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Chemical Folic Acid Antagonists

Name Folic Acid Antagonists
Equivalent Terms Acid Antagonists, Folic | Antagonists, Folic Acid | Antifolates | Dihydrofolate Reductase Inhibitors | Folic Acid Metabolism Inhibitors | Inhibitors, Dihydrofolate Reductase | Reductase Inhibitors, Dihydrofolate
Definition Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)
Top Interacting
Genes
MeSH® ID D005493
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ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Molecular Mechanisms of Pharmacological Action Has associated genes Has associated diseases Has associated exposure references Enzyme Inhibitors Has associated genes Has associated diseases Has associated exposure references Folic Acid Antagonists Has associated genes Has associated diseases

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None.