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Chemical Floxuridine

Name Floxuridine
CAS Type 1 Name Uridine, 2'-deoxy-5-fluoro-
Equivalent Terms 5 Fluorodeoxyuridine | 5-Fluorodeoxyuridine | 5-FUdR | Fluorodeoxyuridine | FUdR
CAS Registry Number 50-91-9
Definition An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Structure Floxuridine
Top Interacting
Genes
MeSH® ID D005467
External Links

Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Pyrimidines Has associated genes Has associated diseases Has associated exposure references Pyrimidine Nucleosides Has associated genes Has associated diseases Uridine Has associated genes Has associated diseases Deoxyuridine Has associated genes Has associated diseases Floxuridine Has associated genes Has associated diseases
2. ChemicalsNucleic Acids, Nucleotides, and Nucleosides Has associated genes Has associated diseases Has associated exposure references Nucleosides Has associated genes Has associated diseases Has associated exposure references Deoxyribonucleosides Has associated genes Has associated diseases Has associated exposure references Deoxyuridine Has associated genes Has associated diseases Floxuridine Has associated genes Has associated diseases
3. ChemicalsNucleic Acids, Nucleotides, and Nucleosides Has associated genes Has associated diseases Has associated exposure references Nucleosides Has associated genes Has associated diseases Has associated exposure references Pyrimidine Nucleosides Has associated genes Has associated diseases Uridine Has associated genes Has associated diseases Deoxyuridine Has associated genes Has associated diseases Floxuridine Has associated genes Has associated diseases

Top ↑ Descendants

Floxuridine Has associated genes Has associated diseases
  1-(2-deoxy-2-fluoro-3-O-(1-methyl-1,4-dihydropyridyl-3-carbonyl)ribofuranosyl)-5-(2-iodovinyl)uracil
  1-(2'-deoxy-2'-fluororibofuranosyl)-5-dodecynyluracil
  1-(2'-deoxy-2'-fluororibofuranosyl)-5-tetradecynyluracil
  2',2'-difluoro-2'-deoxyuridine
  2'-amino-2'-deoxy-5-fluorouridine
  2'-deoxy-2',4'-difluorouridine
  2'-deoxy-3',5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine
  2'-deoxy-5-fluorouridylyl-(3'-5')-2'-deoxy-5-fluoro-N(4)-octadecylcytidine
  2'fluoro-2'-deoxyuridine
  3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine
  3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine
  3'-azido-2',3'-dideoxy-5-fluorouridine phosphoramidate
  3'-O-crotonylfloxuridine
  3'-octanoyl-5-fluoro-2'-deoxyuridine
  5'-(2-(2-Nitrophenyl)-2-methylpropionyl)-2'-deoxy-5-fluorouridine
  5-(2-fluoroethyl)-2'-deoxyuridine
  5-(2-iodovinyl)-1-(2'-fluoro-2'-deoxyuridine)
  5-bromo-1-(2-fluoro-2-deoxyribofuranosyl)uracil
  5-chloro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil
  5'deoxy-4',5-difluorouridine
  5-fluoro-1-(2'-deoxy-2'-fluoro-ribofuranosyl)uracil
  5-fluoro-1-(2'-fluoro-2'-deoxyribofuranosyl)uracil
  5-fluoro-2'-deoxyuridylyl-(3'-5')-arabinocytidine
  5-fluoro-5'-O-nitro-2'-deoxyuridine
  5-fluorodeoxyuridine-dipalmitate
  5-iodo-1-(2-fluoro-2-deoxyribofuranosyl)uracil
  5'-isoleucyl-glycyl-floxuridine
  5'-octanoyl-5-fluoro-2'-deoxyuridine
  5'-O-palmitoyl-5-fluoro-2'-deoxyuridine
  5'-phenylalanyl-glycyl-floxuridine
  5'-phenylalanyl-tyrosyl-floxuridine
  BOF A1
  DAC protocol 2
  doxifluridine Has associated genes Has associated diseases
  FF 707
  FLAP protocol
  fluorodeoxyuridine triphosphate
  FMB protocol
  FUDRAM protocol
  MAC-VD protocol
  N(3)-methyl-5'-deoxy-5-fluorouridine
  N(4)-palmitoyl-2'-deoxycytidylyl-(3'-5')-5-fluoro-2'-deoxyuridine
  NUC-3073
  thymidylyl-(3'-5')-2'-deoxy-5-fluorouridine
  TK 117