | alpha-terpineol | anisyl acetate | benzaldehyde | benzyl acetate | Benzyl Alcohol | citronellol | decan-4-olide | decanaldehyde | ethyl hexanoate | Eugenol | Furaldehyde | furfuryl alcohol | isoamyl acetate | Limonene | linalyl acetate | methyl acetate | n-pentanol | raspberry ketone Details
4. Woodruff TJ, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Pregnant females | Study subjects United States blood | serum | urine 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Details
5. Robledo CA, et al. (2015). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Preconceptional maternal and paternal concentrations of several persistent organic pollutants were associated with statistically significant differences in birth size among offspring. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hexachlorocyclohexane | hexadecafluoro-nonanoic acid | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Infants or newborns | Mothers | Study subjects United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hexachlorocyclohexane | hexadecafluoro-nonanoic acid | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Details Prenatal Exposure Delayed Effects | developmental growth | head development
6. Braun JM, et al. (2014). Health Outcomes and Measures of the Environment (HOME) | National Health and Nutrition Examination Survey (NHANES) We used a semi-Bayesian hierarchical regression model to estimate associations between prenatal blood or urine concentrations of 52 suspected endocrine disrupting chemicals and autistic behaviors at 4 and 5 years of age in a prospective birth cohort of 175 mothers and their children. socioeconomic status | tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Children | Pregnant females | Study subjects United States serum | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2-ethyl-5-carboxypentyl phthalate | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Details Autism Spectrum Disorder
7. Robinson O, et al. (2015). INfancia y Medio Ambiente (INMA) Project In summary, the correlation analysis presented here of multiple environmental exposures among pregnant women provide a first picture of the structure of the exposome during the crucial in utero period. 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Pregnant females Spain air | blood, cord | colostrum | serum | urine | water 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Details
8. Béranger R, et al. (2016). PELAGIE Prenatal urine concentrations of two glycol ethers metabolites were associated with lower Wechsler Intelligence Scale for Children IV Verbal Comprehension Index scores and Developmental Neuropsychological Assessment Design Copying subscale scores, respectively, at age six. 2-(2-methoxyethoxy)ethanol | carbitol | Ethylene Glycols | n-butoxyacetic acid | phenoxyethanol Children | Pregnant females France urine carbitol | ethoxyacetic acid | methoxyacetic acid | n-butoxyacetic acid | phenoxyacetic acid Details cognition | visual learning
9. Lenters V, et al. (2016). In this study of mother-newborn pairs from Greenland, Poland, and Ukraine, prenatal exposure to a diethylhexyl phthalate metabolite (mono(2-ethyl-5-hydroxyhexyl) phthalate), perfluorooctanoic acid, and dichlorodiphenyldichloroethylene were independently associated with lower birth weight in term newborns. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Hydrocarbons, Chlorinated | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | phthalic acid Pregnant females Greenland|Poland|
Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | 2-ethyl-5-carboxypentyl phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | diisononyl phthalate | Hydrocarbons, Chlorinated | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono(carboxy-isooctyl)phthalate | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | phthalic acid Details Prenatal Exposure Delayed Effects
10. Hoppin JA, et al. (2017). Agricultural Health Study (AHS) We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | bentazone | Carbaryl | Chlorpyrifos | clomazone | clopyralid | cyfluthrin | Dicamba | Dimethoate | Disulfoton | fenoxaprop ethyl | fluazifop-butyl | glyphosate | Herbicides | imazaquin | Insecticides | Malathion | mesotrione | metolachlor | N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide | nicosulfuron | Permethrin | Petroleum | Picloram | Pyrethrins | Rodenticides | Simazine | triclopyr | Trifluralin | Warfarin Workers United States Details Respiratory Sounds | Rhinitis, Allergic
11. Louis GM, et al. (2015). Longitudinal Investigation of Fertility and the Environment Study (LIFE) We found that select perfluorinated chemicals at environmentally relevant concentrations were associated with differences in sperm head, morphology, and DNA characteristics, including differences indicative of higher and lower semen quality. 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Study subjects United States serum 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Details spermatogenesis
