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Chemical G(M3) Ganglioside

Name G(M3) Ganglioside
Equivalent Terms Ganglioside GM3 | GM3, Ganglioside | Hematoside | II3NeuAcLacCer | Lactosylceramide, Sialyl | Sialyllactosylceramide | Sialyl Lactosylceramide
Definition A ganglioside present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, G(M3):UDP-N-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of G(M2) ganglioside from G(M3) ganglioside and is the cause of an anabolic sphingolipidosis.
Top Interacting
Genes
MeSH® ID D005679
External Links
PubChem
D005679
TOXLINE®
Query

Top ↑ Ancestors

1. Chemicals ← Carbohydrates Has associated genes Has associated diseases Has associated exposure references ← Glycoconjugates Has associated genes Has associated diseases ← Glycolipids Has associated genes Has associated diseases ← Glycosphingolipids Has associated genes Has associated diseases ← Acidic Glycosphingolipids Has associated genes Has associated diseases ← Gangliosides Has associated genes Has associated diseases ← G(M3) Ganglioside Has associated genes Has associated diseases
2. Chemicals ← Lipids Has associated genes Has associated diseases Has associated exposure references ← Glycolipids Has associated genes Has associated diseases ← Glycosphingolipids Has associated genes Has associated diseases ← Acidic Glycosphingolipids Has associated genes Has associated diseases ← Gangliosides Has associated genes Has associated diseases ← G(M3) Ganglioside Has associated genes Has associated diseases
3. Chemicals ← Lipids Has associated genes Has associated diseases Has associated exposure references ← Membrane Lipids Has associated genes Has associated diseases Has associated exposure references ← Sphingolipids Has associated genes Has associated diseases ← Glycosphingolipids Has associated genes Has associated diseases ← Acidic Glycosphingolipids Has associated genes Has associated diseases ← Gangliosides Has associated genes Has associated diseases ← G(M3) Ganglioside Has associated genes Has associated diseases

Top ↑ Descendants

G(M3) Ganglioside Has associated genes Has associated diseases
  4-O-acetyl-N-glycolylneuraminyl lactosylceramide
  5-acetamido-3,4,5,8-tetradeoxy-lyxo-2-nonulopyranosylonic acid-2-3-galactopyranosyl-1-4-glucopyranosyl-(1-1)-2-octadecanamido-4-octadecene-1,3-diol
  de-N-acetylneuraminyllactosylceramide
  ganglioside GM3 lactam
  ganglioside GM3 lactone
  lyso-G(M3) ganglioside
  N-acetylneuraminosyl-2-6-galactosyl-1-4-glucopyranosyl-1-1-ceramide
  N-glycolylneuraminyllactosylceramide