12. Lyall K, et al. (2018). Early Markers for Autism (EMA) Results from this large case-control study with prospectively collected prenatal measurements do not support the hypothesis that prenatal exposure to per- and polyfluoroalkyl substances is positively associated with autism spectrum disorder or intellectual disability. 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | N-ethyl perfluorooctane sulfonamido acetate | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Subjects with disease:Autism Spectrum Disorder | Children | Subjects with disease:Intellectual Disability | Pregnant females United States serum 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | N-ethyl perfluorooctane sulfonamido acetate | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details Autism Spectrum Disorder | Intellectual Disability
13. Huang YF, et al. (2017). Our results support a role for exposure to 4-nonylphenol and bisphenol A and possibly inflammation in increasing oxidative/nitrative stress and decreasing antioxidant activity during pregnancy. 4-nonylphenol | bisphenol A Pregnant females Taiwan, Province of China blood | blood, cord | urine 4-nonylphenol | 8-epi-prostaglandin F2alpha | 8-nitroguanine | 8-oxo-7-hydrodeoxyguanosine | bisphenol A | GPX1 | TNF Details negative regulation of glutathione peroxidase activity | tumor necrosis factor production
14. Fraser AJ, et al. (2013). Our investigation provides insight into concentrations of polyfluorinated compounds (PFCs) in the dust of offices, homes and vehicles in the United States and represents a novel attempt to assess contributions of different exposure media and microenvironments on PFC body burdens. 8-2 fluorotelomer alcohol | Fluorocarbons | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Workers United States dust 8-2 fluorotelomer alcohol | Fluorocarbons | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
15. Fraser AJ, et al. (2012). Fluorotelomer alcohol concentrations in office air significantly predict serum perfluorooctanoate concentrations in office workers. 8-2 fluorotelomer alcohol | Hydrocarbons, Fluorinated | perfluoroheptanoic acid Workers United States air | serum 2-(N-ethylperfluorooctanesulfonamido)ethyl alcohol | 8-2 fluorotelomer alcohol | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
16. Ferguson KK, et al. (2016). In the present mediation analysis we statistically demonstrate within a causal framework that the relationship between phthalate exposure and spontaneous preterm birth is mediated in part by phthalate-induced oxidative stress, which has not been elucidated clearly in human or animal studies previously. 8-epi-prostaglandin F2alpha | Diethylhexyl Phthalate | monobutyl phthalate Pregnant females United States urine Details Premature Birth | detection of oxidative stress
17. Luben TJ, et al. (2007). Healthy Men Study (HMS) The results of this study do not support an association between exposure to levels of disinfection by-products near or below regulatory limits and adverse sperm outcomes in humans. Acetates | Trihalomethanes | Water Pollutants, Chemical Study subjects United States Acetates | Trihalomethanes Details spermatogenesis
18. Jiménez-Garza O, et al. (2017). Our results demonstrate alterations in the inflammation pathway at the epigenetic level associated with exposure to benzene. Acetone | Benzene | ethylbenzene | methyl acetate | methylethyl ketone | n-hexane | Toluene | Xylenes Workers Mexico air Acetone | Benzene | ethylbenzene | methyl acetate | methylethyl ketone | n-hexane | Toluene | Xylenes Details Inflammation | inflammatory response | methylation
19. Lundström SL, et al. (2011). Several of the altered oxylipins have known or suspected bronchoprotective or anti-inflammatory effects, suggesting a possible reduced anti-inflammatory response in asthmatics following exposure to subway air. disease Air Pollutants Controls for disease:Asthma | Subjects with disease:Asthma Sweden lung 12,13-epoxy-9- keto-10-octadecenoic acid | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid | 13-hydroxy-9,11-octadecadienoic acid | 13-Hydroxy-octadecatrienoic acid | 13-oxo-9,11-octadecadienoic acid | 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid | 15-hydroxy-5,8,11,13-eicosatetraenoic acid | 15-hydroxyeicosatrienoic acid | 15-keto-5,8,11,13-eicosatetraenoic acid | 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid | 5,6-epoxy-8,11,14-eicosatrienoic acid | 5-hydroxy-6,8,11,14-eicosatetraenoic acid | 8,9-epoxyeicosatrienoic acid | 9,10,13-trihydroxyoctadec-11-enoic acid | 9,12,13-trihydroxy-10-octadecenoic acid | 9-hydroxy-10,12-octadecadienoic acid | 9-oxo-10,12-octadecadienoic acid | ALOX15 | Dinoprostone | Leukotriene B4 | PPARG | Prostaglandin D2 | PTGS1 | PTGS2 | Thromboxane B2 Details negative regulation of inflammatory response | oxylipin biosynthetic process
20. Virtanen JK, et al. (2014). Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) Serum long-chain omega-3 polyunsaturated fatty acids concentration, an objective biomarker for fish intake, was associated with long-term lower risk of type 2 diabetes. diet alpha-Linolenic Acid | Docosahexaenoic Acids | docosapentaenoic acid | Fatty Acids, Omega-3 | Mercury Study subjects Finland hair Mercury Details Diabetes Mellitus, Type 2
21. Kamel F, et al. (2014). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Polyunsaturated fatty acid intake was consistently associated with lower Parkinson's disease (PD) risk, and dietary fats modified the association of PD risk with pesticide exposure. alpha-Linolenic Acid | Fatty Acids | Fatty Acids, Unsaturated | Paraquat | Rotenone Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
22. McNally K, et al. (2017). In summary, our work suggests that the relationship between benzene in air and background-corrected metabolites measured in post-shift urine samples was non-linear for this population of 213 occupationally exposed workers from a shoe factory in the Tianjin region of China. Benzene | Toluene Workers China air | urine Benzene | catechol | hydroquinone | muconic acid | Phenol | S-phenyl-N-acetylcysteine | Toluene Details
23. Khan A, et al. (2017). Ewha Birth & Growth Cohort Study We conducted a high-resolution metabolomics study and detected elevated metabolites of steroidogenesis and amino acid metabolism in preadolescent female children with high urinary bisphenol A levels. sex bisphenol A Children Korea, Republic of urine 22-hydroxycholesterol | 3-methoxytyramine | aerobactin | Androstenedione | anthranilic acid | bisphenol A | Carnitine | Cholesterol | Corticosterone | cortolone | crotonyl-coenzyme A | Cytidine Monophosphate N-Acetylneuraminic Acid | cytidine monophosphate-N-glycoloylneuraminic acid | estrone sulfate | fructose-6-phosphate | glucosaminic acid | Hydrocortisone | isocaproaldehyde | Malonyl Coenzyme A | N-acetylmuramic acid | N-acetylserotonin | phenylacetylglycine | Pregnanediol | Progesterone | testosterone glucuronate Details regulation of cellular amino acid metabolic process | regulation of steroid biosynthetic process
24. Nelson JW, et al. (2012). National Health and Nutrition Examination Survey (NHANES) In these data, family income with adjustment for family size was the strongest predictor of bisphenol A and polyfluoroalkyl chemicals levels among the different measures of socioeconomic position we studied. socioeconomic status bisphenol A Children | Study subjects United States serum | urine bisphenol A | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
25. Wright JM, et al. (2017). This is the first epidemiological study of birth defects and disinfection by-products (DBPs) to examine several individual cardiovascular defects, different exposure surrogate mixtures (sum of chloroform, bromoform, bromodichloromethane, and dibromochloromethane (THM4), brominated trihalomethanes, sum of monochloroacetic acid, dichloroacetic acid, trichloroacetic acid, monobromoacetic acid, and dibromoacetic acid (HAA5), sum of THM4 and HAA5, and various individual DBP species. sex bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid Fetuses | Pregnant females United States water, drinking Acetates | bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Details Cardiovascular Abnormalities | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Pulmonary Valve Stenosis | Tetralogy of Fallot | Transposition of Great Vessels
26. Smith RB, et al. (2016). Born in Bradford (BiB) Study Our findings demonstrate associations between trihalomethane, but not haloacetic acid, exposure during pregnancy and reduced birth weight, but suggest this differs by ethnicity. race bromodichloroacetic acid | bromodichloromethane | chlorodibromomethane | Chloroform | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Pregnant females United Kingdom bromodichloroacetic acid | bromodichloromethane | chlorodibromomethane | Chloroform | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Details
27. Ellis JK, et al. (2012). This study shows evidence that metabolic profiling in an uncontrolled human population is capable of identifying intermediate biomarkers of response to cadmium at true environmental concentrations, paving the way for exposome research. Cadmium Study subjects United Kingdom urine 8-oxo-7-hydrodeoxyguanosine | beta-hydroxyisovaleric acid | Citric Acid | Creatine | Creatinine Details cellular response to oxidative stress
28. Knobeloch L, et al. (2012). In an effort to assess residential exposure, we tested vacuum cleaner dust from 39 Wisconsin homes for several perflouroalkyl chemicals; the most commonly detected compounds were perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoic acid. Dust Study subjects United States dust, indoor perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details
29. La Rocca C, et al. (2014). Our study indicates the relevance of the living environment when investigating the exposure to endocrine disrupters and the modulation of nuclear receptors (as a suitable biomarker of the effect) to assess the endocrine disrupters impact on reproductive health. Endocrine Disruptors Controls for disease:Infertility, Female | Subjects with disease:Infertility, Female Italy blood | leukocyte, mononuclear | serum AHR | AR | bisphenol A | ESR1 | ESR2 | mono-(2-ethylhexyl)phthalate | NR1I2 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
30. de Cock M, et al. (2014). We assessed the association between prenatal exposure to various endocrine disrupting chemicals and child growth during the first year; exposure to phthalates and DDE was associated with body mass index as well as with head circumference during the first year after birth; these results should be interpreted with caution though, due to the limited sample size. Endocrine Disruptors Infants or newborns Netherlands blood, cord | milk, human 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | perfluorooctane sulfonic acid | perfluorooctanoic acid Details developmental growth | head development
31. Wattigney WA, et al. (2015). National Health and Nutrition Examination Survey (NHANES) We examined serum levels of persistent organic pollutants among four geographical U.S. regions (northeast, midwest, south, and west); differences in higher body burdens of exposure could be attributed to region-specific patterns of land use, industrial and agricultural chemical applications, and different levels of regulatory activity. Environmental Pollutants Study subjects United States serum 1,2,3,4,6,7,8-heptachlorodibenzodioxin | 1,2,3,6,7,8-hexachlorodibenzodioxin | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | tribromodiphenyl ether 28 Details
32. Berg V, et al. (2017). Northern Norway Mother-and-Child Contaminant Cohort Study (MISA) The present results suggest that background exposures to persistent organic pollutants can alter maternal thyroid homeostasis. Environmental Pollutants | Hexachlorobenzene | nonachlor | perfluorodecanoic acid | perfluorooctane sulfonic acid | perfluoroundecanoic acid | Pesticides | Polychlorinated Biphenyls Pregnant females Norway serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5,5',6-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | nonachlor | PCB 180 | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Thyroxine | Triiodothyronine | TSHB Details thyroid hormone generation | thyroid-stimulating hormone secretion
33. Lemire M, et al. (2015). Nunavik Health Survey The study objectives are to identify contemporary country food sources of methylmercury, selenium and long-chain omega-3 polyunsaturated fatty acids in Nunavik, particularly among childbearing-age women, taking into account regional differences in consumption profiles. Fatty Acids, Unsaturated | Methylmercury Compounds | Selenium Study subjects Canada blood | erythrocyte Fatty Acids, Unsaturated | Mercury | Methylmercury Compounds | Selenium Details
34. Schecter A, et al. (2012). Our results show that several Polyfluoroalkyl Compounds (PFCs) were detectable in children in Dallas, Texas, in 2009, including those born after changes in PFC manufacturing occurred. Fluorocarbons Children United States serum perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
35. Kataria A, et al. (2015). National Health and Nutrition Examination Survey (NHANES) Perfluoroalkyl acids are associated with a reduction in kidney function and increased uric acid levels in otherwise healthy adolescents. Fluorocarbons Children United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid Details glomerular filtration
36. Hu XC, et al. (2018). We conclude that poly- and perfluoroalkyl substance homologue profiles in serum provide valuable information on major exposure sources. Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids Children | Study subjects Faroe Islands serum Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids Details
37. Fan H, et al. (2014). C8 Health Project (C8HP) Using 2005-2006 data from a large perfluorocarbon (PFC)-exposure population survey, we compared serum PFCs concentrations between Gilbert Syndrome (GS) and non GS clinical phenotypes, in a cross sectional design, adjusting for standard risk factors, including age, body mass index, smoking status, socioeconomic status and gender. sex Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Controls for disease:Gilbert Disease | Subjects with disease:Gilbert Disease | Study subjects United States serum Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details Gilbert Disease
38. Wang Y, et al. (2013). Norwegian Mother and Child Cohort Study (MoBa) Our results suggest an association between perfluorooctane sulfonate and thyroid stimulating hormone in pregnant women that is small and may be of no clinical significance. Fluorocarbons | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids Pregnant females Norway plasma perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids | Thyrotropin Details thyroid hormone metabolic process
39. Lopez-Espinosa MJ, et al. (2016). C8 Health Project (C8HP) We found serum perfluoroalkyl substances concentrations to be associated with lower levels of sex hormones and IGF-1 in children aged 6-9 years. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum Estradiol | IGF1 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Testosterone Details estradiol secretion | gene expression | testosterone secretion
40. Preston EV, et al. (2018). Project Viva In this study, prenatal exposure to some per- and polyfluoroalkyl substances during early pregnancy was inversely associated with maternal free thyroxine (T4) index and neonatal T4 in male infants. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Infants or newborns | Pregnant females United States plasma perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
41. Goudarzi H, et al. (2017). Sapporo Cohort, Hokkaido Study on Environment and Child Health Our results indicate that prenatal exposure to perfluorinated chemicals is significantly associated with glucocorticoid and dehydroepiandrosterone levels in cord blood. tobacco Fluorocarbons | perfluorooctane sulfonic acid | perfluorooctanoic acid Fetuses | Infants or newborns | Pregnant females Japan blood, cord | serum Androstenedione | Cortisone | Dehydroepiandrosterone | Hydrocortisone | perfluorooctane sulfonic acid | perfluorooctanoic acid Details cortisol secretion | dehydroepiandrosterone secretion
42. Shrestha S, et al. (2015). In the current study of older residents of the upper Hudson River communities, we detected positive associations between serum perfluorooctane sulfonate and free thyroxine and total thyroxine. age Halogenated Diphenyl Ethers | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls Study subjects United States serum Halogenated Diphenyl Ethers | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | Thyroxine | Triiodothyronine | TSHB Details thyroid hormone metabolic process
43. Webster GM, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We found evidence of perfluoroalkyl acids-associated thyroid disruption in a subset of U.S. adults with high thyroid peroxidase antibody (a marker of autoimmune hypothyroidism) and low iodine status, who may represent a vulnerable subgroup. sex hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum | urine hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Thyrotropin | Thyroxine | Triiodothyronine Details thyroid hormone metabolic process
44. Grandjean P, et al. (2016). Diphtheria antibody concentrations decreased at elevated perfluorinated alkylate substance concentrations at ages 13 and 7 years, associations being statistically significant for perfluorodecanoate at age 7 and perfluorooctanoate at age 13, both suggesting a decrease by about 25% for each doubling of exposure. hexadecafluoro-nonanoic acid | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children Faroe Islands serum hexadecafluoro-nonanoic acid | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details IgG immunoglobulin complex, circulating
45. Mora AM, et al. (2016). Project Viva In this cohort, prenatal exposure to PFASs was associated with small increases in adiposity measurements in mid-childhood, but only among girls. sex hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children | Pregnant females United States plasma hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid Details Obesity | adipose tissue development
46. Calafat AM, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In the general U.S. population in 2003-2004, perfluorooctane sulfonic acid, perfluorooctanoic acid, perfluorohexane sulfonic acid, and perfluorononanoic acid serum concentrations were measurable in each demographic population group studied. hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
47. Lee WC, et al. (2017). Maternal-Infant Research on Environmental Chemicals (MIREC) Study We present an approach using factor analysis through principal component method and cluster analysis as an attempt to determine the pregnancy exposome; our results show the association between certain socio-demographic characteristics of the population of pregnant women and the presence of residual mixtures of common chemicals in their blood and urine. socioeconomic status Hydrocarbons, Fluorinated | Metals | Pesticides | Plasticizers | Polychlorinated Biphenyls Pregnant females Canada blood | plasma | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Arsenic | beta-hexachlorocyclohexane | bisphenol A | Cacodylic Acid | Cadmium | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | Lead | Manganese | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | nonachlor | O,O-dimethyl phosphorothionate | oxychlordane | PCB 180 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
48. Borg D, et al. (2013). The objective of this study was to for the first time perform a cumulative health risk assessment of the 17 perfluoroalkylated and polyfluoroalkylated substances measured in the Swedish population, individually and in combination, using the Hazard Index approach. Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Study subjects | Workers Sweden serum Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details Liver Diseases | immune response | mammary gland development | reproductive process
49. Liew Z, et al. (2018). Lifestyle During Pregnancy Study-Danish National Birth Cohort (LDPS-DNBC) Overall, we did not find consistent evidence to suggest prenatal exposure to perfluoroalkyl substances to be associated with child IQ scores at 5 y of age in the Danish National Birth Cohort. Some of the sex-specific observations warrant further investigation. Hydrocarbons, Fluorinated | perfluorobutane | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoropentanoic acid | perfluoroundecanoic acid | Sulfonic Acids Children | Pregnant females Denmark plasma Hydrocarbons, Fluorinated | perfluorobutane | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoropentanoic acid | perfluoroundecanoic acid | Sulfonic Acids Details cognition
50. Weihe P, et al. (2008). To determine the prevalence and magnitude of exposure to polyfluoroalkyl compounds (PFCs) in the Faroe Islands, we measured the serum concentrations of 9 PFCs in two Faroese population groups. Hydrocarbons, Halogenated Children | Pregnant females Faroe Islands serum perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
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